Publications

201.

Journal Article

Savelsbergh, A.; Katunin, V. I.; Mohr, D.; Peske, F.; Rodnina, M. V.; Wintermeyer, W.: An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation. Molecular Cell 11, pp. 1517 - 1523 (2003)

MPG.PuRe

publisher-version

202.

Journal Article

Stark, H.; Rodnina, M. V.; Wieden, H. J.; Zemlin, F.; Wintermeyer, W.; van Heel, M.: Ribosome interactions of aminoacyl-tRNA and elongation factor Tu in the codon-recognition complex. Nature Structural Biology 9 (11), pp. 849 - 854 (2002)

MPG.PuRe

203.

Journal Article

Rodnina, M. V.; Daviter, T.; Gromadski, K. B.; Wintermeyer, W.: Structural dynamics of ribosomal RNA during decoding on the ribosome. Biochimie 84 (8), pp. 745 - 754 (2002)

MPG.PuRe

204.

Journal Article

Wieden, H. J.; Gromadski, K. B.; Rodnin, D. N.; Rodnina, M. V.: Mechanism of elongation factor (EF)-Ts-catalyzed nucleotide exchange in EF-Tu: Contribution of contacts at the guanine base. Journal of Biological Chemistry 277 (8), pp. 6032 - 6036 (2002)

MPG.PuRe

publisher-version

205.

Journal Article

Gromadski, K. B.; Wieden, H. J.; Rodnina, M. V.: Kinetic mechanism of elongation factor Ts-catalyzed nucleotide exchange in elongation factor Tu. Biochemistry 41 (1), pp. 162 - 169 (2002)

MPG.PuRe

206.

Journal Article

Katunin, V. I.; Muth, G. W.; Strobel, S. A.; Wintermeyer, W.; Rodnina, M. V.: Important contribution to catalysis of peptide bond formation by a single ionizing group within the ribosome. Molecular Cell 10, pp. 339 - 346 (2002)

MPG.PuRe

publisher-version

207.

Journal Article

Katunin, V. I.; Savelsbergh, A.; Rodnina, M. V.; Wintermeyer, W.: Coupling of GTP hydrolysis by elongation factor G to translocation and factor recycling on the ribosome. Biochemistry 41 (42), pp. 12806 - 12812 (2002)

MPG.PuRe

208.

Journal Article

Mohr, D.; Wintermeyer, W.; Rodnina, M. V.: GTPase activation of elongation factors Tu and G on the ribosome. Biochemistry 41 (41), pp. 12520 - 12528 (2002)

MPG.PuRe

209.

Journal Article

Schirmer, J.; Wieden, H. J.; Rodnina, M. V.; Aktories, K.: Inactivation of the elongation factor Tu by mosquitocidal toxin-catalyzed mono-ADP-ribosylation. Applied and Environmental Microbiology 68 (10), pp. 4894 - 4899 (2002)

MPG.PuRe

210.

Journal Article

Rodnina, M. V.; Semenkov, Y. P.; Savelsbergh, A.; Katunin, V. I.; Peske, F.; Wilden, B.; Wintermeyer, W.: Mechanism of tRNA translocation on the ribosome. Molecular Biology 35 (4), pp. 559 - 568 (2001)

MPG.PuRe

211.

Journal Article

Rodnina, M. V.; Wintermeyer, W.: Ribosome fidelity: tRNA discrimination, proofreading and induced fit. Trends in Biochemical Science 26 (2), pp. 124 - 130 (2001)

MPG.PuRe

publisher-version

212.

Journal Article

Wieden, H. J.; Wintermeyer, W.; Rodnina, M. V.: A common structural motif in elongation factor Ts and ribosomal protein L7/12 may be involved in the interaction with elongation factor Tu. Journal of Molecular Evolution 52 (2), pp. 129 - 136 (2001)

MPG.PuRe

213.

Journal Article

Jagath, J. R.; Matassova, N. B.; de Leeuw, E.; Warnecke, J. M.; Lentzen, G.; Rodnina, M. V.; Luirink, J.; Wintermeyer, W.: Important role of the tetraloop region of 4.5S RNA in SRP binding to its receptor FtsY. RNA 7 (2), pp. 293 - 301 (2001)

MPG.PuRe

publisher-version

214.

Journal Article

Matassova, N. B.; Rodnina, M. V.; Wintermeyer, W.: Elongation factor G-induced structural change in helix 34 of 16S rRNA related to translocation on the ribosome. RNA 7 (12), pp. 1879 - 1885 (2001)

MPG.PuRe

215.

Journal Article

Matassova, N. B.; Rodnina, M. V.; Wintermeyer, W.: Elongation factor G-induced structural change in helix 34 of 16S rRNA related to translocation on the ribosome. RNA 7 (12), pp. 1879 - 1885 (2001)

MPG.PuRe

publisher-version

216.

Journal Article

Rodnina, M. V.; Wintermeyer, W.: Fidelity of aminoacyl-tRNA selection on the ribosome: kinetic and structural mechanisms. Annual Review of Biochemistry 70, pp. 415 - 435 (2001)

MPG.PuRe

DOI

217.

Journal Article

Peske, F.; Matassova, N. B.; Savelsbergh, A.; Rodnina, M. V.; Wintermeyer, W.: Conformationally restricted elongation factor G retains GTPase activity but is inactive in translocation on the ribosome. Molecular Cell 6 (2), pp. 501 - 505 (2000)

MPG.PuRe

DOI

publisher-version

218.

Journal Article

Savelsbergh, A.; Matassova, N. B.; Rodnina, M. V.; Wintermeyer, W.: Role of domains 4 and 5 in elongation factor G functions on the ribosome. Journal of Molecular Biology 300 (4), pp. 951 - 961 (2000)

MPG.PuRe

DOI

219.

Journal Article

Mohr, D.; Wintermeyer, W.; Rodnina, M. V.: Arginines 29 and 59 of elongation factor G are important for GTP hydrolysis or translocation on the ribosome. EMBO Journal 19 (13), pp. 3458 - 3464 (2000)

MPG.PuRe

DOI

publisher-version

220.

Journal Article

Tomsic, J.; Vitali, L.; Daviter, T.; Savelsbergh, A.; Spurio, R.; Striebeck, P.; Wintermeyer, W.; Rodnina, M. V.; Gualerzi, C. O.: Late events of translation initiation in bacteria: a kinetic analysis. EMBO Journal 19 (9), pp. 2127 - 2136 (2000)

MPG.PuRe

DOI

publisher-version

221.

Journal Article

Piepenburg, O.; Pape, T.; Pleiss, J. A.; Wintermeyer, W.; Uhlenbeck, O. C.; Rodnina, M. V.: Intact aminoacyl-tRNA is required to trigger GTP hydrolysis by elongationfFactor Tu on the ribosome. Biochemistry 39 (7), pp. 1734 - 1738 (2000)

MPG.PuRe

DOI

222.

Journal Article

Jagath, J. R.; Rodnina, M. V.; Wintermeyer, W.: Conformational changes in the bacterial SRP receptor FtsY upon binding of guanine nucleotides and SRP. Journal of Molecular Biology 295 (4), pp. 745 - 753 (2000)

MPG.PuRe

DOI

223.

Journal Article

Savelsbergh, A.; Mohr, D.; Wilden, B.; Wintermeyer, W.; Rodnina, M. V.: Stimulation of the GTPase activity of translation elongation factor G by ribosomal protein L7/12. Journal of Biology Chemistry 275 (2), pp. 890 - 894 (2000)

MPG.PuRe

DOI

publisher-version

224.

Journal Article

Pape, T.; Wintermeyer, W.; Rodnina, M. V.: Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome. Nature Structural Biology 7 (2), pp. 104 - 107 (2000)

MPG.PuRe

DOI

publisher-version

225.

Journal Article

Rodnina, M. V.; Stark, H.; Savelsbergh, A.; Wieden, H. J.; Mohr, D.; Matassova, N. B.; Peske, F.; Daviter, T.; Gualerzi, C. O.; Wintermeyer, W.: GTPases mechanisms and functions of translation factors on the ribosome. Biological Chemistry 381, pp. 377 - 387 (2000)

MPG.PuRe

226.

Journal Article

Semenkov, Y. P.; Rodnina, M. V.; Wintermeyer, W.: Energetic contribution of tRNA hybrid state formation to translocation catalysis on the ribosome. Nature Structural Biology 7 (11), pp. 1027 - 1031 (2000)

MPG.PuRe

DOI

publisher-version

227.

Journal Article

Wintermeyer, W.; Rodnina, M. V.: Translational elongation factor G: a GTP-driven motor of the ribosome. Essays in Biochemistry 35, pp. 117 - 129 (2000)

MPG.PuRe

228.

Journal Article

Rodnina, M. V.; Savelsbergh, A.; Matassova, N. B.; Katunin, V. I.; Semenkov, Y. P.; Wintermeyer, W.: Thiostrepton inhibits the turnover but not the GTPase of elongation factor G on the ribosome. Proceedings of the National Academy of Science of the United States of America 96 (17), pp. 9586 - 9590 (1999)

MPG.PuRe

publisher-version

229.

Journal Article

Matassova, N. B.; Rodnina, M. V.; Endermann, R.; Kroll, H. P.; Pleiss, U.; Wild, H.; Wintermeyer, W.: Ribosomal RNA is the target for oxazolidinones, a novel class of translational inhibitors. RNA 5 (7), pp. 939 - 947 (1999)

MPG.PuRe

publisher-version

230.

Journal Article

Rodnina, M. V.; Savelsbergh, A.; Wintermeyer, W.: Dynamics of translation on the ribosome: molecular mechanics of translocation. FEMS Microbiology Reviews 23 (3), pp. 317 - 333 (1999)

MPG.PuRe

DOI

231.

Journal Article

Borowski, C.; Rodnina, M. V.; Wintermeyer, W.: Truncated elongation factor G lacking the G domain promotes translocation of the 3' end but not of the anticodon domain of peptidyl-tRNA. Proceedings of the National Academy of Sciences USA 93 (9), pp. 4202 - 4206 (1999)

MPG.PuRe

232.

Journal Article

Pape, T.; Wintermeyer, W.; Rodnina, M. V.: Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E.coli ribosome. EMBO Journal 17 (24), pp. 7490 - 7497 (1998)

MPG.PuRe

DOI

publisher-version

233.

Journal Article

Jagath, J. R.; Rodnina, M. V.; Lentzen, G.; Wintermeyer, W.: Interaction of guanine nucleotides with the signal recognition particle from Escherichia coli. Biochemistry 37 (44), pp. 15408 - 15413 (1998)

MPG.PuRe

DOI

234.

Journal Article

Rodnina, M. V.; Wintermeyer, W.: Form follows function: structure of an elongation factor G-ribosome complex. Proceedings of the National Academy of Scienes of the United States of America 95 (13), pp. 7237 - 7239 (1998)

MPG.PuRe

235.

Journal Article

Stark, H.; Orlova, E. V.; Rinke-Appel, J.; Juenke, N.; Mueller, F.; Rodnina, M. V.; Wintermeyer, W.; Brimacombe, R.; van Heel, M.: Arrangement of tRNAs in pre- and posttranslocational ribosomes revealed by electron cryomicroscopy. Cell 88 (1), pp. 19 - 28 (1997)

MPG.PuRe

DOI

236.

Journal Article

Rodnina, M. V.; Savelsbergh, A.; Katunin, V. I.; Wintermeyer, W.: Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome. Nature 385 (6611), pp. 37 - 41 (1997)

MPG.PuRe

DOI

237.

Journal Article

Vorstenbosch, E.; Pape, T.; Rodnina, M. V.; Kraal, B.; Wintermeyer, W.: The G222D mutation in elongation factor Tu inhibits the codon-induced conformational changes leading to GTPase activation on the ribosome. EMBO Journal 15 (23), pp. 6766 - 6774 (1996)

MPG.PuRe

publisher-version

238.

Journal Article

Semenkov, Y. P.; Rodnina, M. V.; Wintermeyer, W.: The "allosteric three-site model" of elongation cannot be confirmed in a well-defined ribosome system from Escherichia coli. Proceedings of the National Academy of Scienes of the United States of America 93 (22), pp. 12183 - 12188 (1996)

MPG.PuRe

239.

Journal Article

Borowski, C.; Rodnina, M. V.; Wintermeyer, W.: Truncated elongation factor G lacking the G domain promotes translocation of the 3' end but not of the anticodon domain of peptidyl-tRNA. Proceedings of the National Academy of Scienes of the United States of America 93 (9), pp. 4202 - 4206 (1996)

MPG.PuRe

240.

Journal Article

Rodnina, M. V.; Pape, T.; Fricke, R.; Kuhn, L.; Wintermeyer, W.: Initial binding of the elongation factor Tu GTP aminoacyl-tRNA complex preceding codon recognition on the ribosome. The Journal of Biological Chemistry 271 (2), pp. 646 - 652 (1996)

MPG.PuRe

publisher-version

241.

Journal Article

Rodnina, M. V.; Pape, T.; Fricke, R.; Wintermeyer, W.: Elongation factor Tu, a GTPase triggered by codon recognition on the ribosome: mechanism and GTP consumption. Biochemistry and Cell Biology 73 (11-12), pp. 1221 - 1227 (1995)

MPG.PuRe

242.

Journal Article

Rodnina, M. V.; Fricke, R.; Kuhn, L.; Wintermeyer, W.: Codon-dependent conformational change of elongation factor Tu preceding GTP hydrolysis on the ribosome. EMBO Journal 14 (11), pp. 2613 - 2619 (1995)

MPG.PuRe

publisher-version

243.

Journal Article

Zeidler, W.; Egle, C.; Ribeiro, S.; Wagner, A.; Katunin, V. I.; Kreutzer, R.; Rodnina, M. V.; Wintermeyer, W.; Sprinzl, M.: Site-directed mutagenesis of thermus thermophilus elongation factor Tu. Replacement of His85, Asp81 and Arg300. European Journal of Biochemistry 229 (3), pp. 596 - 604 (1995)

MPG.PuRe

244.

Journal Article

Rodnina, M. V.; Wintermeyer, W.: GTP consumption of elongation factor Tu during translation of heteropolymeric mRNAs. Proceedings of the National Academy of Scienes of the United States of America 92 (6), pp. 1945 - 1949 (1995)

MPG.PuRe

245.

Journal Article

Rodnina, M. V.; Fricke, R.; Wintermeyer, W.: Transient conformational states of aminoacyl-tRNA during ribosome binding catalyzed by elongation factor Tu. Biochemistry 33 (40), pp. 12267 - 12275 (1994)

MPG.PuRe

DOI

246.

Journal Article

Rodnina, M. V.; Serebryanik, A. I.; Ovcharenko, G. V.; El'skaya, A. V.: ATPase strongly bound to higher eukaryotic ribosomes. European Journal of Biochemistry 225 (1), pp. 305 - 310 (1994)

MPG.PuRe

DOI

247.

Journal Article

Rodnina, M. V.; Wintermeyer, W.: Two tRNA-binding sites in addition to A and P sites on eukaryotic ribosomes. Journal of Molecular Biology 228 (2), pp. 450 - 459 (1992)

MPG.PuRe

DOI

248.

Journal Article

Rodnina, M. V.; El'skaya, A. V.; Semenkov, Y. P.; Kirillov, S. V.: Interaction of tRNA with the A and P sites of rabbit-liver 80S ribosomes and their 40S subunits. European Journal of Biochemistry 185 (3), pp. 563 - 568 (1989)

MPG.PuRe

DOI

publisher-version

249.

Journal Article

Rodnina, M. V.: Models of the elongation cycle: Two or three tRNA binding sites on the ribosome? Biopolimery i kletka = Biopolymers and cell 5, pp. 5 - 14 (1989)

MPG.PuRe

250.

Journal Article

Rodnina, M. V.; El'skaya, A. V.; Semenkov, Y. P.; Kirillov, S. V.: Number of tRNA binding sites on 80 S ribosomes and their subunits. FEBS Letters 231 (1), pp. 71 - 74 (1988)

MPG.PuRe

DOI

Journal Article (253)