Zeitschriftenartikel (274)

201.
Zeitschriftenartikel
Mbefo, M. K.; Paleologou, K. E.; Boucharaba, A.; Oueslati, A.; Schell, H.; Fournier, M.; Olschewski, D.; Yin, G.; Zweckstetter, M.; Masliah, E. et al.; Kahle, P. J.; Hirling, H.; Lashuel, H. A.: Phosphorylation of synucleins by members of the polo-like kinase family. Journal of Biological Chemistry 285 (4), S. 2807 - 2822 (2010)
202.
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Salmon, L.; Nodet, G.; Oezenne, V.; Yin, G.; Jensen, M. R.; Zweckstetter, M.; Blackledge, M.: NMR characterization of long-range order in intrinsically disordered proteins. Journal of the American Chemical Society 132 (24), S. 8407 - 8418 (2010)
203.
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Skora, L.; Becker, S.; Zweckstetter, M.: Molten globule precursor states are conformationally correlated to amyloid fibrils of human β-2-microglobulin. Journal of the American Chemical Society 132 (27), S. 9223 - 9225 (2010)
204.
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Lamberto, G. R.; Binolfi, A.; Orcelett, M. L.; Bertoncini, C. O.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation. Proceedings of the National Academy of Sciences of the United States of America 106 (50), S. 21057 - 21062 (2009)
205.
Zeitschriftenartikel
Kim, H. Y.; Cho, M. K.; Kumar, A.; Maier, E.; Siebenhaar, C.; Becker, S.; Fernandez, C. O.; Lashuel, H. A.; Benz, R.; Lange, A. et al.; Zweckstetter, M.: Structural properties of pore-forming oligomers of α-synuclein. Journal of the American Chemical Society 131 (47), S. 17482 - 17489 (2009)
206.
Zeitschriftenartikel
Fischer, D.; Mukrasch, M. D.; Biernat, J.; Bibow, S.; Blackledge, M.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Conformational changes specific for pseudophosphorylation at Ser262 selectively impair binding of tau to microtubules. Biochemistry 48 (42), S. 10047 - 10055 (2009)
207.
Zeitschriftenartikel
Jensen, M. R.; Markwick, P. R.; Meier, S.; Griesinger, C.; Zweckstetter, M.; Grzesiek, S.; Bernado, P.; Blackledge, M.: Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure 17 (9), S. 1169 - 1185 (2009)
208.
Zeitschriftenartikel
Ouertatani-Sakouhi, H.; El-Turk, F.; Fauvet, B.; Roger, T.; Le Roy, D.; Karpinar, P.; Leng, L.; Bucala, R.; Zweckstetter, M.; Calandra, T. et al.; Lashuel, H. A.: A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor. Biochemistry 48 (41), S. 9858 - 9870 (2009)
209.
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Cho, M. K.; Nodet, G.; Kim, H. K.; Jensen, M. R.; Bernado, P.; Fernandez, C. O.; Becker, S.; Blackledge, M.; Zweckstetter, M.: Structural characterization of α-synuclein in an aggregation prone state. Protein Science 18 (9), S. 1840 - 1846 (2009)
210.
Zeitschriftenartikel
Karpinar, P.; Gajula Balija, M. B.; Kügler, S.; Opazo, F.; Rezaei-Ghaleh, N.; Wender, N.; Kim, H. Y.; Taschenberger, G.; Falkenburger, B. H.; Heise, H. et al.; Kumar, A.; Riedel, D.; Fichtner, L.; Voigt, A.; Braus, G. H.; Giller, K.; Becker, S.; Herzig, A.; Baldus, M.; Jäckle, H.; Eimer, S.; Schulz, J. B.; Griesinger, C.; Zweckstetter, M.: Pre-fibrillar α-synuclein variants with impaired bold β-structure increase neurotoxicity in Parkinson's disease models. EMBO Journal 28 (20), S. 3256 - 3268 (2009)
211.
Zeitschriftenartikel
Mukrasch, M.; Bibow, S.; Korukottu, J.; Jeganathan, S.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Structural polymorphism of 441-residue tau at single residue resolution. PLoS Biology 7 (2), e1000034 (2009)
212.
Zeitschriftenartikel
Rezaei-Ghaleh, N.; Zweckstetter, M.; Morshedi, D.; Ebrahim-Habibi, A.; Nehmat-Gorgani, M.: Amyloidogenic potential of α-chymotrypsin in different conformational states. Biopolymers 91 (1), S. 28 - 36 (2009)
213.
Zeitschriftenartikel
Coudevylle, N.; Montaville, P.; Leonov, M.; Zweckstetter, M.; Becker, S.: Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A. Journal of Biological Chemistry 283 (51), S. 35918 - 35928 (2008)
214.
Zeitschriftenartikel
Rumpel, S.; Lakshmi, R.; Becker, S.; Zweckstetter, M.: Assignment-free solution NMR method reveals CesT as an unswapped homodimer. Protein Science 17 (11), S. 2015 - 2019 (2008)
215.
Zeitschriftenartikel
Soragni, A.; Zambelli, B.; Mukrasch, M.; Biernat, J.; Jeganathan, S.; Griesinger, C.; Ciurli, S.; Mandelkow, E.; Zweckstetter, M.: Structural characterization of binding of Cu(II) to Tau protein. Biochemistry 47 (41), S. 10841 - 10851 (2008)
216.
Zeitschriftenartikel
Bayrhuber, M.; Meins, T.; Habeck, M.; Becker, S.; Giller, K.; Villinger, S.; Vonrhein, C.; Griesinger, C.; Zweckstetter, M.; Zeth, K.: Structure of the human voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 105 (40), S. 15370 - 15375 (2008)
217.
Zeitschriftenartikel
El-Turk, F.; Cascella, M.; Ouertatami-Sakonhi, H.; Lakshmi, R. N.; Leng, L.; Bucala, R.; Zweckstetter, M.; Rothlisberger, U.; Lashuel, H. A.: The conformational flexibility of the carboxy terminal residues 105−114 Is a key modulator of the catalytic activity and stability of macrophage migration inhibitory factor. Biochemistry 47 (40), S. 10740 - 10756 (2008)
218.
Zeitschriftenartikel
Binolfi, A.; Lamberto, G. R.; Duran, R.; Quintanar, L.; Bertoncini, C. W.; Souza, J. M.; Cervenansky, C.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Site-specific interactions of Cu(II) with α and β-synuclein: bridging the molecular gap between metal binding and aggregation. Journal of the American Chemical Society 130 (35), S. 11801 - 11812 (2008)
219.
Zeitschriftenartikel
Kim, H. Y.; Cho, M. K.; Riedel, D.; Fernandez, C. O.; Zweckstetter, M.: Dissociation of amyloid fibrils of α-synuclein in supercooled water. Angewandte Chemie International Edition 47 (27), S. 5046 - 5048 (2008)
220.
Zeitschriftenartikel
Korukottu, J.; Schneider, R.; Vijayan, V.; Lange, A.; Pongs, O.; Becker, S.; Baldus, M.; Zweckstetter, M.: High-resolution 3D structure determination of kaliotoxin by solid-state NMR spectroscopy. PLoS One 3 (6), e2359 (2008)
221.
Zeitschriftenartikel
Paleologou, K. E.; Schmid, A. W.; Rospigliosi, C. C.; Kim, H. Y.; Lamberto, G. R.; Fredenburg, R. A.; Lansbury, P. T.; Fernandez, C. O.; Eliezer, D.; Zweckstetter, M. et al.; Lashuel, H. A.: Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of α-synuclein. The Journal of Biological Chemistry 283, S. 16895 - 16905 (2008)
222.
Zeitschriftenartikel
Sevvana, M.; Vijayan, V.; Zweckstetter, M.; Reinelt, S.; Madden, D. R.; Herbst-Irmer, R.; Sheldrick, G. M.; Bott, M.; Griesinger, C.; Becker, S.: A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA. Journal of Molecular Biology 377 (2), S. 512 - 523 (2008)
223.
Zeitschriftenartikel
Zweckstetter, M.: NMR: prediction of molecular alignment from structure using the PALES software. Nature Protocols 3 (4), S. 679 - 690 (2008)
224.
Zeitschriftenartikel
Montaville, P.; Condevylle, N.; Radhakrishnan, A.; Leonov, A.; Zweckstetter, M.; Becker, S.: The PIP2 binding mode of the C2 domains of rabphilin-3A. Protein Science 17 (6), S. 1025 - 1034 (2008)
225.
Zeitschriftenartikel
Rumpel, S.; Becker, S.; Zweckstetter, M.: High-resolution structure determination of the CylR2 homodimer using paramagnetic relaxation enhancement and structure-based prediction of molecular alignment. Journal of Biomolecular NMR 40 (1), S. 1 - 13 (2008)
226.
Zeitschriftenartikel
Bertoncini, C. W.; Rasia, R. M.; Lamberto, G. R.; Binolfi, A.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation. Journal of Molecular Biology 372 (3), S. 708 - 722 (2007)
227.
Zeitschriftenartikel
Mukrasch, M.; von Bergen, M.; Biernat, J.; Fischer, D.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: The "jaws" of the tau-microtubule interaction. Journal of Biological Chemistry 282 (16), S. 12230 - 12239 (2007)
228.
Zeitschriftenartikel
Cho, M. K.; Kim, H. Y.; Bernado, P.; Fernandez, C. O.; Blackledge, M.; Zweckstetter, M.: Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau. Journal of the American Chemical Society 129 (11), S. 3032 - 3033 (2007)
229.
Zeitschriftenartikel
Fischer, D.; Mukrasch, M.; von Bergen, M.; Klos-Witkowska, A.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Structural and microtubule binding properties of tau mutants of frontotemporal dementias. Biochemistry 46 (10), S. 2574 - 2582 (2007)
230.
Zeitschriftenartikel
Montaville, P.; Schlicker, C.; Leonov, A.; Zweckstetter, M.; Sheldrick, G. M.; Becker, S.: The C2A-C2B linker defines the high affinity Ca2+ binding mode of rabphilin-3A. Journal of Biological Chemistry 282 (7), S. 5015 - 5025 (2007)
231.
Zeitschriftenartikel
Kim, H. Y.; Heise, H.; Fernandez, C. O.; Baldus, M.; Zweckstetter, M.: Correlation of amyloid fibril beta-structure with the unfolded state of alpha-synuclein. ChemBioChem 8 (14), S. 1671 - 1674 (2007)
232.
Zeitschriftenartikel
Korukottu, J.; Bayrhuber, M.; Montaville, P.; Jung, Y. S.; Vijayan, V.; Becker, S.; Zweckstetter, M.: Fast high-resolution protein structure determination by using unassigned NMR data. Angewandte Chemie International Edition 46 (7), S. 1176 - 1179 (2007)
233.
Zeitschriftenartikel
Mukrasch, M.; Markwick, P.; Biernat, J.; von Bergen, M.; Bernado, P.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.; Blackledge, M.: Highly populated turn conformations in natively unfolded Tau protein identified from residual dipolar couplings and molecular simulation. Journal of the American Chemical Society 129 (16), S. 5235 - 5243 (2007)
234.
Zeitschriftenartikel
Iwahara, J.; Zweckstetter, M.; Clore, G. M.: NMR structural and kinetic characterization of a homeodomain diffusing and hopping on nonspecific DNA. Proceedings of the National Academy of Sciences of the United States of America 103 (41), S. 15062 - 15067 (2006)
235.
Zeitschriftenartikel
Watzlawik, J.; Skora, L.; Frense, D.; Griesinger, C.; Zweckstetter, M.; Schulz-Schaeffer, W.; Kramer, M. L.: Prion protein helix1 promotes aggregation but is not converted into beta-sheet. Journal of Biological Chemistry 281 (40), S. 30242 - 30250 (2006)
236.
Zeitschriftenartikel
Ab, E.; Atkinson, A. R.; Banci, L.; Bertini, I.; Ciofi-Baffoni, S.; Brunner, K.; Diercks, T.; Dötsch, V.; Engelke, F.; Folkers, G. E. et al.; Griesinger, C.; Gronwald, W.; Günther, U.; Habeck, M.; De Jong, R. N.; Kalbitzer, H. R.; Kieffer, B.; Leeflang, B. R.; Loss, S.; Luchinat, C.; Marquardsen, T.; Moskau, D.; Neidig, K. P.; Nilges, M.; Piccioli, M.; Pierattelli, R.; Rieping, W.; Schippmann, T.; Schwalbe, H.; Travé, G.; Trenner, J.; Wöhnert, J.; Zweckstetter, M.; Kaptein, R.: NMR in the SPINE structural proteomics project. Acta Crystallographica Section D-Biological Crystallography 62 (10), S. 1150 - 1161 (2006)
237.
Zeitschriftenartikel
Jauch, R.; Cho, M. K.; Jaekel, S.; Netter, C.; Schreiter, K.; Aicher, B.; Zweckstetter, M.; Jaeckle, H.; Wahl, M. C.: Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment. The EMBO Journal 25 (17), S. 4020 - 4032 (2006)
238.
Zeitschriftenartikel
Binolfi, A.; Rasia, R. M.; Bertoncini, C. W.; Ceolin, M.; Zweckstetter, M.; Griesinger, C.; Jovin, T. M.; Fernandez, C. O.: Interaction of alpha-synuclein with divalent metal ions reveals key differences: A link between structure, binding specificity and fibrillation enhancement. Journal of the American Chemical Society 128 (30), S. 9893 - 9901 (2006)
239.
Zeitschriftenartikel
Bayrhuber, M.; Graf, R.; Ferber, M.; Zweckstetter, M.; Imperial, J.; Garrett, J. E.; Olivera, B. M.; Terlau, H.; Becker, S.: Production of recombinat Conkunitzin-S1 in Escherichia coli. Protein Expression and Purification 47 (2), S. 640 - 644 (2006)
240.
Zeitschriftenartikel
Skora, L.; Cho, M. K.; Kim, H. Y.; Becker, S.; Fernandez, C. O.; Blackledge, M.; Zweckstetter, M.: Charge-induced molecular alignment of intrinsically disordered proteins. Angewandte Chemie-International Edition 45 (42), S. 7012 - 7015 (2006)
241.
Zeitschriftenartikel
Zweckstetter, M.: Prediction of charge-induced molecular alignment: Residual dipolar couplings at pH 3 and alignment in surfactant liquid crystalline phases. European Biophysics Journal 35 (2), S. 170 - 180 (2006)
242.
Zeitschriftenartikel
Bertoncini, C. W.; Fernandez, C. O.; Griesinger, C.; Jovin, T. M.; Zweckstetter, M.: Familial mutants of α-synuclein with increased neurotoxicity have a destabilized conformation. Journal of Biological Chemistry 280, S. 30649 - 30652 (2005)
243.
Zeitschriftenartikel
Schnell, J. R.; Zhou, G. P.; Zweckstetter, M.; Rigby, A. C.; Chou, J. J.: Rapid and accurate structure determination of coiled-coil domains using NMR dipolar couplings: Application to cGMP-dependent protein kinase I alpha. Protein Science 14 (9), S. 2421 - 2428 (2005)
244.
Zeitschriftenartikel
Zweckstetter, M.; Schnell, J. R.; Chou, J. J.: Determination of the packing mode of the coiled-coil domain of cGMP-dependent protein kinase I alpha in solution using charge-predicted dipolar couplings. Journal of the American Chemical Society 127 (34), S. 11918 - 11919 (2005)
245.
Zeitschriftenartikel
Mukrasch, M.; Biernat, J.; von Bergen, M.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Sites of tau important for aggregation populate beta-structure and bind to microtubules and polyanions. Journal of Biological Chemistry 280 (26), S. 24978 - 24986 (2005)
246.
Zeitschriftenartikel
Bayrhuber, M.; Vijayan, V.; Ferber, M.; Graf, R.; Korukottu, J.; Imperial, J.; Garrett, J. E.; Olivera, B. M.; Terlau, H.; Zweckstetter, M. et al.; Becker, S.: Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family - Structural and functional characterization. Journal of Biological Chemistry 280 (25), S. 23766 - 23770 (2005)
247.
Zeitschriftenartikel
Vijayan, V.; Zweckstetter, M.: Simultaneous measurement of protein one-bond residual dipolar couplings without increased resonance overlap. Journal of Magnetic Resonance 174 (2), S. 245 - 253 (2005)
248.
Zeitschriftenartikel
Kneuper, H.; Janausch, I. G.; Vijayan, V.; Zweckstetter, M.; Bock, V.; Griesinger, C.; Unden, G.: The nature of the stimulus and of the fumarate binding site of the fumarate sensor DcuS of Escherichia coli. Journal of Biological Chemistry 280 (21), S. 20596 - 20603 (2005)
249.
Zeitschriftenartikel
Rumpel, S.; Kim, H. Y.; Vijayan, V.; Becker, S.; Zweckstetter, M.: Letter to the editor: Backbone resonance assignment of the homodimeric, 35 kDa chaperone CesT from enteropathogenic Escherichia coli. Journal of Biomolecular NMR 31 (4), S. 377 - 378 (2005)
250.
Zeitschriftenartikel
Rasia, R. M.; Bertoncini, C. W.; Marsh, D.; Hoyer, W.; Cherny, D. I.; Zweckstetter, M.; Griesinger, C.; Jovin, T. M.; Fernandez, C. O.: Structural characterization of copper(II) binding to α-Synuclein: Insights into the bioinorganic chemistry of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 102, 10.1073/pnas.0407881102, S. 4294 - 4299 (2005)
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