Zeitschriftenartikel (294)

201.
Zeitschriftenartikel
Balija, M. B. G.; Griesinger, C.; Herzig, A.; Zweckstetter, M.; Jäckle, H.: Pre-fibrillar alpha-Synuclein mutants cause Parkinson's disease-like non-motor symptoms in Drosophila. PLoS One 6 (9), e24701 (2011)
202.
Zeitschriftenartikel
Rezaei-Ghaleh, N.; Giller, K.; Becker, S.; Zweckstetter, M.: Effect of zinc binding on beta-amyloid structure and dynamics: Implications for a beta aggregation. Biophysical Journal 101 (5), S. 1202 - 1211 (2011)
203.
Zeitschriftenartikel
Luo, L.; Hannemann, M.; Koenig, S.; Hegermann, J.; Ailion, M.; Cho, M. K.; Sasidharan, N.; Zweckstetter, M.; Rensing, S. A.; Eimer, S.: The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology. Molecular Biology of the Cell 22 (14), S. 2564 - 2578 (2011)
204.
Zeitschriftenartikel
Krumova, P.; Meulmeester, E.; Garrido, M.; Tirard, M.; Hsiao, H. H.; Bossis, G.; Urlaub, H.; Zweckstetter, M.; Kuegler, S.; Melchior, F. et al.; Baehr, M.; Weishaupt, J. H.: Sumoylation inhibits alpha-synuclein aggregation and toxicity. Journal of Cell Biology 194 (1), S. 49 - 60 (2011)
205.
Zeitschriftenartikel
Kumar, S.; Rezaei-Ghaleh, N.; Terwel, D.; Thal, D. R.; Richard, M.; Hoch, M.; McDonald, J. M.; Wuellner, U.; Glebov, K.; Heneka, M. T. et al.; Walsh, D. M.; Zweckstetter, M.; Walter, J.: Extracellular phosphorylation of the amyloid beta-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO Journal 30 (11), S. 2255 - 2265 (2011)
206.
Zeitschriftenartikel
Rezaei-Ghaleh, N.; Andreetto, E.; Yan, L. M.; Kapurniotu, A.; Zweckstetter, M.: Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide. PLoS One 6 (5), e20289 (2011)
207.
Zeitschriftenartikel
Cho, M. K.; Kim, H. Y.; Fernandez, C. O.; Becker, S.; Zweckstetter, M.: Conserved core of amyloid fibrils of wild type and A30P mutant alpha-synuclein. Protein Science 20 (2), S. 387 - 395 (2011)
208.
Zeitschriftenartikel
Binolfi, A.; Valiente-Gabioud, A. A.; Duran, R.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Exploring the structural details of Cu(I) binding to alpha-synuclein by NMR spectroscopy. Journal of the American Chemical Society 133 (2), S. 194 - 196 (2011)
209.
Zeitschriftenartikel
Bibow, S.; Mukrasch, M. D.; Chinnathambi, S.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: The dynamic structure of filamentous tau. Angewandte Chemie-International Edition 50 (48), S. 11520 - 11524 (2011)
210.
Zeitschriftenartikel
Gruene, T.; Cho, M. K.; Karyagina, I.; Kim, H. Y.; Grosse, C.; Giller, K.; Zweckstetter, M.; Becker, S.: Integrated analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy. Journal of Biomolecular NMR 49 (2), S. 111 - 119 (2011)
211.
Zeitschriftenartikel
Villinger, S.; Briones, R.; Giller, K.; Zachariä, U.; Lange, A.; de Groot, B. L.; Griesinger, C.; Becker, S.; Zweckstetter, M.: Functional dynamics in the voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 107 (52), S. 22546 - 22551 (2010)
212.
Zeitschriftenartikel
Binolfi, A.; Rodriguez, E. E.; Valensin, D.; D'Amelio, N.; Ippoliti, E.; Obal, G.; Duran, R.; Magistrato, A.; Pritsch, O.; Zweckstetter, M. et al.; Valensin, G.; Carloni, P.; Quintanar, L.; Griesinger, C.; Fernandez, C. O.: Bioinorganic chemistry of Parkinson's disease: Structural determinants for the copper-mediated amyloid formation of Alpha-Synuclein. Inorganic Chemistry 49 (22), S. 10668 - 10679 (2010)
213.
Zeitschriftenartikel
de la Cruz, L.; Bajaj, R.; Becker, S.; Zweckstetter, M.: The intermembrane space domain of Tim23 is intrinsically disordered with a distinct binding region for presequences. Protein Science 19 (11), S. 2045 - 2054 (2010)
214.
Zeitschriftenartikel
Skora, L.; Becker, S.; Zweckstetter, M.: Characterization of amyloid fibrils of human beta-2-microglobulin by high-resolution magic-angle spinning NMR. ChemBioChem 11 (13), S. 1829 - 1832 (2010)
215.
Zeitschriftenartikel
Narayanan, R.L.; Dürr, U. H. N.; Bibow, S.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Automatic assignment of the intrinsically disordered protein Tau with 441-residues. Journal of the American Chemical Society 132 (34), S. 11906 - 11907 (2010)
216.
Zeitschriftenartikel
Ouertatani-Sakouhi, H.; El-Turk, F.; Fauvet, B.; Cho, M. K.; Karpinar, D. P.; Le Roy, D.; Dewor, M.; Roger, T.; Bernhagen, J.; Calandra, T. et al.; Zweckstetter, M.; Lashuel, H. A.: Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action. Journal of Biological Chemistry 285 (34), S. 26581 - 26598 (2010)
217.
Zeitschriftenartikel
Shoshan-Barmatz, V.; De Pinto, V.; Zweckstetter, M.; Raviv, Z.; Keinan, N.; Arbel, N.: VDAC, a multi-functional mitochondrial protein regulating cell life and death. Molecular Aspects of Medicine 31 (3), S. 227 - 285 (2010)
218.
Zeitschriftenartikel
Di Giovanni, S.; Eleuteri, S.; Paleologou, K. E.; Yin, G.; Zweckstetter, M.; Carrupt, P. A.; Lashuel, H. A.: Entacapone and Tolcapone, two catechol-O-methyltransferase inhibitors (ICOMT), block fibril formation of {alpha}-synuclein and {beta}-amyloid and protect against amyloid-induced toxicity. Journal of Biological Chemistry 285 (20), S. 14941 - 14954 (2010)
219.
Zeitschriftenartikel
Paleologou, K. E.; Oueslati, A.; Shakked, G.; Rospigliosi, C. C.; Kim, H. Y.; Lamberto, G. R.; Fernandez, C. O.; Schmid, A.; Chegini, F.; Gai, W. P. et al.; Chiappe, D.; Moniatte, M.; Schneider, B. L.; Aebischer, P.; Eliezer, D.; Zweckstetter, M.; Masliah, E.; Lashuel, H. A.: Phosphorylation at S87 is enhanced in synucleinopathies, inhibits α-synuclein oligomerization and influences synuclein-membrane interactions. Journal of Neuroscience 30 (9), S. 3184 - 3198 (2010)
220.
Zeitschriftenartikel
Schneider, R.; Etzkorn, M.; Giller, K.; Daebel, V.; Eisfeld, J.; Zweckstetter, M.; Griesinger, C.; Becker, S.; Lange, A.: The native conformation of the human VDAC1 N terminus. Angewandte Chemie - International Edition 49 (10), S. 1882 - 1885 (2010)
221.
Zeitschriftenartikel
Mbefo, M. K.; Paleologou, K. E.; Boucharaba, A.; Oueslati, A.; Schell, H.; Fournier, M.; Olschewski, D.; Yin, G.; Zweckstetter, M.; Masliah, E. et al.; Kahle, P. J.; Hirling, H.; Lashuel, H. A.: Phosphorylation of synucleins by members of the polo-like kinase family. Journal of Biological Chemistry 285 (4), S. 2807 - 2822 (2010)
222.
Zeitschriftenartikel
Salmon, L.; Nodet, G.; Oezenne, V.; Yin, G.; Jensen, M. R.; Zweckstetter, M.; Blackledge, M.: NMR characterization of long-range order in intrinsically disordered proteins. Journal of the American Chemical Society 132 (24), S. 8407 - 8418 (2010)
223.
Zeitschriftenartikel
Skora, L.; Becker, S.; Zweckstetter, M.: Molten globule precursor states are conformationally correlated to amyloid fibrils of human β-2-microglobulin. Journal of the American Chemical Society 132 (27), S. 9223 - 9225 (2010)
224.
Zeitschriftenartikel
Lamberto, G. R.; Binolfi, A.; Orcelett, M. L.; Bertoncini, C. O.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation. Proceedings of the National Academy of Sciences of the United States of America 106 (50), S. 21057 - 21062 (2009)
225.
Zeitschriftenartikel
Kim, H. Y.; Cho, M. K.; Kumar, A.; Maier, E.; Siebenhaar, C.; Becker, S.; Fernandez, C. O.; Lashuel, H. A.; Benz, R.; Lange, A. et al.; Zweckstetter, M.: Structural properties of pore-forming oligomers of α-synuclein. Journal of the American Chemical Society 131 (47), S. 17482 - 17489 (2009)
226.
Zeitschriftenartikel
Fischer, D.; Mukrasch, M. D.; Biernat, J.; Bibow, S.; Blackledge, M.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Conformational changes specific for pseudophosphorylation at Ser262 selectively impair binding of tau to microtubules. Biochemistry 48 (42), S. 10047 - 10055 (2009)
227.
Zeitschriftenartikel
Jensen, M. R.; Markwick, P. R.; Meier, S.; Griesinger, C.; Zweckstetter, M.; Grzesiek, S.; Bernado, P.; Blackledge, M.: Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure 17 (9), S. 1169 - 1185 (2009)
228.
Zeitschriftenartikel
Ouertatani-Sakouhi, H.; El-Turk, F.; Fauvet, B.; Roger, T.; Le Roy, D.; Karpinar, P.; Leng, L.; Bucala, R.; Zweckstetter, M.; Calandra, T. et al.; Lashuel, H. A.: A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor. Biochemistry 48 (41), S. 9858 - 9870 (2009)
229.
Zeitschriftenartikel
Cho, M. K.; Nodet, G.; Kim, H. K.; Jensen, M. R.; Bernado, P.; Fernandez, C. O.; Becker, S.; Blackledge, M.; Zweckstetter, M.: Structural characterization of α-synuclein in an aggregation prone state. Protein Science 18 (9), S. 1840 - 1846 (2009)
230.
Zeitschriftenartikel
Karpinar, P.; Gajula Balija, M. B.; Kügler, S.; Opazo, F.; Rezaei-Ghaleh, N.; Wender, N.; Kim, H. Y.; Taschenberger, G.; Falkenburger, B. H.; Heise, H. et al.; Kumar, A.; Riedel, D.; Fichtner, L.; Voigt, A.; Braus, G. H.; Giller, K.; Becker, S.; Herzig, A.; Baldus, M.; Jäckle, H.; Eimer, S.; Schulz, J. B.; Griesinger, C.; Zweckstetter, M.: Pre-fibrillar α-synuclein variants with impaired bold β-structure increase neurotoxicity in Parkinson's disease models. EMBO Journal 28 (20), S. 3256 - 3268 (2009)
231.
Zeitschriftenartikel
Mukrasch, M.; Bibow, S.; Korukottu, J.; Jeganathan, S.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Structural polymorphism of 441-residue tau at single residue resolution. PLoS Biology 7 (2), e1000034 (2009)
232.
Zeitschriftenartikel
Rezaei-Ghaleh, N.; Zweckstetter, M.; Morshedi, D.; Ebrahim-Habibi, A.; Nehmat-Gorgani, M.: Amyloidogenic potential of α-chymotrypsin in different conformational states. Biopolymers 91 (1), S. 28 - 36 (2009)
233.
Zeitschriftenartikel
Coudevylle, N.; Montaville, P.; Leonov, M.; Zweckstetter, M.; Becker, S.: Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A. Journal of Biological Chemistry 283 (51), S. 35918 - 35928 (2008)
234.
Zeitschriftenartikel
Rumpel, S.; Lakshmi, R.; Becker, S.; Zweckstetter, M.: Assignment-free solution NMR method reveals CesT as an unswapped homodimer. Protein Science 17 (11), S. 2015 - 2019 (2008)
235.
Zeitschriftenartikel
Soragni, A.; Zambelli, B.; Mukrasch, M.; Biernat, J.; Jeganathan, S.; Griesinger, C.; Ciurli, S.; Mandelkow, E.; Zweckstetter, M.: Structural characterization of binding of Cu(II) to Tau protein. Biochemistry 47 (41), S. 10841 - 10851 (2008)
236.
Zeitschriftenartikel
Bayrhuber, M.; Meins, T.; Habeck, M.; Becker, S.; Giller, K.; Villinger, S.; Vonrhein, C.; Griesinger, C.; Zweckstetter, M.; Zeth, K.: Structure of the human voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 105 (40), S. 15370 - 15375 (2008)
237.
Zeitschriftenartikel
El-Turk, F.; Cascella, M.; Ouertatami-Sakonhi, H.; Lakshmi, R. N.; Leng, L.; Bucala, R.; Zweckstetter, M.; Rothlisberger, U.; Lashuel, H. A.: The conformational flexibility of the carboxy terminal residues 105−114 Is a key modulator of the catalytic activity and stability of macrophage migration inhibitory factor. Biochemistry 47 (40), S. 10740 - 10756 (2008)
238.
Zeitschriftenartikel
Binolfi, A.; Lamberto, G. R.; Duran, R.; Quintanar, L.; Bertoncini, C. W.; Souza, J. M.; Cervenansky, C.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Site-specific interactions of Cu(II) with α and β-synuclein: bridging the molecular gap between metal binding and aggregation. Journal of the American Chemical Society 130 (35), S. 11801 - 11812 (2008)
239.
Zeitschriftenartikel
Kim, H. Y.; Cho, M. K.; Riedel, D.; Fernandez, C. O.; Zweckstetter, M.: Dissociation of amyloid fibrils of α-synuclein in supercooled water. Angewandte Chemie International Edition 47 (27), S. 5046 - 5048 (2008)
240.
Zeitschriftenartikel
Korukottu, J.; Schneider, R.; Vijayan, V.; Lange, A.; Pongs, O.; Becker, S.; Baldus, M.; Zweckstetter, M.: High-resolution 3D structure determination of kaliotoxin by solid-state NMR spectroscopy. PLoS One 3 (6), e2359 (2008)
241.
Zeitschriftenartikel
Paleologou, K. E.; Schmid, A. W.; Rospigliosi, C. C.; Kim, H. Y.; Lamberto, G. R.; Fredenburg, R. A.; Lansbury, P. T.; Fernandez, C. O.; Eliezer, D.; Zweckstetter, M. et al.; Lashuel, H. A.: Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of α-synuclein. The Journal of Biological Chemistry 283, S. 16895 - 16905 (2008)
242.
Zeitschriftenartikel
Sevvana, M.; Vijayan, V.; Zweckstetter, M.; Reinelt, S.; Madden, D. R.; Herbst-Irmer, R.; Sheldrick, G. M.; Bott, M.; Griesinger, C.; Becker, S.: A ligand-induced switch in the periplasmic domain of sensor histidine kinase CitA. Journal of Molecular Biology 377 (2), S. 512 - 523 (2008)
243.
Zeitschriftenartikel
Zweckstetter, M.: NMR: prediction of molecular alignment from structure using the PALES software. Nature Protocols 3 (4), S. 679 - 690 (2008)
244.
Zeitschriftenartikel
Montaville, P.; Condevylle, N.; Radhakrishnan, A.; Leonov, A.; Zweckstetter, M.; Becker, S.: The PIP2 binding mode of the C2 domains of rabphilin-3A. Protein Science 17 (6), S. 1025 - 1034 (2008)
245.
Zeitschriftenartikel
Rumpel, S.; Becker, S.; Zweckstetter, M.: High-resolution structure determination of the CylR2 homodimer using paramagnetic relaxation enhancement and structure-based prediction of molecular alignment. Journal of Biomolecular NMR 40 (1), S. 1 - 13 (2008)
246.
Zeitschriftenartikel
Bertoncini, C. W.; Rasia, R. M.; Lamberto, G. R.; Binolfi, A.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation. Journal of Molecular Biology 372 (3), S. 708 - 722 (2007)
247.
Zeitschriftenartikel
Mukrasch, M.; von Bergen, M.; Biernat, J.; Fischer, D.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: The "jaws" of the tau-microtubule interaction. Journal of Biological Chemistry 282 (16), S. 12230 - 12239 (2007)
248.
Zeitschriftenartikel
Cho, M. K.; Kim, H. Y.; Bernado, P.; Fernandez, C. O.; Blackledge, M.; Zweckstetter, M.: Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau. Journal of the American Chemical Society 129 (11), S. 3032 - 3033 (2007)
249.
Zeitschriftenartikel
Fischer, D.; Mukrasch, M.; von Bergen, M.; Klos-Witkowska, A.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Structural and microtubule binding properties of tau mutants of frontotemporal dementias. Biochemistry 46 (10), S. 2574 - 2582 (2007)
250.
Zeitschriftenartikel
Montaville, P.; Schlicker, C.; Leonov, A.; Zweckstetter, M.; Sheldrick, G. M.; Becker, S.: The C2A-C2B linker defines the high affinity Ca2+ binding mode of rabphilin-3A. Journal of Biological Chemistry 282 (7), S. 5015 - 5025 (2007)
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