Zeitschriftenartikel (274)

151.
Zeitschriftenartikel
Buhl, T.; Braun, A.; Forkel, S.; Moebius, W.; van Werven, L.; Jahn, O.; Rezaei-Ghaleh, N.; Zweckstetter, M.; Mempel, M.; Schoen, M. P. et al.; Haennssle, H. A.: Internalization routes of cell-penetrating melanoma antigen peptides into human dendritic cells. Experimental Dermatology 23 (1), S. 20 - 26 (2014)
152.
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Schwalbe, M.; Biernat, J.; Bibow, S.; Ozenne, V.; Jensen, M. R.; Kadavath, H.; Blackledge, M.; Mandelkow, E.; Zweckstetter, M.: Phosphorylation of human Tau protein by microtubule affinity-regulating kinase 2. Biochemistry 52 (50), S. 9068 - 9079 (2013)
153.
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Xiang, S. Q.; Gapsys, V.; Kim, H. Y.; Bessonov, S.; Hsiao, H. H.; Möhlmann, S.; Klaukien, V.; Ficner, R.; Becker, S.; Urlaub, H. et al.; Lührmann, R.; de Groot, B.; Zweckstetter, M.: Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure 21 (12), S. 2162 - 2174 (2013)
154.
Zeitschriftenartikel
Rezaei-Ghaleh, N.; Klama, F.; Munari, F.; Zweckstetter, M.: Predicting the rotational tumbling of dynamic multidomain proteins and supramolecular complexes. Angewandte Chemie International Edition 52 (43), S. 11410 - 11414 (2013)
155.
Zeitschriftenartikel
Taschenberger, G.; Toloe, J.; Tereshchenko, J.; Akerboom, J.; Wales, P.; Benz, R.; Becker, S.; Outeiro, T. F.; Looger, L. L.; Bähr, M. et al.; Zweckstetter, M.; Kügler, S.: Beta-synuclein aggregates and induces neurodegeneration in dopaminergic neurons. Annals of Neurology 74 (1), S. 109 - 118 (2013)
156.
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Bouter, I.; Dittrich, K.; Wittnam, J. L.; Rezaei-Ghaleh, N.; Pillot, T.; Papot-Coutourier, S.; Lefebvre, T.; Sprenger, F.; Wirths, O.; Zweckstetter, M. et al.; Bayer, T. A.: N-truncated amyloid beta (A beta) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits. Acta Neuropathologica 126 (2), S. 189 - 205 (2013)
157.
Zeitschriftenartikel
Aggarwal, S.; Snaidero, N.; Pähler, G.; Frey, S.; Sanchez, P.; Zweckstetter, M.; Janshoff, A.; Schneider, A.; Weil, M. T.; Schaap, I. A. T. et al.; Görlich, D.; Simons, M.: Myelin membrane assembly is driven by a phase transition of myelin basic proteinsiInto a cohesive protein meshwork. PLoS Biology 11 (6), e1001577 (2013)
158.
Zeitschriftenartikel
Wagner, J.; Ryazanov, S.; Leonov, A.; Levin, J.; Shi, S.; Schmidt, F.; Prix, C.; Pan-Montojo, F.; Bertsch, U.; Mitteregger-Kretzschmar, G. et al.; Geissen, M.; Eiden, M.; Leidel, F.; Hirschberger, T.; Deeg, A. A.; Krauth, J.; Zinth, W.; Tavan, P.; Pilger, J.; Zweckstetter, M.; Frank, T.; Baehr, M.; Weishaupt, J. H.; Uhr, M.; Urlaub, H.; Teichmann, U.; Samwer, M.; Bötzel, K.; Groschup, M.; Kretzschmar, H.; Griesinger, C.; Giese, A.: Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathologica 125 (6), S. 795 - 813 (2013)
159.
Zeitschriftenartikel
Zweckstetter, M.: Conserved amyloid core structure of stop mutants of the human prion protein. Prion 7 (3), S. 193 - 197 (2013)
160.
Zeitschriftenartikel
Munari, F.; Rezaei-Ghaleh, N.; Xiang, S. Q.; Fischle, W.; Zweckstetter, M.: Structural plasticity in human heterochromatin protein 1 beta. PLoS One 8 (4), e60887 (2013)
161.
Zeitschriftenartikel
Jaremko, M.; Jaremko, L.; Kim, H. Y.; Cho, M. K.; Schwieters, C. D.; Giller, K.; Becker, S.; Zweckstetter, M.: Cold denaturation of a protein dimer monitored at atomic resolution. Nature Chemical Biology 9 (4), S. 264 - 270 (2013)
162.
Zeitschriftenartikel
Jinwal, U. K.; Akoury, E.; Abisambra, J. F.; O'Leary, J. C.; Thompson, A. D.; Blair, L. J.; Jin, Y.; Bacon, J.; Nordhues, B. A.; Cockman, M. et al.; Zhang, J.; Li, P.; Zhang, B.; Borysov, S.; Uversky, V. N.; Biernat, J.; Mandelkow, E.; Gestwicki, J. E.; Zweckstetter, M.; Dickey, C. A.: Imbalance of Hsp70 family variants fosters tau accumulation. FASEB Journal 27 (4), S. 1450 - 1459 (2013)
163.
Zeitschriftenartikel
Akoury, E.; Pickardt, M.; Gajda, M. J.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Mechanistic basis of phenothiazine-driven inhibition of Tau aggregation. Angewandte Chemie-International Edition 52 (12), S. 3511 - 3515 (2013)
164.
Zeitschriftenartikel
Xiang, S. Q.; Narayanan, R. L.; Becker, S.; Zweckstetter, M.: N-H spin-spin couplings: Probing hydrogen bonds in proteins. Angewandte Chemie-International Edition 52 (12), S. 3525 - 3528 (2013)
165.
Zeitschriftenartikel
Skora, L.; Fonseca, L.; Hofele, R. V.; Riedel, D.; Giller, K.; Watzlawik, J.; Schulz-Schaeffer, W. J.; Urlaub, H.; Becker, S.; Zweckstetter, M.: Burial of the polymorphic residue 129 in amyloid fibrils of prion stop mutants. Journal of Biological Chemistry 288 (5), S. 2994 - 3002 (2013)
166.
Zeitschriftenartikel
Akoury, E.; Gajda, M.; Pickhardt, M.; Biernat, J.; Pornsuwan, S.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: Inhibition of tau filament formation by conformational modulation. Journal of the American Chemical Society 135 (7), S. 2853 - 2862 (2013)
167.
Zeitschriftenartikel
Skora, L.; Zweckstetter, M.: Determination of amyloid core structure using chemical shifts. Protein Science 21 (12), S. 1948 - 1953 (2012)
168.
Zeitschriftenartikel
Kroth, H.; Ansaloni, A.; Varisco, Y.; Jan, A.; Sreenivasachary, N.; Rezaei-Ghaleh, N.; Giriens, V.; Lohmann, S.; López-Deber, M. P.; Adolfsson, O. et al.; Pihlgren, M.; Paganetti, P.; Froestl, W.; Nagel-Steger, L.; Willbold, D.; Schrader, T.; Zweckstetter, M.; Pfeifer, A.; Lashuel, H. A.; Muhs, A.: Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation. Journal of Biological Chemistry 287 (41), S. 34786 - 34800 (2012)
169.
Zeitschriftenartikel
Munari, F.; Soeroes, S.; Zenn, H. M.; Schomburg, A.; Kost, N.; Schröder, S.; Klingberg, R.; Rezaei-Ghaleh, N.; Stützer, A.; Gelato, K. A. et al.; Walla, P. J.; Becker, S.; Schwarzer, D.; Zimmermann, B.; Fischle, W.; Zweckstetter, M.: Methylation of K9 in histone H3 directs alternative modes of highly dynamic interaction of heterochromatin protein hHP1β with the nucleosome. Journal of Biological Chemistry 287 (40), S. 33756 - 33765 (2012)
170.
Zeitschriftenartikel
El-Turk, F.; Fauvet, B.; Ashrafi, A.; Ouertatani-Sakouhi, H.; Cho, M. K.; Neri, M.; Cascella, M.; Rothlisberger, U.; Pojer, F.; Zweckstetter, M. et al.; Lashuel, H.: Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: Leucine 46 hydrophobic pocket. PLoS One 7 (9), e0045024 (2012)
171.
Zeitschriftenartikel
Zachariae, U.; Schneider, R.; Briones, R.; Gattin, Z.; Demers, J. P.; Giller, K.; Maier, E.; Zweckstetter, M.; Griesinger, C.; Becker, S. et al.; Benz, R.; de Groot, B. L.; Lange, A.: Beta-barrel mobility underlies closure of the voltage-dependent anion channel. Structure 20 (9), S. 1540 - 1549 (2012)
172.
Zeitschriftenartikel
Cho, M. K.; Xiang , S.; Kim, H. Y.; Becker, S.; Zweckstetter, M.: Cold-induced changes in the protein ubiquitin. PLoS One 7 (6), e37270 (2012)
173.
Zeitschriftenartikel
Petroi, D.; Popova, B.; Taheri-Talesh, N.; Irniger, S.; Shapasandzadeh, H.; Zweckstetter, M.; Outeiro, T. F.; Braus, G. H.: Aggregate clearance of α-synuclein in Saccharomyces cerevisiae depends more on autophagosome and vacuole function than on the proteasome. Journal of Biological Chemistry 287 (33), S. 27567 - 27579 (2012)
174.
Zeitschriftenartikel
Rezaei-Ghaleh, N.; Blackledge, M.; Zweckstetter, M.: Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery. ChemBioChem 13 (7), S. 930 - 950 (2012)
175.
Zeitschriftenartikel
Taschenberger, G.; Garrido, M.; Tereshchenko, Y.; Baehr, M.; Zweckstetter, M.; Kuegler, S.: Aggregation of alpha Synuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons. Acta Neuropathologica 123 (5), S. 671 - 683 (2012)
176.
Zeitschriftenartikel
Berger, R.; Courtieu, J.; Gil, R. R.; Griesinger, C.; Köck, M.; Lesot, P.; Luy, B.; Merlet, D.; Navarro-Vazquez, A.; Reggelin, M. et al.; Reinscheid, U. M.; Thiele, C. M.; Zweckstetter, M.: Is enantiomer assignment possible by NMR spectroscopy using residual dipolar couplings from chiral nonracemic alignment media?—A critical assessment. Angewandte Chemie International Edition 51 (33), S. 8388 - 8391 (2012)
177.
Zeitschriftenartikel
Daebel, V.; Chinnathambi, S.; Biernat, J.; Schwalbe, M.; Habenstein, B.; Loquet, A.; Akoury, E.; Tepper, K.; Mueller, H.; Baldus, M. et al.; Griesinger, C.; Zweckstetter, M.; Mandelkow, E.; Vijayan, V.; Lange, A.: β-sheet core of Tau paired helical filaments revealed by solid-state NMR. Journal of the American Chemical Society 134 (34), S. 13982 - 13989 (2012)
178.
Zeitschriftenartikel
Ozenne, V.; Schneider, R.; Yao, M.; Huang, J.-R.; Salmon, L.; Zweckstetter, M.; Jensen, M. R.; Blackledge, M.: Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. Journal of the American Chemical Society 134 (36), S. 15138 - 15148 (2012)
179.
Zeitschriftenartikel
Bibow, S.; Ozenne, V.; Biernat, J.; Blackledge, M.; Mandelkow, E.; Zweckstetter, M.: Structural impact of proline-directed pseudophosphorylation at AT8, AT100, and PHF1 epitopes on 441-residue tau. Journal of the American Chemical Society 133 (40), S. 15842 - 15845 (2011)
180.
Zeitschriftenartikel
Lamberto, C. R.; Torres-Monserrat, V.; Bertoncini, C. W.; Salvatella, X.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Toward the discovery of effective polycyclic inhibitors of alpha-Synuclein amyloid assembly. Journal of Biological Chemistry 286 (37), S. 32036 - 32044 (2011)
181.
Zeitschriftenartikel
Balija, M. B. G.; Griesinger, C.; Herzig, A.; Zweckstetter, M.; Jäckle, H.: Pre-fibrillar alpha-Synuclein mutants cause Parkinson's disease-like non-motor symptoms in Drosophila. PLoS One 6 (9), e24701 (2011)
182.
Zeitschriftenartikel
Rezaei-Ghaleh, N.; Giller, K.; Becker, S.; Zweckstetter, M.: Effect of zinc binding on beta-amyloid structure and dynamics: Implications for a beta aggregation. Biophysical Journal 101 (5), S. 1202 - 1211 (2011)
183.
Zeitschriftenartikel
Luo, L.; Hannemann, M.; Koenig, S.; Hegermann, J.; Ailion, M.; Cho, M. K.; Sasidharan, N.; Zweckstetter, M.; Rensing, S. A.; Eimer, S.: The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology. Molecular Biology of the Cell 22 (14), S. 2564 - 2578 (2011)
184.
Zeitschriftenartikel
Krumova, P.; Meulmeester, E.; Garrido, M.; Tirard, M.; Hsiao, H. H.; Bossis, G.; Urlaub, H.; Zweckstetter, M.; Kuegler, S.; Melchior, F. et al.; Baehr, M.; Weishaupt, J. H.: Sumoylation inhibits alpha-synuclein aggregation and toxicity. Journal of Cell Biology 194 (1), S. 49 - 60 (2011)
185.
Zeitschriftenartikel
Kumar, S.; Rezaei-Ghaleh, N.; Terwel, D.; Thal, D. R.; Richard, M.; Hoch, M.; McDonald, J. M.; Wuellner, U.; Glebov, K.; Heneka, M. T. et al.; Walsh, D. M.; Zweckstetter, M.; Walter, J.: Extracellular phosphorylation of the amyloid beta-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO Journal 30 (11), S. 2255 - 2265 (2011)
186.
Zeitschriftenartikel
Rezaei-Ghaleh, N.; Andreetto, E.; Yan, L. M.; Kapurniotu, A.; Zweckstetter, M.: Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide. PLoS One 6 (5), e20289 (2011)
187.
Zeitschriftenartikel
Cho, M. K.; Kim, H. Y.; Fernandez, C. O.; Becker, S.; Zweckstetter, M.: Conserved core of amyloid fibrils of wild type and A30P mutant alpha-synuclein. Protein Science 20 (2), S. 387 - 395 (2011)
188.
Zeitschriftenartikel
Binolfi, A.; Valiente-Gabioud, A. A.; Duran, R.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Exploring the structural details of Cu(I) binding to alpha-synuclein by NMR spectroscopy. Journal of the American Chemical Society 133 (2), S. 194 - 196 (2011)
189.
Zeitschriftenartikel
Bibow, S.; Mukrasch, M. D.; Chinnathambi, S.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: The dynamic structure of filamentous tau. Angewandte Chemie-International Edition 50 (48), S. 11520 - 11524 (2011)
190.
Zeitschriftenartikel
Gruene, T.; Cho, M. K.; Karyagina, I.; Kim, H. Y.; Grosse, C.; Giller, K.; Zweckstetter, M.; Becker, S.: Integrated analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy. Journal of Biomolecular NMR 49 (2), S. 111 - 119 (2011)
191.
Zeitschriftenartikel
Villinger, S.; Briones, R.; Giller, K.; Zachariä, U.; Lange, A.; de Groot, B. L.; Griesinger, C.; Becker, S.; Zweckstetter, M.: Functional dynamics in the voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 107 (52), S. 22546 - 22551 (2010)
192.
Zeitschriftenartikel
Binolfi, A.; Rodriguez, E. E.; Valensin, D.; D'Amelio, N.; Ippoliti, E.; Obal, G.; Duran, R.; Magistrato, A.; Pritsch, O.; Zweckstetter, M. et al.; Valensin, G.; Carloni, P.; Quintanar, L.; Griesinger, C.; Fernandez, C. O.: Bioinorganic chemistry of Parkinson's disease: Structural determinants for the copper-mediated amyloid formation of Alpha-Synuclein. Inorganic Chemistry 49 (22), S. 10668 - 10679 (2010)
193.
Zeitschriftenartikel
de la Cruz, L.; Bajaj, R.; Becker, S.; Zweckstetter, M.: The intermembrane space domain of Tim23 is intrinsically disordered with a distinct binding region for presequences. Protein Science 19 (11), S. 2045 - 2054 (2010)
194.
Zeitschriftenartikel
Skora, L.; Becker, S.; Zweckstetter, M.: Characterization of amyloid fibrils of human beta-2-microglobulin by high-resolution magic-angle spinning NMR. ChemBioChem 11 (13), S. 1829 - 1832 (2010)
195.
Zeitschriftenartikel
Narayanan, R.L.; Dürr, U. H. N.; Bibow, S.; Biernat, J.; Mandelkow, E.; Zweckstetter, M.: Automatic assignment of the intrinsically disordered protein Tau with 441-residues. Journal of the American Chemical Society 132 (34), S. 11906 - 11907 (2010)
196.
Zeitschriftenartikel
Ouertatani-Sakouhi, H.; El-Turk, F.; Fauvet, B.; Cho, M. K.; Karpinar, D. P.; Le Roy, D.; Dewor, M.; Roger, T.; Bernhagen, J.; Calandra, T. et al.; Zweckstetter, M.; Lashuel, H. A.: Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action. Journal of Biological Chemistry 285 (34), S. 26581 - 26598 (2010)
197.
Zeitschriftenartikel
Shoshan-Barmatz, V.; De Pinto, V.; Zweckstetter, M.; Raviv, Z.; Keinan, N.; Arbel, N.: VDAC, a multi-functional mitochondrial protein regulating cell life and death. Molecular Aspects of Medicine 31 (3), S. 227 - 285 (2010)
198.
Zeitschriftenartikel
Di Giovanni, S.; Eleuteri, S.; Paleologou, K. E.; Yin, G.; Zweckstetter, M.; Carrupt, P. A.; Lashuel, H. A.: Entacapone and Tolcapone, two catechol-O-methyltransferase inhibitors (ICOMT), block fibril formation of {alpha}-synuclein and {beta}-amyloid and protect against amyloid-induced toxicity. Journal of Biological Chemistry 285 (20), S. 14941 - 14954 (2010)
199.
Zeitschriftenartikel
Paleologou, K. E.; Oueslati, A.; Shakked, G.; Rospigliosi, C. C.; Kim, H. Y.; Lamberto, G. R.; Fernandez, C. O.; Schmid, A.; Chegini, F.; Gai, W. P. et al.; Chiappe, D.; Moniatte, M.; Schneider, B. L.; Aebischer, P.; Eliezer, D.; Zweckstetter, M.; Masliah, E.; Lashuel, H. A.: Phosphorylation at S87 is enhanced in synucleinopathies, inhibits α-synuclein oligomerization and influences synuclein-membrane interactions. Journal of Neuroscience 30 (9), S. 3184 - 3198 (2010)
200.
Zeitschriftenartikel
Schneider, R.; Etzkorn, M.; Giller, K.; Daebel, V.; Eisfeld, J.; Zweckstetter, M.; Griesinger, C.; Becker, S.; Lange, A.: The native conformation of the human VDAC1 N terminus. Angewandte Chemie - International Edition 49 (10), S. 1882 - 1885 (2010)
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