Publications

2.

Journal Article

Zeppillo, T.; Ali, H.; Ravichandran, S.; Ritter, T. C.; Wenger, S.; López-Murcia, F. J.; Gideons, E.; Signorelli, J.; Schmeisser, M. J.; Wiltfang, J. et al.; Rhee, J. S.; Brose, N.; Taschenberger, H.; Krüger-Burg, D. D.: Functional Neuroligin-2-MDGA1 interactions differentially regulate synaptic GABA_ARs and cytosolic gephyrin aggregation. Communications Biology 7, 1157 (2024)

MPG.PuRe

pre-print

3.

Journal Article

Jeong, S.; Lee, B.-Y.; Rhee, J. S.; Lee, J.-H.: G protein β subunits regulate Ca_v3.3 T-type channel activity and current kinetics via interaction with the Casub_v3.3 C-terminus. Biochimica et Biophysica Acta: BBA 1866 (6), 184337 (2024)

MPG.PuRe

4.

Journal Article

Koppensteiner, P.; Bhandari, P.; Önal, C.; Borges-Merjane, C.; Le Monnier, E.; Roy, U.; Nakamura, Y.; Sadakata, T.; Sanbo, M.; Hirabayashi, M. et al.; Rhee, J. S.; Brose, N.; Jonas, P.; Shigemoto, R.: GABA_B receptors induce phasic release from medial habenula terminals through activity-dependent recruitment of release-ready vesicles. PNAS 121 (8), e2301449121 (2024)

MPG.PuRe

5.

Journal Article

Clavet-Fournier, V.; Lee, C.; Wegner, W.; Brose, N.; Rhee, J. S.; Willig, K. I.: Pre- and postsynaptic nanostructures increase in size and complexity after induction of long-term potentiation. iScience 27 (1), 108679 (2024)

MPG.PuRe

6.

Journal Article

Altas, B.; Rhee, H. J.; Ju, A.; Solis, H. C.; Karaca, S.; Winchenbach, J.; Kaplan-Arabaci, O.; Schwark, M.; Ambrozkiewicz, M.; Lee, C. et al.; Spieth, L.; Wieser, G. L.; Chaugule, V. K.; Majoul, I.; Hassan, M. A.; Goel, R.; Wojcik, S. M.; Koganezawa, N.; Hanamura, K.; Rotin, D.; Pichler, A.; Mitkovski, M.; de Hoz, L.; Poulopoulos, A.; Urlaub, H.; Jahn, O.; Saher, G.; Brose, N.; Rhee, J.; Kawabe, H.: Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity. Journal of Cell Biology 223 (1), e201902050 (2024)

MPG.PuRe

7.

Journal Article

Wittenmayer, N.; Petkova-Tuffy, A.; Borgmeyer, M.; Lee, C.; Becker, J.; Böning, A.; Kügler, S.; Rhee, J. S.; Viotti, J.S.; Dresbach, T.: S-SCAM is essential for synapse formation. Frontiers in Cellular Neuroscience 17, 1182493 (2023)

MPG.PuRe

8.

Journal Article

Rößler, N.; Jungenitz, T.; Sigler, A.; Bird, A.; Mittag, M.; Rhee, J. S.; Deller, T.; Cuntz, H.; Brose, N.; Schwarzacher, S. W. et al.; Jedlicka, P.: Skewed distribution of spines is independent of presynaptic transmitter release and synaptic plasticity, and emerges early during adult neurogenesis. Open Biology 13 (8), 230063 (2023)

MPG.PuRe

9.

Journal Article

Daniel, J. A.; Elizarova, S.; Shaib, A. H.; Chouaib, A. A.; Magnussen, H. M.; Wang, J.; Brose, N.; Rhee, J.; Tirard, M.: An intellectual-disability-associated mutation of the transcriptional regulator NACC1 impairs glutamatergic neurotransmission. Frontiers in Molecular Neuroscience 16, 1115880 (2023)

MPG.PuRe

10.

Journal Article

Banerjee, A.; Imig, C.; Balakrishnan, K.; Kershberg, L.; Lipstein, N.; Uronen, R.-K.; Wang, J.; Cai, X.; Benseler, F.; Rhee, J. S. et al.; Cooper, B. H.; Liu, C.; Wojcik, S. M.; Brose, N.; Kaeser, P. S.: Molecular and functional architecture of striatal dopamine release sites. Neuron 110 (2), pp. 248 - 265.e9 (2022)

MPG.PuRe

11.

Journal Article

Spieth, L.; Berghoff, S. A.; Stumpf, S. K.; Winchenbach, J.; Michaelis, T.; Watanabe, T.; Gerndt, N.; Düking, T.; Hofer, S.; Ruhwedel, T. et al.; Shaib, A. H.; Willig, K. I.; Kronenberg, K.; Karst, U.; Frahm, J.; Rhee, J. S.; Minguet, S.; Möbius, W.; Kruse, N.; von der Brelie, C.; Michels, P.; Stadelmann, C.; Hülper, P.; Saher, G.: Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport. Neuro-Oncology Advances 3 (1), vdab140 (2021)

MPG.PuRe

12.

Journal Article

Ambrozkiewicz, M.; Borisova, E.; Schwark, M.; Ripamonti, S.; Schaub, T.; Smorodchenko, A.; Weber, A. I.; Rhee, H. J.; Altas, B.; Yilmaz, R. et al.; Mueller, S.; Piepkorn, L.; Horan, S. T.; Straussberg, R.; Zaqout, S.; Jahn, O.; Dere, E.; Rosário, M.; Boehm-Sturm, P.; Borck, G.; Willig, K. I.; Rhee, J. S.; Tarabykin, V.; Kawabe, H.: The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc. Molecular Psychiatry 26, pp. 1980 - 1995 (2021)

MPG.PuRe

13.

Journal Article

Wagner, S.; Lee, C.; Rojas, L.; Specht, C. G.; Rhee, J. S.; Brose, N.; Papadopoulos, T.: The α3 subunit of GABA_A receptors promotes formation of inhibitory synapses in the absence of collybistin. Journal of Biological Chemistry 296, 100709 (2021)

MPG.PuRe

14.

Journal Article

Ripamonti, S.; Shomroni, O.; Rhee, J. S.; Chowdhury, K.; Jahn, O.; Hellmann, K. P.; Bonn, S.; Brose, N.; Tirard, M.: SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20. Journal of Neurochemistry 154 (6), pp. 647 - 661 (2020)

MPG.PuRe

15.

Journal Article

Ripamonti, S.; Shomroni, O.; Rhee, J.; Chowdhury, K.; Jahn, O.; Hellmann, K.; Bonn, S.; Brose, N.; Tirard, M.: SUMOylation controls the neurodevelopmental function of the transcription factor Zbtb20. Journal of Neurochemistry: official journal of the International Society for Neurochemistry 154 (6), pp. 647 - 661 (2020)

MPG.PuRe

16.

Journal Article

Maus, L.; Lee, C.; Altas, B.; Sertel, S. M.; Weyand, K.; Rizzoli, S. O.; Rhee, J. S.; Brose, N.; Imig, C.; Cooper, B. H.: Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses. Cell Reports 30 (11), pp. 3632 - 3643.e8 (2020)

MPG.PuRe

17.

Journal Article

Nestvogel, D. B.; Merino, R. M.; Leon-Pinzon, C.; Schottdorf, M.; Lee, C.; Imig, C.; Brose, N.; Rhee, J. S.: The Synaptic Vesicle Priming Protein CAPS-1 Shapes the Adaptation of Sensory Evoked Responses in Mouse Visual Cortex. Cell Reports 30 (10), pp. 3261 - 3269.e4 (2020)

MPG.PuRe

18.

Journal Article

Rhee, H. J.; Shaib, A. H.; Rehbach, K.; Lee, C.; Seif, P.; Thomas, C.; Gideons, E.; Guenther, A.; Krutenko, T.; Hebisch, M. et al.; Peitz, M.; Brose, N.; Brüstle, O.; Rhee, J.: An autaptic culture system for standardized analyses of iPSC-derived human neurons. Cell Reports 27 (7), pp. 2212 - 2228 (2019)

MPG.PuRe

19.

Journal Article

Repetto, D.; Brockhaus, J.; Rhee, H. J.; Lee, C.; Kilimann, M. W.; Rhee, J.; Northoff, L. M.; Guo, W.; Reissner, C.; Missler, M.: Molecular dissection of neurobeachin function at excitatory synapses. Frontiers in synaptic neuroscience, UNSP 28 (2018)

MPG.PuRe

20.

Journal Article

Ferreira, D. G.; Temido-Ferreira, M.; Miranda, H. V.; Batalha, V. L.; Coelho, J. E.; Szegö, É. M.; Marques-Morgado, I.; Vaz, S. H.; Rhee, J. S.; Schmitz, M. et al.; Zerr, I.; Lopes, L. V.; Outeiro, T. F.: Alpha-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B. Nature Neuroscience 20 (11), pp. 1569 - 1579 (2017)

MPG.PuRe

21.

Journal Article

Lai, Y.; Choi, U. B.; Leitz, J.; Rhee, H. J.; Lee, C.; Altas, B.; Zhao, M.; Pfuetzner, R. A.; Wang, A. L.; Brose, N. et al.; Rhee, J.; Brunger, A. T.: Molecular mechanisms of synaptic vesicle priming by Munc13 and Munc18. Neuron 95 (3), pp. 591 - 607.e10 (2017)

MPG.PuRe

22.

Journal Article

Sigler, A.; Oh, W. C.; Imig, C.; Altas, B.; Kawabe, H.; Cooper, B. H.; Kwon, H.-B.; Rhee, J.-S.; Brose, N.: Formation and maintenance of functional spines in the absence of presynaptic glutamate release. Neuron 94, pp. 304 - 311 (2017)

MPG.PuRe

23.

Journal Article

Kawabe, H.; Mitkovski, M.; Kaeser, P. S.; Hirrlinger, J.; Opazo, F.; Nestvogel, D.; Kalla, S.; Fejtova, A.; Verrier, S. E.; Bungers, S. R. et al.; Cooper, B. H.; Varoqueaux, F.; Wang, Y.; Nehring, R. B.; Gundelfinger, E. D.; Rosenmund, C.; Rizzoli, S. O.; Südhof, T. C.; Rhee, J.-S.; Brose, N.: ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones. The Journal of Cell Biology 216 (4), pp. 1143 - 1161 (2017)

MPG.PuRe

24.

Journal Article

Roh, J. D.; Choi, S.-Y.; Cho, Y. S.; Choi, T.-Y.; Park, J.-S.; Cutforth, T.; Chung, W.; Park, H.; Lee, D.; Kim, M.-H. et al.; Lee, Y.; Mo, S.; Rhee, J.-S.; Kim, H.; Ko, J.; Choi, S.-Y.; Bae, Y. C.; Shen, K.; Kim, E.; Han, K.: Increased excitatory synaptic transmission of dentate granule neurons in mice lacking PSD-95-interacting adhesion molecule Neph2/Kirrel3 during the early postnatal period. Frontiers in Molecular Neuroscience 10, 81 (2017)

MPG.PuRe

25.

Journal Article

Lipstein, N.; Verhoeven-Duif, N. M.; Michelassi, F. E.; Calloway, N.; van Hasselt, P. M.; Pienkowska, K.; van Haaften, G.; van Haelst, M. M.; van Empelen, R.; Cuppen, I. et al.; van Teeseling, H. C.; Evelein, A. M. V.; Vorstman, J. A.; Thoms, S.; Jahn, O.; Duran, K. J.; Monroe, G. R.; Ryan, T. A.; Taschenberger, H.; Dittman, J. S.; Rhee, J.; Visser, G.; Jans, J. J.; Brose, N.: Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder. The Journal of Clinical Investigation 127 (3), pp. 1005 - 1018 (2017)

MPG.PuRe

26.

Journal Article

Ripamonti, S.; Ambrozkiewicz, M.; Guzzi, F.; Gravati, M.; Biella, G.; Bormuth, I.; Hammer, M.; Tuffy, L.; Sigler, A.; Kawabe, H. et al.; Nishimori, K.; Toselli, M.; Brose, N.; Parenti, M.; Rhee, J.: Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. eLife 6, e22466 (2017)

MPG.PuRe

27.

Journal Article

Papadopoulos, T.; Rhee, H. J.; Subramanian, D.; Paraskevopoulou, F.; Mueller, R.; Schultz, C.; Brose, N.; Rhee, J.-S.; Betz, H.: Endosomal phosphatidylinositol 3-phosphate promotes gephyrin clustering and GABAergic neurotransmission at inhibitory postsynapses. The Journal of Biological Chemistry 292 (4), pp. 1160 - 1177 (2017)

MPG.PuRe

28.

Journal Article

Mortensen, L. S.; Park, S. J. H.; Ke, J.-b.; Cooper, B. H.; Zhang, L.; Imig, C.; Löwel, S.; Reim, K.; Brose, N.; Rhee, J.-S. et al.; Singer, J. H.: Complexin 3 increases the fidelity of signaling in a retinal circuit by regulating exocytosis at ribbon synapses. Cell Reports 15 (10), pp. 2239 - 2250 (2016)

MPG.PuRe

29.

Journal Article

Frank, J. A.; Yushchenko, D. A.; Hodson, D. J.; Lipstein, N.; Nagpal, J.; Rutter, G. A.; Rhee, J.-S.; Gottschalk, A.; Brose, N.; Schultz, C. et al.; Trauner, D.: Photoswitchable diacylglycerols enable optical control of protein kinase C. Nature Chemical Biology 12, pp. 755 - 762 (2016)

MPG.PuRe

30.

Journal Article

Jang, S.; Oh, D.; Lee, Y.; Hosy, E.; Shin, H.; van Riesen, C.; Whitcomb, D.; Warburton, J. M.; Jo, J.; Kim, D. et al.; Kim, S. G.; Um, S. M.; Kwon, S.-k.; Kim, M.-H.; Roh, J. D.; Woo, J.; Jun, H.; Lee, D.; Mah, W.; Kim, H.; Kaang, B.-K.; Cho, K.; Rhee, J.-S.; Choquet, D.; Kim, E.: Synaptic adhesion molecule IgSF11 regulates synaptic transmission and plasticity. Nature Neuroscience 19, pp. 84 - 93 (2016)

MPG.PuRe

31.

Journal Article

Hammer, M.; Krüger-Burg, D. D.; Tuffy, L.; Cooper, B. H.; Taschenberger, H.; Goswami, S. P.; Ehrenreich, H.; Jonas, P.; Varoqueaux, F.; Rhee, J. et al.; Brose, N.: Perturbed hippocampal synaptic inhibition and γ-oscillations in a neuroligin-4 knockout mouse model of autism. Cell Reports 13 (3), pp. 516 - 523 (2015)

MPG.PuRe

32.

Journal Article

Nawaz, S.; Sánchez, P.; Schmitt, S.; Snaidero, N.; Mitkovski, M.; Velte, C.; Brückner, B. R.; Alexopoulos, I. K.; Czopka, T.; Jung, S. et al.; Rhee, J.; Janshoff, A.; Witke, W.; Schaap, I. A. T.; Lyons, D. A.; Simons, M.: Actin filament turnover drives leading edge growth during myelin sheath formation in the central nervous system. Developmental Cell 34 (2), pp. 139 - 151 (2015)

MPG.PuRe

33.

Journal Article

Vogl, C.; Cooper, B. H.; Neef, J.; Wojcik, S. M.; Reim, K.; Reisinger, E.; Brose, N.; Rhee, J.-S.; Moser, T.; Wichmann, C.: Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells. Journal of Cell Science 128 (4), pp. 638 - 644 (2015)

MPG.PuRe

34.

Journal Article

Nguyen Truong, C. Q.; Nestvogel, D.; Ratai, O.; Schirra, C.; Stevens, D. R.; Brose, N.; Rhee, J.; Rettig, J.: Secretory vesicle priming by CAPS is independent of the SNARE-bind MUN domain. Cell Reports 9 (3), pp. 902 - 909 (2014)

MPG.PuRe

35.

Journal Article

Imig, C.; Min, S.-W.; Krinner, S.; Arancillo, M.; Rosenmund, C.; Südhof, T. C.; Rhee, J.; Brose, N.; Cooper, B. H.: The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones. Neuron 84 (2), pp. 416 - 431 (2014)

MPG.PuRe

36.

Journal Article

Hsia, H.-E.; Kumar, R.; Luca, R.; Takeda, M.; Courchet, J.; Nakashima, J.; Wu, S.; Goebbels, S.; An, W.; Eickholt, B. J. et al.; Polleux, F.; Rotin, D.; Wu, H.; Rossner, M. J.; Bagni, C.; Rhee, J.-S.; Brose, N.; Kawabe, H.: Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth. Proceedings of the National Academy of Sciences of the United States of America 111 (36), pp. 13205 - 13210 (2014)

MPG.PuRe

37.

Journal Article

Mayer, S.; Kumar, R.; Jaiswal, M.; Soykan, T.; Ahmadian, M. R.; Brose, N.; Betz, H.; Rhee, J.-S.; Papadopoulos, T.: Collybistin activation by GTP-TC10 enhances postsynaptic gephyrin clustering and hippocampal GABAergic neurotransmission. PNAS 110 (51), pp. 20795 - 20800 (2013)

MPG.PuRe

38.

Journal Article

Lipstein, N.; Sakaba, T.; Cooper, B. H.; Lin, K.-H.; Strenzke, N.; Ashery, U.; Rhee, J.-S.; Taschenberger, H.; Neher, E.; Brose, N.: Dynamic Control of Synaptic Vesicle Replenishment and Short-Term Plasticity by Ca²⁺-Calmodulin-Munc13-1 Signaling. Neuron 79 (1), pp. 82 - 96 (2013)

MPG.PuRe

39.

Journal Article

Nair, R.; Lauks, J.; Jung, S.; Cooke, N. E.; de Wit, H.; Brose, N.; Kilimann, M. W.; Verhage, M.; Rhee, J.: Neurobeachin regulates neurotransmitter receptor trafficking to synapses. Journal of Cell Biology 200 (1), pp. 61 - 80 (2013)

MPG.PuRe

40.

Journal Article

Lipstein, N.; Schaks, S.; Dimova, K.; Kalkhof, S.; Ihling, C.; Kölbel, K.; Ashery, U.; Rhee, J.; Brose, N.; Sinz, A. et al.; Jahn, O.: Nonconserved Ca²⁺/Calmodulin Binding Sites in Munc13s Differentially Control Synaptic Short-Term Plasticity. Molecular and Cellular Biology 32 (22), pp. 4628 - 4641 (2012)

MPG.PuRe

41.

Journal Article

Fünfschilling, U.; Jockusch, W. J.; Sivakumar, N.; Möbius, W.; Corthals, K.; Li, S.; Quintes, S.; Kim, Y.; Schaap, I. A. T.; Rhee, J.-S. et al.; Nave, K.-A.; Saher, G.: Critical time window of neuronal cholesterol synthesis during neurite outgrowth. The Journal of Neuroscience 32 (22), pp. 7632 - 7645 (2012)

MPG.PuRe

42.

Journal Article

Burgalossi, A.; Jung, S.; Man, K.-n. M.; Nair, R.; Jockusch, W. J.; Wojcik, S. M.; Brose, N.; Rhee, J.-S.: Analysis of neurotransmitter release mechanisms by photolysis of caged Ca²⁺ in an autaptic neuron culture system. Nature Protocols 7 (7), pp. 1351 - 1365 (2012)

MPG.PuRe

43.

Journal Article

Herzog, E.; Nadrigny, F.; Silm, K.; Biesemann, C.; Helling, I.; Bersot, T.; Steffens, H.; Schwartzmann, R.; Nägerl, U. V.; El Mestikawy, S. et al.; Rhee, J.; Kirchhoff, F.; Brose, N.: In vivo imaging of intersynaptic vesicle exchange using VGLUT1venus knock-in mice. The Journal of Neuroscience 31 (43), pp. 15544 - 15559 (2011)

MPG.PuRe

44.

Journal Article

Reisinger, E.; Bresee, C.; Neef, J.; Nair, R.; Reuter, K.; Bulankina, A.; Nouvian, R.; Koch, M.; Bückers, J.; Kastrup, L. et al.; Roux, I.; Petit, C.; Hell, S. W.; Brose, N.; Rhee, J.-S.; Kügler, S.; Brigande, J. V.; Moser, T.: Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis. The Journal of Neuroscience 31 (13), pp. 4886 - 4895 (2011)

MPG.PuRe

45.

Journal Article

Yang, J.; Seo, J.; Nair, R.; Han, S.; Jang, S.; Kim, K.; Han, K.; Paik, S. K.; Choi, J.; Lee, S. et al.; Bae, Y. C.; Topham, M. K.; Prescott, S. M.; Rhee, J.-S.; Choi, S.-Y.; Kim, E.: DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO Journal 30 (1), pp. 165 - 180 (2011)

MPG.PuRe

46.

Journal Article

Burgalossi, A.; Jung, S.; Meyer, G.; Jockusch, W. J.; Jahn, O.; Taschenberger, H.; O'Connor, V. M.; Nishiki, T.-i.; Takahashi, M.; Brose, N. et al.; Rhee, J.-S.: SNARE Protein Recycling by αSNAP and βSNAP Supports Synaptic Vesicle Priming. Neuron 68 (3), pp. 473 - 487 (2010)

MPG.PuRe

47.

Journal Article

Burgalossi, A.; Jung, S.; Meyer, G.; Jockusch, W. J.; Jahn, O.; Taschenberger, H.; O'Connor, V. M.; Nishiki, T.-i.; Takahashi, M.; Brose, N. et al.; Rhee, J. S.: SNARE Protein Recycling by αSNAP and βSNAP Supports Synaptic Vesicle Priming. Neuron 68 (3), pp. 473 - 487 (2010)

MPG.PuRe

48.

Journal Article

Liu, Y.; Schirra, C.; Edelmann, L.; Matti, U.; Rhee, J.; Hof, D.; Bruns, D.; Brose, N.; Rieger, H.; Stevens, D. R. et al.; Rettig, J.: Two distinct secretory vesicle-priming steps in adrenal chromaffin cells. Journal of Cell Biology 190 (6), pp. 1067 - 1077 (2010)

MPG.PuRe

49.

Journal Article

Hsu, C.; Morohashi, Y.; Yoshimura, S.-i.; Manrique-Hoyos, N.; Jung, S.; Lauterbach, M. A.; Bakhti, M.; Grønborg, M.; Möbius, W.; Rhee, J. et al.; Barr, F. A.; Simons, M.: Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C. Journal of Cell Biology 189 (2), pp. 223 - 232 (2010)

MPG.PuRe

50.

Journal Article

Shin, O.-H.; Lu, J.; Rhee, J.-S.; Tomchick, D. R.; Pang, Z. P.; Wojcik, S. M.; Camacho-Perez, M.; Brose, N.; Machius, M.; Rizo, J. et al.; Rosenmund, C.; Südhof, T. C.: Munc13 C₂B domain is an activity-dependent Ca²⁺ regulator of synaptic exocytosis. Nature Structural & Molecular Biology 17 (3), pp. 280 - 288 (2010)

MPG.PuRe