Max Planck Institute for Multidisciplinary Sciences

Publications

Journal Article (110)

1.

Journal Article

Napp, J.; Siebel, P.; Rausch, H.; Kuchta, K.; Efferth, T.; Alves, F.; Ellenrieder, V.; Cameron, S.: Prolonged survival by combination treatment with a standardized herbal extract from Japanese Kampo-medicine (Juzentaihoto) and gemcitabine in an orthotopic transplantation pancreatic cancer model. Frontiers in Oncology 14, 1454291 (2024)

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Notter, S.; Choezom, D.; Griebel, T.; Ramos Gomes, F.; Möbius, W.; De Oliveira, T.; Conradi, L.-C.; Alves, F.; Feldmann, C.: High-Load Core@Shell Nanocarriers with Irinotecan and 5-Fluorouracil for Combination Chemotherapy in Colorectal Cancer. Small science 4 (11), 2400196 (2024)

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Tan, L.; Zschüntzsch, J.; Meyer, S.; Stobbe, A.; Bruex, H.; Regensburger, A. P.; Claßen, M.; Alves, F.; Jüngert, J.; Rother, U. et al.; Li, Y.; Danko, V.; Lang, W.; Türk, M.; Schmidt, S.; Vorgerd, M.; Schlaffke, L.; Woelfle, J.; Hahn, A.; Mensch, A.; Winterholler, M.; Trollmann, R.; Heiß, R.; Wagner, A. L.; Raming, R.; Knieling, F.: Non-invasive optoacoustic imaging of glycogen-storage and muscle degeneration in late-onset Pompe disease. Nature Communications 15, 7843 (2024)

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4.

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Agorku, D. J.; Bosio, A.; Alves, F.; Ströbel, P.; Hardt, O.: Colorectal cancer-associated fibroblasts inhibit effector T cells via NECTIN2 signaling. Cancer Letters 595, 216985 (2024)

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5.

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Kulkarni, A.; Ferreira, N.; Scodellaro, R.; Choezom, D.; Alves, F.: A Curated Cell Life Imaging Dataset of Immune-enriched Pancreatic Cancer Organoids with Pre-trained AI Models. Scientific Data 11, 820 (2024)

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6.

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Sabljo, K.; Ischyropoulou, M.; Napp, J.; Alves, F.; Feldmann, C.: High-load nanoparticles with a chemotherapeutic SN-38/FdUMP drug cocktail. Nanoscale 16, pp. 14853 - 14860 (2024)

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7.

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Ferrari, D. P.; Ramos Gomes, F.; Alves, F.; Markus, M. A.: KPC-luciferase-expressing cells elicit an anti-tumor immune response in a mouse model of pancreatic cancer. Scientific Reports 14, 13602 (2024)

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8.

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Ferreira, N.; Kulkarni, A.; Agorku, D.; Midelashvili, T.; Hardt, O.; Legler, T. J.; Ströbel, P.; Conradi, L.-C.; Alves, F.; Ramos Gomes, F. et al.; Markus, M. A.: OrganoIDNet: a deep learning tool for identification of therapeutic effects in PDAC organoid-PBMC co-cultures from time-resolved imaging data. Cellular Oncology (2024)

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9.

Journal Article

Arora, B.; Kulkarni, A.; Markus, M. A.; Ströbel, P.; Bohnenberger, H.; Alves, F.; Ramos-Gomes, F.: Label-free quantification of imaging features in the extracellular matrix of left and right-sided colon cancer tissues. Scientific Reports 14, 7510 (2024)

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10.

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Dullin, C.; Albers , J.; Tagat, A.; Lorenzon, A.; D'Amico, L.; Chiriotti, S.; Sodini, N.; Dreossi, D.; Alves, F.; Bergamaschi, A. et al.; Tromba, G.: In vivo low-dose phase-contrast CT for quantification of functional and anatomical alterations in lungs of an experimental allergic airway disease mouse model. Frontiers in medicine 11, 1338846 (2024)

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11.

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D'Amico, L.; Svetlove, A.; Longo, E.; Meyer, R.; Senigagliesi, B.; Saccomano, G.; Nolte, P.; Wagner, W. L.; Wielpuetz, M. O.; Leitz, D. H. W. et al.; Duerr, J.; Mall, M. A.; Casalis, L.; Köster, S.; Alves, F.; Tromba, G.; Dullin, C.: Characterization of transient and progressive pulmonary fibrosis by spatially correlated phase contrast microCT, classical histopathology and atomic force microscopy. Computers in Biology and Medicine 169, 107947 (2024)

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Luna, O. F.; Perez, Y. V.; Ferrari, D. P.; Sayedipour, S. S.; Royo, M.; Acosta, G. A.; Cruz, L. J.; Alves, F.; Agner, E.; Sydnes, M. O. et al.; Albericio, F.: Impact of N-Terminal PEGylation on Synthesis and Purification of Peptide-Based Cancer Epitopes for Pancreatic Ductal Adenocarcinoma (PDAC). ACS Omega 9 (32), pp. 34544 - 34554 (2024)

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13.

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Rudolph, D.; Ischyropoulou, M.; Pfeifer, J.; Napp, J.; Schepers, U.; Alves, F.; Feldmann, C.: Cocktail of lipophilic and hydrophilic chemotherapeutics in high-load core@shell nanocarriers to treat pancreatic tumours. Nanoscale Advances 6, pp. 973 - 984 (2024)

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14.

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Sagar, M. M. R.; Svetlove, A.; D’Amico, L.; Pinkert-Leetsch, D.; Missbach-Guentner, J.; Longo, E.; Tromba, G.; Bohnenberger, H.; Alves, F.; Dullin, C.: Optical clearing: an alternative sample preparation method for propagation based phase contrast μCT. Frontiers in Physics 12, 1433895 (2024)

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15.

Journal Article

Cobanoglu, O.; Delval, L.; Ferrari, D. P.; Deruyter, L.; Heumel, S.; Wolowczuk, I.; Hussein, A.; Menevse, A. N.; Bernard, D.; Beckhove, P. et al.; Alves, F.; Trottein, F.: Depletion of preexisting B-cell lymphoma 2-expressing senescent cells before vaccination impacts antigen-specific antitumor immune responses in old mice. Aging Cell 22 (12), e14007 (2023)

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16.

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Garnier, N.; Berghout, J.; Zygmunt, A.; Singh, D.; Huang, K. A.; Kantz, W.; Blankart, C. R.; Gillner, S.; Zhao, J.; Roettger, R. et al.; Saier, C.; Kirschner, J.; Schenk, J.; Atkins, L.; Ryan, N.; Zarakowska, K.; Zschuentzsch, J.; Zuccolo, M.; Muellenborn, M.; Man, Y.-S.; Goodman, L.; Trad, M.; Chalandon, A. S.; Sansen, S.; Martinez-Fresno, M.; Badger, S.; Walther van Olden, R.; Rothmann, R.; Lehner, P.; Tschohl, C.; Baillon, L.; Gumus, G.; Gross, E.; Stefanov, R.; Iskrov, G.; Raycheva, R.; Kostadinov, K.; Mitova, E.; Einhorn, M.; Einhorn, Y.; Schepers, J.; Huebner, M.; Alves, F.; Iskandar, R.; Mayer, R.; Renieri, A.; Piperkova, A.; Gut, I.; Beltran, S.; Matthiesen, M. E.; Poetz, M.; Hansson, M.; Trollmann, R.; Agolini, E.; Ottombrino, S.; Novelli, A.; Bertini, E.; Selvatici, R.; Farne, M.; Fortunato, F.; Ferlini, A.: Genetic newborn screening and digital technologies: A project protocol based on a dual approach to shorten the rare diseases diagnostic path in Europe. PLOS ONE 18 (11), e0293503 (2023)

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17.

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Khan, A.; Markus, M. A.; Svetlove, A.; Hülsmann, S.; Alves, F.; Dullin, C.: Longitudinal x-ray based lung function measurement for monitoring Nintedanib treatment response in a mouse model of lung fibrosis. Scientific Reports 13 (1), 18637 (2023)

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18.

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Nolte, P.; Brettmacher, M.; Gröger, C. J.; Gellhaus, T.; Svetlove, A.; Schilling, A. F.; Alves, F.; Russmann, C.; Dullin, C.: Spatial correlation of 2D hard-tissue histology with 3D microCT scans through 3D printed phantoms. Scientific Reports 13 (1), 18479 (2023)

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19.

Journal Article

Pinkert-Leetsch, D.; Frohn, J.; Ströbel, P.; Alves, F.; Salditt, T.; Missbach-Guentner, J.: Three-dimensional analysis of human pancreatic cancer specimens by phase-contrast based X-ray tomography – the next dimension of diagnosis. Cancer Imaging 23, 43 (2023)

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20.

Journal Article

Pantelaiou-Prokaki, G.; Reinhardt, O.; Georges, N. S.; Agorku, D. J.; Hardt, O.; Prokakis, E.; Mieczkowska, I. K.; Deppert, W.; Wegwitz, F.; Alves, F.: Basal-like mammary carcinomas stimulate cancer stem cell properties through AXL-signaling to induce chemotherapy resistance. International Journal of Cancer 152 (9), pp. 1916 - 1932 (2023)

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21.

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Czaplinska, D.; Ialchina, R.; Andersen, H. B.; Yao, J.; Stigliani, A.; Dannesboe, J.; Flinck, M.; Chen, X.; Mitrega, J.; Gnosa, S. P. et al.; Dmytriyeva, O.; Alves, F.; Napp, J.; Sandelin, A.; Pedersen, S. F.: Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness. International Journal of Cancer 152 (6), pp. 1210 - 1225 (2023)

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22.

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Albers, J.; Wagner, W. L.; Fiedler, M. O.; Rothermel, A.; Wuennemann, F.; Di Lillo, F.; Dreossi, D.; Sodini, N.; Baratella, E.; Confalonieri, M. et al.; Arfelli, F.; Kalenka, A.; Lotz, J.; Biederer, J.; Wielpuetz, M. O.; Kauczor, H.-U.; Alves, F.; Tromba, G.; Dullin, C.: High resolution propagation-based lung imaging at clinically relevant X-ray dose levels. Scientific Reports 13 (1), 4788 (2023)

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23.

Journal Article

Khorenko, M.; Pfeifer, J.; Napp, J.; Meschkov, A.; Alves, F.; Schepers, U.; Feldmann, C.: Theranostic inorganic–organic hybrid nanoparticles with a cocktail of chemotherapeutic and cytostatic drugs. Journal of Materials Chemistry B 11, pp. 3635 - 3649 (2023)

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24.

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Markus, M. A.; Ferrari, D. P.; Alves, F.; Ramos Gomes, F.: Effect of tissue fixation on the optical properties of structural components assessed by non-linear microscopy imaging. Biomedical Optics Express 14 (8), pp. 3988 - 4002 (2023)

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25.

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Nolte, P.; Dullin, C.; Svetlove, A.; Brettmacher, M.; Russmann, C.; Schilling, A. F.; Alves, F.; Stock, B.: Current Approaches for Image Fusion of Histological Data with Computed Tomography and Magnetic Resonance Imaging. Radiology Research and Practice 2022, 6765895 (2022)

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26.

Journal Article

Ritschel, C.; Napp, J.; Alves, F.; Feldmann, C.: Monitoring nanoparticle dissolution via fluorescence-colour shift. Nanoscale 14 (43), pp. 16249 - 16255 (2022)

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27.

Journal Article

Pinkert-Leetsch, D.; Rost, J. U.; Schmiedeknecht, M. U. H.; Stadelmann, C.; Alves, F.; Missbach-Guentner, J.: The murine male reproductive organ at a glance: Three-dimensional insights and virtual histology using label-free light sheet microcopy. Andrology 10 (8), pp. 1660 - 1672 (2022)

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28.

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Werner, M.; Dyas, A.; Parfentev, I.; Schmidt, G. E.; Mieczkowska, I. K.; Müller-Kirschbaum, L. C.; Müller, C.; Kalkhof, S.; Reinhardt, O.; Urlaub, H. et al.; Alves, F.; Gallwas, J.; Prokakis, E.; Wegwitz, F.: ROBO3s: a novel ROBO3 short isoform promoting breast cancer aggressiveness. Cell Death and Disease 13, 762 (2022)

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29.

Journal Article

Dullin, C.; Svetlove, A.; Zschuntzsch, J.; Alves, F.: Simultaneous assessment of lung morphology and respiratory motion in retrospectively gated in-vivo microCT of free breathing anesthetized mice. Scientific Reports 12 (1), 13299 (2022)

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30.

Journal Article

Ramos-Gomes, F.; Ferreira, N.; Alves, F.; Markus, M. A.: An alternative technique for monitoring the live interaction of monocytes and tumor cells with nanoparticles in the mouse lung. Bio-protocol 12 (2), e4293 (2022)

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31.

Journal Article

Hermasch, M. A.; Janning, H.; Perera, R. P.; Schnabel, V.; Rostam, N.; Ramos Gomes, F.; Muschalek, W.; Bennemann, A.; Alves, F.; Ralser, D. J. et al.; Betz, R. C.; Schön, M. P.; Dosch, R.; Frank, J.: Evolutionary distinct roles of γ-secretase subunit nicastrin in zebrafish and humans. Journal of Dermatological Science 105 (2), pp. 80 - 87 (2022)

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32.

Journal Article

Pfeifer, R.; Henze, J.; Wittich, K.; Gosselink, A.; Kinkhabwala, A.; Gremse, F.; Bleilevens, C.; Bigott, K.; Jungblut, M.; Hardt, O. et al.; Alves, F.; Al Rawashdeh, W.: A multimodal imaging workflow for monitoring CAR T cell therapy against solid tumor from whole-body to single-cell level. Theranostics 12 (11), pp. 4834 - 4850 (2022)

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33.

Journal Article

Sabljo, K.; Napp, J.; Alves, F.; Feldmann, C.: pH-Dependent fluorescence of [La(OH)₂]⁺[ARS]^- hybrid nanoparticles for intracellular pH-sensing. Chemical Communications 58 (67), pp. 9417 - 9420 (2022)

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34.

Journal Article

Svetlove, A.; Albers, J.; Huelsmann, S.; Markus, M. A.; Zschuentzsch, J.; Alves, F.; Dullin, C.: Non-Invasive Optical Motion Tracking Allows Monitoring of Respiratory Dynamics in Dystrophin-Deficient Mice. Cells 11 (5), 918 (2022)

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35.

Journal Article

Khan, A.; Ramos Gomes, F.; Markus, M. A.; Mietsch, M.; Hinkel, R.; Alves, F.: Label-free imaging of age-related cardiac structural changes in non-human primates using multiphoton nonlinear microscopy. Biomedical Optics Express (2021)

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36.

Journal Article

Götze, T.; Soto-Bernardini, M. C.; Zhang, M.; Mießner, H.; Linhoff, L.; Brzózka, M. M.; Velanac, V.; Dullin, C.; Ramos Gomes, F.; Peng, M. et al.; Husseini, H.; Schifferdecker, E.; Fledrich, R.; Sereda, M. W.; Willig, K.; Alves, F.; Rossner, M. J.; Nave, K.-A.; Zhang, W.; Schwab, M. H.: Hyperactivity is a Core Endophenotype of Elevated Neuregulin-1 Signaling in Embryonic Glutamatergic Networks. SCHIZOPHRENIA BULLETIN 47 (5), pp. 1409 - 1420 (2021)

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37.

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Sier, V. Q.; de Vries, M. R.; van der Vorst, J. R.; Vahrmeijer, A. L.; van Kooten, C.; Cruz, L. J.; de Geus-Oei, L.-F.; Ferreira, V.; Sier, C. F. M.; Alves, F. et al.; Muthana, M.: Cell-based tracers as trojan horses for image-guided surgery. International Journal of Molecular Sciences 22 (2), 755 (2021)

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38.

Journal Article

Albers, J.; Svetlove, A.; Alves, J.; Kraupner, A.; di Lillo, F.; Markus, A.; Tromba, G.; Alves, F.; Dullin, C.: Elastic transformation of histological slices allows precise co-registration with microCT data sets for a refined virtual histology approach. Scientific Reports 11, 10846 (2021)

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39.

Journal Article

Dullin, C.; di Lillo, F.; Svetlove, A.; Albers, J.; Wagner, W.; Markus, A.; Sodini, N.; Dreossi, D.; Alves, F.; Tromba, G.: Multiscale biomedical imaging at the SYRMEP beamline of Elettra - Closing the gap between preclinical research and patient applications. Physics Open 6, 100050, p. 100050 (2021)

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40.

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Khan, A.; Markus, A.; Rittmann, T.; Albers, J.; Alves, F.; Hülsmann, S.; Dullin, C.: Simple low dose radiography allows precise lung volume assessment in mice. Scientific Reports 11, 4163 (2021)

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41.

Journal Article

Ramos Gomes, F.; Ferreira, N.; Kraupner, A.; Alves, F.; Markus, A.: Ex vivo Live Cell Imaging of Nanoparticle-Cell Interactions in the Mouse Lung. Frontiers in Bioengineering and Biotechnology 8 (2020)

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42.

Journal Article

Reichardt, M.; Frohn, J.; Khan, A.; Alves, F.; Salditt, T.: Multi-scale X-ray phase-contrast tomography of murine heart tissue. Biomedical Optics Express 11, p. 2633 (2020)

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43.

Journal Article

Reichardt, M.; Töpperwien, M.; Khan, A.; Alves, F.; Salditt, T.: Fiber orientation in a whole mouse heart reconstructed by laboratory phase-contrast micro-CT. Journal of Medical Imaging 7 (2) (2020)

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44.

Journal Article

Nicolas, J.-D.; Bernhardt, M.; Schlick, S. F.; Tiburcy, M.; Zimmermann, W.-H.; Khan, A.; Markus, A.; Alves, F.; Toischer, K.; Salditt, T.: X-ray diffraction imaging of cardiac cells and tissue. Progress in Biophysics and Molecular Biology 144, pp. 151 - 165 (2019)

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45.

Journal Article

Nifontova, G.; Ramos Gomes, F.; Baryshnikova, M.; Alves, F.; Nabiev, I.; Sukhanova, A.: Cancer cell targeting with functionalized quantum dot-encoded polyelectrolyte microcapsules. Frontiers in Chemistry 7, 34 (2019)

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46.

Journal Article

Ramos Gomes, F.; Möbius, W.; Bonacina, L.; Alves, F.; Markus, M. A.: Bismuth ferrite second harmonic nanoparticles for pulmonary macrophage tracking. Small 15 (4), 1803776 (2019)

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47.

Journal Article

Töpperwien, M.; Markus, A.; Alves, F.; Salditt, T.: Contrast enhancement for visualizing neuronal cytoarchitecture by propagation-based x-ray phase-contrast tomography. NeuroImage 199, pp. 70 - 80 (2019)

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48.

Journal Article

Napp, J.; Markus, M. A.; Heck, J. G.; Dullin, C.; Möbius, W.; Gorpas, D.; Feldmann, C.; Alves, F.: Therapeutic fluorescent hybrid nanoparticles for traceable delivery of glucocorticoids to inflammatory sites. Theranostics 8 (22), pp. 6367 - 6383 (2018)

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49.

Journal Article

Wagner, W. L.; Wuennemann, F.; Pacilé, S.; Albers, J.; Arfelli, F.; Dreossi, D.; Biederer, J.; Konietzke, P.; Stiller, W.; Wielpütz, M. O. et al.; Accardo, A.; Confalonieri, M.; Cova, M.; Lotz, J.; Alves, F.; Kauczor, H.-U.; Tromba, G.; Dullin, C.: Towards synchrotron phase-contrast lung imaging in patients – a proof-of-concept study on porcine lungs in a human-scale chest phantom. Journal of Synchrotron Radiation 25 (6), pp. 1827 - 1832 (2018)

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50.

Journal Article

Saccomano, M.; Albers, J.; Tromba, G.; Dobrivojevic Radmilovic, M.; Gajovic, S.; Alves, F.; Dullin, C.: Synchrotron inline phase contrast μCT enables detailed virtual histology of embedded soft-tissue samples with and without staining. Journal of Synchrotron Radiation 25, pp. 1153 - 1161 (2018)

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