Publications of Lena Spieth
All genres
Journal Article (11)
2024
Journal Article
223 (1), e201902050 (2024)
Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity. Journal of Cell Biology 2023
Journal Article
618, pp. 349 - 357 (2023)
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease. Nature 2022
Journal Article
8 (37), eabo7639 (2022)
Ketogenic diet uncovers differential metabolic plasticity of brain cells. Science Advances
Journal Article
45 (4), pp. 272 - 283 (2022)
Local cholesterol metabolism orchestrates remyelination. Trends in Neurosciences 2021
Journal Article
27, pp. 4974 - 4983 (2021)
NMDAR1 autoantibodies amplify behavioral phenotypes of genetic white matter inflammation: a mild encephalitis model with neuropsychiatric relevance. Molecular Psychiatry
Journal Article
37 (4), 109889 (2021)
Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice. Cell Reports
Journal Article
3 (1), vdab140 (2021)
Anesthesia triggers drug delivery to experimental glioma in mice by hijacking caveolar transport. Neuro-Oncology Advances
Journal Article
24, pp. 47 - 60 (2021)
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis. Nature Neuroscience 2020
Journal Article
68 (3), pp. 600 - 616 (2020)
Liver kinase B1 depletion from astrocytes worsens disease in a mouse model of multiple sclerosis. Glia 2019
Journal Article
138, pp. 147 - 161 (2019)
Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus-Merzbacher disease. Acta Neuropathologica 2017
Journal Article
5, 94 (2017)
Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model. Acta Neuropathologica Communications Preprint (2)
2023
Preprint
Oligodendrocytes and neurons contribute to amyloid-β deposition in Alzheimer’s disease. (2023)
2021
Preprint
Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer's disease. (2021)