Publications of Luisa M. Welp

Gobran, M.; Politi, A. Z.; Welp, L. M.; Jakobi, J.; Urlaub, H.; Lenart, P.: PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division. The EMBO Journal 44 (7), pp. 1891 - 1920 (2025)

Fendler, N. L.; Ly, J.; Welp, L. M.; Lu, D.; Schulte, F.; Urlaub, H.; Vos, S. M.: Identification and characterization of a human MORC2 DNA binding region that is required for gene silencing. Nucleic Acids Research 53 (4), gkae1273 (2025)

Lavdovskaia, E.; Hanitsch, E.; Linden, A.; Pašen, M.; Challa, V.; Horokhovskyi, Y.; Roetschke, H. P.; Nadler, F.; Welp, L.; Steube, E. et al.; Heinrichs, M.; Mai, M. M.-Q.; Urlaub, H.; Liepe, J.; Richter-Dennerlein, R.: A roadmap for ribosome assembly in human mitochondria. Nature Structural & Molecular Biology 31, pp. 1898 - 1908 (2024)

Harasimov, K.; Gorry, R. L.; Welp, L. M.; Penir, S. M.; Horokhovskyi, Y.; Cheng, S.; Takaoka, K.; Stützer, A.; Frombach, A.-S.; Taylor Tavares, A. L. et al.; Raabe, M.; Haag, S.; Saha, D.; Grewe, K.; Schipper, V.; Rizzoli, S. O.; Urlaub, H.; Liepe, J.; Schuh, M.: The maintenance of oocytes in the mammalian ovary involves extreme protein longevity. Nature Cell Biology 26, pp. 1124 - 1138 (2024)

Siraj, A.; Bouwmeester, R.; Declercq, A.; Welp, L.; Chernev, A.; Wulf, A.; Urlaub, H.; Martens, L.; Degroeve, S.; Kohlbacher, O. et al.; Sachsenberg, T.: Intensity and retention time prediction improves the rescoring of protein‐nucleic acid cross‐links. Proteomics 24 (8), 2300144 (2024)

Kanwal, N.; Krogh, N.; Memet, I.; Lemus-Diaz, N.; Thomé, C. C.; Welp, L. M.; Mizi, A.; Hackert, P.; Papantonis, A.; Urlaub, H. et al.; Nielsen, H.; Bohnsack, K. E.; Bohnsack, M. T.: GPATCH4 regulates rRNA and snRNA 2′-O-methylation in both DHX15-dependent and DHX15-independent manners. Nucleic Acids Research 52 (4), pp. 1953 - 1974 (2024)

Jentoft, I. M. A.; Bäuerlein, F. J.B.; Welp, L. M.; Cooper, B. H.; Petrovic, A.; So, C.; Penir, S. M.; Politi, A. Z.; Horokhovskyi, Y.; Takala, I. et al.; Eckel, H.; Moltrecht, R.; Lenart, P.; Cavazza, T.; Liepe, J.; Brose, N.; Urlaub, H.; Fernández-Busnadiego, R.; Schuh, M.: Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices. Cell 186 (24), pp. 5308 - 5327.e25 (2023)

Grahn, E.; Kaufmann, S. V.; Askarova, M.; Ninov, M.; Welp, L. M.; Berger, T.K.; Urlaub, H.; Kaupp, U.B.: Control of intracellular pH and bicarbonate by CO₂ diffusion into human sperm. Nature Communications 14, 5395 (2023)

Wolfram-Schauerte, M.; Pozhydaieva, N.; Grawenhoff, J.; Welp, L. M.; Silbern, I.; Wulf, A.; Billau, F. A.; Glatter, T.; Urlaub, H.; Jäschke, A. et al.; Höfer, K.: A viral ADP-ribosyltransferase attaches RNA chains to host proteins. Nature 620, pp. 1054 - 1062 (2023)

Witzenberger, M.; Burczyk, S.; Settele, D.; Mayer, W.; Welp, L. M.; Heiss, M.; Wagner, M.; Monecke, T.; Janowski, R.; Carell, T. et al.; Urlaub, H.; Hauck, S. M.; Voigt, A.; Niessing, D.: Human TRMT2A methylates tRNA and contributes to translation fidelity. Nucleic Acids Research 51 (16), pp. 8691 - 8710 (2023)

Quentin, D.; Schuhmacher, J.S.; Klink, B.U.; Lauer, J.; Shaikh, T.R.; Huis in ’t Veld, P.J.; Welp, L. M.; Urlaub, H.; Zerial, M.; Raunser, S.: Structural basis of mRNA binding by the human FERRY Rab5 effector complex. Molecular Cell 83 (11), pp. 1856 - 1871.e9 (2023)

Cheng, S.; Altmeppen, G.; So, C.; Welp, L.; Penir, S. M.; Ruhwedel, T.; Menelaou, K.; Harasimov, K.; Stützer, A.; Blayney, M. et al.; Elder, K.; Möbius, W.; Urlaub, H.; Schuh, M.: Mammalian Oocytes Store mRNAs in a Mitochondria-Associated Membraneless Compartment. Obstetrical & Gynecological Survey 78 (5), pp. 280 - 281 (2023)

Cheng, S.; Altmeppen, G.; So, C.; Welp, L.; Penir, S. M.; Ruhwedel, T.; Menelaou, K.; Harasimov, K.; Stützer, A.; Blayney, M. et al.; Elder, K.; Möbius, W.; Urlaub, H.; Schuh, M.: Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment. Science 378 (6617), eabq4835 (2022)

Koutsoumparis, A.; Welp, L.; Wulf, A.; Urlaub, H.; Meierhofer, D.; Börno, S.; Timmermann, B.; Busack, I.; Bringmann, H.: Sleep neuron depolarization promotes protective gene expression changes and FOXO activation. Current Biology 32 (10), pp. 2248 - 2262.e9 (2022)

Blersch, K. F.; Burchert, J.-P.; August, S.-C.; Welp, L.; Neumann, P.; Köster, S.; Urlaub, H.; Ficner, R.: Structural model of the M7G46 methyltransferase TrmB in complex with tRNA. RNA Biology 18 (12), pp. 2466 - 2479 (2021)

Sievers, K.; Welp, L.; Urlaub, H.; Ficner, R.: Structural and functional insights into human tRNA guanine transgylcosylase. RNA Biology 18 (Suppl. 1), pp. 382 - 396 (2021)

Stützer, A.; Welp, L.; Raabe, M.; Sachsenberg, T.; Kappert, C.; Wulf, A.; Lau, A. M.; David, S.-S.; Chernev, A.; Kramer, K. et al.; Politis, A.; Kohlbacher, O.; Fischle, W.; Urlaub, H.: Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry. Nature Communications 11, 5250 (2020)

Welp, L. M.; Sachsenberg, T.; Wulf, A.; Chernev, A.; Horokhovskyi, Y.; Neumann, P.; Pašen, M.; Siraj, A.; Raabe, M.; Johannsson, S. et al.; Schmitzova, J.; Netz, E.; Pfeuffer, J.; He, Y.; Fritzemeier, K.; Delanghe, B.; Viner, R.; Vos, S. M.; Cramer, P.; Ficner, R.; Liepe, J.; Kohlbacher, O.; Urlaub, H.: Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid–protein interaction sites by mass spectrometry. bioRxiv (2024)