Publications of Melina Schuh

Bellou, E.; Zielinska, A.; Mönnich, E. U.; Schweizer, N.; Politi, A. Z.; Wellecke, A.; Sibold, C.; Tandler-Schneider, A.; Schuh, M.: Chromosome architecture and low cohesion bias acrocentric chromosomes towards aneuploidy during mammalian meiosis. Nature Communications 15, 10713 (2024)

Cheng, S.; Schuh, M.: Two mechanisms repress cyclin B1 translation to maintain prophase arrest in mouse oocytes. Nature Communications 15, 10044 (2024)

Sharma, N.; Coticchio, G.; Borini, A.; Tachibana, K.; Nasmyth, K. A.; Schuh, M.: Changes in DNA repair compartments and cohesin loss promote DNA damage accumulation in aged oocytes. Current Biology 34 (22), pp. 5131 - 5148.e6 (2024)

Thomas, C.; Marx, T. L.; Penir, S. M.; Schuh, M.: Ex vivo imaging reveals the spatiotemporal control of ovulation. Nature Cell Biology 26, pp. 1997 - 2008 (2024)

Harasimov, K.; Gorry, R. L.; Welp, L. M.; Penir, S. M.; Horokhovskyi, Y.; Cheng, S.; Takaoka, K.; Stützer, A.; Frombach, A.-S.; Taylor Tavares, A. L. et al.; Raabe, M.; Haag, S.; Saha, D.; Grewe, K.; Schipper, V.; Rizzoli, S. O.; Urlaub, H.; Liepe, J.; Schuh, M.: The maintenance of oocytes in the mammalian ovary involves extreme protein longevity. Nature Cell Biology 26, pp. 1124 - 1138 (2024)

Nikalayevich, E.; Letort, G.; de Labbey, G.; Todisco, E.; Shihabi, A.; Turlier, H.; Voituriez, R.; Yahiatene, M.; Pollet-Villard, X.; Innocenti, M. et al.; Schuh, M.; Terret, M.-E.; Verlhac, M.-H.: Aberrant cortex contractions impact mammalian oocyte quality. Developmental Cell 59 (7), pp. 841 - 852.e7 (2024)

Zaffagnini, G.; Cheng, S.; Salzer, M.C.; Pernaute, B.; Duran, J.M.; Irimia, M.; Schuh, M.; Böke, E.: Mouse oocytes sequester aggregated proteins in degradative super-organelles. Cell 187 (5), pp. 1109 - 1126.e21 (2024)

Jentoft, I. M. A.; Bäuerlein, F. J.B.; Welp, L. M.; Cooper, B. H.; Petrovic, A.; So, C.; Penir, S. M.; Politi, A. Z.; Horokhovskyi, Y.; Takala, I. et al.; Eckel, H.; Moltrecht, R.; Lenart, P.; Cavazza, T.; Liepe, J.; Brose, N.; Urlaub, H.; Fernández-Busnadiego, R.; Schuh, M.: Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices. Cell 186 (24), pp. 5308 - 5327.e25 (2023)

Cheng, S.; Altmeppen, G.; So, C.; Welp, L.; Penir, S. M.; Ruhwedel, T.; Menelaou, K.; Harasimov, K.; Stützer, A.; Blayney, M. et al.; Elder, K.; Möbius, W.; Urlaub, H.; Schuh, M.: Mammalian Oocytes Store mRNAs in a Mitochondria-Associated Membraneless Compartment. Obstetrical & Gynecological Survey 78 (5), pp. 280 - 281 (2023)

Harasimov, K.; Uraji, J.; Mönnich, E. U.; Holubcová, Z.; Elder, K.; Blayney, M.; Schuh, M.: Actin-driven chromosome clustering facilitates fast and complete chromosome capture in mammalian oocytes. Nature Cell Biology (2023)

Cheng, S.; Altmeppen, G.; So, C.; Welp, L.; Penir, S. M.; Ruhwedel, T.; Menelaou, K.; Harasimov, K.; Stützer, A.; Blayney, M. et al.; Elder, K.; Möbius, W.; Urlaub, H.; Schuh, M.: Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment. Science 378 (6617), eabq4835 (2022)

Cavazza, T.; Schuh, M.: Stressful start causes chromosome errors in human embryos. Nature 609, pp. 683 - 684 (2022)

Charalambous, C.; Webster, A.; Schuh, M.: Aneuploidy in mammalian oocytes and the impact of maternal ageing. Nature Reviews Molecular Cell Biology (2022)

So, C.; Menelaou, K.; Uraji, J.; Harasimov, K.; Steyer, A. M.; Seres, K. B.; Bucevičius, J.; Lukinavicius, G.; Möbius, W.; Sibold, C. et al.; Tandler-Schneider, A.; Eckel, H.; Moltrecht, R.; Blayney, M.; Elder, K.; Schuh, M.: Mechanism of spindle pole organization and instability in human oocytes. Science 375 (6581), eabj3944 (2022)

Cavazza, T.; Takeda, Y.; Politi, A. Z.; Aushev, M.; Aldag, P.; Baker, C.; Choudhary, M.; Bucevičius, J.; Lukinavičius, G.; Elder, K. et al.; Blayney, M.; Lucas-Hahn, A.; Niemann, H.; Herbert, M.; Schuh, M.: Parental genome unification is highly error-prone in mammalian embryos. Cell 184 (11), pp. 2860 - 2877.e22 (2021)

So, C.; Cheng, S.; Schuh, M.: Phase separation during germline development. Trends in Cell Biology 31 (4), pp. 254 - 268 (2021)

Wartosch, L.; Schindler, K.; Schuh, M.; Gruhn, J. R.; Hoffmann, E.R.; McCoy, R. C.; Xing, J.: Origins and mechanisms leading to aneuploidy in human eggs. Prenatal Diagnosis 41 (5), pp. 620 - 630 (2021)

Scheffler, K.; Uraji, J.; Jentoft, I.; Cavazza, T.; Mönnich, E.; Mogessie, B.; Schuh, M.: Two mechanisms drive pronuclear migration in mouse zygotes. Nature Communications 12, 841 (2021)

Thomas, C.; Cavazza, T.; Schuh, M.: Aneuploidy in human eggs: contributions of the meiotic spindle. Biochemical Society Transactions 49 (1), pp. 107 - 118 (2021)

ElInati, E.; Zielinska, A.; McCarthy, A.; Kubikova, N.; Maciulyte, V.; Mahadevaiah, S.; Sangrithi, M. N.; Ojarikre, O.; Wells, D.; Niakan, K. K. et al.; Schuh, M.; Turner, J. M. A.: The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes. Nature Communications 11, 2598 (2020)