Publications

Journal Article (590)

Journal Article
Ebert, K.E.; Belov, V. N.; John, M.; Weiss, T.; Brüning, T.; Hayen, H.; Koch, H.M.; Bury, D.: Identification, Organic Synthesis, and Sensitive Analysis of a cis-Homosalate-Specific Exposure Biomarker. Chemical Research in Toxicology 37 (2), pp. 285 - 291 (2024)
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Knorr, G.; Bossi, M.L.; Butkevich, A.N.; Hell, S. W.: Synthesis of Thioxanthone 10,10-Dioxides and Sulfone-Fluoresceins via Pd-Catalyzed Sulfonylative Homocoupling. Organic Letters 26 (4), pp. 945 - 949 (2024)
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Wegener, J. W.; Mitronova, G.; Elshareif, L.; Quentin, C.; Belov, V. N.; Pochechueva, T.; Hasenfuss, G.; Ackermann, L.; Lehnart, S. E.: A dual-targeted drug inhibits cardiac ryanodine receptor Ca2+ leak but activates SERCA2a Ca2+ uptake. Life science alliance 7 (2), e202302278 (2024)
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Hintze, A.; Lange, F.; Steyer, A. M.; Anstatt, J.; Möbius, W.; Jakobs, S.; Wichmann, C.: Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus. iScience 27 (1), 108700 (2024)
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Palikyras, S.; Sofiadis, K.; Stavropoulou, A.; Danieli-Mackay, A.; Varamogianni-Mamatsi, V.; Hörl, D.; Nasiscionyte, S.; Zhu, Y.; Papadionysiou, I.; Papadakis, A. et al.; Josipovic, N.; Zirkel, A.; O'Connell, A.; Loughran, G.; Keane, J.; Michel, A.; Wagner, W.; Beyer, A.; Harz, H.; Leonhardt, H.; Lukinavičius, G.; Nikolaou, C.; Papantonis, A.: Rapid and synchronous chemical induction of replicative-like senescence via a small molecule inhibitor. Aging Cell, e14083 (2024)
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DʼEste, E.; Lukinavičius, G.; Lincoln, R.; Opazo, F.; Fornasiero, E.F.: Advancing cell biology with nanoscale fluorescence imaging: essential practical considerations. Trends in Cell Biology (2024)
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Kolarski, D.; Steinbach, P.; Bannwarth, C.; Klaue, K.; Hecht, S.: Diaryltriazolium Photoswitch: Reaching a Millisecond Cycloreversion with High Stability and NIR Absorption. Angewandte Chemie International Edition, e202318015 (2023)
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Mitronova, G.; Quentin, C.; Belov, V. N.; Wegener, J.W.; Kiszka, K. A.; Lehnart, S.E.: 1,4-Benzothiazepines with Cyclopropanol Groups and Their Structural Analogues Exhibit Both RyR2-Stabilizing and SERCA2a-Stimulating Activities. Journal of Medicinal Chemistry 66 (23), pp. 15761 - 15775 (2023)
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Breindl, M.; Spitzer, D.; Gerasimaitė, R.; Kairys, V.; Schubert, T.; Henfling, R.; Schwartz, U.; Lukinavičius, G.; Manelytė, L.: Biochemical and cellular insights into the Baz2B protein, a non-catalytic subunit of the chromatin remodeling complex. Nucleic Acids Research, gkad1096 (2023)
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Aktalay, A.; Khan, T. A.; Bossi, M. L.; Belov, V. N.; Hell, S. W.: Photoactivatable carbo- and silicon-rhodamines and their application in MINFLUX nanoscopy. Angewandte Chemie 135 (41), e202302781 (2023)
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Orange kedem, R.; Opatovski, N.; Xiao, D.; Ferdman, B.; Alalouf, O.; Pal, S. K.; Wang, Z.; von der Emde, H.; Weber, M.; Sahl, S. J. et al.; Ponjavic, A.; Arie, A.; Hell, S. W.; Shechtman, Y.: Near index matching enables solid diffractive optical element fabrication via additive manufacturing. Light: Science & Applications 12, 222 (2023)
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Kim, D.; Stoldt, S.; Weber, M.; Jakobs, S.; Belov, V. N.; Hell, S. W.: A Bright Surprise: Live-Cell Labeling with Negatively Charged Fluorescent Probes based on Disulfonated Rhodamines and HaloTag. Chemistry Methods 3 (9), e202200076 (2023)
Journal Article
Aktalay, A.; Lincoln, R.; Heynck, L.; Lima, M. A. d. R. B. F.; Butkevich, A. N.; Bossi, M. L.; Hell, S. W.: Bioorthogonal Caging-Group-Free Photoactivatable Probes for Minimal-Linkage-Error Nanoscopy. ACS Central Science 9 (8), pp. 1581 - 1590 (2023)
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Zelená, A.; Blumberg, J.; Probst, D.; Gerasimaitė, R.; Lukinavičius, G.; Schwarz, U. S.; Köster, S.: Force generation in human blood platelets by filamentous actomyosin structures. Biophysical Journal 122 (16), pp. 3340 - 3353 (2023)
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Michanski, S.; Henneck, T.; Mukhopadhyay, M.; Steyer, A. M.; Gonzalez, P.A.; Grewe, K.; Ilgen, P.; Gültas, M.; Fornasiero, E.F.; Jakobs, S. et al.; Möbius, W.; Vogl, C.; Pangršič, T.; Rizzoli, S.O.; Wichmann, C.: Age-dependent structural reorganization of utricular ribbon synapses. Frontiers in Cell and Developmental Biology 11, 1178992 (2023)
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Ebrahimi, V.; Stephan, T.; Kim, J.; Carravilla, P.; Eggeling, C.; Jakobs, S.; Han, K. Y.: Deep learning enables fast, gentle STED microscopy. Communications Biology 6 (1), 674 (2023)
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Pradhan, S.; Apaydin, S.; Bucevičius, J.; Gerasimaitė, R.; Kostiuk, G.; Lukinavičius, G.: Sequence-specific DNA labelling for fluorescence microscopy. Biosensors and Bioelectronics 230, 115256 (2023)
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Wrobel, S. A.; Koslitz, S.; Belov, V. N.; Bury, D.; Hayen, H.; Brüning, T.; Koch, H. M.; Käfferlein, H. U.: Quantitation of 6-chloronicotinic acid and 2-chloro-1,3-thiazole-5-carboxylic acid and their glycine conjugates in human urine to assess neonicotinoid exposure. Environmental Research 226, 115609 (2023)
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Remmel, M.; Scheiderer, L.; Butkevich, A.; Bossi, M. L.; Hell, S. W.: Accelerated MINFLUX Nanoscopy, through Spontaneously Fast-Blinking Fluorophores. Small 19 (12), 2206026 (2023)
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Wolff, J. O.; Scheiderer, L.; Engelhardt, T.; Engelhardt, J.; Matthias, J.; Hell, S. W.: MINFLUX dissects the unimpeded walking of kinesin-1. Science 379 (6636), pp. 1004 - 1010 (2023)
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Wrobel, S. A.; Bury, D.; Belov, V. N.; Klenk, J. M.; Hauer, B.; Hayen, H.; Martino-Andrade, A. J.; Koch, H. M.; Brüning, T.; Käfferlein, H. U.: Rapid quantification of seven major neonicotinoids and neonicotinoid-like compounds and their key metabolites in human urine. Analytica Chimica Acta 1239, 340680 (2023)
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Likhotkin, I.; Lincoln, R.; Bossi, M. L.; Butkevich, A.; Hell, S. W.: Photoactivatable Large Stokes Shift Fluorophores for Multicolor Nanoscopy. Journal of the American Chemical Society 145 (3), pp. 1530 - 1534 (2023)
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Bucevičius, J.; Gerasimaitė, R.; Kiszka, K. A.; Pradhan, S.; Kostiuk, G.; Koenen, T.; Lukinavičius, G.: A general highly efficient synthesis of biocompatible rhodamine dyes and probes for live-cell multicolor nanoscopy. Nature Communications 14 (1), 1306 (2023)
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Gürth, C.-M.; do Rego Barros Fernandes Lima, M.A.; Macarrón Palacios, V.; Cereceda Delgado, A. R.; Hubrich, J.; D'Este, E.: Neurofilament Levels in Dendritic Spines Associate with Synaptic Status. Cells 12 (6), 909 (2023)
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Gwosch, K. C.; Balzarotti, F.; Pape, J. K.; Hoess, P.; Ellenberg, J.; Ries, J.; Matti, U.; Schmidt, R.; Sahl, S. J.; Hell, S. W.: Reply to: Assessment of 3D MINFLUX data for quantitative structural biology in cells. Nature Methods 20, pp. 52 - 54 (2023)
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Savicheva, E. A.; Bossi, D. M. L.; Belov, V. N.; Hell, S. W.: Introduction of the Functional Amino Group at the meso Position of Cy3 and Cy5 Dyes: Synthesis, Stability, Spectra and Photolysis of 4-Amino-1-diazo-2-butanone Derivatives. ChemPhotoChem 7 (1), e202200222 (2023)
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Liu, T.; Stephan, T.; Chen, P.; Keller-Findeisen, J.; Chen, J.; Riedel, D.; Yang, Z.; Jakobs, S.; Chen, Z.: Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain. Proceedings of the National Academy of Sciences of the United States of America 119 (52), e2215799119 (2022)
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Gregor, C.: Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2. Scientific Reports 12 (1), 19039 (2022)
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Weber, M.; von der Emde, H.; Leutenegger, M.; Gunkel, P.; Sambandan, S.; Khan, T. A.; Keller-Findeisen, J.; Cordes, V. C.; Hell, S. W.: MINSTED nanoscopy enters the Ångström localization range. Nature Biotechnology (2022)
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Leutenegger, M.; Hell, S. W.: Calibration of Deformable Mirrors for Open-Loop Control. Sensors 22 (21), 8465 (2022)
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Engelhardt, J.; Ellerhoff, B.; Gürth, C.-M.; Sahl, S. J.; Hell, S. W.: Designing chromatic optical retarder stacks for segmented next-generation easySTED phase plates. Journal of Microscopy 288 (2), pp. 142 - 150 (2022)
Journal Article
Uno, K.; Kim, D.; Bucevicius, J.; Bossi, M. L.; Belov, V. N.; Hell, S. W.: Synthesis, structure–property relationships and absorbance modulation of highly asymmetric photochromes with variable oxidation and substitution patterns. Organic Chemistry Frontiers 9 (22), pp. 6295 - 6304 (2022)
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Stejerean-Todoran, I.; Zimmermann, K.; Gibhardt, C. S.; Vultur, A.; Ickes, C.; Shannan, B.; Rio, Z. B. d.; Wölling, A.; Cappello, S.; Sung, H.-M. et al.; Shumanska, M.; Zhang, X.; Nanadikar, M.; Latif, M. U.; Wittek, A.; Lange, F.; Waters, A.; Brafford, P.; Wilting, J.; Urlaub, H.; Katschinski, D. M.; Rehling, P.; Lenz, C.; Jakobs, S.; Ellenrieder, V.; Roesch, A.; Schön, M. P.; Herlyn, M.; Stanisz, H.; Bogeski, I.: MCU controls melanoma progression through a redox-controlled phenotype switch. EMBO Reports 23, e54746 (2022)
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Aktalay, A.; Ponsot, F.; Bossi, M. L.; Belov, V. N.; Hell, S. W.: Cleavable Linker Incorporation into a Synthetic Dye-Nanobody-Fluorescent Protein Assembly: FRET, FLIM and STED Microscopy. ChemBioChem: A European Journal of Chemical Biology 23 (18), e202200395 (2022)
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Willig, K. I.: In vivo super-resolution of the brain - How to visualize the hidden nanoplasticity? iScience 25 (9), 104961 (2022)
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Lincoln, R.; Bossi, M. L.; Remmel, M.; D'Este, E.; Butkevich, A. N.; Hell, S. W.: A general design of caging-group-free photoactivatable fluorophores for live-cell nanoscopy. Nature Chemistry 14 (9), pp. 1013 - 1020 (2022)
Journal Article
Ostersehlt, L.-M.; Jans, D. C.; Wittek, A.; Keller-Findeisen, J.; Inamdar, K.; Sahl, S.; Hell, S. W.; Jakobs, S.: DNA-PAINT MINFLUX nanoscopy. Nature Methods 19, pp. 1072 - 1075 (2022)
Journal Article
Mihaila, T. S.; Bäte, C.; Ostersehlt, L. M.; Pape, J. K.; Keller-Findeisen, J.; Sahl, S. J.; Hell, S. W.: Enhanced incorporation of subnanometer tags into cellular proteins for fluorescence nanoscopy via optimized genetic code expansion. Proceedings of the National Academy of Sciences of the USA 119 (29), e2201861119 (2022)
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Upmanyu, N.; Jin, J.; von der Emde, H.; Ganzella, M.; Bösche, L.; Malviya, V. N.; Zhuleku, E.; Politi, A. Z.; Ninov, M.; Silbern, I. et al.; Leutenegger, M.; Urlaub, H.; Riedel, D.; Preobraschenski, J.; Milosevic, I.; Hell, S. W.; Jahn, R.; Sambandan, S.: Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3. Neuron 110 (9), pp. 1483 - 1497 (2022)
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Bates, M.; Keller-Findeisen, J.; Przybylski, A.; Hüper, A.; Stephan, T.; Ilgen, P.; Cereceda Delgado, A.R.; D’Este, E.; Egner, A.; Jakobs, S. et al.; Sahl, S. J.; Hell, S. W.: Optimal precision and accuracy in 4Pi-STORM using dynamic spline PSF models. Nature Methods 19 (5), pp. 603 - 612 (2022)
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Wegner, W.; Steffens, H.; Gregor, C.; Wolf, F.; Willig, K. I.: Environmental enrichment enhances patterning and remodeling of synaptic nanoarchitecture as revealed by STED nanoscopy. eLife 11, e73603 (2022)
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Shojaei, H.; Bossi, M. L.; Belov, V. N.; Hell, S. W.: Bis-rhodamines bridged with a diazoketone linker: synthesis, structure, and photolysis. The Journal of Organic Chemistry 87, pp. 56 - 65 (2022)
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Urakawa, N.; Uno, K.; Sato, Y.; Higashiyama, T.; Sasaki, N.: Rapid Selective Proliferation of Mitochondria during Zygote Maturation in the Uniparental Inheritance of Physarum polycephalum. Cytologia 87 (2), pp. 163 - 168 (2022)
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Brüser, C.; Keller-Findeisen, J.; Jakobs, S.: The TFAM-to-mtDNA ratio defines inner-cellular nucleoid populations with distinct activity levels. Cell Reports 37 (8), 110000 (2021)
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Gerasimaite, R.; Bucevicius, J.; Kiszka, K.; Schnorrenberg, S.; Kostiuk, G.; Koenen, T.; Lukinavičius, G.: Blinking fluorescent probes for tubulin nanoscopy in living and fixed cells. ACS Chemical Biology 16 (11), pp. 2130 - 2136 (2021)
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Butkevich, A. N.; Weber, M.; Cereceda Delgado, A.R.; Ostersehlt, L. M.; d'Este, E.; Hell, S. W.: Photoactivatable fluorescent dyes with hydrophilic caging groups and their use in multicolor nanoscopy. Journal of the American Chemical Society 143 (44), pp. 18388 - 18393 (2021)
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Lohner, P.; Zmyslia, M.; Thurn, J.; Pape, J. K.; Gerasimaite, R.; Keller-Findeisen, J.; Groeer, S.; Deuringer, B.; Süss, R.; Walther, A. et al.; Hell, S. W.; Lukinavičius, G.; Hugel, T.; Jessen-Trefzer, C.: Inside a shell – organometallic catalysis inside encapsulin nanoreactors. Angewandte Chemie International Edition 133 (44), pp. 24028 - 24034 (2021)
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Bollmann, F.; Dohrke, J.-N.; Wurm, C. A.; Jans, D. C.; Jakobs, S.: Mitochondrial protein abundance gradients require the distribution of separated mitochondria. Biology 10 (7), 572 (2021)
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Konen, T.; Stumpf, D.; Grotjohann, T.; Jansen, I.; Bossi, M.; Weber, M.; Jensen, N. A.; Hell, S. W.; Jakobs, S.: The positive switching fluorescent protein Padron2 enables live-cell reversible saturable optical linear fluorescence transitions (RESOLFT) nanoscopy without sequential illumination steps. ACS Nano 15 (6), pp. 9509 - 9521 (2021)
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Quentin, C.; Gerasimaite, R.; Freidzon, A.; Atabekyan, L. S.; Lukinavičius, G.; Belov, V. N.; Mitronova, G.: Direct visualization of amlodipine intervention into living cells by means of fluorescence microscopy. Molecules 26 (10), 2997 (2021)
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