Publications of Michael Lidschreiber

Kabinger, F.; Doze, V.; Schmitzová, J.; Lidschreiber, M.; Dienemann, C.; Cramer, P.: Structural basis of SARS-CoV-2 polymerase inhibition by nonnucleoside inhibitor HeE1-2Tyr. Proceedings of the National Academy of Sciences of the United States of America 122 (10), e2419854122 (2025)

Lysakovskaia, K.; Devadas, A.; Schwalb, B.; Lidschreiber, M.; Cramer, P.: Promoter-proximal RNA polymerase II termination regulates transcription during human cell type transition. Nature Structural & Molecular Biology (2025)

Rengachari, S.; Hainthaler, T.; Oberthür, C.; Lidschreiber, M.; Cramer, P.: Mechanism of polyadenylation-independent RNA polymerase II termination. Nature Structural & Molecular Biology 32, pp. 339 - 345 (2025)

Engeholm, M.; Roske, J. J.; Oberbeckmann, E.; Dienemann, C.; Lidschreiber, M.; Cramer, P.; Farnung, L.: Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT. Molecular Cell 84 (18), pp. 3423 - 3437.e8 (2024)

Velychko, T.; Mohammad, E.; Ferrer-Vicens, I.; Parfentev, I.; Werner, M.; Studniarek, C.; Schwalb, B.; Urlaub, H.; Murphy, S.; Cramer, P. et al.; Lidschreiber, M.: CDK7 kinase activity promotes RNA polymerase II promoter escape by facilitating initiation factor release. Molecular Cell 84 (12), pp. 2287 - 2303.e10 (2024)

Palau, A.; Segerberg, F.; Lidschreiber, M.; Lidschreiber, K.; Naughton, A.J.; Needhamsen, M.; Jung, L.A.; Jagodic, M.; Cramer, P.; Lehmann, S. et al.; Carlsten, M.; Lennartsson, A.: Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells. Leukemia 37, pp. 1830 - 1841 (2023)

Ramasamy, S.; Aljahani, A.; Karpinska, M. A.; Cao, N. T. B.; Velychko, T.; Cruz, J. N.; Lidschreiber, M.; Oudelaar, A. M.: The Mediator complex regulates enhancer-promoter interactions. Nature Structural and Molecular Biology 30, pp. 991 - 1000 (2023)

Abril-Garrido, J.; Dienemann, C.; Grabbe, F.; Velychko, T.; Lidschreiber, M.; Wang, H.; Cramer, P.: Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Molecular Cell 83 (11), pp. 1798 - 1809.e7 (2023)

Xiong, L.; Tolen, E. A.; Choi, J.; Velychko, S.; Caizzi, L.; Velychko, T.; Adachi, K.; MacCarthy, C. M.; Lidschreiber, M.; Cramer, P. et al.; Schöler, H. R.: Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells. eLife 11, e71533 (2022)

Sahu, B.; Hartonen, T.; Pihlajamaa, P.; Wei, B.; Dave, K.; Zhu, F.; Kaasinen, E.; Lidschreiber, K.; Lidschreiber, M.; Daub, C. O. et al.; Cramer, P.; Kivioja, T.; Taipale, J.: Sequence determinants of human gene regulatory elements. Nature Genetics 54 (3), pp. 283 - 294 (2022)

Shao, R.; Kumar, B.; Lidschreiber, K.; Lidschreiber, M.; Cramer, P.; Elsässer, S. J.: Distinct transcription kinetics of pluripotent cell states. Molecular Systems Biology 18 (1), e10407 (2022)

Osman, S.; Mohammad, E.; Lidschreiber, M.; Stuetzer, A.; Bazsó, F. L.; Maier, K. C.; Urlaub, H.; Cramer, P.: The Cdk8 kinase module regulates interaction of the mediator complex with RNA polymerase II. Journal of Biological Chemistry 296, 100734 (2021)

Caizzi, L.; Monteiro-Martins, S.; Schwalb, B.; Lysakovskaya, K.; Schmitzova, J.; Sawicka, A.; Chen, Y.; Lidschreiber, M.; Cramer, P.: Efficient RNA polymerase II pause release requires U2 snRNP function. Molecular Cell 81 (9), pp. 1920 - 1934.e9 (2021)

Hillen, H. S.; Markov, D. A.; Wojtas, I. D.; Hofmann, K. B.; Lidschreiber, M.; Cowan, A. T.; Jones, J. L.; Temiakov, D.; Cramer, P.; Anikin, M.: The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs. Proceedings of the National Academy of Sciences of the USA 118 (15), e2009329118 (2021)

Sawicka, A.; Villamil, G.; Lidschreiber, M.; Darzacq, X.; Dugast‐Darzacq, C.; Schwalb, B.; Cramer, P.: Transcription activation depends on the length of the RNA polymerase II C‐terminal domain. EMBO Journal 40 (9), e107015 (2021)

Lidschreiber, K.; Jung, L. A.; von der Emd, H.; von der Emde, H.; Dave, K.; Taipale, J.; Cramer, P.; Lidschreiber, M.: Transcriptionally active enhancers in human cancer cells. Molecular Systems Biology 17 (1), e9873 (2021)

Hendriks, G. J.; Jung, L. A.; Larsson, A. J. M.; Lidschreiber, M.; Forsman, O. A.; Lidschreiber, K.; Cramer, P.; Sandberg, R.: NASC-seq monitors RNA synthesis in single cells. Nature Communications 10 (1), 3138 (2019)

Lidschreiber, M.; Easter, A. D.; Battaglia, S.; Rodríguez-Molina, J. B.; Casañal, A.; Carminati, M.; Baejen, C.; Grzechnik, P.; Maier, K. C.; Cramer, P. et al.; Passmore, L. A.: The APT complex is involved in non-coding RNA transcription and is distinct from CPF. Nucleic Acids Research 46 (21), pp. 11528 - 11538 (2018)

Battaglia, S.; Lidschreiber, M.; Bäjen, C.; Torkler, P.; Vos, S. M.; Cramer, P.: RNA-dependent chromatin association of transcription elongation factors and Pol II CTD kinases. eLife 6, e25637 (2017)

Bäjen, C.; Andreani, J.; Torkler, P.; Battaglia, S.; Schwalb, B.; Lidschreiber, M.; Maier, K. C.; Boltendahl, A.; Rus, P.; Esslinger, S. et al.; Söding, J.; Cramer, P.: Genome-wide analysis of RNA polymerase II termination at protein-coding genes. Molecular Cell 66 (1), pp. 38 - 49 (2017)