Publications of Christian Dienemann

Kabinger, F.; Doze, V.; Schmitzová, J.; Lidschreiber, M.; Dienemann, C.; Cramer, P.: Structural basis of SARS-CoV-2 polymerase inhibition by nonnucleoside inhibitor HeE1-2Tyr. Proceedings of the National Academy of Sciences of the United States of America 122 (10), e2419854122 (2025)

Faul, N.; Chen, S.-Y.; Lamberz, C.; Bruckner, M.; Dienemann, C.; Burg, T. P.: Cryo-iCLEM: Cryo correlative light and electron microscopy with immersion objectives. Journal of Structural Biology 217 (1), 108179 (2025)

Engeholm, M.; Roske, J. J.; Oberbeckmann, E.; Dienemann, C.; Lidschreiber, M.; Cramer, P.; Farnung, L.: Resolution of transcription-induced hexasome-nucleosome complexes by Chd1 and FACT. Molecular Cell 84 (18), pp. 3423 - 3437.e8 (2024)

Ibáñez de Opakua, A.; Pantoja, C. F.; Cima-Omori, M.-S.; Dienemann, C.; Zweckstetter, M.: Impact of distinct FG nucleoporin repeats on Nup98 self-association. Nature Communications 15, 3797 (2024)

Zhan, Y.; Grabbe, F.; Oberbeckmann, E.; Dienemann, C.; Cramer, P.: Three-step mechanism of promoter escape by RNA polymerase II. Molecular Cell 84 (9), pp. 1699 - 1710.e6 (2024)

Frieg, B.; Han, M.; Giller, K.; Dienemann, C.; Riedel, D.; Becker, S.; Andreas, L. B.; Griesinger, C.; Schröder, G. F.: Cryo-EM structures of lipidic fibrils of amyloid-β (1-40). Nature Communications 15, 1297 (2024)

Düring, J.; Wolter, M.; Toplak, J. J.; Torres, C.; Dybkov, O.; Fokkens, T. J.; Bohnsack, K. E.; Urlaub, H.; Steinchen, W.; Dienemann, C. et al.; Lorenz, S.: Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1. Nature Structural & Molecular Biology 31, pp. 364 - 377 (2024)

Chen, Y.; Kokic, G.; Dienemann, C.; Dybkov, O.; Urlaub, H.; Cramer, P.: Structure of the transcribing RNA polymerase II–Elongin complex. Nature Structural & Molecular Biology 30, pp. 1925 - 1935 (2023)

Garg, G.; Dienemann, C.; Farnung, L.; Schwarz, J.; Linden, A.; Urlaub, H.; Cramer, P.: Structural insights into human co-transcriptional capping. Molecular Cell 83 (14), pp. 2464 - 2477.e5 (2023)

Abril-Garrido, J.; Dienemann, C.; Grabbe, F.; Velychko, T.; Lidschreiber, M.; Wang, H.; Cramer, P.: Structural basis of transcription reduction by a promoter-proximal +1 nucleosome. Molecular Cell 83 (11), pp. 1798 - 1809.e7 (2023)

Schmitzová, J.; Cretu, C.; Dienemann, C.; Urlaub, H.; Pena, V.: Structural basis of catalytic activation in human splicing. Nature 617, pp. 842 - 850 (2023)

Schilbach, S.; Wang, H.; Dienemann, C.; Cramer, P.: Yeast PIC-mediator structure with RNA polymerase II C-terminal domain. Proceedings of the National Academy of Sciences of the United States of America 120 (15), e2220542120 (2023)

Dybkov, O.; Preußner, M.; El Ayoubi, L.; Feng, V.-Y.; Harnisch, C.; Merz, K.; Leupold, P.; Yudichev, P.; Agafonov, D. E.; Will, C. L. et al.; Girard, C.; Dienemann, C.; Urlaub, H.; Kastner, B.; Heyd, F.; Lührmann, R.: Regulation of 3′ splice site selection after step 1 of splicing by spliceosomal C* proteins. Science Advances 9 (9), eadf178 (2023)

Dienemann, C.: Towards automating single-particle cryo-EM data acquisition. IUCRJ 10 (Part 1), pp. 4 - 5 (2023)

Rengachari, S.; Schilbach, S.; Kaliyappan, T.; Gouge, J.; Zumer, K.; Schwarz, J.; Urlaub, H.; Dienemann, C.; Vannini, A.; Cramer, P.: Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nature Structural and Molecular Biology 29, pp. 1159 - 1169 (2022)

Frieg, B.; Antonschmidt, L.; Dienemann, C.; Geraets, J. A.; Najbauer, E. E.; Matthes, D.; de Groot, B. L.; Andreas, L. B.; Becker, S.; Griesinger, C. et al.; Schröder, G. F.: The 3D structure of lipidic fibrils of α-synuclein. Nature Communications 13 (1), 6810 (2022)

de Opakua, A. I.; Geraets, J. A.; Frieg, B.; Dienemann, C.; Savastano, A.; Rankovic, M.; Cima-Omori, M.-S.; Schröder, G. F.; Zweckstetter, M.: Molecular interactions of FG nucleoporin repeats at high resolution. Nature Chemistry 14, pp. 1278 - 1285 (2022)

Frieg, B.; Geraets, J. A.; Strohaeker, T.; Dienemann, C.; Mavroeidi, P.; Jung, B. C.; Kim, W. S.; Lee, S.-J.; Xilouri, M.; Zweckstetter, M. et al.; Schroeder, G. F.: Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein. Communications Biology 5 (1), 1040 (2022)

Antonschmidt, L.; Matthes, D.; Dervişoğlu, R.; Frieg, B.; Dienemann, C.; Leonov, A.; Nimerovsky, E.; Sant, V.; Ryazanov, S.; Giese, A. et al.; Schröder, G.; Becker, S.; de Groot, B. L.; Griesinger, C.; Andreas, L. B.: The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils. Nature Communications 13, pp. 5385 - 5394 (2022)

Dombrowski, M.; Engeholm, M.; Dienemann, C.; Dodonova, S. O.; Cramer, P.: Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory. Nature Structural & Molecular Biology 29 (5), pp. 493 - 501 (2022)