Publications of Johannes Hirrlinger

Schoknecht, K.; Baeza-Lehnert, F.; Hirrlinger, J.; Dreier, J. P.; Eilers, J.: Spreading depolarizations exhaust neuronal ATP in a model of cerebral ischemia. Proceedings of the National Academy of Sciences of the United States of America 122 (19), e2415358122 (2025)

Sasmita, A. O.; Ong, E. C.; Nazarenko, T.; Mao, S.; Komarek, L.; Thalmann, M.; Hantakova, V.; Spieth, L.; Berghoff, S. A.; Barr, H. J. et al.; Hingerl, M.; Börensen, F.; Hirrlinger, J.; Simons, M.; Stevens, B.; Depp, C.; Nave, K.-A.: Parental origin of transgene modulates amyloid-β plaque burden in the 5xFAD mouse model of Alzheimer’s disease. Neuron 113 (6), pp. 838 - 846.e4 (2025)

Furukawa, K.; Ikoma, Y.; Niino, Y.; Hiraoka, Y.; Tanaka, K.; Miyawaki, A.; Hirrlinger, J.; Matsui, K.: Dynamics of Neuronal and Astrocytic Energy Molecules in Epilepsy. Journal of Neurochemistry 169 (3), e70044 (2025)

Hochmuth, L.; Hirrlinger, J.: Physiological and Pathological Role of mTOR Signaling in Astrocytes. Neurochemical Research 50, 53 (2025)

Wolff, C.; John, D.; Winkler, U.; Hochmuth, L.; Hirrlinger, J.; Köhler, S.: Insulin and leptin acutely modulate the energy metabolism of primary hypothalamic and cortical astrocytes. Journal of Neurochemistry 169 (1), e16211 (2025)

Späte, E.; Zhou, B.; Sun, T.; Kusch, K.; Asadollahi, E.; Siems, S. B.; Depp, C.; Werner, H. B.; Saher, G.; Hirrlinger, J. et al.; Möbius, W.; Nave, K.-A.; Göbbels, S.: Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons. Glia 72 (8), pp. 1374 - 1391 (2024)

Bai, X.; Zhao, N.; Koupourtidou, C.; Fang, L.-P.; Schwarz, V.; Caudal, L. C.; Zhao, R.; Hirrlinger, J.; Walz, W.; Bian, S. et al.; Huang, W.; Ninkovic, J.; Kirchhoff, F.; Scheller, A.: In the mouse cortex, oligodendrocytes regain a plastic capacity, transforming into astrocytes after acute injury. Developmental Cell 58 (13), pp. 1153 - 1169.e5 (2023)

Sadigurschi, N.; Scrift, G.; Hirrlinger, J.; Golan, H. M. M.: Genetic impairment of folate metabolism regulates cortical interneurons and social behavior. Frontiers in Neuroscience 17, 1203262 (2023)

Bohmbach, K.; Henneberger, C.; Hirrlinger, J.: Astrocytes in memory formation and maintenance. Essays in Biochemistry 67 (1), pp. 107 - 117 (2023)

Schoknecht, K.; Hirrlinger, J.; Eilers, J.: Transient astrocytic accumulation of fluorescein during spreading depolarizations. Neurobiology of Disease 178, 106026 (2023)

Köhler, S.; Winkler, U.; Junge, T.; Lippmann, K.; Eilers, J.; Hirrlinger, J.: Gray and white matter astrocytes differ in basal metabolism but respond similarly to neuronal activity. Glia 71 (2), pp. 229 - 244 (2023)

Oke, Y.; Miwakeichi, F.; Oku, Y.; Hirrlinger, J.; Hülsmann, S.: Cell types and synchronous-activity patterns of inspiratory neurons in the preBötzinger complex of mouse medullary slices during early postnatal development. Scientific Reports 13, 586 (2023)

Düking, T.; Spieth, L.; Berghoff, S. A.; Piepkorn, L.; Schmidke, A. M.; Mitkovski, M.; Kannaiyan, N.; Hosang, L.; Scholz, P.; Shaib, A. H. et al.; Schneider, L. V.; Hesse, D.; Ruhwedel, T.; Sun, T.; Linhoff, L.; Trevisiol, A.; Köhler, S.; Pastor, A. M.; Misgeld, T.; Sereda, M.; Hassouna, I.; Rossner, M. J.; Odoardi, F.; Ischebeck, T.; de Hoz, L.; Hirrlinger, J.; Jahn, O.; Saher, G.: Ketogenic diet uncovers differential metabolic plasticity of brain cells. Science Advances 8 (37), eabo7639 (2022)

Hirrlinger, J.; Nimmerjahn, A.: A perspective on astrocyte regulation of neural circuit function and animal behavior. Glia 70 (8), pp. 1554 - 1580 (2022)

Köhler, S.; Winkler, U.; Hirrlinger, J.: Heterogeneity of Astrocytes in Grey and White Matter. Neurochemical Research 46, pp. 3 - 14 (2021)

Trevisiol, A.; Kusch, K.; Steyer, A. M.; Gregor, I.; Nardis, C.; Winkler, U.; Köhler, S.; Restrepo, A.; Möbius, W.; Werner, H. B. et al.; Nave, K.-A.; Hirrlinger, J.: Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia. PLoS Biology 18 (11), e3000943 (2020)

Brebner, L. S.; Ziminski, J. J.; Margetts‐Smith, G.; Sieburg, M. C.; Hall, C. N.; Heintz, T. G.; Lagnado, L.; Hirrlinger, J.; Crombag, H. S.; Koya, E.: Extinction of cue‐evoked food‐seeking recruits a GABAergic interneuron ensemble in the dorsal medial prefrontal cortex of mice. European Journal of Neuroscience 52 (7), pp. 3723 - 3737 (2020)

Natsubori, A.; Tsunematsu, T.; Karashima, A.; Imamura, H.; Kabe, N.; Trevisiol, A.; Hirrlinger, J.; Kodama, T.; Sanagi, T.; Masamoto, K. et al.; Takata, N.; Nave, K.-A.; Matsui, K.; Tanaka, K.F.; Honda, M.: Intracellular ATP levels in mouse cortical excitatory neurons varies with sleep–wake states. Communications Biology 3 (1), 491 (2020)

Brebner, L. S.; Ziminski, J. L.; Margetts-Smith, G.; Sieburg, M. C.; Reeve, H. M.; Nowotny, T.; Hirrlinger, J.; Heintz, T.; Lagnado, L.; Kato, S. et al.; Kobajashi, K.; Ramsey, L. A.; Hall, C.; Crombag, H. S.; Koya, E.: The emergence of a stable neuronal ensemble from a wider pool of activated neurons in the dorsal medial prefrontal cortex during appetitive learning in mice. The Journal of Neuroscience 40 (2), pp. 395 - 410 (2020)

Gerkau, N. J.; Lerchundi, R.; Nelson, J. S. E.; Lantermann, M.; Meyer, J.; Hirrlinger, J.; Rose, C. R.: Relation between activity‐induced intracellular sodium transients and ATP dynamics in mouse hippocampal neurons. The Journal of Physiology 597 (23), pp. 5687 - 5705 (2019)