Publications of M. Zweckstetter

Petroi, D.; Popova, B.; Taheri-Talesh, N.; Irniger, S.; Shapasandzadeh, H.; Zweckstetter, M.; Outeiro, T. F.; Braus, G. H.: Aggregate clearance of α-synuclein in Saccharomyces cerevisiae depends more on autophagosome and vacuole function than on the proteasome. Journal of Biological Chemistry 287 (33), pp. 27567 - 27579 (2012)

Rezaei-Ghaleh, N.; Blackledge, M.; Zweckstetter, M.: Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery. ChemBioChem 13 (7), pp. 930 - 950 (2012)

Taschenberger, G.; Garrido, M.; Tereshchenko, Y.; Baehr, M.; Zweckstetter, M.; Kuegler, S.: Aggregation of alpha Synuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons. Acta Neuropathologica 123 (5), pp. 671 - 683 (2012)

Berger, R.; Courtieu, J.; Gil, R. R.; Griesinger, C.; Köck, M.; Lesot, P.; Luy, B.; Merlet, D.; Navarro-Vazquez, A.; Reggelin, M. et al.; Reinscheid, U. M.; Thiele, C. M.; Zweckstetter, M.: Is enantiomer assignment possible by NMR spectroscopy using residual dipolar couplings from chiral nonracemic alignment media?—A critical assessment. Angewandte Chemie International Edition 51 (33), pp. 8388 - 8391 (2012)

Daebel, V.; Chinnathambi, S.; Biernat, J.; Schwalbe, M.; Habenstein, B.; Loquet, A.; Akoury, E.; Tepper, K.; Mueller, H.; Baldus, M. et al.; Griesinger, C.; Zweckstetter, M.; Mandelkow, E.; Vijayan, V.; Lange, A.: β-sheet core of Tau paired helical filaments revealed by solid-state NMR. Journal of the American Chemical Society 134 (34), pp. 13982 - 13989 (2012)

Ozenne, V.; Schneider, R.; Yao, M.; Huang, J.-R.; Salmon, L.; Zweckstetter, M.; Jensen, M. R.; Blackledge, M.: Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. Journal of the American Chemical Society 134 (36), pp. 15138 - 15148 (2012)

Bibow, S.; Ozenne, V.; Biernat, J.; Blackledge, M.; Mandelkow, E.; Zweckstetter, M.: Structural impact of proline-directed pseudophosphorylation at AT8, AT100, and PHF1 epitopes on 441-residue tau. Journal of the American Chemical Society 133 (40), pp. 15842 - 15845 (2011)

Lamberto, C. R.; Torres-Monserrat, V.; Bertoncini, C. W.; Salvatella, X.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Toward the discovery of effective polycyclic inhibitors of alpha-Synuclein amyloid assembly. Journal of Biological Chemistry 286 (37), pp. 32036 - 32044 (2011)

Balija, M. B. G.; Griesinger, C.; Herzig, A.; Zweckstetter, M.; Jäckle, H.: Pre-fibrillar alpha-Synuclein mutants cause Parkinson's disease-like non-motor symptoms in Drosophila. PLoS One 6 (9), e24701 (2011)

Rezaei-Ghaleh, N.; Giller, K.; Becker, S.; Zweckstetter, M.: Effect of zinc binding on beta-amyloid structure and dynamics: Implications for a beta aggregation. Biophysical Journal 101 (5), pp. 1202 - 1211 (2011)

Luo, L.; Hannemann, M.; Koenig, S.; Hegermann, J.; Ailion, M.; Cho, M. K.; Sasidharan, N.; Zweckstetter, M.; Rensing, S. A.; Eimer, S.: The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology. Molecular Biology of the Cell 22 (14), pp. 2564 - 2578 (2011)

Krumova, P.; Meulmeester, E.; Garrido, M.; Tirard, M.; Hsiao, H. H.; Bossis, G.; Urlaub, H.; Zweckstetter, M.; Kuegler, S.; Melchior, F. et al.; Baehr, M.; Weishaupt, J. H.: Sumoylation inhibits alpha-synuclein aggregation and toxicity. Journal of Cell Biology 194 (1), pp. 49 - 60 (2011)

Kumar, S.; Rezaei-Ghaleh, N.; Terwel, D.; Thal, D. R.; Richard, M.; Hoch, M.; McDonald, J. M.; Wuellner, U.; Glebov, K.; Heneka, M. T. et al.; Walsh, D. M.; Zweckstetter, M.; Walter, J.: Extracellular phosphorylation of the amyloid beta-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. EMBO Journal 30 (11), pp. 2255 - 2265 (2011)

Rezaei-Ghaleh, N.; Andreetto, E.; Yan, L. M.; Kapurniotu, A.; Zweckstetter, M.: Interaction between amyloid beta peptide and an aggregation blocker peptide mimicking islet amyloid polypeptide. PLoS One 6 (5), e20289 (2011)

Cho, M. K.; Kim, H. Y.; Fernandez, C. O.; Becker, S.; Zweckstetter, M.: Conserved core of amyloid fibrils of wild type and A30P mutant alpha-synuclein. Protein Science 20 (2), pp. 387 - 395 (2011)

Binolfi, A.; Valiente-Gabioud, A. A.; Duran, R.; Zweckstetter, M.; Griesinger, C.; Fernandez, C. O.: Exploring the structural details of Cu(I) binding to alpha-synuclein by NMR spectroscopy. Journal of the American Chemical Society 133 (2), pp. 194 - 196 (2011)

Bibow, S.; Mukrasch, M. D.; Chinnathambi, S.; Biernat, J.; Griesinger, C.; Mandelkow, E.; Zweckstetter, M.: The dynamic structure of filamentous tau. Angewandte Chemie-International Edition 50 (48), pp. 11520 - 11524 (2011)

Gruene, T.; Cho, M. K.; Karyagina, I.; Kim, H. Y.; Grosse, C.; Giller, K.; Zweckstetter, M.; Becker, S.: Integrated analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy. Journal of Biomolecular NMR 49 (2), pp. 111 - 119 (2011)

Villinger, S.; Briones, R.; Giller, K.; Zachariä, U.; Lange, A.; de Groot, B. L.; Griesinger, C.; Becker, S.; Zweckstetter, M.: Functional dynamics in the voltage-dependent anion channel. Proceedings of the National Academy of Sciences of the United States of America 107 (52), pp. 22546 - 22551 (2010)

Binolfi, A.; Rodriguez, E. E.; Valensin, D.; D'Amelio, N.; Ippoliti, E.; Obal, G.; Duran, R.; Magistrato, A.; Pritsch, O.; Zweckstetter, M. et al.; Valensin, G.; Carloni, P.; Quintanar, L.; Griesinger, C.; Fernandez, C. O.: Bioinorganic chemistry of Parkinson's disease: Structural determinants for the copper-mediated amyloid formation of Alpha-Synuclein. Inorganic Chemistry 49 (22), pp. 10668 - 10679 (2010)