Publications

Journal Article (34)

1.
Journal Article
Mercier, E.; Wang, X.; Maiti, M.; Wintermeyer, W.; Rodnina, M. V.: Lateral gate dynamics of the bacterial translocon during cotranslational membrane protein insertion. Proceedings of the National Academy of Sciences of the USA 118 (26), e2100474118 (2021)
2.
Journal Article
Mercier, E.; Wintermeyer, W.; Rodnina, M. V.: Co‐translational insertion and topogenesis of bacterial membrane proteins monitored in real time. EMBO Journal 39 (15), e104054 (2020)
3.
Journal Article
Rodnina, M. V.; Peske, F.; Peng, B. Z.; Belardinelli, R.; Wintermeyer, W.: Converting GTP hydrolysis into motion: Versatile translational elongation factor G. Biological Chemistry 401 (1), pp. 131 - 142 (2019)
4.
Journal Article
Zaghouania, M.; Bögeholz, L. A. K.; Mercier, E.; Wintermeyer, W.; Roche, S. P.: Total synthesis of (±)-fumimycin and analogues for biological evaluation as peptide deformylase inhibitors. Tetrahedron 75 (24), pp. 3216 - 3230 (2019)
5.
Journal Article
Draycheva, A.; Lee, S.; Wintermeyer, W.: Cotranslational protein targeting to the membrane: Nascent-chain transfer in a quaternary complex formed at the translocon. Scientific Reports 8 (1), 9922 (2018)
6.
Journal Article
Mercier, E.; Holtkamp, W.; Rodnina, M. V.; Wintermeyer, W.: Signal recognition particle binds to translating ribosomes before emergence of a signal anchor sequence. Nucleic Acids Research 45 (20), pp. 11858 - 11866 (2017)
7.
Journal Article
Ranjan, A.; Mercier, E.; Bhatt, A.; Wintermeyer, W.: Signal recognition particle prevents N-terminal processing of bacterial membrane proteins. Nature Communications 8, 15562 (2017)
8.
Journal Article
Draycheva, A.; Bornemann, T.; Ryazanov, S.; Lakomek, N. A.; Wintermeyer, W.: The bacterial SRP receptor, FtsY, is activated on binding to the translocon. Molecular Microbiology 102 (1), pp. 152 - 167 (2016)
9.
Journal Article
Lakomek, N. A.; Draycheva, A.; Bornemann, T.; Wintermeyer, W.: Electrostatics and intrinsic disorder drive translocon binding of the SRP receptor FtsY. Angewandte Chemie International Edition 55 (33), pp. 9544 - 9547 (2016)
10.
Journal Article
Rodnina, M. V.; Wintermeyer, W.: Protein elongation, co-translational folding and targeting. Journal of Molecular Biology 428 (10, P. B), pp. 2165 - 2185 (2016)
11.
Journal Article
Belardinelli, R.; Sharma, H.; Caliskan, N.; da Cunha, C. E. L.; Peske, F.; Wintermeyer, W.; Rodnina, M. V.: Choreography of molecular movements during ribosome progression along mRNA. Nature Structural and Molecular Biology 23 (4), pp. 342 - 348 (2016)
12.
Journal Article
Belardinelli, R.; Sharma, H.; Peske, F.; Wintermeyer, W.; Rodnina, M. V.: Translocation as continuous movement through the ribosome. RNA Biology 13 (12), pp. 1197 - 1203 (2016)
13.
Journal Article
Kuhn, P.; Draycheva, A.; Vogt, A.; Petriman, N. A.; Sturm, L.; Drepper, F.; Warscheid, B.; Wintermeyer, W.; Koch, H. G.: Ribosome binding induces repositioning of the signal recognition particle receptor on the translocon. Journal of Cell Biology 211 (1), pp. 91 - 104 (2015)
14.
Journal Article
Adio, S.; Senyushkina, T.; Peske, F.; Fischer, N.; Wintermeyer, W.; Rodnina, M. V.: Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome. Nature Communications 6, 7442 (2015)
15.
Journal Article
Ge, Y.; Draycheva, A.; Bornemann, T.; Rodnina, M. V.; Wintermeyer, W.: Lateral opening of the bacterial translocon on ribosome binding and signal peptide insertion. Nature Communications 5, 5263 (2014)
16.
Journal Article
Holtkamp, W.; Wintermeyer, W.; Rodnina, M. V.: Synchronous tRNA movements during translocation on the ribosome are orchestrated by elongation factor G and GTP hydrolysis. BioEssays 36 (10), pp. 908 - 918 (2014)
17.
Journal Article
Bornemann, T.; Holtkamp, W.; Wintermeyer, W.: Interplay between trigger factor and other protein biogenesis factors on the ribosome. Nature Communications 5, 4180 (2014)
18.
Journal Article
Holtkamp, W.; da Cunha, C. E. L.; Peske, F.; Konevega, A. L.; Wintermeyer, W.; Rodnina, M. V.: GTP hydrolysis by EF‐G synchronizes tRNA movement on small and large ribosomal subunits. EMBO Journal 33 (9), pp. 1073 - 1085 (2014)
19.
Journal Article
Peske, F.; Kuhlenkötter, S.; Rodnina, M. V.; Wintermeyer, W.: Timing of GTP binding and hydrolysis by translation termination factor RF3. Nucleic Acids Research 42 (3), pp. 1812 - 1820 (2014)
20.
Journal Article
da Cunha, C. E. L.; Belardinelli, R.; Peske, F.; Holtkamp, W.; Wintermeyer, W.; Rodnina, M. V.: Dual use of GTP hydrolysis by elongation factor G on the ribosome. Translation 1 (1), e24315 (2013)
21.
Journal Article
Holtkamp, W.; Lee, S.; Bornemann, T.; Senyushkina, T.; Rodnina, M. V.; Wintermeyer, W.: Dynamic switch of the signal recognition particle from scanning to targeting. Nature Structural and Molecular Biology 19 (12), pp. 1332 - 1337 (2012)
22.
Journal Article
Cox, G.; Thompson, G. S.; Jenkins, H. T.; Peske, F.; Savelsbergh, A.; Rodnina, M. V.; Wintermeyer, W.; Homans, S. W.; Edwards, T. A.; O'Neill, A. J.: Ribosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid. Proceedings of the National Academy of Sciences of the United States of America 109 (6), pp. 2102 - 2107 (2012)
23.
Journal Article
Kuhlenkötter, S.; Wintermeyer, W.; Rodnina, M. V.: Different substrate-dependent transition states in the active site of the ribosome. Nature 476, pp. 351 - 354 (2011)
24.
Journal Article
Rodnina, M. V.; Wintermeyer, W.: The ribosome as a molecular machine: The mechanism of tRNA–mRNA movement in translocation. Biochemical Society Transactions 39, pp. 658 - 662 (2011)
25.
Journal Article
Wintermeyer, W.; Rodnina, M. V.: Genauigkeit und Geschwindigkeit der Proteinsynthese. Biospektrum 17 (4), pp. 389 - 392 (2011)
26.
Journal Article
Milon, P.; Carotti, M.; Konevega, A. L.; Wintermeyer, W.; Rodnina, M. V.; Gualerzi, C. O.: The ribosome-bound initiation factor 2 recruits initiator tRNA to the 30S initiation complex. EMBO Reports 11 (4), pp. 312 - 316 (2010)
27.
Journal Article
Fischer, N.; Konevega, A. L.; Wintermeyer, W.; Rodnina, M. V.; Stark, H.: Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy. Nature 466 (7304), pp. 329 - 333 (2010)
28.
Journal Article
Rodnina, M. V.; Wintermeyer, W.: The ribosome goes Nobel. Trends in Biochemical Sciences 35 (1), pp. 1 - 5 (2010)
29.
Journal Article
Rodnina, M. V.; Wintermeyer, W.: Recent mechanistic insight into eukaryotic ribosomes. Current Opinion in Cell Biology 21 (3), pp. 435 - 443 (2009)
30.
Journal Article
Savelsbergh, A.; Rodnina, M. V.; Wintermeyer, W.: Distinct functions of elongation factor G in ribosome recycling and translocation. RNA 15 (5), pp. 772 - 780 (2009)
31.
Journal Article
Buskiewicz, I. A.; Jöckel, J.; Rodnina, M. V.; Wintermeyer, W.: Conformation of the signal recognition particle in ribosomal targeting complexes. RNA 15 (1), pp. 44 - 54 (2009)
32.
Journal Article
Rodnina, M. V.; Wintermeyer, W.: Das Ribosom: Struktur und Funktionen eines Mega-Ribozyms. Biospektrum 9 (2), pp. 138 - 141 (2003)
33.
Journal Article
Stark, H.; Rodnina, M. V.; Wieden, H. J.; Zemlin, F.; Wintermeyer, W.; van Heel, M.: Ribosome interactions of aminoacyl-tRNA and elongation factor Tu in the codon-recognition complex. Nature Structural Biology 9 (11), pp. 849 - 854 (2002)
34.
Journal Article
Stark, H.; Rodnina, M. V.; Wieden, H. J.; Zemlin, F.; Wintermeyer, W.; van Heel, M.: Ribosome interactions of aminoacyl-tRNA and elongation factor Tu in the codon-recognition complex. Nature Structural Biology 9 (11), pp. 849 - 854 (2002)

Book (1)

35.
Book
Rodnina, M.; Wintermeyer, W.; Green, R. (Eds.): Ribosomes: Structure, Function, and Dynamics. Springer, Wien (2011), IX, 442 pp.

Book Chapter (5)

36.
Book Chapter
Bornemann, T.; Holtkamp, W.; Wintermeyer, W.: Nascent peptide-induced signaling from the exit tunnel to the outside of the ribosome. In: Regulatory nascent polypeptides, pp. 87 - 97 (Ed. Ito, K.). Springer, Tokyo (2014)
37.
Book Chapter
Peske, F.; Wintermeyer, W.: Antibiotics inhibiting the translocation step of protein elongation on the ribosome. In: Antibiotics: Targets, Mechanisms and Resistance, pp. 491 - 508 (Eds. Gualerzi, C. O.; Brandi, L.; Fabbretti, A.; Pon, C. L.). Wiley VCH, Weinheim (2013)
38.
Book Chapter
Rodnina, M. V.; Wintermeyer, W.: Rapid kinetic analysis of protein synthesis. In: Biophysical approaches to translational control of gene expression, pp. 119 - 139 (Ed. Dinman, J. D.). Springer, New York (2013)
39.
Book Chapter
Wintermeyer, W.: Translocation on the ribosome. In: Encyclopedia of biophysics, Vol. 5; S - Z, pp. 2650 - 2655 (Ed. Roberts, G. C. K.). Springer, Heidelberg (2013)
40.
Book Chapter
Wintermeyer, W.; Savelsbergh, A.; Konevega, A. L.; Peske, F.; Katunin, V.; Semenkov, Y.; Fischer, N.; Stark, H.; Rodnina, M.: Functions of elongation factor G in translocation and ribosome recycling. In: Ribosomes: Structure, Function, and Dynamics, pp. 329 - 338. Springer, Wien (2011)
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