Publications of H. J. Eibl

Limmer, S.; Hahn, J.; Schmidt, R.; Wachholz, K.; Zengerle, A.; Lechner, K.; Eibl, H. J.; Issels, R. D.; Hossann, M.; Lindner, L. H.: Gemcitabine treatment of rat soft tissue sarcoma with phosphatidyldiglycerol-based thermosensitive liposomes. Pharmaceutical Research 31 (9), pp. 2276 - 2286 (2014)

Rudner, J.; Ruiner, C. E.; Handrick, R.; Eibl, H. J.; Belka, C.; Jendrossek, V.: The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation. Radiation Oncology 5, 108 (2010)

Hossann, M.; Wang, T. T.; Wiggenhorn, M.; Schmidt, R.; Zengerle, A.; Winter, G.; Eibl, H. J.; Peller, M.; Reiser, M.; Issels, R. D. et al.; Lindner, L. H.: Size of thermosensitive liposomes influences content release. Journal of Controlled Release 147 (3), pp. 436 - 443 (2010)

Koenigs, S. K.; Pallasch, C. P.; Lindner, L. H.; Schwamb, J.; Schulz, A.; Brinker, R.; Claasen, J.; Veldurthy, A.; Eibl, H. J.; Hallek, M. et al.; Wendtner, C. M.: Erufosine, a novel alkylphosphocholine, induces apoptosis in CLL through a caspase-dependent pathway. Leukemia Research: Interdisciplinary International 34 (8), pp. 1064 - 1069 (2010)

Martelli, A. M.; Papa, V.; Tazzari, P. L.; Ricci, F.; Evangelisti, C.; Chiarini, F.; Grimaldi, C.; Cappellini, A.; Martinelli, G.; Ottaviani, E. et al.; Pagliaro, P.; Horn, S.; Baesecke, J.; Lindner, L. H.; Eibl, H. J.; McCubrey, J. A.: Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms. Leukemia: the Journal of Normal and Malignant Hemopoiese ; Official Journal of the Leukemia Research Fund U.K. 24 (4), pp. 687 - 698 (2010)

Henke, G.; Lindner, L. H.; Vogeser, M.; Eibl, H. J.; Woerner, J.; Mueller, A. C.; Bamberg, M.; Wachholz, K.; Belka, C.; Jendrossek, V.: Pharmacokinetics and biodistribution of Erufosine in nude mice - implications for combination with radiotherapy. Radiation Oncology 4 (1), 46 (2009)

Fiegl, M.; Lindner, L. H.; Juergens, M.; Eibl, H.; Hiddemann, W.; Braess, J.: Erufosine, a novel alkylphosphocholine, in acute myeloid leukemia: single activity and combination with other antileukemic drugs. Cancer Chemotherapy and Pharmacology 62 (2), pp. 321 - 329 (2008)

Lindner, L. H.; Eibl, H.; Hossann, M.; Vogeser, M.: Quantification of erufosine, the first intravenously applicable alkylphosphocholine, in human plasma by isotope dilution liquid chromatography–tandem mass spectrometry using a deuterated internal standard. Journal of Chromatography B 869 (1-2), pp. 16 - 19 (2008)

Lindner, L. H.; Hossann, M.; Vogeser, M.; Teichert, N.; Wachholz, K.; Eibl, H.; Hiddemann, W.; Issels, R.D.: Dual role of hexadecylphosphocholine (miltefosine) in thermosensitive liposomes: Active ingredient and mediator of drug release. Journal of Controlled Release 125 (2), pp. 112 - 120 (2008)

Wang, T.; Hossann, M.; Reinl, H. M.; Peller, M.; Eibl, H.; Reiser, M.; Issels, R. D.; Lindner, L. H.: In vitro characterization of phosphatidylglyceroglycerol-based thermosensitive liposomes with encapsulated H-1 MR T-1-shortening gadodiamide. Contrast Media and Molecular Imaging 3 (1), pp. 19 - 26 (2008)

Hossann, M.; Wiggenhorn, M.; Schwerdt, A.; Wachholz, K.; Teichert, N.; Eibl, H.; Issels, R. D.; Lindner, L. H.: In vitro stability and content release properties of phosphatidylglyceroglycerol containing thermosensitive liposomes. Biochimica et Biophysica Acta-Biomembranes 1768 (10), pp. 2491 - 2499 (2007)

Goebel, W.; Obermeyer, N.; Bleicher, N.; Kratzmeier, M.; Eibl, H.; Doenecke, D.; Albig, W.: Apoptotic DNA fragmentation is not related to the phosphorylation state of histone H1. Biological Chemistry 388 (2), pp. 197 - 206 (2007)

Handrick, R.; Ruebel, A.; Faltin, H.; Eibl, H.; Belka, C.; Jendrossek, V.: Increased cytotoxicity of ionizing radiation in combination with membrane-targeted apoptosis modulators involves downregulation of protein kinase B/Akt-mediated survival-signaling. Radiotherapy and Oncology 80 (2), pp. 199 - 206 (2006)

Lindner, L. H.; Brock, R.; Arndt-Jovin, D. J.; Eibl, H.: Structural variation of cationic lipids: minimum requirement for improved oligonucleotide delivery into cells. Journal of Controlled Release 110 (2), 10.1016/j.jconrel.2005.10.009, pp. 444 - 456 (2006)

Kugler, W.; Buchholz, F.; Koehler, F.; Eibl, H.; Lakomek, M.; Erdlenbruch, B.: Downregulation of Apaf-1 and caspase-3 by RNA interference in human glioma cells: Consequences for erucylphosphocholine-induced apoptosis. Apoptosis 10 (5), pp. 1163 - 1174 (2005)

Handrick, R.; Rudner, J.; Mueller, I.; Eibl, H.; Belka, C.; Jendrossek, V.: Bcl-2 mediated inhibition of erucylphosphocholine-induced apoptosis depends on its subcellular localisation. Biochemical Pharmacology 70 (6), pp. 837 - 850 (2005)

Erdlenbruch, B.; Kugler, W.; Schinkhof, C.; Neurath, H.; Eibl, H.; Lakomek, M.: Blood-brain barrier opening with alkylglycerols: Biodistribution of 1-O-pentylglycerol after intravenous and intracarotid administration in rats. Journal of Drug Targeting 13 (3), pp. 143 - 150 (2005)

Kugler, W.; Erdlenbruch, B.; Otten, K.; Jendrossek, V.; Eibl, H.; Lakomek, M.: MAP kinase pathways involved in glioblastoma response to erucylphosphocholine. International Journal of Oncology 25 (6), pp. 1721 - 1727 (2004)

Sindermann, H.; Croft, S. L.; Engel, K. R.; Bommer, W.; Eibl, H.; Unger, C.; Engel, J.: Miltefosine (Impavido): the first oral treatment against leishmaniasis. Medical Microbiology and Immunology 193 (4), pp. 173 - 180 (2004)

Lehnert, R.; Eibl, H.; Mueller, K.: Order and dynamics in lipid bilayers from 1,2-dipalmitoyl-sn-glycero-phospho-diglycerol as studied by NMR spectroscopy. Journal of Physical Chemistry B 108 (32), pp. 12141 - 12150 (2004)