Publications of P. Collombat

Collombat, P.; Xiaobo, X.; Heimberg, H.; Mansouri, A.: Pancreatic beta-cells: From generation to regeneration. Seminars in Cell and Developmental Biology 21 (8), pp. 838 - 844 (2010)

Collombat, P.; Mansouri, A.: Turning on the β-cell identity in the pancreas. Cell Cycle 8 (21), pp. 3450 - 3451 (2009)

Colasante, G.; Sessa, A.; Crispi, S.; Calogero, R.; Consalez, G. G.; Mansouri, A.; Collombat, P.; Broccoli, V.: Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity. Developmental Biolology 334 (1), pp. 59 - 71 (2009)

Collombat, P.; Mansouri, A.: Pax4 transdifferentiates glucagon-secreting alpha cells to insulin-secreting beta endocrine pancreatic cells. Medecines Sciences 25 (8-9), pp. 763 - 766 (2009)

Collombat, P.; Xu, X.; Ravassard, P.; Sosa-Pineda, B.; Dussaud, S.; Billestrup, N.; Madsen, O. D.; Serup, P.; Heimberg, H.; Mansouri, A.: The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into α and subsequently β cells. Cell 138 (3), pp. 449 - 462 (2009)

Colasante, G.; Collombat, P.; Raimondi, V.; Bonanomi, D.; Ferrai, C.; Maira, M.; Yoshikawa, K.; Mansouri, A.; Valtorta, F.; Rubenstein, J. L. R. et al.; Broccoli, V.: Arx is a direct target of Dlx2 and thereby contributes to the tangential migration of GABAergic interneurons. The Journal of Neuroscience 28 (42), pp. 10674 - 10686 (2008)

Biressi, S.; Messina, G.; Collombat, P.; Tagliafico, E.; Monteverde, S.; Benedetti, L.; Cusella de Angelis, M. G.; Mansouri, A.; Ferrari, S.; Tajbakhsh, S. et al.; Broccoli, V.; Cossu, G.: The homeobox gene Arx is a novel positive regulator of embryonic myogenesis. Cell Death and Differentiation 15, pp. 94 - 104 (2008)

Wang, Q.; Elghazi, L.; Martin, S.; Martins, I.; Srinivasan, R. S.; Geng, X.; Sleeman, M.; Collombat, P.; Houghton, J.; Sosa-Pineda, B.: Ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum. Developmental Dynamics 237 (1), pp. 51 - 61 (2008)

Colombo, E.; Collombat, P.; Colasante, G.; Bianchi, M.; Long, J.; Mansouri, A.; Rubenstein, J.; Broccoli, V.: Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation. The Journal of Neuroscience 27 (17), pp. 4786 - 4798 (2007)

Collombat, P.; Hecksher-Soerensen, J.; Krull, J.; Berger, J.; Riedel, D.; Herrera, P.; Serup, P.; Mansouri, A.: Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression. The Journal of Clinical Investigation 117 (4), pp. 961 - 970 (2007)

Collombat, P.; Hecksher-Soerensen, J.; Serup, P.; Mansouri, A.: Specifying pancreatic endocrine cell fates. Mechanisms of Development 123 (7), pp. 501 - 512 (2006)

Mellitzer, G.; Bonne, S.; Luco, R. F.; Van De Casteele, M.; Lenne-Samuel, N.; Collombat, P.; Mansouri, A.; Lee, J.; Lan, M.; Pipeleers, D. et al.; Nielsen, F. C.; Ferrer, J.; Gradwohl, G.; Heimberg, H.: IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas. EMBO Journal 25 (6), pp. 1344 - 1352 (2006)

Heller, R. S.; Jenny, M.; Collombat, P.; Mansouri, A.; Tomasetto, C.; Madsen, O. D.; Mellitzer, G.; Gradwohl, G.; Serup, P.: Genetic determinants of pancreatic epsilon-cell development. Developmental Biology 286 (1), pp. 217 - 224 (2005)

Collombat, P.; Hecksher-Soerensen, J.; Broccoli, V.; Krull, J.; Ponte, I.; Mundiger, T.; Smith, J.; Gruss, P.; Serup, P.; Mansouri, A.: The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas. Development 132 (13), pp. 2969 - 2980 (2005)

Schindehuette, J.; Fukumitsu, H.; Collombat, P.; Griesel, G.; Brink, C.; Baier, P. C.; Capecchi, M. R.; Mansouri, A.: In vivo and in vitro tissue-specific expression of green fluorescent protein using the cre-lox system in mouse embryonic stem cells. Stem Cells 23 (1), pp. 10 - 15 (2005)

Collombat, P.; Mansouri, A.: New insights into endocrine pancreas morphogenesis: How to learn from development to better understand pancreatic cancers. Recent Research Developments in Cancer 6, pp. 89 - 109 (2004)

Collombat, P.; Mansouri, A.; Hecksher-Soerensen, J.; Serup, P.; Krull, J.; Gradwohl, G.; Gruss, P.: Opposing actions of Arx and Pax4 in endocrine pancreas development. Genes & Development 17 (20), pp. 2591 - 2603 (2003)

Collombat, P.: Functional characterization of the role of Arx and Pax4 during the development of the endocrine pancreas. Dissertation, Université Paul Sabatier, Toulouse (2004)