Publications of J. Soerensen

Schonn, J. S.; van Weering, J. R.; Mohrmann, R.; Schlueter, O. M.; Suedhof, T. C.; de Wit, H.; Verhage, M.; Soerensen, J.: Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells. Traffic 11 (11), pp. 1415 - 1428 (2010)

Wiederhold, K.; Klöpper, T. H.; Walter, A. M.; Stein, A.; Kienle, N.; Sörensen, J. B.; Fasshauer, D.: A coiled coil trigger site is essential for rapid binding of synaptobrevin to the SNARE acceptor complex. Journal of Biological Chemistry 285 (28), pp. 21549 - 21559 (2010)

Weber, J. P.; Reim, K.; Sörensen, J. B.: Opposing functions of two sub-domains of the SNARE-complex in neurotransmission. The EMBO Journal 29 (15), pp. 2477 - 2490 (2010)

Walter, A. M.; Wiederhold, K.; Bruns, D.; Fasshauer, D.; Soerensen, J. B.: Synaptobrevin N-terminally bound to syntaxin–SNAP-25 defines the primed vesicle state in regulated exocytosis. The Journal of Cell Biology 188 (3), pp. 401 - 413 (2010)

de Wit, H.; Walter, A. M.; Milosevic, I.; Gulyas-Kovacs, A.; Riedel, D.; Soerensen, J. B.; Verhage, M.: Synaptotagmin-1 docks secretory vesicles to syntaxin-1/SNAP-25 acceptor complexes. Cell 138 (5), pp. 935 - 946 (2009)

Cai, H.; Reim, K.; Varoqueaux, F.; Tapechum, S.; Hill, K.; Soerensen, J. B.; Brose, N.; Chow, R. H.: Complexin II plays a positive role in Ca²⁺-triggered exocytosis by facilitating vesicle priming. Proceedings of the National Academy of Sciences of the United States of America 105 (49), pp. 19538 - 19543 (2008)

Fang, Q.; Berberian, K.; Gong, L. W.; Hafez, I.; Soerensen, J. B.; Lindau, M.: The role of the C terminus of the SNARE protein SNAP-25 in fusion pore opening and a model for fusion pore mechanics. Proceedings of the National Academy of Sciences of the United States of America 105 (40), pp. 15388 - 15392 (2008)

Fang, Q.; Berberian, K.; Gong, L. W.; Hafez, I.; Soerensen, J. B.; Lindau, M.: The role of the C terminus of the SNARE protein SNAP-25 in fusion pore opening and a model for fusion pore mechanics. Proceedings of the National Academy of Sciences of the United States of America 105 (40), pp. 15388 - 15392 (2008)

Nagy, G.; Milosevic, I.; Mohrmann, R.; Wiederhold, K.; Walter, A. M.; Soerensen, J. B.: The SNAP-25 linker as an adaptation toward fast exocytosis. Molecular Biology of the Cell 19 (9), pp. 3769 - 3781 (2008)

Verhage, M.; Soerensen, J. B.: Vesicle docking in regulated exocytosis. Traffic 9, pp. 1414 - 1424 (2008)

Maximov, A.; Lao, Y.; Li, H.; Chen, X.; Rizo, J.; Soerensen, J. B.; Suedhof, T. C.: Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis. Proceedings of the National Academy of Sciences of the United States of America 105 (10), pp. 3986 - 3991 (2008)

Jokusch, W. J.; Speidel, D.; Sigler, A.; Soerensen, J. B.; Varoqueaux, F.; Rhee, J. S.; Brose, N.: CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins. Cell 131 (4), pp. 796 - 808 (2007)

Delgado-Martinez, I.; Nehring, R. B.; Soerensen, J. B.: Differential abilities of SNAP-25 homologs to support neuronal function. The Journal of Neuroscience 27 (35), pp. 9380 - 9391 (2007)

Gulyas-Kovacs, A.; de Wit, H.; Milosevic, I.; Kochubey, O.; Toonen, R.; Klingauf, J.; Verhage, M.; Soerensen, J. B.: Munc18-1: Sequential interactions with the fusion machinery stimulate vesicle docking and priming. Journal of Neuroscience 27 (32), pp. 8676 - 8686 (2007)

Nili, U.; de Wit, H.; Gulyas-Kovacs, A.; Toonen, R. F.; Soerensen, J. B.; Verhage, M.; Ashery, U.: Munc18-1 phosphorylation by protein kinase C potentiates vesicle pool replenishment in bovine chromaffin cells. Neuroscience 143 (2), pp. 487 - 500 (2006)

Zilly, F.; Soerensen, J. B.; Jahn, R.; Lang, T.: Munc18-bound syntaxin readily forms SNARE complexes with synaptobrevin in native plasma membranes. PLoS Biology 4 (10), e330, pp. 1789 - 1797 (2006)

Toonen, R. F.; Kochubey, O.; de Wit, H.; Gulyas-Kovacs, A.; Konijnenburg, B.; Soerensen, J. B.; Klingauf, J.; Verhage, M.: Dissecting docking and tethering of secretory vesicles at the target membrane. EMBO Journal 25 (16), pp. 3725 - 3737 (2006)

Nagy, G.; Kim, J. H.; Pang, Z. P.; Matti, U.; Rettig, J.; Suedhof, T. C.; Soerensen, J. B.: Different effects on fast exocytosis induced by synaptotagmin 1 and 2 isoforms and abundance but not by phosphorylation. Journal of Neuroscience 26 (2), pp. 632 - 643 (2006)

Soerensen, J. B.; Wiederhold, K.; Mueller, E. M.; Milosevic, I.; Nagy, G.; de Groot, B. L.; Grubmueller, H.; Fasshauer, D.: Sequential N-to C-terminal SNARE complex assembly drives priming and fusion of secretory vesicles. EMBO Journal 25, pp. 955 - 966 (2006)

Nagy, G.; Milosevic, I.; Fasshauer, D.; Mueller, E. M.; de Groot, B. L.; Lang, T.; Wilson, M. C.; Soerensen, J. B.: Alternative splicing of SNAP-25 regulates secretion through nonconservative substitutions in the SNARE domain. Molecular Biology of the Cell 16 (12), pp. 5675 - 5685 (2005)