Publications
Journal Article (34)
1.
Journal Article
16, 1033 (2025)
The α-globin super-enhancer acts in an orientation-dependent manner. Nature Communications 2.
Journal Article
85 (2), pp. 199 - 201 (2025)
Bridging the gap: How enhancers cooperate to regulate gene expression over large genomic distances. Molecular Cell 3.
Journal Article
15, 9918 (2024)
Genome-wide profiling of DNA repair proteins in single cells. Nature Communications 4.
Journal Article
89, 102398 (2024)
The relationship between nucleosome positioning and higher-order genome folding. Current Opinion in Cell Biology 5.
Journal Article
84 (11), pp. 2053 - 2069.e9 (2024)
FACT maintains chromatin architecture and thereby stimulates RNA polymerase II pausing during transcription in vivo. Molecular Cell 6.
Journal Article
56, pp. 483 - 492 (2024)
In vitro reconstitution of chromatin domains shows a role for nucleosome positioning in 3D genome organization. Nature Genetics 7.
Journal Article
52 (2), pp. 793 - 802 (2024)
Genome organization across scales: mechanistic insights from in vitro reconstitution studies. Biochemical Society Transactions 8.
Journal Article
30 (7), pp. 876 - 877 (2023)
The Mediator complex regulates long-range communication in the genome. Nature Structural & Molecular Biology 9.
Journal Article
30, pp. 991 - 1000 (2023)
The Mediator complex regulates enhancer-promoter interactions. Nature Structural and Molecular Biology 10.
Journal Article
79, 102022 (2023)
The role of loop extrusion in enhancer-mediated gene activation. Current Opinion in Genetics & Development 11.
Journal Article
54 (7), pp. 914 - 915 (2022)
Deciphering the regulatory logic of a chromatin domain boundary. Nature Genetics 12.
Journal Article
13, 2139 (2022)
Analysis of sub-kilobase chromatin topology reveals nano-scale regulatory interactions with variable dependence on cohesin and CTCF. Nature Communications 13.
Journal Article
17 (2), pp. 445 - 475 (2022)
Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture. Nature Protocols 14.
Journal Article
13, 773 (2022)
Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development. Nature Communications 15.
Journal Article
12, 4439 (2021)
Reactivation of a developmentally silenced embryonic globin gene. Nature Communications 16.
Journal Article
595 (7865), pp. 125 - 129 (2021)
Defining genome architecture at base-pair resolution. Nature 17.
Journal Article
12, 3806 (2021)
A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker. Nature Communications 18.
Journal Article
67, pp. 18 - 24 (2021)
The mouse alpha-globin cluster: A paradigm for studying genome regulation and organization. Current Opinion in Genetics & Development 19.
Journal Article
81 (5), pp. 983 - 997.e7 (2021)
Enhancers predominantly regulate gene expression during differentiation via transcription initiation. Molecular Cell 20.
Journal Article
22, pp. 154 - 168 (2021)
The relationship between genome structure and function. Nature Reviews Genetics 21.
Journal Article
12, 531 (2021)
High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale. Nature Communications 22.
Journal Article
17 (11), pp. 1118 - 1124 (2020)
DeepC: predicting 3D genome folding using megabase-scale transfer learning. Nature Methods 23.
Journal Article
11, 2722 (2020)
Dynamics of the 4D genome during in vivo lineage specification and differentiation. Nature Communications 24.
Journal Article
30 (7), pp. 2125 - 2135.e1-e5 (2020)
A dynamic folded hairpin conformation is associated with α-globin activation in erythroid cells. Cell Reports 25.
Journal Article
10, 5412 (2019)
A revised model for promoter competition based on multi-way chromatin interactions at the α-globin locus. Nature Communications 26.
Journal Article
10, 2803 (2019)
DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation. Nature Communications 27.
Journal Article
50 (12), pp. 1744 - 1751 (2018)
Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains. Nature Genetics 28.
Journal Article
9, 3849 (2018)
A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions. Nature Communications 29.
Journal Article
45 (22), e184 (2017)
Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C. Nucleic Acids Research 30.
Journal Article
7 (23), e2645 (2017)
Low-input Capture-C: A chromosome conformation capture assay to analyze chromatin architecture in small numbers of cells. Bio-protocol 31.
Journal Article
26 (R2), pp. R208 - R215 (2017)
Between form and function: the complexity of genome folding. Human Molecular Genetics 32.
Journal Article
19 (8), pp. 952 - 961 (2017)
Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo. Nature Cell Biology 33.
Journal Article
14 (2), pp. 125 - 134 (2017)
How best to identify chromosomal interactions: A comparison of approaches. Nature Methods 34.
Journal Article
48 (8), pp. 895 - 903 (2016)
Genetic dissection of the α-globin super-enhancer in vivo. Nature Genetics Book Chapter (1)
35.
Book Chapter
Assessment of multiway interactions with Tri-C. In: Spatial Genome Organization, pp. 95 - 112 (Ed. Sexton, T.). Humana Pr., Springer, New York, NY (2022)