Publications of J. Harborth

Hinrichsen, L.; Harborth, J.; Andrees, L.; Weber, K.; Ungewickell, E.: Effect of clathrin heavy chain- and alpha-adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in HeLa cells. Journal of Biological Chemistry 278 (46), pp. 45160 - 45170 (2003)

Harborth, J.; Elbashir, S. M.; Vandenburgh, K.; Manninga, H.; Scaringe, S. A.; Weber, K.; Tuschl, T.: Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing. Antisense & Nucleic Acid Drug Development 13 (2), pp. 83 - 105 (2003)

Gruber, J.; Harborth, J.; Schnabel, J.; Weber, K.; Hatzfeld, M.: The mitotic-spindle-associated protein astrin is essential for progression through mitosis. Journal of Cell Science 115 (21), pp. 4053 - 4059 (2002)

Elbashir, S. M.; Harborth, J.; Weber, K.; Tuschl, T.: Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26 (2), pp. 199 - 213 (2002)

Harborth, J.; Elbashir, S. M.; Bechert, K.; Tuschl, T.; Weber, K.: RNAi based gene silencing in mammalian tissue culture cells: a key procedure fur functional gone analysis. Molecular Biology of the Cell 12 (Suppl. S), p. 2866 (2001)

Karabinos, A.; Schmidt, H.; Harborth, J.; Schnabel, R.; Weber, K.: Essential roles for four cytoplasmic intermediate filament proteins in Caenorhabditis elegans development. Proceedings of the National Academy of Scienes of the United States of America 98 (14), pp. 7863 - 7868 (2001)

Elbashir, S. M.; Harborth, J.; Lendeckel, W.; Yalcin, A.; Weber, K.; Tuschl, T.: Duplexes of 21-nucleotide RNAs mediate RNA interference in mammalian cell culture. Nature 411, pp. 494 - 498 (2001)

Harborth, J.; Elbashir, S. M.; Bechert, K.; Tuschl, T.; Weber, K.: Identification of essential genes in cultured mammalian cells using small interfering RNAs. Journal of Cell Science 114, pp. 4557 - 4565 (2001)

Harborth, J.; Weber, K.; Osborn, M.: GAS 41, a highly conserved protein in eukaryotic nuclei, binds to NuMA. Journal of Biological Chemistry 275, pp. 31979 - 31985 (2000)

Harborth, J.; Osborn, M.: Does NuMa have a scaffold function in the interphase nucleus. Critical Reviews in Eukaryotic Gene Expression 9 (3-4), pp. 319 - 328 (1999)

Harborth, J.; Wang, J.; Gueth-Hallonet, C.; Weber, K.; Osborn, M.: Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice. EMBO Journal 18, pp. 1689 - 1700 (1999)

Gueth-Hallonet, C.; Wang, J.; Harborth, J.; Weber, K.; Osborn, M.: Induction of a regular nuclear lattice by overexpression of NuMA. Experimental Cell Research 243, pp. 434 - 452 (1998)

Butschak, G.; Harborth, J.; Osborn, M.; Karsten, U.: New monoclonal antibodies recognizing phosphorylated proteins in mitotic cells. Acta Histochemica 97 (1), pp. 19 - 31 (1995)

Kallajoki, M.; Harborth, J.; Weber, K.; Osborn, M.: Microinjection of a monoclonal antibody against SPN antigen, now identified by peptide sequences as the NuMA protein, induces micronuclei in PtK2 cells. Journal of Cell Science 104, pp. 139 - 150 (1993)