Publications of R. Luehrmann

Martinez, J.; Patkaniowska, A.; Urlaub, H.; Luehrmann, R.; Tuschl, T.: Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110 (5), pp. 563 - 574 (2002)

Bartels, C.; Klatt, C.; Luehrmann, R.; Fabrizio, P.: The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome. EMBO Reports 3 (9), pp. 875 - 880 (2002)

Dellaire, G.; Makarov, E. M.; Cowger, J. J. M.; Longman, D.; Sutherland, H. G. E.; Luehrmann, R.; Torchia, J.; Bickmore, W. A.: Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes. Molecular and Cellular Biology 22 (14), pp. 5141 - 5156 (2002)

Schneider, C.; Will, C. L.; Makarova, O.; Makarov, E. M.; Luehrmann, R.: Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions. Molecular and Cellular Biology 22 (10), pp. 3219 - 3229 (2002)

Makarova, O.; Makarov, E. M.; Liu, S.; Vornlocher, H. P.; Luehrmann, R.: Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6 center dot U5 tri-snRNP formation and pre-mRNA splicing. EMBO Journal 21 (5), pp. 1148 - 1157 (2002)

Huber, J.; Dickmanns, A.; Luehrmann, R.: The importin-beta binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro. Journal of Cell Biology 156 (3), pp. 467 - 479 (2002)

Urlaub, H.; Hartmuth, K.; Luehrmann, R.: A two-tracked approach to analyze RNA-protein crosslinking sites in native, nonlabeled small nuclear ribonucleoprotein particles. Methods 26 (2), pp. 170 - 181 (2002)

Mougin, A.; Gottschalk, A.; Fabrizio, P.; Luehrmann, R.; Branlant, C.: Direct probing of RNA structure and RNA-protein interactions in purifies HeLa cells and yeast spliceosomal U4/U6.U5 tri-snRNP particles. Journal of Biological Chemistry 317 (5), pp. 631 - 649 (2002)

Achsel, T.; Stark, H.; Luehrmann, R.: The Sm domain is an ancient RNA binding motif with oligo[U] specificity. Proceedings of the National Academy of Sciences USA 98, pp. 3685 - 3689 (2001)

Brahms, H.; Meheus, L.; De Brabandere, V.; Fischer, U.; Luehrmann, R.: Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein. RNA 7, pp. 1531 - 1542 (2001)

Gottschalk, A.; Kastner, B.; Luehrmann, R.; Fabrizio, P.: The yeast U5 snRNP co-isolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p. RNA 7, pp. 1554 - 1566 (2001)

Gottschalk, A.; Neubauer, G.; Luehrmann, R.; Fabrizio, P.: A novel yeast U2 snRNP protein, Snu17p, is required for the first catalytic step of splicing and for progression of spliceosome assembly. Molecular and Cellular Biology 21, pp. 3037 - 3046 (2001)

Kues, T.; Dickmanns, A.; Luehrmann, R.; Peters, R.; Kubitscheck, U.: High intranuclear mobility and dynamic clustering of the splicing factor U1 snRNP observed by single particle tracking. Proceedings of the National Academy of Sciences USA 98, pp. 12021 - 12026 (2001)

Makarova, O.; Makarov, E. M.; Luehrmann, R.: The 65-kD and 110-kD SR-related proteins of the human [U4/U6.U5] tri-snRNP are essential for association of the tri-snRNP with pre-spliceosomes. EMBO Journal 10, pp. 2553 - 2563 (2001)

Pillai, R. S.; Will, C. L.; Luehrmann, R.; Schuemperli, D.; Mueller, B.: Purified U7 snRNPs lack the Sm proteins D 1 and D 2 but contain Lsm 10, a new 14-kDa Sm D 1-like protein. EMBO Journal 20, pp. 5470 - 5479 (2001)

Stark, H.; Dube, P.; Luehrmann, R.; Kastner, B.: Arrangement of RNA and Proteins in the spliceosomal U1 snRNP. Nature 409, pp. 539 - 542 (2001)

Stark, H.; Dube, P.; Luehrmann, R.; Kastner, B.: The 3-D arrangement for RNA and Proteins in the spliceosomal U1 snRNP. Nature 409, pp. 539 - 542 (2001)

Urlaub, H.; Raker, V. A.; Kostka, S.; Luehrmann, R.: Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure. EMBO Journal 20, pp. 187 - 196 (2001)

Vidovic, I.; Nottrott, S.; Hartmuth, K.; Luehrmann, R.; Ficner, R.: Crystal structure of the spliceosomal 15.5 kD protein bound to a U4 snRNA fragment. Molecular Cell 6, pp. 1331 - 1342 (2001)

Will, C. L.; Luehrmann, R.: Spliceosomal U snRNP biogenesis, structure and function. Current Opinion in Cell Biology 13, pp. 290 - 301 (2001)