Publications of M. Holt

Kiessling, V.; Ahmed, S.; Domanska, M. K.; Holt, M.; Jahn, R.; Tamm, L. K.: Rapid fusion of synaptic vesicles with reconstituted target SNARE membranes. Biophysical Journal 104 (9), pp. 1950 - 1958 (2013)

Ahmed, S.; Holt, M.; Riedel, D.; Jahn, R.: Small-scale isolation of synaptic vesicles from mammalian brain. Nature Protocols 8 (5), pp. 998 - 1009 (2013)

Ghosh, S. K.; Castorph, S.; Konovalov, O.; Salditt, T.; Jahn, R.; Holt, M.: Measuring Ca2+-induced structural changes in lipid monolayers: implications for synaptic vesicle exocytosis. Biophysical Journal 102 (6), pp. 1394 - 1402 (2012)

Park, Y.; Hernandez, J. M.; van den Bogaart, G.; Ahmed, S.; Holt, M.; Riedel, D.; Jahn, R.: Controlling synaptotagmin activity by electrostatic screening. Nature Structural and Molecular Biology 19 (10), pp. 991 - 997 (2012)

Castorph, S.; Henriques, S. S.; Holt, M.; Riedel, D.; Jahn, R.; Salditt, T.: Synaptic vesicles studied by dynamic light scattering. The European Physical Journal E 34 (6), 63 (2011)

van den Bogaart, G.; Thutupalli, S.; Risselada, H. J.; Meyenberg, K.; Holt, M.; Riedel, D.; Diederichsen, U.; Herminghaus, S.; Grubmüller, H.; Jahn, R.: Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation. Nature Structural and Molecular Biology 18 (7), pp. 805 - 812 (2011)

Grömer, T. W.; Thiel, C.; Holt, M.; Riedel, D.; Hua, Y.; Hueve, J.; Wilhelm, B. G.; Klingauf, J.: Amyloid precursor protein is trafficked and secreted via synaptic vesicles. PLoS One 6 (4), e18754 (2011)

Castorph, S.; Riedel, D.; Arleth, L.; Sztucki, M.; Jahn, R.; Holt, M.; Salditt, T.: Structure parameters of synaptic vesicles quantified by small-angle x-ray scattering. Biophysical Journal 98 (7), pp. 1200 - 1208 (2010)

van den Bogaart, G.; Holt, M.; Bunt, G.; Riedel, D.; Wouters, F. S.; Jahn, R.: One SNARE complex is sufficient for membrane fusion. Nature Structural and Molecular Biology 17 (3), pp. 358 - 364 (2010)

Ghosh, S. K.; Castorph, S.; Konovalov, O.; Jahn, R.; Holt, M.; Salditt, T.: In vitro study of interaction of synaptic vesicles with lipid membranes. New Journal of Physics 12, 105004 (2010)

Hosoi, N.; Holt, M.; Sakaba, T.: Calcium dependence of exo- and endocytotic coupling at a glutamatergic synapse. Neuron 63 (2), pp. 216 - 229 (2009)

Rummel, A.; Haefner, K.; Mahrhold, S.; Darashchonak, N.; Holt, M.; Jahn, R.; Beermann, S.; Karnath, T.; Bigalke, H.; Binz, T.: Botulinum neurotoxins C, E and F bind gangliosides via a conserved binding site prior to stimulation-dependent uptake with botulinum neurotoxin F utilising the three isoforms of SV2 as second receptor. Journal of Neurochemistry 110 (6), pp. 1942 - 1954 (2009)

Holt, M.; Riedel, D.; Stein, A.; Schuette, C.; Jahn, R.: Synaptic vesicles are constitutively active fusion machines that function independently of Ca²⁺. Current Biology 18 (10), pp. 715 - 722 (2008)

Takamori, S.; Holt, M.; Stenius, K.; Lemke, E.; Groenborg, M.; Riedel, D.; Urlaub, H.; Schenck, S.; Bruegger, B.; Ringler, P. et al.; Mueller, S.; Rammner, B.; Graeter, F.; Hub, J. S.; de Groot, B. L.; Mieskes, G.; Moriyama, Y.; Klingauf, J.; Grubmueller, H.; Heuser, J.; Wieland, F.; Jahn, R.: Molecular anatomy of a trafficking organelle. Cell 127 (4), pp. 831 - 846 (2006)

Holt, M.; Varoqueaux, F.; Wiederhold, K.; Takamori, S.; Urlaub, H.; Fasshauer, D.; Jahn, R.: Identification of SNAP-47, a novel Qbc-SNARE with ubiquitous expression. Journal of Biological Chemistry 281, pp. 17076 - 17083 (2006)

Holt, M.; Jahn, R.: Synaptic vesicles in the fast lane. Science 303 (5666), pp. 1986 - 1987 (2004)

Kiessling, V.; Ahmed, S.; Domanska, M. K.; Holt, M.; Jahn, R.; Tamm, L. K.: Fast snare mediated synaptic vesicle fusion in supported membranes. 57th Annual Meeting of the Biophysical-Society, Philadelphia/PA, February 02, 2013 - February 06, 2013. Biophysical Journal 104 (Supplement 1), 2 Ed., p. 68A - 68A (2013)

Castorph, S.; Arleth, L.; Sztucki, M.; Vainio, U.; Ghosh, S. K.; Holt, M.; Jahn, R.; Salditt, T.: Synaptic vesicles studied by SAXS: Derivation and validation of a model form factor. 14. International Conference on Small-Angle Scattering, Oxford, UK, September 13, 2009 - September 18, 2009. Journal of Physics: Conference Series 247 (1), 012015, pp. 012015-1 - 012015-17 (2010)

Holt, M.; Riedel, D.; Schuette, C.; Stein, A.; Jahn, R.: Probing synaptic vesicle fusion with an in vitro system. Journal of General Physiology 130 (1), p. 10a - 10a (2007)