Facility for Light Microscopy

Facility for Light Microscopy

Our mission is to support our users through the entire experimental workflow, including experimental design, sample preparation, data acquisition and analysis.

We provide centralized access to a wide range of high-end microscope systems, cell sorting (FACS), other fluorescence-based technologies, and the IT infrastructure required for data analysis. The Facility operates at two sites, the Fassberg and City Campus. Each site covers core imaging technologies including widefield, laser scanning and spinning disk confocal microscopy, super-resolution (SMLM/STORM, STED, MINFLUX) imaging, as well as flow cytometry. Aligned with local needs, the City Campus site also supports multiphoton microscopy, intravital imaging, and fluorescence lifetime imaging (FLIM). The Fassberg Campus site offers biophysical methods (e.g., mass photometry). An integrated IT infrastructure enables remote access to powerful, GPU-enabled compute resources, offering a wide range of commercial and open source image analysis software.   

We operate by training users, who then become independent in acquiring their data, while the facility staff continues to be available for consultation. We provide standard operating procedures, example workflows, and training videos; we regularly offer basic and advanced courses on imaging and image analysis, and organize company workshops and demonstrations. In specific cases, the facility staff is involved in a collaborative fashion, for example to develop new assays or custom data analysis workflows.

 

Press releases and research news

From conservative to flexible – brain cells adapt differently to dietary changes or disease

When we change our diet or fall ill, our brain has to adapt. Researchers at our institute have discovered that the five most important cell types in the brain differ significantly in their ability to adjust their metabolism to changing influences. (in German) more

Millions in funding for groundbreaking microscopy developments

The research project FAIR CHARM aims to apply innovations from basic scientific research to clinical applications with the aid of high-resolution, real-time imaging. The EU is funding the international and interdisciplinary project with six million Euro.  more

Dopamine nanosensors measure signaling between nerve cells

Göttingen researchers succeeded in measuring the release of the neurotransmitter dopamine from nerve cells with unprecedented accuracy. This enables scientists to study the mechanisms that control dopamine signaling in more detail and to better elucidate the development of related diseases. (in German) more

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