Publikationen von R. Lührmann
Alle Typen
Zeitschriftenartikel (191)
41.
Zeitschriftenartikel
11 (9), e1005539 (2015)
Dynamic contacts of U2, RES, Cwc25, Prp8 and Prp45 proteins with the Pre-mRNA branch-site and 3' splice site during catalytic activation and step 1 catalysis in yeast spliceosomes. PLoS Genetics 42.
Zeitschriftenartikel
21 (11), S. 1993 - 2005 (2015)
Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5‘ splice site. RNA 43.
Zeitschriftenartikel
125 (9), S. 3572 - 3584 (2015)
HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models. Journal of Clinical Investigation 44.
Zeitschriftenartikel
162 (3), S. 690 - 690.e1 (2015)
Snapshot: Spliceosome dynamics III. Cell 45.
Zeitschriftenartikel
162 (2), S. 456 - 456.e1 (2015)
SnapShot: Spliceosome dynamics II. Cell 46.
Zeitschriftenartikel
4, e07320 (2015)
A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing. eLife 47.
Zeitschriftenartikel
161 (6), S. 1474 - 1474.e1 (2015)
SnapShot: Spliceosome dynamics I. Cell 48.
Zeitschriftenartikel
22 (2), S. 138 - 144 (2015)
The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nature Structural and Molecular Biology 49.
Zeitschriftenartikel
29 (1), S. 94 - 107 (2015)
The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome. Genes and Development 50.
Zeitschriftenartikel
289 (50), S. 34683 - 34698 (2014)
Identification of small molecule inhibitors of pre-mRNA splicing. The Journal of Biological Chemistry 51.
Zeitschriftenartikel
111 (44), S. 15622 - 15629 (2014)
Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells. Proceedings of the National Academy of Sciences of the United States of America 52.
Zeitschriftenartikel
21 (10), S. 911 - 918 (2014)
Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex. Nature Structural and Molecular Biology 53.
Zeitschriftenartikel
70 (6), S. 1622 - 1630 (2014)
Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28. Acta Crystallographica D 54.
Zeitschriftenartikel
11 (4), S. 298 - 312 (2014)
Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans. RNA Biology 55.
Zeitschriftenartikel
20 (3), S. 406 - 420 (2014)
Mass spectrometry–based relative quantification of proteins in precatalytic and catalytically active spliceosomes by metabolic labeling (SILAC), chemical labeling (iTRAQ), and label-free spectral count. RNA 56.
Zeitschriftenartikel
21 (12), S. 2162 - 2174 (2013)
Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure 57.
Zeitschriftenartikel
32 (21), S. 2804 - 2818 (2013)
RNA structure analysis of human spliceosomes reveals a compact 3D arrangement of snRNAs at the catalytic core. EMBO Journal 58.
Zeitschriftenartikel
8 (9), e74851 (2013)
The Prp19 complex directly functions in mitotic spindle assembly. PLoS One 59.
Zeitschriftenartikel
341 (6141), S. 80 - 84 (2013)
Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8. Science 60.
Zeitschriftenartikel
19 (7), S. 902 - 915 (2013)
Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system. RNA