Publications of R. Luehrmann

Reidt, U.; Reuter, K.; Achsel, T.; Ingelfinger, D.; Luehrmann, R.; Ficner, R.: Crystal structure of the human U4/U6 small nuclear ribonucleoprotein particle-specific SnuCyp-20, a nuclear cyclophilin. Journal of Biological Chemistry 275, pp. 7439 - 7442 (2000)

Achsel, T.; Brahms, H.; Kastner, B.; Bachi, A.; Wilm, M.; Luehrmann, R.: A doughnut-shaped heteromer of human Sm-like proteins binds to the 3′end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro. EMBO Journal 18, pp. 5789 - 5802 (1999)

Buehler, D.; Raker, V. A.; Luehrmann, R.; Fischer, U.: Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy. Human Molecular Genetics 8, pp. 2351 - 2357 (1999)

Hartmuth, K.; Raker, V. A.; Huber, J.; Branlant, C.; Luehrmann, R.: An unusual chemical reactivity of Sm site adenosines strongly correlates with proper assembly of core U snRNP particles. Journal of Molecular Biology 285, pp. 133 - 147 (1999)

Kambach, C.; Walke, S.; Young, R.; Avis, J. M.; Fortelle, E. D. l.; Raker, V. A.; Luehrmann, R.; Li, J.; Nagai, K.: Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell 96, pp. 375 - 387 (1999)

Nottrott, S.; Hartmuth, K.; Fabrizio, P.; Urlaub, H.; Vidovic, I.; Ficner, R.; Luehrmann, R.: Functional interaction of a novel 15.5kD [U4/U6.U5]tri-snRNP protein with the 5′-stem-loop of U4 snRNA. EMBO Journal 18, pp. 6119 - 6133 (1999)

Paraskeva, E.; Izaurralde, E.; Bischoff, F. R.; Huber, J.; Kutay, U.; Hartmann, E.; Lührmann, R.; Görlich, D.: CRM1-mediated recycling of snurportin 1 to the cytoplasm. Journal of Cell Biology 145 (2), pp. 255 - 264 (1999)

Raker, V. A.; Hartmuth, K.; Kastner, B.; Luehrmann, R.: Spliceosomal U snRNP core assembly: Sm proteins assemble onto an Sm site RNA nonanucleotide in a specific and thermodynamically stable manner. Molecular and Cellular Biology 19, pp. 6554 - 6565 (1999)

Reuter, K.; Nottrott, S.; Fabrizio, P.; Luehrmann, R.; Ficner, R.: Identification, characterization and crystal structure analysis of the human spliceosomal U5 snRNP-specific 15kD protein. Journal of Molecular Biology 294, pp. 515 - 525 (1999)

Segault, V.; Will, C. L.; Polycarpou-Schwarz, M.; Mattaj, I. W.; Branlant, C.; Luehrmann, R.: Conserved loop I of U5 snRNA is dispensible for both catalytic steps of pre-mRNA splicing in HeLa nuclear extracts. Molecular and Cellular Biology 19, pp. 2782 - 2790 (1999)

Will, C. L.; Schneider, C.; Reed, R.; Luehrmann, R.: Identification of both shared and distinct proteins in the major and minor spliceosomes. Science 284, pp. 2003 - 2005 (1999)

Valcarcel, J.; Beggs, J.; Krainer, A.; Lührmann, R. (Eds.): The spliceosome and the regulation of alternative splicing. Cold Spring Harbor Lab. Pr., Cold Spring Harbor, N.Y. (accepted)

Stamm, S.; Smith, C.; Lührmann, R. (Eds.): Alternative pre-mRNA splicing: Theory and protocols. Wiley-VCH, Weinheim (2012), XXXVII, 622 pp.

Kastner, B.; Luehrmann, R.: Purification of U small nuclear ribonucleoprotein particles. Humana Press, Totowa, New York (1999)

Will, C. L.; Luehrmann, R.: Alternative Splicing. Wiley-VCH, New York (1999)

Schmidt, C.; Raabe, M.; Lührmann, R.; Urlaub, H.: Analyzing the protein assembly and dynamics of the human spliceosome with SILAC. In: Stable isotope labeling by amino acids in cell culture (SILAC): Methods and protocols, pp. 227 - 244 (Ed. Warscheid, B.). Springer, New York, N.Y (2014)

Dannenberg, J.; Fabrizio, P.; Will, C. L.; Lührmann, R.: Affinity purification of spliceosomal and small nuclear ribonucleoprotein complexes. In: Handbook of RNA biochemistry, Vol. 2, 2. ed. Ed., pp. 957 - 973 (Eds. Hartmann, R. K.; Bindereif, A.; Schön, A.). Wiley-VCH, Weinheim (2013)

Dybkov, O.; Urlaub, H.; Lührmann, R.: Protein-RNA crosslinking in native ribonucleoprotein particles. In: Handbook of RNA biochemistry, Vol. 2, 2. ed. Ed., pp. 1029 - 1053 (Eds. Hartmann, R. K.; Bindereif, A.; Schön, A.; Westhof, E.). Wiley-VCH, Weinheim (2013)

Fabrizio, P.; Lührmann, R.: The spliceosome in constitutive splicing. In: Alternative pre-mRNA splicing: Theory and protocols, pp. 49 - 64 (Ed. Stamm, S.). Wiley-VCH, Weinheim (2012)

Hartmuth, K.; van Santen, M. A.; Lührmann, R.: Ultracentrifugation in the analysis and purification of spliceosomes assembled In Vitro. In: Alternative pre-mRNA splicing: Theory and protocols, pp. 147 - 153 (Eds. Stamm, S.; Smith, C.; Lührmann, R.). Wiley-VCH, Weinheim (2012)