Publications

2.

Journal Article

Koike, S.; Jahn, R.: Rab GTPases and phosphoinositides fine-tune SNAREs dependent targeting specificity of intracellular vesicle traffic. Nature Communications 15 (1), 2508 (2024)

MPG.PuRe

3.

Journal Article

Cepeda, A. P.; Ninov, M.; Neef, J.; Parfentev, I.; Kusch, K.; Reisinger, E.; Jahn, R.; Moser, T.; Urlaub, H.: Proteomic Analysis Reveals the Composition of Glutamatergic Organelles of Auditory Inner Hair Cells. Molecular & Cellular Proteomics 23 (2), 100704 (2024)

MPG.PuRe

4.

Journal Article

Zhao, Y.; Fang, Q.; Sharma, S.; Jakhanwal, S.; Jahn, R.; Lindau, M.: All SNAP25 molecules in the vesicle–plasma membrane contact zone change conformation during vesicle priming. Proceedings of the National Academy of Sciences of the United States of America 121 (2), e2309161121 (2024)

MPG.PuRe

5.

Journal Article

Alfken, J.; Neuhaus, C.; Major, A.; Taskina, A.; Hoffmann, C.; Ganzella, M.; Petrovic, A.; Zwicker, D.; Fernández-Busnadiego, R.; Jahn, R. et al.; Milovanovic, D.; Salditt, T.: Vesicle condensation induced by synapsin: condensate size, geometry, and vesicle shape deformations. European Physical Journal E 47 (1), 8 (2024)

MPG.PuRe

6.

Journal Article

Jahn, R.; Cafiso, D. C.; Tamm, L. K.: Mechanisms of SNARE proteins in membrane fusion. Nature Reviews Molecular Cell Biology 25, pp. 101 - 118 (2024)

MPG.PuRe

7.

Journal Article

Altas, B.; Tuffy, L. P.; Patrizi, A.; Dimova, K.; Soykan, T.; Brandenburg, C.; Romanowski, A. J.; Whitten, J. R.; Robertson, C. D.; Khim, S. N. et al.; Crutcher, G. W.; Ambrozkiewicz, M.; Yagensky, O.; Krüger-Burg, D. D.; Hammer, M.; Hsiao, H.-H.; Laskowski, P. R.; Dyck, L.; Puche, A. C.; Sassoè-Pognetto, M.; Chua, J. J. E.; Urlaub, H.; Jahn, O.; Brose, N.; Poulopoulos, A.: Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory versus Inhibitory Synapses. Biological Psychiatry, in press (2023)

MPG.PuRe

8.

Journal Article

Binotti, B.; Ninov, M.; Cepeda, A. P.; Ganzella, M.; Matti, U.; Riedel, D.; Urlaub, H.; Sambandan, S.; Jahn, R.: ATG9 resides on a unique population of small vesicles in presynaptic nerve terminals. Autophagy (2023)

MPG.PuRe

9.

Journal Article

Hoffmann, C.; Rentsch, J.; Tsunoyama, T.A.; Chhabra, A.; Aguilar Perez, G.; Chowdhury, R.; Trnka, F.; Korobeinikov, A.A.; Shaib, A.H.; Ganzella, M. et al.; Giannone, G.; Rizzoli, S.O.; Kusumi, A.; Ewers, H.; Milovanovic, D.: Synapsin condensation controls synaptic vesicle sequestering and dynamics. Nature Communications 14 (1), 6730 (2023)

MPG.PuRe

10.

Journal Article

Stief, T.; Gremer, L.; Pribicevic, S.; Espinueva, D. F.; Vormann, K.; Biehl, R.; Jahn, R.; Pérez-Lara, Á.; Lakomek, N.-A.: Intrinsic Disorder of the Neuronal SNARE Protein SNAP25a in its Pre-fusion Conformation. Journal of Molecular Biology 435 (10), 168069 (2023)

MPG.PuRe

11.

Journal Article

Roig Adam, A.; Martínez-López, J.A.; van der Spek, S.J.F.; Achsel, T.; Andres-Alonso, M.; Bagni, C.; Bayés, À.; Biederer, T.; Brose, N.; Chua, J.J.E. et al.; Coba, M.P.; Cornelisse, L.N.; de Juan-Sanz, J.; Goldschmidt, H.L.; Gundelfinger, E.D.; Huganir, R.L.; Imig, C.; Jahn, R.; Jung, H.; Kaeser, P.S.; Kim, E.; Koopmans, F.; Kreutz, M.R.; Lipstein, N.; MacGillavry, H.D.; McPherson, P.S.; O’Connor, V.; Pielot, R.; Ryan, T.A.; Sala, C.; Sheng, M.; Smalla, K.-H.; Thomas, P.D.; Toonen, R.F.; van Weering, J.R.T.; Verpelli, C.; Sullivan, P.F.; Smit, A.B.; Verhage, M.; Hjerling-Leffler, J.: Transcriptional diversity in specific synaptic gene sets discriminates cortical neuronal identity. Biology Direct 18, 22 (2023)

MPG.PuRe

12.

Journal Article

Kosmidis, E.; Shuttle, C. G.; Preobraschenski, J.; Ganzella, M.; Johnson, P. J.; Veshaguri, S.; Holmkvist, J.; Moller, M. P.; Marantos, O.; Marcoline, F. et al.; Grabe, M.; Pedersen, J. L.; Jahn, R.; Stamou, D.: Regulation of the mammalian-brain V-ATPase through ultraslow mode-switching. Nature 611 (7937), pp. 827 - 834 (2022)

MPG.PuRe

pre-print

13.

Journal Article

Weber, M.; von der Emde, H.; Leutenegger, M.; Gunkel, P.; Sambandan, S.; Khan, T. A.; Keller-Findeisen, J.; Cordes, V. C.; Hell, S. W.: MINSTED nanoscopy enters the Ångström localization range. Nature Biotechnology (2022)

MPG.PuRe

14.

Journal Article

Birinci, Y.; Preobraschenski, J.; Ganzella, M.; Jahn, R.; Park, Y.: Author Correction: Isolation of large dense-core vesicles from bovine adrenal medulla for functional studies. Scientific Reports 12, 16738 (2022)

MPG.PuRe

15.

Journal Article

Komorowski, K.; Preobraschenski, J.; Ganzella, M.; Alfken, J.; Neuhaus, C.; Jahn, R.; Salditt, T.: Neurotransmitter uptake of synaptic vesicles studied by X-ray diffraction. European Biophysics Journal 51, pp. 465 - 482 (2022)

MPG.PuRe

16.

Journal Article

Upmanyu, N.; Jin, J.; von der Emde, H.; Ganzella, M.; Bösche, L.; Malviya, V. N.; Zhuleku, E.; Politi, A. Z.; Ninov, M.; Silbern, I. et al.; Leutenegger, M.; Urlaub, H.; Riedel, D.; Preobraschenski, J.; Milosevic, I.; Hell, S. W.; Jahn, R.; Sambandan, S.: Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3. Neuron 110 (9), pp. 1483 - 1497 (2022)

MPG.PuRe

17.

Journal Article

Chang, H.-F.; Schirra, C.; Ninov, M.; Hahn, U.; Ravichandran, K.; Krause, E.; Becherer, U.; Bálint, Š.; Harkiolaki, M.; Urlaub, H. et al.; Valitutti, S.; Baldari, C. T.; Dustin, M. L.; Jahn, R.; Rettig, J.: Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes. Nature Communications 13, 1029 (2022)

MPG.PuRe

18.

Journal Article

Koike, S.; Jahn, R.: SNARE proteins: zip codes in vesicle targeting? Biochemical Journal 479 (3), pp. 273 - 288 (2022)

MPG.PuRe

19.

Journal Article

Mühlhausen, S.; Schmitt, H. D.; Plessmann, U.; Mienkus, P.; Sternisek, P.; Perl, T.; Weig, M.; Urlaub, H.; Bader, O.; Kollmar, M.: Proteogenomics analysis of CUG codon translation in the human pathogen Candida albicans. BMC Biology 19, 258 (2021)

MPG.PuRe

20.

Journal Article

Binotti, B.; Jahn, R.; Pérez-Lara, A.: An overview of the synaptic vesicle lipid composition. Archives of Biochemistry and Biophysics 709, 108966 (2021)

MPG.PuRe

21.

Journal Article

Chen, Y.; Vos, S. M.; Dienemann, C.; Ninov, M.; Urlaub, H.; Cramer, P.: Allosteric transcription stimulation by RNA polymerase II super elongation complex. Molecular Cell 81 (16), pp. 3386 - 3399.e10 (2021)

MPG.PuRe

22.

Journal Article

Juranek, J. K.; Mukherjee, K.; Jahn, R.; Li, J.-Y.: Coordinated bi-directional trafficking of synaptic vesicle and active zone proteins in peripheral nerves. Biochemical and Biophysical Research Communications 559, pp. 92 - 98 (2021)

MPG.PuRe

23.

Journal Article

Witkowska, A.; Heinz, L. P.; Grubmüller, H.; Jahn, R.: Tight docking of membranes before fusion represents a novel, metastable state with unique properties. Nature Communications 12, 3606 (2021)

MPG.PuRe

24.

Journal Article

Kim, C.; Shon, M. J.; Kim, S. H.; Eun, G. S.; Ryu, J.-K.; Hyeon, C.; Jahn, R.; Yoon, T.-Y.: Extreme parsimony in ATP consumption by 20S complexes in the global disassembly of single SNARE complexes. Nature Communications 12, 3206 (2021)

MPG.PuRe

25.

Journal Article

Grothe, T.; Nowak, J.; Jahn, R.; Walla, P. J.: Selected tools to visualize membrane interactions. European Biophysics Journal 50 (2), pp. 211 - 222 (2021)

MPG.PuRe

26.

Journal Article

Wittig, S.; Ganzella, M.; Kostmann, S.; Barth, M.; Riedel, D.; Perez-Lara, A.; Jahn, R.; Schmidt, C.: Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes. Nature Communications 12, 858 (2021)

MPG.PuRe

27.

Journal Article

Wu, X.; Ganzella, M.; Zhou, J.; Zhu, S.; Jahn, R.; Zhang, M.: Vesicle tethering on the surface of phase-separated active zone condensates. Molecular Cell 81 (1), pp. 13 - 24.e7 (2021)

MPG.PuRe

28.

Journal Article

Silbern, I.; Pan, K. T.; Fiosins, M.; Bonn, S.; Rizzoli, S. O.; Fornasiero, E. F.; Urlaub, H.; Jahn, R.: Protein phosphorylation in depolarized synaptosomes: Dissecting primary effects of calcium from synaptic vesicle cycling. Molecular and Cellular Proteomics 20, 100061 (2021)

MPG.PuRe

29.

Journal Article

Birinci, Y.; Preobraschenski, J.; Ganzella, M.; Jahn, R.; Park, Y.: Isolation of large dense-core vesicles from bovine adrenal medulla for functional studies. Scientific Reports 10, 7540 (2020)

MPG.PuRe

30.

Journal Article

Luck, R.; Urban, S.; Karakatsani, A.; Harde, E.; Sambandan, S.; Nicholson, L.; Haverkamp, S.; Mann, R.; Martin-Villalba, A.; Schuman, E. M. et al.; Acker-Palmer, A.; de Almodovar, C. R.: VEGF/VEGFR2 signaling regulates hippocampal axon branching during development. eLife 8, e49818 (2019)

MPG.PuRe

31.

Journal Article

Bocker, H. T.; Heinrich, T.; Liebmann, L.; Hennings, J. C.; Seemann, E.; Gerth, M.; Jakovčevski, I.; Preobraschenski, J.; Kessels, M. M.; Westermann, M. et al.; Isbrandt, D.; Jahn, R.; Qualmann, B.; Hübner, C. A.: The Na⁺/H⁺ exchanger Nhe1 modulates network excitability via GABA release. Cerebral Cortex 29 (10), pp. 4263 - 4276 (2019)

MPG.PuRe

ZIP

32.

Journal Article

Kreutzberger, A. J. B.; Kiessling, V.; Stroupe, C.; Liang, B.; Preobraschenski, J.; Ganzella, M.; Kreutzberger, M. A. B.; Nakamoto, R.; Jahn, R.; Castle, J. D. et al.; Tamm, L. K.: In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties. Nature Communications 10, 3904 (2019)

MPG.PuRe

33.

Journal Article

Yagensky, O.; Kohansal-Nodehi, M.; Gunaseelan, S.; Rabe, T.; Zafar, S.; Zerr, I.; Haertig, W.; Urlaub, H.; Chua, J.: Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity. eLife 8, e47498 (2019)

MPG.PuRe

34.

Journal Article

Koopmans, F.; van Nierop, P.; Andres-Alonso, M.; Byrnes, A.; Cijsouw, T.; Coba, M. P.; Cornelisse, L. N.; Farrell, R. J.; Goldschmidt, H. L.; Howrigan, D. P. et al.; Hussain, N. K.; Imig, C.; de Jong, A. P. H.; Jung, H.; Kohansalnodehi, M.; Kramarz, B.; Lipstein, N.; Lovering, R. C.; MacGillavry, H.; Mariano, V.; Mi, H.; Ninov, M.; Osumi-Sutherland, D.; Pielot, R.; Smalla, K. H.; Tang, H.; Tashman, K.; Toonen, R. F. G.; Verpelli, C.; Reig-Viader, R.; Watanabe, K.; van Weering, J.; Achsel, T.; Ashrafi, G.; Asi, N.; Brown, T. C.; De Camilli, P.; Feuermann, M.; Foulger, R. E.; Gaudet, P.; Joglekar, A.; Kanellopoulos, A.; Malenka, R.; Nicoll, R. A.; Pulido, C.; de Juan-Sanz, J.; Sheng, M.; Südhof, T. C.; Tilgner, H. U.; Bagni, C.; Bayés, A.; Biederer, T.; Brose, N.; Chua, J. J. E.; Dieterich, D. C.; Gundelfinger, E. D.; Hoogenraad, C.; Huganir, R. L.; Jahn, R.; Kaeser, P. S.; Kim, E.; Kreutz, M. R.; McPherson, P. S.; Neale, B. M.; O’Connor, V.; Posthuma, D.; Ryan, T. A.; Sala, C.; Feng, G.; Hyman, S. E.; Thomas, P. D.; Smit, A. B.; Verhage, M.: SynGO: An evidence-based, expert-curated knowledge base for the synapse. Neuron 103 (2), pp. 217 - 234 (2019)

MPG.PuRe

35.

Journal Article

Saito, M.; Koike, S.; Holm, K.; Bregolin, F. L.; Hofsäss, H.: External RBS/PIXE analysis for evaluating quantum dots internalization into HeLa cells. Nuclear Instruments and Methods in Physics Research B 450, pp. 173 - 178 (2019)

MPG.PuRe

36.

Journal Article

Raja, M. K.; Preobraschenski, J.; Del Olmo-Cabrera, S.; Martinez-Turrillas, R.; Jahn, R.; Perez-Otano, I.; Wesseling, J. F.: Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts. eLife 8, e40744 (2019)

MPG.PuRe

37.

Journal Article

Lakomek, N. A.; Yavuz, H.; Jahn, R.; Perez-Lara, A.: Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion. Proceedings of the National Academy of Sciences of the United States of America 116 (18), pp. 8699 - 8708 (2019)

MPG.PuRe

38.

Journal Article

Koike, S.; Jahn, R.: SNAREs define targeting specificity of trafficking vesicles by combinatorial interaction with tethering factors. Nature Communicationsvolume 10, 1608 (2019)

MPG.PuRe

39.

Journal Article

Hubrich, R.; Park, Y.; Mey, I.; Jahn, R.; Steinem, C.: SNARE-mediated fusion of single chromaffin granules with pore-spanning membranes. Biophysical Journal 116 (2), pp. 308 - 318 (2019)

MPG.PuRe

40.

Journal Article

Brose, N.; Brunger, A.; Cafiso, D.; Chapman, E. R.; Diao, J.; Hughson, F. M.; Jackson, M. B.; Jahn, R.; Lindau, M.; Ma, C. et al.; Rizo, J.; Shin, Y. K.; Söllner, T. H.; Tamm, L.; Yoon, T. Y.; Zhang, Y.: Synaptic vesicle fusion: Today and beyond. Nature Structural and Molecular Biology 26 (8), pp. 663 - 668 (2019)

MPG.PuRe

41.

Journal Article

Hubrich, B.; Kumar, P.; Neitz, H.; Grunwald, M.; Grothe, T.; Walla, P. J.; Jahn, R.; Diederichsen, U.: PNA hybrid sequences as recognition units in SNARE-protein-mimicking peptides. Angewandte Chemie International Edition 57 (45), pp. 14932 - 14936 (2018)

MPG.PuRe

42.

Journal Article

Oroz, J.; Chang, B. J.; Wysoczanski, P.; Lee, C. T.; Perez-Lara, A.; Chakraborty, P.; Hofele, R. V.; Baker, J. D.; Blair, L. J.; Biernat, J. et al.; Urlaub, H.; Mandelkow, E.; Dickey, C. A.; Zweckstetter, M.: Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. Nature Communications 9, 4532 (2018)

MPG.PuRe

43.

Journal Article

Bassereau, P.; Jin, R.; Baumgart, T.; Deserno, M.; Dimova, R.; Frolov, V. A.; Bashkirov, P. V.; Grubmüller, H.; Jahn, R.; Risselada, H. J. et al.; Johannes, L.; Kozlov, M. M.; Lipowsky, R.; Pucadyil, T. J.; Zeno, W. F.; Stachowiak, J. C.; Stamou, D.; Breuer, A.; Lauritsen, L.; Simon, C.; Sykes, C.; Voth, G. A.; Weikl, T. R.: The 2018 biomembrane curvature and remodeling roadmap. Journal of Physics D: Applied Physics 51 (34), 343001 (2018)

MPG.PuRe

44.

Journal Article

Witkowska, A.; Jablonski, L.; Jahn, R.: A convenient protocol for generating giant unilamellar vesicles containing SNARE proteins using electroformation. Scientific Reports 8, 9422 (2018)

MPG.PuRe

45.

Journal Article

Yavuz, H.; Kattan, I.; Hernandez, J. M.; Hofnagel, O.; Witkowska, A.; Raunser, S.; Walla, P. J.; Jahn, R.: Arrest of trans-SNARE zippering uncovers loosely and tightly docked intermediates in membrane fusion. Journal of Biological Chemistry 293 (22), pp. 8645 - 8655 (2018)

MPG.PuRe

46.

Journal Article

Komorowski, K.; Salditt, A.; Xu, Y.; Yavuz, H.; Brennich, M.; Jahn, R.; Salditt, T.: Vesicle adhesion and fusion studied by small-angle x-ray scattering. Biophysical Journal 114 (8), pp. 1908 - 1920 (2018)

MPG.PuRe

47.

Journal Article

Farsi, Z.; Gowrisankaran, S.; Krunic, M.; Rammner, B.; Woehler, A.; Lafer, E. M.; Mim, C.; Jahn, R.; Milosevic, I.: Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity. eLife 7, e32569 (2018)

MPG.PuRe

48.

Journal Article

Preobraschenski, J.; Chere, C.; Ganzella, M.; Zander, J. F.; Richter, K.; Schenck, S.; Jahn, R.; Ahnert-Hilger, G.: Dual and direction-selective mechanisms of phosphate transport by the vesicular glutamate transporter. Cell Reports 23 (2), pp. 535 - 545 (2018)

MPG.PuRe

49.

Journal Article

Xu, Y.; Kuhlmann, J.; Brennich, M.; Komorowski, K.; Jahn, R.; Steinem, C.; Salditt, T.: Reconstitution of SNARE proteins into solid-supported lipid bilayer stacks and X-ray structure analysis. Biochimica et Biophysica Acta (BBA) - Biomembranes 1860 (2), pp. 566 - 578 (2018)

MPG.PuRe

50.

Journal Article

Bharat, V.; Siebrecht, M.; Burk, K.; Ahmed, S.; Reissner, C.; Kohansal-Nodehi, M.; Steubler, V.; Zweckstetter, M.; Ting, J. T.; Dean, C.: Capture of dense core vesicles at synapses by JNK-dependent phosphorylation of Synaptotagmin-4. Cell Reports 21 (8), pp. 2118 - 2133 (2017)

MPG.PuRe