Publications

102.

Journal Article

Biesemann, C.; Groenborg, M.; Luquet, E.; Wichert, S. P.; Bernard, V.; Bungers, S. R.; Cooper, B.; Varoqueaux, F.; Li, L.; Byrne, J. A. et al.; Urlaub, H.; Jahn, O.; Brose, N.; Herzog, E.: Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. EMBO Journal 33 (2), pp. 157 - 170 (2014)

MPG.PuRe

103.

Journal Article

Behrens, C.; Binotti, B.; Schmidt, C.; Robinson, C. V.; Chua, J. J. E.; Kühnel, K.: Crystal structure of the human short coiled coil protein and insights into SCOC-FEZ1 complex formation. PLoS One 8 (10), e76355 (2013)

MPG.PuRe

104.

Journal Article

Juranek, J. K.; Mukherjee , K.; Siddiqui, T. J.; Kaplan, B. J.; Li , J. Y.; Ahnert-Hilger, G.; Jahn, R.; Calka, J.: Active zone protein expression changes at the key stages of cerebellar cortex neurogenesis in the rat. Acta Histochemica 116 (6), pp. 616 - 625 (2013)

MPG.PuRe

105.

Journal Article

Kiessling, V.; Ahmed, S.; Domanska, M. K.; Holt, M.; Jahn, R.; Tamm, L. K.: Rapid fusion of synaptic vesicles with reconstituted target SNARE membranes. Biophysical Journal 104 (9), pp. 1950 - 1958 (2013)

MPG.PuRe

106.

Journal Article

Busse, R. A.; Scacioc, A.; Hernandez, J. M.; Krick, R.; Stephan , M.; Janshoff, A.; Thumm, M.; Kühnel, K.: Qualitative and quantitative characterization of protein-phosphoinositide interactions with liposome-based methods. Autophagy 9 (5), pp. 1 - 8 (2013)

MPG.PuRe

107.

Journal Article

Ahmed, S.; Holt, M.; Riedel, D.; Jahn, R.: Small-scale isolation of synaptic vesicles from mammalian brain. Nature Protocols 8 (5), pp. 998 - 1009 (2013)

MPG.PuRe

108.

Journal Article

Boyken, J.; Grønborg, M.; Riedel, D.; Urlaub, H.; Jahn, R.; Chua, J. J.: Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Neuron 78 (2), pp. 285 - 297 (2013)

MPG.PuRe

109.

Journal Article

Khuong, T. M.; Habets, R. L. P.; Kuenen, S.; Witkowska, A.; Kasprowicz, J.; Swerts, J.; Jahn, R.; van den Bogaart, G.; Verstreken, P.: Synaptic PI(3,4,5)P-3 is required for Syntaxin1A clustering and neurotransmitter release. Neuron 77 (6), pp. 1097 - 1108 (2013)

MPG.PuRe

110.

Journal Article

Martineau, M.; Shi, T.; Puyal, J.; Knolhoff, A. M.; Dulong, J.; Gasnier, B.; Klingauf, J.; Sweedler, J. V.; Jahn, R.; Mothet, J. P.: Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission. Journal of Neuroscience 33 (8), pp. 3413 - 3423 (2013)

MPG.PuRe

111.

Journal Article

Chua, J. J.; Jahn, R.; Klopfenstein, D. R.: Managing intracellular transport. Worm 2 (1), 21564 (2013)

MPG.PuRe

112.

Journal Article

Honigmann, A.; van den Bogaart, G.; Iraheta, E.; Risselada, H. J.; Milovanovic, D.; Müller, V.; Müller, S.; Diederichsen, U.; Fasshauer, D.; Grubmüller, H. et al.; Hell, S. W.; Eggeling, C.; Kühnel, K.; Jahn, R.: Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment. Nature Structural and Molecular Biology 20, pp. 679 - 686 (2013)

MPG.PuRe

113.

Journal Article

Thumm, M.; Busse, R. A.; Scacioc, A.; Stephan, M.; Janshoff, A.; Kühnel, K.; Krick, R.: It takes two to tango: PROPPINs use two phosphoinositide-binding sites. Autophagy 9 (1), pp. 106 - 107 (2013)

MPG.PuRe

114.

Journal Article

Jahn, R.; Fasshauer, D.: Molecular machines governing exocytosis of synaptic vesicles. Nature 490 (7419), pp. 201 - 207 (2012)

MPG.PuRe

115.

Journal Article

Krick, R.; Busse, R. A.; Scacioc, A.; Stephan, M.; Janshoff, A.; Thumm, M.; Kühnel, K.: Structural and functional characterization of the two phosphoinositide binding sites of PROPPINs. Proceedings of the National Academy of Sciences of the United States of America 109 (30), pp. E2042 - E2049 (2012)

MPG.PuRe

116.

Journal Article

Vennekate, W.; Schröder, S.; Lin, C. C.; van den Bogaart, G.; Grunwald, M.; Jahn, R.; Walla, P. J.: Cis- and trans-membrane interactions of synaptotagmin-1. Proceedings of the National Academy of Siences of the United States of America 109 (27), pp. 11037 - 11042 (2012)

MPG.PuRe

117.

Journal Article

Hernandez, J. M.; Stein, A.; Behrmann, E.; Riedel, D.; Cypionka, A.; Farsi, Z.; Walla, P. J.; Raunser, S.; Jahn, R.: Membrane fusion intermediates via directional and full assembly of the SNARE complex. Science 336 (6088), pp. 1581 - 1584 (2012)

MPG.PuRe

118.

Journal Article

van den Bogaart, G.; Meyenberg, K.; Diederichsen, U.; Jahn, R.: Phosphatidylinositol 4,5-bisphosphate increases the Ca2+ affinity of synaptotagmin-1 40-fold. Journal of Biological Chemistry 287 (20), pp. 16447 - 16453 (2012)

MPG.PuRe

119.

Journal Article

Chua, J. J. E.; Butkevich, E.; Worseck, J. M.; Kittelmann, M.; Gronborg, M.; Behrmann, E.; Stelzl, U.; Pavlos, N. J.; Lalowski, M. M.; Eimer, S. et al.; Wanker, E. E.; Klopfenstein, D. R.; Jahn, R.: Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter. Proceedings of the National Academy of Sciences of the United States of America 109 (15), pp. 5862 - 5867 (2012)

MPG.PuRe

120.

Journal Article

Ghosh, S. K.; Castorph, S.; Konovalov, O.; Salditt, T.; Jahn, R.; Holt, M.: Measuring Ca2+-induced structural changes in lipid monolayers: implications for synaptic vesicle exocytosis. Biophysical Journal 102 (6), pp. 1394 - 1402 (2012)

MPG.PuRe

121.

Journal Article

Park, Y.; Hernandez, J. M.; van den Bogaart, G.; Ahmed, S.; Holt, M.; Riedel, D.; Jahn, R.: Controlling synaptotagmin activity by electrostatic screening. Nature Structural and Molecular Biology 19 (10), pp. 991 - 997 (2012)

MPG.PuRe

122.

Journal Article

Lygina, A. S.; Meyenberg, K.; Jahn, R.; Diederichsen, U.: Transmembrane domain peptide/peptide nucleic acid hybrid as a model of a SNARE protein in vesicle fusion. Angewandte Chemie-International Edition 50 (37), pp. 8597 - 8601 (2011)

MPG.PuRe

123.

Journal Article

Sinha, R.; Ahmed, S.; Jahn, R.; Klingauf, J.: Two synaptobrevin molecules are sufficient for vesicle fusion in central nervous system synapses. Proceedings of the National Academy of Sciences of the United States of America 108 (34), pp. 14318 - 14323 (2011)

MPG.PuRe

124.

Journal Article

van den Bogaart, G.; Jahn, R.: Counting the SNAREs needed for membrane fusion. Journal of Molecular Cell Biology 3 (4), pp. 204 - 205 (2011)

MPG.PuRe

125.

Journal Article

Meiringer, C. T. A.; Rethmeier, R.; Auffarth, K.; Wilson, J.; Perz, A.; Barlowe, C.; Schmitt, H. D.; Ungermann, C.: The Dsl1 protein tethering complex is a resident endoplasmic reticulum complex, which interacts with five soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptors (SNAREs) implications for fusion and fusion regulation. Journal of Biological Chemistry 286 (28), pp. 25039 - 25046 (2011)

MPG.PuRe

126.

Journal Article

van den Bogaart, G.; Jahn, R.: Inside insight to membrane fusion. Proceedings of the National Academy of Sciences of the United States of America 108 (29), pp. 11729 - 11730 (2011)

MPG.PuRe

127.

Journal Article

Castorph, S.; Henriques, S. S.; Holt, M.; Riedel, D.; Jahn, R.; Salditt, T.: Synaptic vesicles studied by dynamic light scattering. The European Physical Journal E 34 (6), 63 (2011)

MPG.PuRe

128.

Journal Article

van den Bogaart, G.; Thutupalli, S.; Risselada, H. J.; Meyenberg, K.; Holt, M.; Riedel, D.; Diederichsen, U.; Herminghaus, S.; Grubmüller, H.; Jahn, R.: Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation. Nature Structural and Molecular Biology 18 (7), pp. 805 - 812 (2011)

MPG.PuRe

129.

Journal Article

Pulido, I. R.; Jahn, R.; Gerke, V.: VAMP3 is associated with endothelial Weibel-Palade bodies and participates in their Ca2+-dependent exocytosis. Biochimica et Biophysica Acta-Molecular Cell Research 1813 (5), pp. 1038 - 1044 (2011)

MPG.PuRe

130.

Journal Article

Grömer, T. W.; Thiel, C.; Holt, M.; Riedel, D.; Hua, Y.; Hueve, J.; Wilhelm, B. G.; Klingauf, J.: Amyloid precursor protein is trafficked and secreted via synaptic vesicles. PLoS One 6 (4), e18754 (2011)

MPG.PuRe

131.

Journal Article

Zilly, F. E.; Halemani, N.; Walrafen, D.; Spitta, L.; Schreiber, A.; Jahn, R.; Lang, T.: Ca2+ induces clustering of membrane proteins in the plasma membrane via electrostatic interactions. EMBO Journal 30 (7), pp. 1209 - 1220 (2011)

MPG.PuRe

132.

Journal Article

Ahnert-Hilger, G.; Jahn, R.: CLC-3 spices up GABAergic synaptic vesicles. Nature Neuroscience 14 (4), pp. 405 - 407 (2011)

MPG.PuRe

133.

Journal Article

Kühnel, K.; Diezmann, D.: Crystal structure of the autochaperone region from the Shigella flexneri autotransporter IcsA. Journal of Bacteriology 193 (8), pp. 2042 - 2045 (2011)

MPG.PuRe

134.

Journal Article

Pavlos, N. J.; Cheng, T. S.; Quin, A.; Ng, P. Y.; Feng, H. T.; Ang, E. S. M.; Carello, A.; Sung, C. H.; Jahn, R.; Zheng, M. H. et al.; Xu, J.: Tctex-1, a novel interaction partner of Rab3D, is required for osteoclastic bone resorption. Molecular and Cellular Biology 31 (7), pp. 1551 - 1564 (2011)

MPG.PuRe

135.

Journal Article

Meyenberg, K.; Lygina, A. S.; van den Bogaart, G.; Jahn, R.; Diederichsen, U.: SNARE derived peptide mimic inducing membrane fusion. Chemical Communications 47 (33), pp. 9405 - 9407 (2011)

MPG.PuRe

136.

Journal Article

Pavlos, N. J.; Jahn, R.: Distinct yet overlapping roles of Rab GTPases on synaptic vesicles. Small GTPases 2 (2), pp. 77 - 81 (2011)

MPG.PuRe

137.

Journal Article

van den Bogaart, G.; Meyenberg, K.; Risselada, H. J.; Amin, H.; Willig, K.; Hubrich, B. E.; Dier, M.; Hell, S. W.; Grubmüller, H.; Diederichsen, U. et al.; Jahn, R.: Membrane protein sequestering by ionic protein–lipid interactions. Nature 479 (7374), doi:10.1038/nature10545, pp. 552 - 555 (2011)

MPG.PuRe

138.

Journal Article

Jahn, R.: VGLUTs—potential targets for the treatment of seizures? Neuron 68 (1), pp. 6 - 8 (2010)

MPG.PuRe

139.

Journal Article

Pavlos, N. J.; Groenborg, M.; Riedel, D.; Chua, J. J. E.; Boyken, J.; Kloepper, T. H.; Urlaub, H.; Rizzoli, S. O.; Jahn, R.: Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca²⁺-triggered exocytosis. Journal of Neuroscience 30 (40), pp. 13441 - 13453 (2010)

MPG.PuRe

140.

Journal Article

Geumann, C.; Groenborg, M.; Hellwig, M.; Martens, H.; Jahn, R.: A sandwich enzyme-linked immunosorbent assay for the quantification of insoluble membrane and scaffold proteins. Analytical Biochemistry 402 (2), pp. 161 - 169 (2010)

MPG.PuRe

141.

Journal Article

Geumann, U.; Schaefer, C.; Riedel, D.; Jahn, R.; Rizzoli, S. O.: Synaptic membrane proteins form stable microdomains in early endosomes. Microscopy Research and Technique 73 (6), pp. 606 - 617 (2010)

MPG.PuRe

142.

Journal Article

Barysch, S. V.; Jahn, R.; Rizzoli, S. O.: A fluorescence-based in vitro assay for investigating early endosome dynamics. Nature Protocols 5 (6), pp. 1127 - 1137 (2010)

MPG.PuRe

143.

Journal Article

Schmitt, H. D.: Dsl1p/Zw10: common mechanisms behind tethering vesicles and microtubules. Trends in Cell Biology 20 (5), pp. 257 - 268 (2010)

MPG.PuRe

144.

Journal Article

Rickman, C.; Medine, C. N.; Dun, A. R.; Moulton, D. J.; Mandula, O.; Halemani, N.; Rizzoli, S. O.; Chamberlain, L. H.; Duncan, R. R.: t-SNARE protein conformations patterned by the lipid microenvironment. The Journal of Biological Chemistry 285 (18), pp. 13535 - 13541 (2010)

MPG.PuRe

145.

Journal Article

Mukherjee, K.; Sharma, M.; Jahn, R.; Wahl, M. C.; Suedhof, T. C.: Evolution of CASK into a Mg²⁺-sensitive kinase. Science Signaling 3 (119), ra33, pp. 1 - 12 (2010)

MPG.PuRe

146.

Journal Article

Hsu, C.; Morohashi, Y.; Yoshimura, S.; Manrique-Hoyos, N.; Jung, S.; Lauterbach, M.; Bakhti, M.; Grønborg, M.; Moebius, W.; Rhee, J. et al.; Barr, F. A.; Simons, M.: Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C. Journal of Cell Biology 189 (2), pp. 223 - 232 (2010)

MPG.PuRe

147.

Journal Article

Castorph, S.; Riedel, D.; Arleth, L.; Sztucki, M.; Jahn, R.; Holt, M.; Salditt, T.: Structure parameters of synaptic vesicles quantified by small-angle x-ray scattering. Biophysical Journal 98 (7), pp. 1200 - 1208 (2010)

MPG.PuRe

148.

Journal Article

Chua, J.; Kindler, S.; Boyken, J.; Jahn, R.: The architecture of an excitatory synapse. Journal of Cell Sience 123 (6), pp. 819 - 823 (2010)

MPG.PuRe

149.

Journal Article

Halemani, N.; Bethani, I.; Rizzoli, S. O.; Lang, T.: Structure and dynamics of a two-helix SNARE complex in live cells. Traffic 11 (3), pp. 394 - 404 (2010)

MPG.PuRe

150.

Journal Article

van den Bogaart, G.; Holt, M.; Bunt, G.; Riedel, D.; Wouters, F. S.; Jahn, R.: One SNARE complex is sufficient for membrane fusion. Nature Structural and Molecular Biology 17 (3), pp. 358 - 364 (2010)

MPG.PuRe