Zeitschriftenartikel (505)

251.
Zeitschriftenartikel
Strenzke, N.; Chakrabarti, R.; Al-Moyed, H.; Müller, A.; Hoch, G.; Pangrsic, T.; Yamanbaeva, G.; Lenz, C.; Pan, K. T.; Auge, E. et al.; Geiss-Friedlander, R.; Urlaub, H.; Brose, N.; Wichmann, C.; Reisinger, E.: Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants. EMBO Journal 35 (23), S. 2519 - 2535 (2016)
252.
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Zhang, J. N.; Michel, U.; Lenz, C.; Friedel, C. C.; Köster, S.; d'Hedouville, Z.; Tönges, L.; Urlaub, H.; Bähr, M.; Lingor, P. et al.; Koch, J. C.: Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration. Scientific Reports 6, 37050 (2016)
253.
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Manno, B.; Oellerich, T.; Schnyder, T.; Corso, J.; Lösing, M.; Neumann, K.; Urlaub, H.; Batista, F. D.; Engelke, M.; Wienands, J.: The Dok-3/Grb2 adaptor module promotes inducible association of the lipid phosphatase SHIP with the BCR in a coreceptor-independent manner. European Journal of Immunology 46 (11), S. 2520 - 2530 (2016)
254.
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Cretu, C.; Schmitzova, J.; Ponce-Salvatierra, A.; Dybkov, O.; De Laurentiis, E.; Sharma, K.; Will, C. L.; Urlaub, H.; Lührmann, R.; Pena, V.: Molecular architecture of SF3b and structural consequences of its cancer-related mutations. Molecular Cell 64 (2), S. 307 - 319 (2016)
255.
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Martin, S.; Bellora, N.; González-Vallinas, J.; Irimia, M.; Chebli, K.; DeToledo, M.; Raabe, M.; Eyras, E.; Urlaub, H.; Blencowe, B. J. et al.; Tazi, J.: Preferential binding of a stable G3BP ribonucleoprotein complex to intron-retaining transcripts in mouse brain and modulation of their expression in the cerebellum. Journal of Neurochemistry 139 (3), S. 349 - 368 (2016)
256.
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Hsu, M. F.; Pan, K. T.; Chang, F. Y.; Khoo, K. H.; Urlaub, H.; Cheng, C. F.; Chang, G. D.; Haj, F. G.; Meng, T. C.: S-nitrosylation of endogenous protein tyrosine phosphatases in endothelial insulin signaling. Free Radical Biology and Medicine 99, S. 199 - 213 (2016)
257.
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Rauhut, R.; Fabrizio, P.; Dybkov, O.; Hartmuth, K.; Pena, V.; Chari, A.; Kumar, V.; Lee, C. T.; Urlaub, H.; Kastner, B. et al.; Stark, H.; Lührmann, R.: Molecular architecture of the Saccharomyces cerevisiae activated spliceosome. Science 353 (6306), S. 1399 - 1405 (2016)
258.
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Justa-Schuch, D.; Silvia-Garcia, M.; Pilla, E.; Engelke, M.; Kilisch, M.; Lenz, C.; Möller, U.; Nakamura, F.; Urlaub, H.; Geiss-Friedlander, R.: DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk. eLife 5, e16370 (2016)
259.
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Veit, J.; Sachsenberg, T.; Chernev, A.; Aichler, F.; Urlaub, H.; Kohlbacher, O.: LFQProfiler and RNPxl: Open-source tools for label-free quantification and protein-RNA cross-linking integrated into Proteome Discoverer. Journal of Proteome Research 15 (9), S. 3441 - 3448 (2016)
260.
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Agafonov, D. E.; van Santen, M.; Kastner, B.; Dube, P.; Will, C. L.; Urlaub, H.; Lührmann, R.: ATPγS stalls splicing after B complex formation but prior to spliceosome activation. RNA 22 (9), S. 1329 - 1337 (2016)
261.
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Narayanan, P.; Sondermann, J.; Rouwette, T.; Karaca, S.; Urlaub, H.; Mitkovski, M.; Gomez-Varela, D.; Schmidt, M.: Native Piezo2 interactomics identifies pericentrin as a novel regulator of Piezo2 in somatosensory neurons. Journal of Proteome Research 15 (8), S. 2676 - 2687 (2016)
262.
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Helmke, C.; Raab, M.; Rödel, F.; Matthess, Y.; Oellerich, T.; Mandal, R.; Sanhaji, M.; Urlaub, H.; Rödel, C.; Becker, S. et al.; Strebhardt, K.: Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8. Cell Research 26 (8), S. 914 - 934 (2016)
263.
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Lazzaretti, D.; Veith, K.; Kramer, K.; Basquin, C.; Urlaub, H.; Iron, U.; Bono, F.: The bicoid mRNA localization factor Exuperantia is an RNA-binding pseudonuclease. Nature Structural and Molecular Biology 23 (8), S. 705 - 713 (2016)
264.
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Gleditzsch, D.; Müller-Esparza, H.; Pausch, P.; Sharma, K.; Dwarakanath, S.; Urlaub, H.; Bange, G.; Randau, L.: Modulating the Cascade architecture of a minimal Type I-F CRISPR-Cas system. Nucleic Acids Research 44 (12), S. 5872 - 5882 (2016)
265.
Zeitschriftenartikel
Seehusen, F.; Kiel, K.; Jottini, S.; Wohlsein, P.; Habierski, H.; Seibel, K.; Vogel, T.; Urlaub, H.; Kollmar, M.; Baumgärtner, W. et al.; Teichmann, U.: Axonopathy in the central nervous system is the hallmark of mice with a novel intragenic null mutation of dystonin. Genetics 204 (1), S. 191 - 203 (2016)
266.
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Boesler, C.; Rigo, N.; Anokhina, M. M.; Tauchert, M. J.; Agafonov, D. E.; Kastner, B.; Urlaub, H.; Ficner, R.; Will, C. L.; Lührmann, R.: A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity. Nature Communications 7, 11997 (2016)
267.
Zeitschriftenartikel
Mühlhausen, S.; Findeisen, P.; Plessmann, U.; Urlaub, H.; Kollmar, M.: A novel nuclear genetic code alteration in yeasts and the evolution of codon reassignment in eukaryotes. Genome Research 26 (7), S. 945 - 955 (2016)
268.
Zeitschriftenartikel
Kühn, J.; Wong, L. E.; Pirkuliyeva, S.; Schulz, K.; Schwiegk, C.; Fünfgeld, K.; Keppler, S.; Batista, F. D.; Urlaub, H.; Habeck, M. et al.; Becker, S.; Griesinger, C.; Wienands, J.: The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation. Science Signaling 9 (434), ra66 (2016)
269.
Zeitschriftenartikel
Butkevich, E.; Hartig, W.; Nikolov, M.; Erck, C.; Grosche, J.; Urlaub, H.; Schmidt, C. F.; Klopfenstein, D. R.; Chua, J. J. E.: Phosphorylation of FEZ1 by microtubule affinity regulating kinases regulates its function in presynaptic protein trafficking. Scientific Reports 6, 26965 (2016)
270.
Zeitschriftenartikel
Bareth, B.; Nikolov, M.; Lorenzi, I.; Hildenbeutel, M.; Mick, D. U.; Helbig, C.; Urlaub, H.; Ott, M.; Rehling, P.; Dennerlein, S.: Oms1 associates with cytochrome c oxidase assembly intermediates to stabilize newly synthesized Cox1. Molecular Biology of the Cell 27 (10), S. 1570 - 1580 (2016)
271.
Zeitschriftenartikel
Corso, J.; Pan, K. T.; Walter, R.; Doebele, C.; Mohr, S.; Bohnenberger, H.; Ströbel, P.; Lenz, C.; Slabicki, M.; Hüllein, J. et al.; Comoglio, F.; Rieger, M. A.; Zenz, T.; Wienands, J.; Engelke, M.; Serve, H.; Urlaub, H.; Oellerich, T.: Elucidation of tonic and activated B-cell receptor signaling in Burkitt's lymphoma provides insights into regulation of cell survival. Proceedings of the National Academy of Sciences of the United States of America 113 (20), S. 5688 - 5693 (2016)
272.
Zeitschriftenartikel
Fourmann, J. B.; Dybkov, O.; Agafonov, D. E.; Tauchert, M. J.; Urlaub, H.; Ficner, R.; Fabrizio, P.; Lührmann, R.: The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction. eLife 5, e15564 (2016)
273.
Zeitschriftenartikel
Kohansalnodehi, M.; Chua, J. J.; Urlaub, H.; Jahn, R.; Czernik, D.: Analysis of protein phosphorylation in nerve terminal reveals extensive changes in active zone proteins upon exocytosis. eLife 5, e14530 (2016)
274.
Zeitschriftenartikel
Hiragami-Hamada, K.; Sörös, S.; Nikolov, M.; Wilkins, B.; Kreuz, S.; Chen, C.; De La Rosa-Velazquez, I. A.; Zenn, H. M.; Kost, N.; Pohl, W. et al.; Chernev, A.; Schwarzer, D.; Jenuwein, T.; Lorincz, M.; Zimmermann, B.; Walla, P. J.; Neumann, H.; Baubec, T.; Urlaub, H.; Fischle, W.: Dynamic and flexible H3K9me3 bridging via HP1beta dimerization establishes a plastic state of condensed chromatin. Nature Communications 7, 11310 (2016)
275.
Zeitschriftenartikel
Shao, Y. M.; Richter , H.; Sun, S.; Sharma, K.; Urlaub, H.; Randau, L.: A non-stem-loop CRISPR RNA is processed by dual binding Cas6. Structure 24 (4), S. 547 - 554 (2016)
276.
Zeitschriftenartikel
Khan, N.; Lenz, C.; Binder, L.; Pantakani, D. V. K.; Asif, A. R.: Active and repressive chromatin-associated proteome after MPA treatment and the role of midkine in epithelial monolayer permeability. International Journal of Molecular Sciences 17 (4), 597 (2016)
277.
Zeitschriftenartikel
Agafonov, D. E.; Kastner, B.; Dybkov, O.; Hofele, R. V.; Liu, W.; Urlaub, H.; Lührmann, R.; Stark, H.: Molecular architecture of the human U4/U6.U5 tri-snRNP. Science 351 (6280), S. 1416 - 1420 (2016)
278.
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Heininger, A. U.; Hackert, P.; Andreou, A. Z.; Boon, K. L.; Memet, I.; Prior, M.; Clancy, A.; Schmidt, B.; Urlaub, H.; Schleiff, E. et al.; Sloan, K. E.; Deckers, M.; Lührmann, R.; Enderlein, J.; Klostermeier, D.; Rehling, P.; Bohnsack, M. T.: Protein cofactor competition regulates the action of a multifunctional RNA helicase in different pathways. RNA Biology 13 (3), S. 320 - 330 (2016)
279.
Zeitschriftenartikel
Cicek, I. Ö.; Karaca, S.; Brankatschk, M.; Eaton, S.; Urlaub, H.; Shcherbata, H. R.: Hedgehog signaling strength is orchestrated by the mir-310 cluster of microRNAs in response to diet. Genetics 202 (3), S. 1167 - 1183 (2016)
280.
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Koch, H.; Raabe, M.; Urlaub, H.; Bindereif, A.; Preußer, C.: The polyadenylation complex of Trypanosoma brucei: Characterization of the functional poly(A) polymerase. RNA Biology 13 (2), S. 221 - 231 (2016)
281.
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Kirli, K.; Karaca, S.; Dehne, H. J.; Samwer, M.; Pan, K. T.; Lenz, C.; Urlaub, H.; Görlich, D.: A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. eLife 4, e11466 (2015)
282.
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Absmeier, E.; Wollenhaupt, J.; Mozaffari-Jovin, S.; Becke, C.; Lee, C. T.; Preussner, M.; Heyd, F.; Urlaub, H.; Lührmann, R.; Santos, K. F. et al.; Wahl, M. C.: The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes and Development 29 (24), S. 2576 - 2587 (2015)
283.
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Pleiner, T.; Bates, M.; Trakhanov, S.; Lee, C. T.; Schliep, J. E.; Chug, H.; Böhning, M.; Stark, H.; Urlaub, H.; Görlich, D.: Nanobodies: Site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation. eLife 4, e11349 (2015)
284.
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Crisci, C.; Raleff, F.; Bagdul, I.; Raabe, M.; Urlaub, H.; Rain, J. C.; Krämer, A.: Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins. Nucleic Acids Research 43 (21), S. 10456 - 10473 (2015)
285.
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Zaman, U.; Richter, F. M.; Hofele, R. V.; Kramer, K.; Sachsenberg, T.; Kohlbacher, O.; Lenz, C.; Urlaub, H.: Dithiothreitol (DTT) acts as a specific, UV-inducible cross-linker in elucidation of protein-RNA interactions. Molecular and Cellular Proteomics 14 (12), S. 3196 - 3210 (2015)
286.
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Sharma, K.; Hrle, A.; Kramer, K.; Sachsenberg, T.; Staals, R. H. J.; Randau, L.; Marchfelder, A.; van der Oost, J.; Kohlbacher, O.; Conti, E. et al.; Urlaub, H.: Analysis of protein–RNA interactions in CRISPR proteins and effector complexes by UV-induced cross-linking and mass spectrometry. Methods 89, S. 138 - 148 (2015)
287.
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Port, S. A.; Monecke, T.; Dickmanns, A.; Spillner, C.; Hofele, R.; Urlaub, H.; Ficner, R.; Kehlenbach, H.: Structural and functional characterization of CRM1-Nup214 interactions reveals multiple FG-binding sites involved in nuclear export. Cell Reports 13 (4), S. 690 - 702 (2015)
288.
Zeitschriftenartikel
Sakin, V.; Richter, S. M.; Hsiao, H. H.; Urlaub, H.; Melchior, F.: Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 ligase complex. Journal of Biological Chemistry 290 (39), S. 23598 - 23602 (2015)
289.
Zeitschriftenartikel
Boesler, C.; Rigo, N.; Agafonov, D. E.; Kastner, B.; Urlaub, H.; Will, C. L.; Lührmann, R.: Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5‘ splice site. RNA 21 (11), S. 1993 - 2005 (2015)
290.
Zeitschriftenartikel
Diaz, S. A.; Malonoski, A. P.; Susumu, K.; Hofele, R. V.; Oh, E.; Medintz, I. L.: Probing the kinetics of quantum dot-based proteolytic sensors. Analytical and Bioanalytical Chemistry 407 (24), S. 7307 - 7318 (2015)
291.
Zeitschriftenartikel
Salat , D.; Winkler, A.; Urlaub, H.; Gessler, M.: Hey bHLH proteins interact with a FBXO45 containing SCF ubiquitin ligase complex and induce its translocation into the nucleus. PLOS One 10 (6), e0130288 (2015)
292.
Zeitschriftenartikel
Kuvardina, O. N.; Herglotz, J.; Kolodziej, S.; Kohrs, N.; Herkt, S.; Wojcik, B.; Oellerich, T.; Corso, J.; Behrens, K.; Kumar, A. et al.; Hussong, H.; Urlaub, H.; Koch, J.; Serve, H.; Bonig, H.; Stocking, C.; Rieger, M. A.; Lausen, J.: RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation. Blood 125 (23), S. 3570 - 3579 (2015)
293.
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Kadavath, H.; Hofele, R. V.; Biernat, J.; Kumar, S.; Tepper, K.; Urlaub, H.; Mandelkow, E.; Zweckstetter, M.: Tau stabilizes microtubules by binding at the interface between tubulin heterodimers. Proceedings of the National Academy of Sciences of the United States of America 112 (24), S. 7501 - 7506 (2015)
294.
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Cass, S. D. B.; Haas, K. A.; Stoll, B.; Alkhnbashi, O. S.; Sharma, K.; Urlaub, H.; Backofen, R.; Marchfelder, A.; Bolt, E. L.: The role of Cas8 in type I CRISPR interference. Bioscience Reports 35 (3), e00197 (2015)
295.
Zeitschriftenartikel
Kost, N.; Kaiser, S.; Ostwal, Y.; Riedel, D.; Stützer, A.; Nikolov, M.; Rathke, C.; Renkawitz-Pohl, R.; Fischle, W.: Multimerization of Drosophila sperm protein Mst77F causes a unique condensed chromatin structure. Nucleic Acids Research 43 (6), S. 3033 - 3045 (2015)
296.
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Oellerich, T.; Mohr, S.; Corso, J.; Beck, J.; Döbele, C.; Braun, H.; Cremer, A.; Münch, S.; Wicht, J.; Oellerich, M. F. et al.; Bug, G.; Bohnenberger, H.; Perske, C.; Schütz, E.; Urlaub, H.; Serve, H.: FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation. Blood 125 (12), S. 1936 - 1947 (2015)
297.
Zeitschriftenartikel
Jorrin-Novo, J. V.; Pascual, J.; Sanchez-Lucas, R.; Romero-Rodriguez, M. C.; Rodriguez-Ortega, M. J.; Lenz, C.; Valledor, L.: Fourteen years of plant proteomics reflected in Proteomics: Moving from model species and 2DE-based approaches to orphan species and gel-free platforms. Proteomics 15 (5-6), S. 1089 - 1112 (2015)
298.
Zeitschriftenartikel
Lin, T. Y.; Voronovsky, A.; Raabe, M.; Urlaub, H.; Sander, B.; Golas, M. M.: Dual tagging as an approach to isolate endogenous chromatin remodeling complexes from Saccharomyces cerevisiae. Biochimica et Biophysica Acta - Proteins and Proteomics 1854 (3), S. 198 - 208 (2015)
299.
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Timm, T.; Lenz, C.; Merkel, D.; Sadiffo, C.; Grabitzki, J.; Klein, J.; Lochnit, G.: Detection and site localization of phosphorylcholine-modified peptides by NanoLC-ESI-MS/MS using precursor ion scanning and multiple reaction monitoring experiments. Journal of the American Society of Mass Spectrometry 26 (3), S. 460 - 471 (2015)
300.
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Wohlgemuth, I.; Lenz, C.; Urlaub, H.: Studying macromolecular complex stoichiometries by peptide-based mass spectrometry. Proteomics 15 (5-6), S. 862 - 879 (2015)
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