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The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes and Development 253.
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Nanobodies: Site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation. eLife 254.
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Dithiothreitol (DTT) acts as a specific, UV-inducible cross-linker in elucidation of protein-RNA interactions. Molecular and Cellular Proteomics 256.
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Analysis of protein–RNA interactions in CRISPR proteins and effector complexes by UV-induced cross-linking and mass spectrometry. Methods 257.
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Structural and functional characterization of CRM1-Nup214 interactions reveals multiple FG-binding sites involved in nuclear export. Cell Reports 258.
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Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 ligase complex. Journal of Biological Chemistry 259.
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Probing the kinetics of quantum dot-based proteolytic sensors. Analytical and Bioanalytical Chemistry 261.
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Tau stabilizes microtubules by binding at the interface between tubulin heterodimers. Proceedings of the National Academy of Sciences of the United States of America 264.
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35 (3), e00197 (2015)
The role of Cas8 in type I CRISPR interference. Bioscience Reports 265.
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FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation. Blood 267.
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Fourteen years of plant proteomics reflected in Proteomics: Moving from model species and 2DE-based approaches to orphan species and gel-free platforms. Proteomics 268.
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Dual tagging as an approach to isolate endogenous chromatin remodeling complexes from Saccharomyces cerevisiae. Biochimica et Biophysica Acta - Proteins and Proteomics 269.
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Detection and site localization of phosphorylcholine-modified peptides by NanoLC-ESI-MS/MS using precursor ion scanning and multiple reaction monitoring experiments. Journal of the American Society of Mass Spectrometry 270.
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Studying macromolecular complex stoichiometries by peptide-based mass spectrometry. Proteomics 271.
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Quantitative mass spectrometric profiling of cancer-cell proteomes derived from liquid and solid tumors. Journal of Visualized Experiments 272.
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The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nature Structural and Molecular Biology 273.
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Modulation of TCR responsiveness by the Grb2-family adaptor, Gads. Cellular Signalling 274.
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11 (8), S. 1072 - 1082 (2014)
Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family. RNA Biology 275.
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Effects of mycophenolate mofetil on kidney function and phosphorylation status of renal proteins in Alport COL4A3-deficient mice. Proteome Science 276.
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RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus. Molecular Cell 277.
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11 (10), S. 1064 - 1070 (2014)
Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins. Nature Methods 278.
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Separation methodology to improve proteome coverage depth. Expert Review of Proteomics 279.
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Biophysical and biochemical analysis of hnRNP K: Arginine methylation, reversible aggregation and combinatorial binding to nucleic acids. Biological Chemistry 280.
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Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Science 281.
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Clathrin heavy chain plays multiple roles in polarizing the Drosophila oocyte downstream of Bic-D. Development 282.
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28 (7), S. 749 - 764 (2014)
The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation. Genes and Development 283.
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A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-derived RNAs (crRNAs) in Haloferax volcanii. Journal of Biological Chemistry 285.
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20 (3), S. 406 - 420 (2014)
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Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. EMBO Journal 287.
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Cutting edge: Feed-forward activation of phospholipase C gamma 2 via C2 domain-mediated binding to SLP65. Journal of Immunology 289.
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The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9. Journal of Biological Chemistry 290.
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Structure and RNA-binding properties of the Not1-Not2Not5 module of the yeast Ccr4-Not complex. Nature Structrural and Molecular Biology 291.
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Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases. Mitochondrion 292.
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Insights into the activation of the helicase Prp43 by biochemical studies and structural mass spectrometry. Nucleic Acids Research 293.
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Increased proteome coverage by combining PAGE and peptide isoelectric focusing: Comparative study of gel-based separation approaches. Proteomics 294.
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33 (20), S. 4128 - 4137 (2013)
The heme a synthase Cox15 associates with cytochrome c oxidase assembly intermediates during Cox1 maturation. Molecular and Cellular Biology 295.
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Structural analysis of the yeast Dhh1-Pat1 complex reveals how Dhh1 engages Pat1, Edc3 and RNA in mutually exclusive interactions. Nucleic Acids Research 298.
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Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription. Cell Reports 299.
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Convergent chemical synthesis of histone H2B protein for the site-specific ubiquitination at Lys34. Angewandte Chemie-International Edition 300.
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Choroid plexus transcytosis and exosome shuttling deliver folate into brain parenchyma. Nature Communications