News

Lab News on Twitter (since 2017)

November 11, 2022

What a great evening. Thanks for coming, @JoeMillerJr! https://t.co/UnkSQbTWiZ

November 10, 2022

Looking forward to the panel discussion on enlightenment & the future of democracy. https://t.co/T1DOFARh3U

November 07, 2022

This is so great and so well deserved, congratulations to Dirk! https://t.co/I3wckDltfM

November 07, 2022

Important news: regulations to limit energy prizes in Germany will apply to scientific institutions! Many thanks to everyone who helped making this possible. @Leopoldina @BMBF_Bund https://t.co/rGP44HWpyX

November 06, 2022

Really great video on exoplanets featuring Max Planck colleague @lkreidberg @mpi_astro https://t.co/GBgYmS65lD

November 05, 2022

Although RNA exit path is wrong and many factors are missing, this movie gives a great impression of how RNA polymerase II copies genes to produce mRNA. https://t.co/bfXVKvfRmp

November 05, 2022

Looking forward to discuss PLANETARY HEALTH @Falling_Walls On Nov 8 at 4pm in Berlin. Register for free livestream: https://t.co/TCweTlAc10 https://t.co/DX2ovQadhu

November 04, 2022

Wonderful event with Antje Boetius @AWI_de on her life exploring the deep sea and addressing global challenges. https://t.co/zaJ5THrTDn

November 03, 2022

The place where gravitational wave physics started. Great opportunities for the future, incl. space detector LISA and synergy with quantum computing. https://t.co/DJAIoHpGpU

November 02, 2022

Many congratulations to @GargGaurika who passed her PhD defense, great manuscript on co-transcriptional pre-mRNA capping! https://t.co/f68YFfmcN6

October 28, 2022

Here is the current lab! From January 1st coordinated by @lidschreiber with teams of project leaders @EOberbeckmann @c_dienemann and Kristina Zumer https://t.co/B4nDHJ47F5 https://t.co/WIIW8MFr58

October 27, 2022

17th Cramer lab retreat featuring @drosoigmm @SchurLab @jankosinski and Maria Sokolova. https://t.co/mpDh6822my

October 25, 2022

Thanks to @LouisJeantetFDN for producing this video on our work: https://t.co/DyMGsQxkUR Featuring @Zhang_Suyang @MRC_LMB @isaac_fianu @HaiboWang36 @MariekeOudelaar @Stefan_W_Hell @mpi_nat and others. https://t.co/vO0SonqLjc

October 25, 2022

At the interface to biology, the @MpiciPotsdam invents bioinspired materials and a sustainable future of chemistry. https://t.co/pFLBBd5jew

October 25, 2022

It is one thing to hear about the fascinating nature of gravity but seeing a movie of two black holes merging is mind-blowing. https://t.co/KBEhD4bQeY

October 25, 2022

Insights into gene dose: mRNA and protein abundance scales allometrically with ploidy, i.e. tetraploid cells show only threefold increase in protein abundance. Glad we could contribute to this study by the Storchova lab. https://t.co/9Uw93ymvZY

October 24, 2022

Much looking forward to host Antje Boetius from Wegener Institute and @MarineMicrobio at Göttingen, join the live stream! https://t.co/YSA5dg6QEe

October 24, 2022

Plant science leads to fundamental biological insights and biotech applications. But it is also key to ensure food production and to obtain biomass for sustainable chemistry. Thanks for the warm welcome! https://t.co/TCE4qOOdt3

October 20, 2022

Looking forward to moderate the discussion! https://t.co/FEc3l8hJyq

October 18, 2022

Nice description of our lab's interdisciplinary research in the new issue of the Max Planck magazine. English version will follow. https://t.co/H7Ri3lBHY2 https://t.co/6GrrhL8Qw3

October 17, 2022

Ulrich Nauber organized art exhibitions at our institute @mpi_nat for 20 years! Great outreach as science and art are close relatives. https://t.co/mEPNAYO6Td https://t.co/dybUstMq12

October 16, 2022

Science enabled the development of tests, vaccines & drugs to fight SARS-CoV2. We must support science during the current crisis to be prepared for an unknown future. https://t.co/mo8pdnNmok

October 16, 2022

Help needed: Anyone knows the artist „C. Seeberger“ who drew this beautiful portrait of Max Planck in 1934? Just obtained this ‚lost’ original artwork from a colleague. https://t.co/flxhCkwjnG

October 15, 2022

@mkMellon I loved dreaming about densities and often figured out correct structural interpretations during sleep.

October 12, 2022

Spectacular talks by Sahin, Türeci and Kariko (on how mRNA vaccines became possible) were followed by a wonderful ceremony and dinner @LouisJeantetFDN in Geneva https://t.co/TGbwz17q7c

October 09, 2022

Glad to live in a country that can attract and foster brilliant minds like Svante Pääbo. https://t.co/FQMVJjKZki

October 08, 2022

„fund the best research despite the crisis“ - important interview on German radio @DLF with Max Planck colleagues Ute Frevert and @peterseeberger https://t.co/XSDRCgXHuy

October 05, 2022

Looking forward to give the Fred Richards Lecture at Yale today: "Transcription of the Genome" https://t.co/tAeZ8mH1JV via @yalemed

October 03, 2022

Many, many congratulations to our @maxplanckpress colleague Svante Pääbo, on receiving this year‘s Nobel Prize in Physiology or Medicine! It is a great recognition of Svante‘s pioneering work and visionary leadership. Glad I could just visit @MPI_EVA_Leipzig, the place to be. https://t.co/hyEW5xPvK6

September 29, 2022

Some spontaneous thoughts on the science of the future, on our working culture and on the dialogue with the general public. https://t.co/BzDCAjK3qF

September 29, 2022

Some remarks on science communication and why we invite scientists to the upcoming literature festival at Goettingen. In German though. https://t.co/LE3yKS6tbq https://t.co/DrTs7wJHO9

September 28, 2022

So happy we were involved in this incredible work by Julia Mahamid‘s lab visualizing translation at atomic detail inside cells by cryo-ET. https://t.co/SrlUcoTS7O

September 23, 2022

Important message by the president of the German National Academy @Leopoldina today: high energy prizes will hurt research and endanger science. https://t.co/z4NINYBi5g via @derspiegel https://t.co/O4qeB5gEX8

September 22, 2022

What an honor to speak af this symposium with @erin_schuman, Catt try ol Robinsson, Ugur Sahin, Özlem Türeci and Katalin Kariko. https://t.co/Sf4Ry2J2FB

September 22, 2022

Saying goodbye to @YingChen_P and @KokicGoran who both take positions. Many thanks for the great contributions and many congratulations! Hopefully this is not the last rooftop barbecue this year. https://t.co/PMM7bmsjgO

September 22, 2022

Many congratulations, Tony and @HymanLab! https://t.co/qaY1DsXZ8d

September 22, 2022

First structural insights into how a NON-coding RNA promoter is recognized and opened by Pol II - without TFIIH but using the specialized factor SNAPc. Great work by @vasan06 in collaboration with @VanniniLab https://t.co/KI6ZvG5mGQ https://t.co/TsyStoIWKW

September 22, 2022

Wonderful opportunities to develop the life sciences and for interactions with @LMU_Muenchen @LMU_Uniklinikum @BioM_Munich @GeneCenter_LMU https://t.co/rs0d0qkvNL

September 22, 2022

The new @MPIforBI studies the mystery of biological intelligence at two sites south of Munich, our life sciences campus in Martinsried and Seewiesen, where this beautiful lake and surroundings allow for animal observation in a natural habitat. https://t.co/6OwIrv9q9A

September 18, 2022

Learned more on where we stand with quantum computing at the amazing @MPI_Quantum. In the current hype it remains open which technology will prevail to ‚store’ qubits - but it is clear QC will be superior to traditional computing for several applications. https://t.co/2DkT9r2F1e

September 16, 2022

How do animals interact, move globally and behave collectively? A fascinating combination of biology, technology and computing unravels many secrets. @MPI_animalbehav hosts outstanding research group leaders with unconventional ideas! https://t.co/SxKGJQEZpG

September 16, 2022

Exciting to meet @zieglerphoto1 today @MPI_animalbehav, who obtained this year‘s World Press Photo Award for Nature, congratulations! https://t.co/xcB1RGyKFA

September 15, 2022

In direct neighborhood of @MPE_Garching, the MPI for Astrophysics focuses on theoretical work to understand the origins of the universe and the development of galaxies and stars. https://t.co/fzmZZRl5od https://t.co/yRJtO06332

September 15, 2022

How do they know the plasma inside the Tokamak fusion reactor is at 100 Mio degrees? They built this huge „thermometer“ @PlasmaphysikIPP. And they made the heat shield of tungsten, an important contribution to @iterorg https://t.co/nRrQOQ38z3

September 15, 2022

Movies of stars accelerated by black holes, maps of dark matter in the universe obtained with X-ray detectors in space, and chemistry on distant planets! https://t.co/NoQTnazxlD

September 14, 2022

Looking forward to host Antje Boetius, Özlem Türeci and Ugur Sahin this year! https://t.co/1tr27OpAEh

September 14, 2022

Founded by Einstein and reestablished by Heisenberg the MPI for Physics is world-leading in particle physics. The insitute was also instrumental in bringing to life the MPI for Astrophysics @PlasmaphysikIPP @MPE_Garching https://t.co/tEWiP4zsSb https://t.co/ONHcykFZ0q

September 09, 2022

Deeply impressed by the work @MaxAnthropology, aimed at understanding human cultures around the world. Researchers often spend a full year abroad. Also great outreach activities: https://t.co/y26gvEWq45 https://t.co/50cM7gPDpu

September 08, 2022

Facing questions by students on climate change and personalized medicine: it is one thing to develop technologies and therapies, but we also have to change the way we live. https://t.co/s2hAq9RXNk

September 08, 2022

Mathematics is often the key to enable breakthroughs in others disciplines, not only in biomedicine or physics, but increasingly also in the social sciences and beyond. This becomes obvious seeing the many interactions of @mpiMathSci with other institutes. https://t.co/TVhRcAeEH9

September 07, 2022

Where paleogenetics was developed and human history is lined out in an unprecedented way. @MPI_EVA_Leipzig https://t.co/Yfn2yeq08j

September 06, 2022

Astonishing encounters with our close relatives at the Wolfgang Köhler Center, the largest primate observation research center, hosting 50 animals. A collaborative project of @MPI_EVA_Leipzig & @Zoo_Leipzig. https://t.co/DIjwMfaIW6

September 05, 2022

What makes us human? Perception, language, learning and memory are focus areas at the MPI for human cognitive and brain sciences in Leipzig. Home of @MPS_cog. https://t.co/7c3DF9Kfsm https://t.co/WqVNYfBMYx

September 05, 2022

What an honor to speak in a symposium with such distinguished colleagues https://t.co/QDdc78Otqv

September 05, 2022

Thank you for hosting us and all the best for the future! https://t.co/Mmh6MpI3fI

September 04, 2022

After visiting the first 15 institutes, it is clear many postdocs wish to have advice on alternative career paths. Please use offers by @maxplanckcareer and provide feedback. @MPGpostdocnet https://t.co/9Gjy1eeuR3

September 02, 2022

Many congratulations, Tony! https://t.co/H8lLVGAaOj

September 02, 2022

Great to see how the 111-year old MPI for Medical Research develops, incl. the planned new building at the Neckar river in Heidelberg. For me, it will always be connected to the introduction of synchrotron radiation to structural biology by Ken Holmes. https://t.co/TrhrciW2Ek https://t.co/tPRpZMnmOp

September 01, 2022

The only place on our planet to do chemistry under the conditions of interstellar clouds: the MPI for Nuclear Physics next to @embl in Heidelberg. Colleagues here also study mysterious dark matter and other phenomena that are well beyond my understanding. https://t.co/8TJ84JcQZW https://t.co/1YYvTaydRZ

September 01, 2022

The workshops @mpi_astro build instruments for telescopes icl. @NASAWebb, allowing colleagues to study exoplanets and the birth of galaxies and planets. Touching fundamental questions of our existence. https://t.co/hnUVWxoAAR

August 31, 2022

So obvious here how science can help make the world a better place. Peace efforts in Sudan, constitutional advice for states in Latin America or global animal rights: so many important implications of the research carried out @MPILheidelberg - thank you for these insights! https://t.co/lLZiNB7BIn

August 27, 2022

Great to be back and meet several alumni who present stories from their labs! https://t.co/fIQOcCyPqq

August 27, 2022

The program for our Literature Festival #Literaturherbst is out, including Özlem Türeci and Ugur Sahin of BioNTech on November 02, presenting „Project Lightspeed“ - the story of how the first corona vaccine became possible. https://t.co/IxYYzJi8BL https://t.co/8nKXjR0UZj

August 26, 2022

@GiuCali_ @CSHL @sroka_martyna @CAMarshall480 @cshlmeetings What a wonderful colleague, it all started with crystallography and RNA

August 26, 2022

I learned, amongst other things, how analysis of a sample from 2300 water depth questions our current tree of life and understanding of eukaryote evolution. So much to be discovered in the ocean. Thank you for the stimulating discussion. https://t.co/vRM2HqGA7l

August 25, 2022

Located in Hamburg, @MPIPRIV has unique expertise in private law for numerous countries, competence centers for China and the islamic world, amongst others, and an impressive library that attracts ~1000 guest researchers each year. https://t.co/8Ea2FW3F71

August 24, 2022

What a privilege to be part of the first event held in the brand-new building @MPSDHamburg - the place to be for studying the structure and dynamics of matter on a large campus with strong partners @CFEL_Hamburg @unihh @desy @CssbHamburg @embl https://t.co/tw05lkqQvV

August 24, 2022

Moving to visit the place where the foundations were laid to proof that global warming is a result of human activity, eventually leading to the Paris Agreement in 2015. Today continued outstanding research on climate modeling with big data, really critical for our future. https://t.co/JHpAQsXIi3

August 23, 2022

Impressed by @MPI_Muenster after meeting Dietmar Vestweber, @WickstromLab and @ralfhadams. Biomedical research including work on tissue morphogenesis and dynamics. https://t.co/PfgTzl5BJb

August 18, 2022

A glimpse of the future when visiting the MPI for Security and Privacy - topics range from cryptography to digital wellbeing. Strong local partner @ruhrunibochum https://t.co/d6GQ3b34tg

August 18, 2022

The @mpimoph not only conducts leading research in cellular, structural and chemical biology; it also enables large-scale robotic compound screens and lead discovery through COMAS and LDC. https://t.co/sMZIDUciE1

August 17, 2022

Good-bye to @Zhang_Suyang & wishing her all the best for her lab @MRC_LMB - she solved the first transcription-splicing structure & will continue on this. https://t.co/QZjxRDJnIg https://t.co/HLAJLWW59u

August 17, 2022

Very impressed by the MPI for Mathematics in the center of Bonn: 4 colleagues (of whom 2 obtained the Fields Medal) attract hundreds of guest scientists from around the globe each year. https://t.co/muw2k3lQhJ

August 12, 2022

@MPI_Metabolism not only does great science but also builds bridges to the hospital and creates strong synergy with the neighboring @MPIAGE https://t.co/rkv69QJV7v

August 12, 2022

Thank you for hosting us! Great discussions on how to best support our group leaders. https://t.co/7rDZDB0Rp5

August 11, 2022

Fascinating start of our tour of Max Planck Institutes in Bonn: Behavioral law and economics study how we judge and take decisions https://t.co/h9CjcKCFMm https://t.co/AzWNedUsEc

July 25, 2022

Sharing the piece I wrote on the occasion of the 100th anniversary of Franklin‘s birth: https://t.co/6cos60sqeO https://t.co/STkk7Ws32b

July 19, 2022

#Nucleosome passage by Pol II: H2A/H2B loss, backtracking and TFIIS-mediated reactivation. Finished in a transatlantic collaborationbetween @LucasFarnung @MoritzOchmann @GargGaurika @seyvos https://t.co/dTmqSNMHnm https://t.co/HZfOyOxn7h

July 15, 2022

Honored to witness today how Planck joins Gauss at the hall of fame ‚Walhalla‘ in Bavaria https://t.co/07bnNXbOd8

July 14, 2022

Feels surreal to hold a copy of Galileo Galileis ‚Discorsi‘ from 1655 in hands. One of the treasures of @MPIWG. https://t.co/Miw3PUAvez

July 06, 2022

Many congratulations @RehlingLab, newly elected member of @EMBO! https://t.co/iQ1sHyKpy4

July 06, 2022

Thank you for the invitation, @BioM_Munich and congratulations on 25 years of the Munich Biotech Cluster. https://t.co/gFnZBt2rXK

July 01, 2022

Saying good-bye to @HaiboWang36 and wishing him all the best as a PI at @ZJU_China. Remembering his wonderful work on chromatin-associated factors: https://t.co/q6HbhPcA6v https://t.co/L6ylxm92zV https://t.co/74gE4xiVZr https://t.co/R7LTHzrjo4

July 01, 2022

So well deserved. @KokicGoran solved much of the mystery of TCR. All the best for the future! https://t.co/prJksS9LKG

June 27, 2022

Explaining gene transcription in German TV in 13 minutes… https://t.co/3t4F9CWJJu https://t.co/INSUl5WLGv

June 23, 2022

Honored to serve science and society as next president of @maxplanckpress and looking forward to visit our 85 institutes and prepare for my term. https://t.co/f8LliT2nWs

June 22, 2022

Very grateful to past and present lab members for their contributions. Wonderful to see many of them excel in their own labs. https://t.co/gK0gJLNZW0

June 20, 2022

What a memorable event, and so great to share with two close colleagues and friends. https://t.co/A8Ue4eDodh

June 17, 2022

Congratulations @msanderlab - and all the best to @MDC_Berlin https://t.co/6iMQhv6HwL

June 12, 2022

Looking forward to speak at the Aminoff Symposium in Stockholm on Tuesday. Programm: https://t.co/TpKrSSrJid https://t.co/8eetRgvj29

June 05, 2022

Very impressed by the newly opened @ForumWissenGoe - a place teaching the scientific approach @uniGoettingen @thegoecampus https://t.co/fMWYCk9x5N

June 04, 2022

Honored to join the Berlin-Brandenburg Academy of Sciences and Humanities. https://t.co/vgh35mThS7

June 03, 2022

Many congratulations to Eusra Mohammad who just passed her PhD defense! Fine contributions to multiomics analyses of transcription-related CDKs. https://t.co/gpCTjhL2kk

June 02, 2022

Looking forward to discuss the future of biomedicine at Munich on July 5-6. https://t.co/feK09HwoW4 @BioM_Munich https://t.co/LcYivwm6eb

June 01, 2022

Thanks @plaschka_lab @AlexanderStark8 @IMPvienna for organizing a great day of exciting science. https://t.co/epmSN1hLPg

May 27, 2022

Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells. Fine collaboration of @LeXiong @lidschreiber @taras_velychko @LCaizzi with Schöler lab. https://t.co/paVNCaoK3z @eLife

May 26, 2022

Thanks for the warm (!) welcome and interesting science https://t.co/Cylo1lfrcz

May 25, 2022

Much looking forward to visit @IMPvienna, give the Birnstiel lecture and meet many colleagues incl. @plaschka_lab @AlexanderStark8 https://t.co/1TPFla7ES3

May 19, 2022

Finally big lab party again https://t.co/zHnWUAqzYy

May 17, 2022

Structures of nucleosome arrays suggest that H1 binding depends on length & trajectory of linker DNA. This can explain why arrays with short spacing are H1-depleted & suited for transcription. @mdombro_ @Sveta_Dodonova @c_dienemann Paper: https://t.co/Mr6c0WO5WS https://t.co/ws2N9cl30O

May 12, 2022

Looking forward to host Titia de Lange from @RockefellerUniv for our Bonhoeffer Award Lecture @mpi_nat next Tuesday. https://t.co/srGVXVey5e https://t.co/wmrQ17Hfc3

May 11, 2022

So great to have @mleptin as president of @ERC_Research, congratulations! https://t.co/UD2LVUDlRY

May 10, 2022

mRNA vaccines became possible based on decades of basic research. Celebrating @Helmholtz_HIRI @Helmholtz_HZI with @JoergLab at Würzburg residence. https://t.co/XC0Oyo1np2

May 08, 2022

#Ukraine️ national colors east of #Göttingen campus. https://t.co/L6vog1NK4T

May 08, 2022

„I come with a wish: foster diversity and understanding“ - Andreas Görgen (BKM) at the grand opening of the Göttingen Literaturhaus. https://t.co/bXE1FR9jhK

May 04, 2022

The talks given at the @Leopoldina #COVID symposium are now available online: https://t.co/wiyQrAcwaG

April 29, 2022

Thanks to colleagues in the DNA repair field for the invitation. In the future, @KokicGoran may be a frequent participant. https://t.co/vZ5Z1tlDiV

April 27, 2022

Huge Thank You to Steven Cusack and best of luck to Kristina Djinović-Carugo! EMBL Grenoble is close to my heart - great memories from PhD times. https://t.co/0hoy5yF8Ia

April 26, 2022

Looking forward to host our new Federal Minister of Science @starkwatzinger @mpi_nat for a round table discussion on May 5. https://t.co/OhqD6GYrgC

April 22, 2022

Saying good-bye to @mdombro_ with a rooftop barbeque! https://t.co/RW4qaTUpM3

April 19, 2022

Here is the future! https://t.co/I3yWRqBRTf

April 07, 2022

Great honor to give this lecture in memory of our colleague Elisa Izaurralde. https://t.co/CzrnLGBDke

April 03, 2022

Congratulations to @hauke_hillen for receiving the Engelhorn Research Award 2022 tonight in Munich! https://t.co/PJD5o6fhyQ

April 02, 2022

Congratulations to former lab member Kayo Nozawa who just started her own lab at Tokyo Institute of Technology @NozawaL https://t.co/sPzvIb4pUm

March 29, 2022

Polymerase in action. Looking forward to the TV recording later tonight. https://t.co/lmuxCFZCeU

March 21, 2022

The talks of the cryo-EM workshop at Academia dei Lincei are now online. Keynote lecture starts at 3.01: https://t.co/TKtJtQ9YZB https://t.co/o50T38jHE7

March 18, 2022

Looking forward to give the closing keynote at the cryo-EM workshop of the ACCADEMIA LINCEI today at 5.15 pm CET. Livestream: https://t.co/yYvCobHQ3o https://t.co/yadxknnQsK

March 18, 2022

Looking forward to close cooperation. https://t.co/ud8GxBiV2T

March 17, 2022

TT-seq measures synthesis and degradation of Alu retrotransposons. Glad we could contribute to this fine work of the Tresch lab. https://t.co/sa9ZdLKyZe https://t.co/Wszjy25sji

March 16, 2022

Save the date: EMBL Conference Transcription and Chromatin, taking place August 27-30, 2022 in Heidelberg. So much looking forward to meet close colleagues in the field again. https://t.co/zRW1G95x4E via @embl

March 07, 2022

@AsifaAkhtar1 Many congratulations, Asifa!

March 04, 2022

A famous alumnus of the University of #Odessa, #Ukraine, is George Gamow. He later worked at Göttingen and contributed to solving the genetic code. https://t.co/xiHBnNyoad

February 26, 2022

‘A step to nowhere’: Russian scientist organizes protest of Ukraine war https://t.co/NywT60ahbQ

February 21, 2022

Happy we could contribute to this new study from the lab of Jussi Taipale that uses massively parallel reporter assays to unravel sequence determinants for transcription activity and transcription factor function. https://t.co/nVkAL7ViOx

February 12, 2022

3 years ago I could visit this field station at the Beagle Channel near Ushuaia and understood a little better how traveling around Patagonia may have helped Darwin to come up with his revolutionary ideas. #DarwinDay https://t.co/IrFOwtV4te

February 09, 2022

The lab of ⁦@ZStorchova⁩ shows that mRNA and protein abundance scales allometrically with cell ploidy. Glad we could contribute. https://t.co/Gj6IbuztV5

February 04, 2022

On the shoulders of giants: Ken Holmes started as a PhD student with Rosalind Franklin and later introduced synchrotron radiation to X-ray crystallography, what a step. https://t.co/k7O690plB8

February 02, 2022

Movie by @KokicGoran shows how a protein complex (Pol II TCR complex) gets targeted by ubiquitination. https://t.co/yxFuhhUXpF https://t.co/sBSVLYIzM5

February 02, 2022

Great to see Roger still uses the initial ribbon model image of the core Pol II crystal structure from 2000 in his talks. Great memories. https://t.co/m14cD6kQv8

February 01, 2022

„Anyone can identify Karikó in retrospect, given her persistence and her eventual discoveries. But what do we do right now to find the 2022 versions of Karikó…“ https://t.co/AITd6cBElD via @statnews

February 01, 2022

This one of the top Max Planck projects in this decade. https://t.co/12n7kCrnw3

January 19, 2022

Congratulations to my colleagues @embl @emblebi on this ambitious and timely program! Best of luck! https://t.co/zZyujvslu4

January 19, 2022

Congratulations to the new life science factory that was just opened at Goettingen. https://t.co/vC4vhEorVB

January 18, 2022

After two years of zoom I much look forward to meeting colleagues again and hope we can travel to this exciting meeting on DNA repair mechanisms. https://t.co/Fj7DOZOTGr

January 15, 2022

Podcast on molecular evolution by Susanne Rostosky (German): https://t.co/2n2KJHyQm5 Happy I could contribute with our old study (Lehmann et al. Nature 2007): https://t.co/QzOKi5OThu

January 07, 2022

New interview on the latest on #SARS_CoV_2 #Covid_19 drugs #remdesivir #Molnupiravir #paxlovid (in German). Thanks to @gunnar_heine and colleagues. https://t.co/e4p5bIiJdX https://t.co/V1FdAiiEeU

January 05, 2022

The talk by Maja Göpel @beyond_ideology held on Nov 2, 2021 at #Literaturherbst is now available online (in German) at https://t.co/02K3m1xfGe https://t.co/LFt3zkjP12

January 01, 2022

It is an honor to serve as managing director of our new Max Planck Institute from today. I thank my colleagues for their trust and look forward to an exciting year. https://t.co/VvhPYOQWpu

December 17, 2021

Many congratulations Le Xiong for passing the PhD defense and all the best for the future! https://t.co/wWlqLXp1lt

December 16, 2021

Save the date: "Transcriptional regulation: Chromatin & RNA polymerase" Sept. 29–Oct. 2, 2022 in Snowbird, Utah. https://t.co/SSzLLWTDHy

December 09, 2021

So sad to say good-bye to Christina, Paulina, Felix, Sandra and Marc… but very happy they all found very good jobs. Many thanks indeed and all the best for the future! https://t.co/gGl0GMXf80

December 01, 2021

Marco Dombrowski passed his defense today, many congratulations and all the best for the future! https://t.co/5iHuN7co4V

November 30, 2021

This is so well-deserved, many congratulations! https://t.co/UORKWRs4DC

November 27, 2021

#molnupiravir will not be a game changer in fighting #SARSCoV2 as its efficacy is low. Highlights need for developing new #antivirals targeting #coronavirus polymerase. https://t.co/GLDwNLYxdm

November 25, 2021

"Free, curiosity-driven basic research is the foundation of public research funding" - an important statement of the new German coalition #Koalitionsvertrag https://t.co/TqcT7L5ETg

November 13, 2021

Extremely sad. Terrible we lost such a wonderful and always supportive colleague @thegoecampus. My thoughts are with Ulf Diederichsen‘s family. https://t.co/qYhDjkiqSg

November 11, 2021

Great to see how Integrator embraces the paused transcription complex to engage with nascent RNA and trigger Pol II attenuation. Paper by @isaac_fianu et al. edited by @dijiang319 is out @ScienceMagazine: https://t.co/hx8rb9Awly https://t.co/cbmLswOWsA

November 09, 2021

One minute of standing ovations after an incredible talk by Özlem Türeci of BioNTech on how mRNA vaccines became possible @Falling_Walls https://t.co/Kv4fakFX5t

November 08, 2021

My recent keynote “Towards a mechanistic understanding of genome regulation” @MRC_LMB is online: https://t.co/nqCJj6CGCH https://t.co/hZhnhupnZi

November 04, 2021

Much looking forward to discussing #SARS_CoV_2 replication and #COVID19 antivirals with @LoellChristiane and Christian Spahn at @Falling_Walls on November 8 in Berlin. https://t.co/SVjmE9ph6P

November 03, 2021

Lively discussion on economic and ecologic transformation yesterday night with Maja Göpel @beyond_ideology - science and society event @mpi_bpc and Literaturherbst Göttingen. https://t.co/3WOEHNlbIK

October 30, 2021

@lianafaye BioNTech?

October 27, 2021

Honored to join Ugur Sahin of BioNTech and Tzachi Pilpel @TPilpel @WeizmannScience for the Max Planck Forum on „#Covid19: From Vaccination to Medication“. Online on Nov 11, 2021 at 6.30 pm CET. https://t.co/qRQRptLedt https://t.co/FIEAgd1nOZ

October 27, 2021

Very much looking forward to host Maja Göpel next week and discuss her vision of societal and economic transformation. https://t.co/33SNmeo5wG

October 19, 2021

Our institute is hosting Tom Cech today for the Manfred Eigen Award Lecture: Cryo-EM of a telomeric complex and RNA as a regulator of epigenetic silencing https://t.co/GYdgO02bJb

October 14, 2021

The paper by @KokicGoran et al. on DNA transcription-repair coupling is now available open access: https://t.co/G2UgJx8GiL Watch the conversion of the Pol II elongation complex EC* to a repair-competent EC-TCR containing CSB, CSA, DDB1 and UVSSA: https://t.co/TSlydWOrjG

October 14, 2021

Looking forward to speak at #FallingWalls21 in Berlin November 7-9, 2021 to present our contribution to #ScienceBreakthroughs on #coronavirus #SARSCoV2 antivirals. Event information: https://t.co/dCAdHCypAs Video abstract: https://t.co/N9SdlpdMuA

October 13, 2021

New article on the current discussion on the impact of #AlphaFold on structural biology (in German): https://t.co/nf904J6lFo

October 08, 2021

Congratulations to former lab member @ClausDKuhn for obtaining a professorship at University of Bayreuth! https://t.co/WoYaCAWRqB

October 07, 2021

So happy to have a REAL group retreat again! Many people have left and taken positions and many new ones have joined. Great opportunity to rethink our science. https://t.co/7aARD4YB0w

October 06, 2021

Much looking forward to our lab retreat at Berlin starting tomorrow! Hosting as speakers rising stars @_taktas_ @MariekeOudelaar @luijsterburglab @KovtunOleksiy https://t.co/sG3RkKC30X

October 06, 2021

Good summary by @Fischblog of the chances and risks of #molnupiravir treatment of #COVID19 patients (in German). https://t.co/VJ0bzx64Qv

October 05, 2021

Congratulations, Seychelle! https://t.co/eMW09zT9Qh

October 05, 2021

Many congratulations and welcome to our new postdoc, Shen Han @s_Han7! https://t.co/yuhLGK7Erq

October 04, 2021

The program for our new seminar series is out! Looking forward to host @YuanHe_NWU @canardbruno @Beck_Laboratory @LabConti @RobKlose @AdelmanLab & Xaohua Shen @Tsinghua_Uni https://t.co/ajIFzJIiyk

October 04, 2021

The talks from the symposium at @StJude ("Bringing Chemistry to Medicine") are now available online: https://t.co/y8NgihaMH9

October 01, 2021

Encouraging results for the antiviral #molnupiravir: oral treatment of #covid19 patients reduces risk of hospitalization by ~50%. We had previously described its molecular mechanism: https://t.co/EcB9ow6cn2 https://t.co/nfckng4r4C

September 30, 2021

@NietoAngela @MichelaBertero @lorealspain @CSIC @UniversidadMH Many congratulations, Angela!

September 29, 2021

@hecklab @Pittcon @asmsnews @OmicsNL Many congratulations, Albert!

September 29, 2021

Looking forward to today‘s virtual Next Generation Biophysics Symposium @MRC_LMB @imperialcollege https://t.co/zqzldTwAQO https://t.co/wfemLwhI8Z

September 24, 2021

Congratulations to our postdoc Suyang Zhang @Zhang_Suyang for obtaining a Group Leader position @MRC_LMB! All the best! https://t.co/JzXdCwmAxF

September 17, 2021

Saying good-bye to @Sveta_Dodonova who starts her lab @embl in Heidelberg soon. Many thanks indeed & all the best for the future! We will miss you. https://t.co/zPLusLup1A

September 17, 2021

Pol II can form inactive dimers: the stalk of one Pol II copy binds the active centre cleft of the other Pol II copy, and vice versa. Maybe an inactive storage form of the enzyme? @shintoez @c_dienemann https://t.co/6OgeDMbXny https://t.co/gui7jcuvMS

September 15, 2021

@TriggerLoop The yeast work is highly appreciated and fits well but unfortunately we had to limit references due to length restrictions.

September 15, 2021

Transcription-coupled DNA repair: After a long journey, we can now see how CSA, CSB, UVSSA and CRL4 remodel the transcribing Pol II complex for ubiquitination and DNA repair. Masterpiece by @KokicGoran. https://t.co/G2UgJwR5rd https://t.co/j8p9gv7YW3

September 14, 2021

Very honored to receive the Aminoff Prize of the Royal Swedish Academy together with my close colleagues Elena Conti @MPI_Biochem and Seth Darst @RockefellerUniv. Grateful to many past and present coworkers @CramerLab, colleagues at @mpi_bpc and @maxplanckpress for all support. https://t.co/03tS7pto1J

September 14, 2021

Looking forward to this year's Literature Festival hosting Maja Göpel @beyond_ideology. You can get online tickets and practice your German - but there are also a limited number of seats available. https://t.co/7BCEFpBU8C https://t.co/JdcDpvSS4h https://t.co/ace5EFPfWq

September 14, 2021

#Molnupiravir : coding for catastrophe - very informative news&views article by Liz Campbell on recent work from Götte lab, ⁦@HoebartnerLab⁩ and us in Nature Structural & Molecular Biology https://t.co/z3nqMuuUrm

September 10, 2021

So incredible: on his 80th birthday symposium, Ernst-Ludwig Winnacker explains his PhD work on the synthesis of vitamin B12! ⁦@GeneCenter_LMU⁩ ⁦ https://t.co/glvQk1FRAb

September 06, 2021

Structural basis of RNA processing by human mitochondrial RNase P now revealed by @BhattaArjun2p and @hauke_hillen. Glad we could contribute to their newly published paper: https://t.co/lp8l62byWO

August 30, 2021

So much looking forward to the Cold Spring Harbor Mechanisms of Eukaryotic Transcription virtual meeting starting tomorrow! #moet2021 https://t.co/Rk44G2RYVZ

August 24, 2021

@royalsociety @SjorsScheres So well deserved

August 24, 2021

The #coronavirus polymerase can dimerize via its nsp7 subunit when one nsp8 subunit is lost. We speculate the antiparallel dimer facilitates template switching during sub-genomic #SARSCoV2 RNA synthesis. Thanks to team #COVID19. https://t.co/7vPRr6E8xf https://t.co/3Llq9lDWy7

August 21, 2021

B12 was the first structure I saw in 3D when I was a student at the University of Bristol in 1992. I was so taken by its beauty that I moved to crystallography. https://t.co/nclhaGLEH6

August 19, 2021

https://t.co/qRbvdPMRJi

August 19, 2021

@OWitzig Nein, Medikamente werden nur ergänzend sein, bitte vor dem Herbst dringend impfen lassen.

August 19, 2021

Good summary of our recent studies of #molnupiravir (in German) https://t.co/iFUJ3kn1Ld via @BR24

August 17, 2021

This year’s Horizons meeting organized by our young scientist community is approaching: @HorizonsMolBio @mpi_bpc https://t.co/1Gb35NJA6H

August 16, 2021

Molecular mechanisms of #corona drug candidate #Molnupiravir Free access link to paper: https://t.co/i0kRkVBKNc Press release: https://t.co/Ix6abGdlSR

August 14, 2021

Free access link for AlphaFold2 and the future of structural biology https://t.co/stutNXHvrv

August 11, 2021

#molnupiravir is a #COVID19 drug candidate that targets #SARSCoV2 polymerase and causes #coronavirus mutagenesis. In collaboration with @HoebartnerLab we provide the mechanism of this phase III #antiviral: https://t.co/EcB9ow6cn2 https://t.co/49C9z4Upvh

August 10, 2021

#alphafold2 is based on @PDBeurope and is testimony to the power of open science. The marvelous resource provided by @DeepMind and @embl @emblebi is a seminal example of how transformative research may be done to the benefit of society. https://t.co/TyxVZc0lbX

August 02, 2021

Welcome to the lab, James! https://t.co/GLS6Jej8hv

July 30, 2021

@TheresiaBauer Danke, ein wichtiger Schritt!

July 29, 2021

@CeMM_News @georg_e_winter Congratulations, Martin!

July 28, 2021

https://t.co/dXJOToribP

July 28, 2021

Many congratulations, Ernst-Ludwig Winnacker, and thank you for all your great efforts to foster excellence in European science and to promote early scientific independence in Germany! https://t.co/CcCMxhbgQf

July 27, 2021

@DrReneHeller @MPSGoettingen Welcome to Goettingen

July 24, 2021

TBP binding to a nucleosome, assisted by TFIIA. Unexpected structures and their implications by @HaiboWang36 now online: https://t.co/n7MBvRTsGZ https://t.co/1VVkEeJ54F

July 22, 2021

@TriggerLoop @ArndtLab Many thanks for writing this, Karen and Craig!

July 19, 2021

Looking forward to the Harden Conference "Machines on Genes" that takes place May 22-26, 2022. https://t.co/ZHqZGrcONm https://t.co/QcNuC4TrXn

July 16, 2021

Save the date: Sept 29-Oct 02, 2022 Transcriptional regulation: Chromatin and RNA polymerase II - ASBMB meeting in Snowbird, Utah https://t.co/SSzLLWTDHy

July 16, 2021

Finally! 1 1/2 years later we can again celebrate together in a local restaurant! https://t.co/WtFOHPgmDg

July 14, 2021

Super Elongation Complex binds RNA polymerase II lobe & protrusion to stimulate transcription allosterically. Comprehensive structure-function analysis by @YingChen_P et al.: https://t.co/J1ICd86fO2 https://t.co/WRCEGFS1Eh

July 13, 2021

Please trust in science and get vaccinated! It works: Last winter old people were vaccinated in Germany and they were protected from #SARSCoV2 in spring (@rki_de & @DIEZEIT). https://t.co/RDWHToQ4Uf

July 13, 2021

Many congratulations to @FKabinger who received a Boehringer Ingelheim Fellowship today! https://t.co/68BLIJcYGs

July 13, 2021

Looking forward to give a lecture at @UniLeipzig today at 4 pm CEST: https://t.co/rtHD3caX9h https://t.co/M3HFIQ4jmP

July 07, 2021

Celebrating 50 years of the Protein Data Bank on 20-22 Oct 2021, register now: https://t.co/K3vOVtdOZq

July 06, 2021

Sara Martins @SaraMM_4 passed her PhD defense, many congratulations! Great presentation on how splicing influences transcription, her work with @LCaizzi: https://t.co/qloGaLq6u1 https://t.co/eP0pACxJt0

July 02, 2021

Much looking forward to the virtual symposium „Bringing Chemistry to Medicine“ on July 22-23 at St. Jude. https://t.co/UWHnuiqzdF

June 29, 2021

@ewanbirney Unfortunately true

June 28, 2021

Multiomics shows that the pluripotency factor #Oct4 primarily controls enhancer activity and not accessibility. Fine collaboration of Le Xiong et al. with @Tolen13 in the lab of Hans Schöler @MPI_Muenster. Preprint: https://t.co/7jjUAvqkkA

June 24, 2021

On our YouTube channel you can now find recent lectures, special events and videos about our research. https://t.co/1HVVLqW7hP

June 22, 2021

@shengfui Warum wurde überhaupt gefragt?

June 20, 2021

We have to say good-bye to @LCaizzi, thanking her for pioneering work on the in vivo kinetics of pre-mRNA splicing and its coupling to transcription and wishing her all the best for continuing her career at Turin, Italy! https://t.co/jmw79mjhYV

June 18, 2021

PAF and SPT6 stimulate human transcription elongation in distinct ways. Whereas PAF subunit RTF1 stimulates Pol II velocity, SPT6 stimulates Pol II passage through nucleosomes. Congratulations Kristina Zumer et al.! https://t.co/PBaKf2Afyn https://t.co/joXEOvKHsd

June 15, 2021

It’s the year of the #PIC: Yeast Pol II pre-initiation complex at 2.9 Å resolution defines a unique mechanism of initial DNA opening. Tour-de-force by @S_Schilb with help from @shintoez & @c_dienemann. Download the paper here: https://t.co/LA781MSkqE https://t.co/wSrJIVQCvR

June 09, 2021

U.S. signs $1.2 bln deal for experimental #COVID19 drug #molnupiravir. We provide the molecular mechanism for free. https://t.co/e4wy78f1x1 https://t.co/8w1yjarp9S

June 09, 2021

@PoulNissen @AarhusUni Many congratulations! So well deserved.

June 08, 2021

Many congratulations to Dr. Katalin Karikó for the 2022 Vilcek Prize for pioneering vaccine research - she modified RNA to suppress its immunogenicity and expand its life time: https://t.co/0asXiaWPgY

June 08, 2021

Save the date: NEXT GENERATION BIOPHYSICS SYMPOSIUM 2021 Wednesday 29th September 2021 MRC Laboratory of Molecular Biology, Cambridge, UK https://t.co/oXlOVU9Mjg https://t.co/c1cmMq2Fdx

June 08, 2021

Looking forward to the annual molecular biology conference organized by PhD researchers at Göttingen. https://t.co/OzvwEWj21h

June 06, 2021

The new public art gallery #kunsthaus göttingen has opened! First impressions here: https://t.co/5cHNB5fSZ5 https://t.co/DTCB2xDQhM

June 05, 2021

@ABaerbock Bitte setzen sie sich für die Widerspruchsregelung ein

June 03, 2021

Our high-resolution structures of human PIC and Mediator-PIC complexes are published. We define conformational changes underlying DNA opening and suggest how Mediator activates the TFIIH kinase CDK7. https://t.co/yvpUqOZt3m https://t.co/sV4fqSNbOE https://t.co/5amgLXnopW

May 28, 2021

Chromatin remodelers use 'rulers' to set nucleosome array spacing and phasing! Glad we could contribute to this interesting work by @EOberbeckmann @KorberLab https://t.co/4AVaET8Wl4 https://t.co/FbaxA74Mv9

May 24, 2021

@OdedRechavi I recommend Magellan also, if you are interested here a short summary: https://t.co/CtXuGPo9uu

May 21, 2021

@crc_1064 Congratulations to my former colleagues in Munich!

May 21, 2021

Little is known about the biogenesis & nuclear import of RNA polymerases. We now report the structure of the import factor RPAP2 bound to Pol II. It shows RPAP2 must be displaced before transcription can start. Congratulations @isaac_fianu et al.! https://t.co/nZ7vdQsU4U https://t.co/N7QxMAcCzF

May 19, 2021

@canardbruno @nathanpsmad @SFV_France @UnivOuverte @HuetSylvestre Je suis d‘accord, il ne faut pas répéter les erreurs du passé (SARS-COV1)

May 19, 2021

@YuanHe_NWU Congratulation Yuan, so well deserved!

May 18, 2021

So much looking forward to the Mechanisms of Eukaryotic Transcription Meeting on August 31 - September 3, 2022, very unfortunately only virtual. Thanks to great colleagues Mike Levine, Jane Mellor and @NogalesLab for organizing! https://t.co/Rk44G2RYVZ

May 12, 2021

#COVID19 drug candidate #molnupiravir is incorporated by #SARSCoV2 polymerase into RNA and directs misincorporation of G or A when used as template. Structural basis of #antiviral-induced coronavirus mutagenesis. Great collaboration with @HoebartnerLab! https://t.co/8w1yjarp9S https://t.co/VgIiyRArCL

May 11, 2021

When U2 snRNP function is impaired, Pol II accumulates in the promoter proximal region and RNA synthesis activity ceases. It will be exciting to find out how cotranscriptional spliceosome assembly stimulates transcription. https://t.co/66l7SRO87o https://t.co/2bHvK80wGt

May 10, 2021

Many congratulations to @Sveta_Dodonova who will start her new lab @embl in fall! We will miss her! See Svetlana‘s new website here: https://t.co/XDK7Cgjtdd See her pioneering paper here: https://t.co/ypkUInxsGu https://t.co/tfDc3yN6Yp

May 09, 2021

50 years ago, Manfred Eigen founded our institute at Göttingen. https://t.co/0s6jXyl7f4

May 09, 2021

@pisaniferry Toujours pour l‘Europe

May 05, 2021

@neubadah Same here. Just for coronavirus papers it is different: Do everything at once.

May 03, 2021

In this paper we show with purified proteins that the Cdk8 module impairs Mediator binding to the PIC. Cdk8 kinase activity facilitates Mediator dissociation from the Cdk8 module and its binding to the PIC for transcription initiation. Led by @sarakosman. https://t.co/A5Y9eqyclZ https://t.co/b6CX4cv7UC

April 28, 2021

Congratulations to Katja Lidschreiber who will take on the position of coordinator of the new coronavirus research network COFONI. We thank her for the great work and wish her all the best for the future! https://t.co/SsbQnhRy61 https://t.co/sWxsiazW62

April 27, 2021

@BJ_Greber Peer review may not be perfect but it is the best available system to ensure scientific quality. It generally works well. The occasional outliers confirm the rule. Attempts by some journals to make peer review more transparent can avoid issues. Review for journals you publish in.

April 27, 2021

Promoter opening goes along with detachment of TFIIH from the core PIC, predicted to stop DNA translocation and enable RNA chain initiation. Great work of @S_Schilb @shintoez @vasan06 @c_dienemann Free access: PIC: https://t.co/And8iJFovs Mediator-PIC: https://t.co/OaFfresEhu https://t.co/ZM3DUvCHov

April 26, 2021

We present structures of (Mediator)-Pol II pre-initiation complexes at high resolution. Feels great to arrive at a detailed understanding, incl. conformational changes in TFIIH translocase XPB during DNA opening. PIC: https://t.co/yvpUqOZt3m Mediator-PIC: https://t.co/sV4fqSNbOE https://t.co/W5QhtynAo3

April 24, 2021

Celebrating the 50th anniversary of the Protein Data Bank @buildmodels @PDBeurope with 1000 structures of #coronavirus #SARSCoV2: https://t.co/yv1Zrkdm5u https://t.co/zoL3hXgtLY

April 19, 2021

The Warburg lecture on ‚RNA polymerases and the #COVID19 pandemic‘ is now available on the @GBM_eV website: https://t.co/jpF6R72sBS https://t.co/YhZgEY0wOX

April 16, 2021

In contrast to #Remdesivir, #Molnupiravir is orally available. It now shows promise in #COVID19 outpatients. Such #antivirals targeting #coronavirus #SARS-CoV2 polymerase likely must be given early during infection. May become useful prophylactically. https://t.co/TTK4mKZX3a

April 12, 2021

We show how the chromatin remodeller Chd1 and the histone chaperone FACT help RNA polymerase II to pass through a nucleosome. Pol II transcribes into & partially unwraps the nucleosome, enabling Chd1 & FACT to bind. Congrats @LucasFarnung! Free download: https://t.co/RQG5h5EYej https://t.co/hwVgK6U4Fp

April 05, 2021

This study by @davidwtaylorjr and Kenneth Johnson is highly consistent with our study of the molecular mechanism of #remdesivir induced stalling of #coronavirus #SARSCoV2 polymerase due to a translocation barrier: https://t.co/vv2LjM4kjT https://t.co/91hszAkYo9

April 04, 2021

@judithmwhite When was this?

April 01, 2021

@JTrittin @ramin_y @uniGoettingen @faznet @MpStephanWeil @CDUNds Göttingen spielt zudem in der Coronaforschung eine wichtige Rolle @ViolaPriesemann @snpoehlm @CramerLab

March 29, 2021

TT-seq combines short, non-perturbing 4SU labeling with RNA fragmentation to: -detect short-lived eRNA -estimate RNA synthesis & txn initiation rates -monitor txn responses -map putative enhancer landscapes -analyze enhancer cooperation Original method: https://t.co/YIbJre1fxh

March 27, 2021

Enhancers may cooperate synergistically to determine cell fate. Synergistic enhancers are defined by eRNA synthesis, depend on cell-specific TFs and differ form occupancy-defined superenhancers. Great collaboration with Graf & Söding labs. Finally out: https://t.co/en8ctYctzz https://t.co/Zwwd4R3YSo

March 24, 2021

The polymerase of #coronavirus #SARSCoV2 can adopt an alternative structure: an antiparallel dimer with only one nsp8 that may bind only one nsp13. We speculate the dimer facilitates template switching and synthesis of subgenomic viral #RNA. Manuscript: https://t.co/RiGv5eeOYr https://t.co/Vilj3ig98b

March 23, 2021

Congratulations to Alexander Rotsch for obtaining one of the prestigious Boehringer Ingelheim Fellowships! https://t.co/Zz0IRGs0yL

March 14, 2021

High conservation of the yeast (left) and human (right) Mediator-PIC assembly. TFIIH kinase also resides in similar location in yeast complex but was omitted due to mobility. Yeast: https://t.co/8ySgkDnhq5 Human: https://t.co/SXTsLBVYlN https://t.co/xMqBgxCPKh

March 13, 2021

Following 20 years of work on Mediator we share our human Mediator-PIC structure. Mediator hook reaches the TFIIH kinase active center. Great team @vasan06 @S_Schilb @shintoez. Note related work by @YuanHe_NWU @TjianDarzacq. Submitted version of Jan 25: https://t.co/SXTsLBVYlN https://t.co/vAdDSak4Nb

March 08, 2021

Our new paper suggests that co-transcriptional spliceosome assembly triggers efficient release of paused RNA polymerase II for active transcription. Great contribution of first authors @LCaizzi and @SaraMM_4 to #womansday2021! Paper: https://t.co/gEjvLpMN1g https://t.co/pwxMT4bs85

March 07, 2021

We began to collect our structural movies here. We will also upload more talks and other videos of interest. https://t.co/QIGDOK7bz0 via @YouTube

March 04, 2021

Nuclear condensation of NELF: Summary of our collaborative paper with the Sawarkar lab. @rawatravans @MarcBoehning https://t.co/28WZQ3NdFt

March 02, 2021

How chemotherapy works: Great advances in understanding cisplatin since we described in 2007 how this anticancer drug initiates DNA repair. https://t.co/8hgTDVJwrF

March 02, 2021

Registration is now open for the IGBMC-FMI Graduate Student Symposium taking place online April 26-29, 2021. Program includes Cell Biology, Structural Biology, Neurobiology and Epigenetics. @IGBMC @FMIscience @eucor https://t.co/0iOWORMN8q

February 28, 2021

Soon 750 million doses of #vaccine may be produced p.a. at the medieval town of Marburg where immunology pioneer Emil von Behring had used money from the 1901 Nobel Prize to fight diphtheria and tetanus. https://t.co/KZh1GQ7JU9

February 28, 2021

BioNTech founders receive the Order of Merit of the Federal Republic of Germany, many congratulations! https://t.co/3zChpbPs5a

February 26, 2021

Looking forward to speak about “RNA polymerases and #COVID19” at the award event @GBM_eV together with virologist @c_drosten from @ChariteBerlin on March 26. Registration: https://t.co/dpOAVhWoPC https://t.co/5vi5dZCL4S

February 24, 2021

@willida25 @CWolberger @WomenScienceRFS https://t.co/L35xbqDN7s

February 24, 2021

Very grateful to @ERC_Research for funding that also facilitated our work on the #coronavirus polymerase. Thanks to @CORDIS_EU for highlighting our results obtained together with @HoebartnerLab on antiviral drug effectiveness and #Remdesivir: https://t.co/ZVU7T3Ygbq https://t.co/xaGU6PtnkN

February 24, 2021

Looking forward to speak tomorrow at the International Young Scientists Conference on Molecular and Cell Biology organized by young scientists in Warsaw @IIMCB_Poland. Program: https://t.co/uBozI2Povv Website: https://t.co/FHt8UTMI3n https://t.co/njloAltBUE

February 23, 2021

After seven exciting years we have to say good-bye to @LucasFarnung. We thank him for all his great contributions @mpi_bpc and wish him all the best as starting assistant professor @HarvardCellBio @harvardmed. https://t.co/5DvKqYEwfH https://t.co/ruqKMDS1I8

February 22, 2021

Looking forward to speak at the Helmholtz Drug Discovery Conference 2021 that takes place on March 25-26. Free registration: https://t.co/esFK0Cn36Y https://t.co/zCUFNuThrb

February 21, 2021

@alena_buyx Ein großartiger Erfolg, der auf Jahrzehnten von Forschung beruht.

February 20, 2021

TT‐seq maps thousands of eRNA-producing enhancers in human cancer cell lines, providing ~40,000 putative enhancer-promoter pairs, many at cancer‐associated genes. https://t.co/u5n4HxNZE1

February 18, 2021

Great Harnack Lecture by @francesarnold yesterday on enzyme evolution, referring also to the founder of our institute, Manfred Eigen. @mpi_bpc @maxplanckpress https://t.co/x7gp5QVbVa

February 16, 2021

From our work with the Sawarkar lab we propose that stress-induced NELF condensates are nuclear counterparts of cytosolic stress granules. These two condensates may drive the coordinated downregulation of transcription and translation in cells. https://t.co/BF617f0the

February 13, 2021

Deutsche Zusammenfassung unserer Studien zur #Coronavirus Replikation und deren (unvollständige) Inhibition durch das #COVID19 Medikament #Remdesivir https://t.co/vfiwLYQGOk https://t.co/8EoFHgyeuP

February 13, 2021

In 1988, Paul Sigler suggested the CTD binds transcription activators: https://t.co/YmSt9zHSHk Now we see that CTD shortening delays transcription activation... https://t.co/tmRbQpftsc ...and this may be due to CTD-dependent Pol II clustering at genes: https://t.co/429nhCSFwZ https://t.co/aSbDWwfVy4

February 09, 2021

Deadline approaching: apply now to join our PhD program for Genome Science @IMPRS_GS https://t.co/pJXX0OarIp https://t.co/c6iy2ysuv8

February 08, 2021

Now online: Shortening the #CTD of Pol II impairs enhancer transcription and gene activation: https://t.co/tmRbQpftsc This supports a model that CTD is important for Pol II recruitment to active genes by condensation: https://t.co/429nhCSFwZ Grateful to @DarzacqClaire @XDarzacq https://t.co/iwZ7nUp2Kr

February 07, 2021

Wonderful documentary about the visit of star chansonnière Barbara at Göttingen in 1964 and its role in German-French reconciliation. Even if you do not speak German or French, you can feel the famous „Göttingen spirit“. https://t.co/vxdKxCHpkM

February 05, 2021

Nuclear condensation of transcription factor NELF drives downregulation of genes upon stress. Great collaboration of Marc Boehning @mpibpc with @rawatravans and Ritwick Sawarkar @mpi_ie @MRC_TU Now online: https://t.co/UT1q4ao1Hh https://t.co/tuqB7Pxr4f

February 04, 2021

Multi-particle #CryoEM refinement by @DTegunov applied to tomographic data from @Liang_Xue_ in Julia Mahamid's lab @embl enabled us to see an antibiotic bound to its ribosome target inside a bacterial cell. Great collaborative work now published: https://t.co/hdFIjIZD90 https://t.co/yXWeQNeVeF

February 02, 2021

Looking forward to start off the Non-coding Genome Course tomorrow at Institut Curie, Paris. https://t.co/X4RFkH9I0y https://t.co/c7igWtlK0L

February 01, 2021

@PavelTomancak @CEITEC_Brno Great, many congratulations, Pavel!

February 01, 2021

Very grateful to obtain the Hector Science Award. Made possible by many highly dedicated coworkers and the support by mentors, colleagues and collaborators! @mpi_bpc @maxplanckpress @uniGoettingen @GeneCenter_LMU @LMU_Muenchen https://t.co/sgeVvnFnNL https://t.co/G4QfpGjram

January 28, 2021

Congratulations @DTegunov for passing the PhD defense! Outstanding thesis describing Warp and M software for #CryoEM data processing. https://t.co/5vZzAcOFJe https://t.co/d3qCRmhQyi https://t.co/LU6Rs1IWB3

January 27, 2021

Welcome to Göttingen, Metin Tolan! https://t.co/SY877otpS3

January 26, 2021

It is a great honor to receive the Jeantet Prize 2021. Very grateful to past & present coworkers for their contributions over the last two decades. Hoping we can soon get vaccinated and celebrate. @maxplanckpress @mpibpc @LouisJeantetFDN @uniGoettingen https://t.co/vkodhGD284

January 19, 2021

Welcome to Göttingen, @SLorenzLab ! https://t.co/Xa3kP3AEt2

January 16, 2021

Great summary of our findings on the remdesivir mechanism by Prisca Straub from @BR24 @BR_Wissen (German). https://t.co/MMoUq90REj

January 15, 2021

Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters. Glad we could contribute to this work by @MYCGyvers https://t.co/36Ju1ArVq7

January 15, 2021

What does "co-transcriptional splicing" mean? Our model implies that spliceosome assembly is truly co-transcriptional, i.e. functionally dependent on active Pol II. The ensuing catalytic steps of splicing may be Pol II-independent, although they can occur on nascent RNA. https://t.co/PsLmKRGp2k

January 14, 2021

Pol II directly binds U1 snRNP: We propose a 'growing intron loop' model for co-transcriptional splicing. Great collaboration with R. Lührmann @mpi_bpc. Now online: https://t.co/jSxeoOxaQx https://t.co/agPksPLhUt

January 13, 2021

Here is the press release for our remdesivir paper, great collaboration with @HoebartnerLab: https://t.co/2npg4jLrBo https://t.co/oLXkt7cyQe

January 12, 2021

#Remdesivir does NOT block #coronavirus polymerase. It imparis RNA translocation and causes an elongation barrier that is overcome at high substrate concentrations. Our paper presenting the mechanism of remdesivir action is now online: https://t.co/vv2LjM4kjT #SARSCoV2 #COVID19 https://t.co/Y5OROcde0G

January 06, 2021

@Alexis_Verger Cest frai

January 04, 2021

We stand on the shoulders of giants: 50 years ago, visionary scientists agreed to collect all macromolecular structures in a database, the PDB, which also set standards for structure quality and formed the basis of numerous innovations in biomedicine, chapeau! https://t.co/bm4BjocNA1

January 01, 2021

Now published: Integrator is a genome-wide attenuator of non-productive transcription. Great collaboration with ⁦⁦@torbenheick⁩. Note conceptual similarity to yeast transcriptome surveillance by Nrd1: https://t.co/o3b8FGc7BN https://t.co/kEh7YgWOYY

December 31, 2020

As 2020 ends - many thanks to all coworkers, alumni, collaborators, colleagues and friends! https://t.co/0UqU2eUmdd

December 29, 2020

mRNA vaccine is an amazing success, based on basic molecular biology, incl.: -Discovery mRNA 1961 -Genetic code & translation -Codon optimization -Phage pol IVT -RNA modification & stability -Structure-based protein engineering 2017 https://t.co/81A4MD5wdK

December 16, 2020

Small-molecule inhibitors of human mitochondrial DNA transcription. Happy we could contribute to this great work by the labs of Claes Gustafsson & Nils-Göran Larsson! ⁦@mitopinionated⁩ ⁦@hauke_hillen⁩ https://t.co/M8Sa0herUe

December 11, 2020

Many congratulations to our colleague Asifa Akhtar for receiving the Leibniz Prize 2021! https://t.co/4AwxgeHGnk

December 10, 2020

Thanks to our secret santa @KJArmache for joining today‘s zoom Christmas party! https://t.co/ac1i29nzXx

December 07, 2020

Congratulations to Ruth Ley for obtaining the Otto Bayer Award 2020! Congratulations to Julia Mahamid, Josep Cornella, Nikolai Franzmeier and Marinka Zitnik for obtaining the Early Excellence in Science Awards 2020! @CornellaLab @nfranzme @marinkazitnik https://t.co/850w2NHMYT

December 03, 2020

SAVE THE DATE: Dec 7-11, 2020 Online Workshop "Mechanisms of gene transcription and its regulation" - emphasis on mechanisms and covering transcription systems from viruses to human. Much looking forward to meet close colleagues! Program: https://t.co/HamuepVnJD @LandickLab https://t.co/AiL1BAt1gg

December 02, 2020

The talk by Ayelet Shachar on ‚Shifting borders in the time of #COVID19‘ is now online. https://t.co/AnZhPP5ci0

December 01, 2020

Our new manuscript sugggests how Chd1 and FACT mediate Pol II transcription through a nucleosome. Pol II partially unwraps DNA, activates Chd1 translocase and recruits FACT histone chaperone. Masterpiece by @LucasFarnung with M. Ochmann, M. Engeholm. https://t.co/byUdnAUp0i https://t.co/QB2IxoxOYv

November 30, 2020

Today‘s nearly unbelievable breakthrough in structure prediction should help us obtain missing building blocks for large complexes. ‘It will change everything’: DeepMind’s AI makes gigantic leap in solving protein structures https://t.co/rT9gI8VoZN

November 22, 2020

@ABaerbock Wichtiger Schritt, sich der Gentechnik zu öffnen! Für Medizin, Ernährung und Umwelt.

November 20, 2020

Today we had to say good-bye to Anna (Ania) Sawicka who leaves to take a biotech job in Wroclaw and will be much missed. Stay tuned for Ania's forthcoming paper on the role of the CTD in transcription activation. https://t.co/xJVHG2RQnH

November 18, 2020

@AsifaAkhtar1 @nature Congratulations Asifa!

November 18, 2020

Looking forward to the CCP-EM symposium on the structural biology of #SARSCoV2 and methods development starting today. @ccp_em @EMDB_EMPIAR @wellcometrust https://t.co/5lXaJHycLt

November 12, 2020

@carninci @ewanbirney Great opportunity! Best of success!

November 09, 2020

@AndreaMusacchi1 @YouTube Many congratulations again, Andrea!

November 09, 2020

@JoergLab I must admit that I was hopeful but also skeptical. Let’s hope for the best.

November 07, 2020

A good day for the global scientific community. https://t.co/dbGWKwK8PX

November 07, 2020

@LenaRogl @KamalaHarris So great

November 07, 2020

@mbeisen So great

November 07, 2020

@ewanbirney @jcbarret So great

November 07, 2020

@ArndtLab @jengoefried So great

November 06, 2020

@markschies @HumboldtUni @bbaw_de @ECChronoi @degruyter_TRS Mein Gefühl ist: wir sehen nur noch chronos und kairos wurde vergessen. Dabei werden wir uns später nur an kairos erinnern.

November 06, 2020

Welcome to the new members of our Genome Science graduate program! Including Aiturgan @zhnbkv_ and Florian @FKabinger in our laboratory. https://t.co/ruT8JPdiIL

November 05, 2020

This year's Genome Science lecture series starts tomorrow, Friday at 4.15 pm. @IMPRS_GS https://t.co/8PJLvEou7f

November 01, 2020

As we enter a second (partial) lockdown tomorrow it is so good to know to have such talented, cooperative and resilient coworkers. https://t.co/7xHTJ0PJyl

October 31, 2020

Looking forward to speaking at MIT Biology Colloquium Series on Tuesday Nov 03 at 4 pm EST. Hosted by postdocs. @MITBiology @anafiszbein https://t.co/85eqPAEkTP https://t.co/WbuaLsSEFJ

October 30, 2020

Science communicator and influencer @maithi_nk on basic science @Literaturherbst Göttingen tonight. https://t.co/Ymhzw7V2Qu

October 29, 2020

Solving the remdesivir mechanism was possible in a great collaboration with @HoebartnerLab @Uni_WUE. They synthesized RNA with remdesivir at defined positions. We used their RNA to trap the remdesivir-stalled state of the #SARSCoV2 polymerase by #cryoEM. https://t.co/q7Fgblhm3m https://t.co/VZddeDKz2u

October 29, 2020

We show how the #COVID19 drug #remdesivir inhibits #coronavirus replication: Remdesivir stalls the viral polymerase by posing a translocation barrier, retaining the RNA 3'-end in the substrate-binding site, and hindering RNA proofreading. Preprint: https://t.co/q7Fgblhm3m https://t.co/exN3d51KYk

October 28, 2020

These events are now accessible with your "ON AIR" ticket: Ayelet Shachar: The shifting border (English) https://t.co/cTdIp468UT Jutta Allmendinger: Vertrauen (German) https://t.co/1RheWZyO3A Jörg Hacker: Pandemien (German) https://t.co/DPiYYV6dEN https://t.co/ikOwTP9Ymf

October 27, 2020

@mpi_bpc @maxplanckpress So great

October 26, 2020

@Karl_Lauterbach Danke für diese guten Worte. Eine schreckliche Nachricht und ein enormer Verlust auch für uns Göttinger.

October 24, 2020

@PlantEvolution I was also totally taken by it

October 23, 2020

Congratulations to Jutta Allmendinger for obtaining this year‘ science communications medal! https://t.co/X8E2roFqRR

October 22, 2020

Two simple steps to join the literature festival events. Some in English. Starting tomorrow Friday 7 pm with Jutta Allmendinger @JA_Allmendinger https://t.co/3uxFzUE3kD

October 22, 2020

This year’s lab retreat took place at home and featured great talks by @5_Baldi, @dhnisz, @bulutkarslioglu, Markus Wahl and Jan-Philipp Juncker. Great variety from structure to condensates to cell transitions. https://t.co/WHQbbwRHtj

October 20, 2020

Our RNA polymerase II-U1 snRNP structure elucidates co-transcriptional splicing. It suggest a nascent RNA loop on the Pol II surface enables efficient splice site scanning. Fabulous work by Suyang Zhang in collaboration with the Lührmann lab. Manuscript: https://t.co/jr9y6IbZUX https://t.co/eKHAUoEWsn

October 17, 2020

Some thoughts on where our research field may be heading. From a discussion at the Keystone Meeting on Gene Regulation earlier this year. https://t.co/uR6PpKeb9f https://t.co/24qnLHlVV5

October 17, 2020

She wants to encourage young people to become scientists: “It’s curiosity and passion!” - star photographer Herlinde Kölbl at the opening event of her exhibition ‘Fascination of science’ at Paulinerkirche Göttingen @Literaturherbst @mpi_bpc https://t.co/oK09zHZMRX

October 16, 2020

@Helmholtz_HZI @helmholtz_de Toll, dass das HZI Emmanuelle Charpentier nach Deutschland geholt hatte!

October 16, 2020

@SchindelinL @KiskerLab @RVZ_Wuerzburg @Uni_WUE Really great!

October 16, 2020

@JA_Allmendinger Es freut mich, dass sie jetzt auf Twitter sind aber noch mehr, dass Sie uns bald in Göttingen zum Literaturherbst besuchen!

October 14, 2020

Save the date and keep fingers crossed that we can meet in person. https://t.co/WtxZSnXdax

October 13, 2020

Looking forward to this workshop on the noncoding genome in Paris. https://t.co/zTYel3h0na https://t.co/TWZpMzVluu

October 12, 2020

@patrick_pausch Yes. Absolutely. But most EM structures rely on fitting prior X-ray structures still.

October 09, 2020

Our review containing all RNA polymerase II structures is now freely available online: https://t.co/qpBpD5K51u https://t.co/vEEgjB7Gjl

October 07, 2020

Remembering the Paul-Ehrlich-Prize 2016 to Emmanuelle and Jennifer with former lab member Claus Kuhn as junior awardee. @doudna_lab https://t.co/2PFd9yEXlp

October 07, 2020

And here comes the next generation: a very warm welcome to our new group leader at the institute, Marieke Oudelaar! Her group will study genome organization and regulation. @MariekeOudelaar Website: https://t.co/lfP1FwEQoD https://t.co/L8OXkq11qV

October 07, 2020

Many congratulations to our Max Planck colleague Emmanuelle Charpentier and Berkeley structural biologist Jennifer Doudna for the Nobel Prize 2020! So great! @doudna_lab @maxplanckpress https://t.co/hRB51WTFK1

October 06, 2020

Many congratulations to our Max Planck colleague Reinhard Genzel for obtaining the Nobel Prize in physics. Fabulous! https://t.co/WPjNRlYjpd

October 02, 2020

Very excited to meet legendary photographer Herlinde Kölbl in Berlin tonight. Her recent project ‚fascinating science’ features 60 scientists from around the globe. @bbaw_de https://t.co/6b1CBjq86v

October 01, 2020

Our new ‘Eigen Lounge’ is now ready for coffee and round table discussions. It commemorates the founder of our institute, Nobel laureate Manfred Eigen. https://t.co/fQlq1CPpUT

October 01, 2020

Hauke Hillen is starting as a tenure-track professor today at the University of Göttingen & UMG. Congratulations and all the best to the new lab! @hauke_hillen @uniGoettingen @mpi_bpc https://t.co/D0EE1Wjx1z

September 29, 2020

@TheresiaBauer @unikonstanz @maxplanckpress @martinwikelski Das freut mich als gebürtigen Schwaben besonders! Ich erinnere mich an die interessanten Diskussionen zur Gründung dieses großartigen Instituts. Einzigartige Technologie @martinwikelski

September 23, 2020

Great opportunity for ambitious junior researchers! Please do not hesitate to contact your favorite Max Planck Institute for advice. https://t.co/c90PeXKz62

September 20, 2020

@AmyShaubMaddox The loneliness of the leader

September 16, 2020

The literature festival @Literaturherbst is starting soon. Looking forward to host (7 pm): Jutta Allmendinger (sociology), October 23 Jörg Hacker (pandemics), October 25 Ayelet Shachar (borders & migration), October 27 One online ticket for all events: https://t.co/xcWzwpRIzD https://t.co/1PXiSQ7S9x

September 14, 2020

@AprilPawluk @MolecularCell @CellReports @CellPressNews Best of success! To best serve the community I recommend to take clear decisions.

September 13, 2020

@FuturiumD Viel Erfolg!

September 13, 2020

@SteffenKrach @ChariteBerlin Ja, ein großer Glücksfall für Berlin!

September 11, 2020

A 15-minute summary of the current state of our work on #SARSCoV2 polymerase and its inhibition by #remdesivir #COVID19 https://t.co/FrwM9QuiP7

September 11, 2020

Save the date: #COVID19 #SARSCoV2 Cold Spring Harbor Asia Virtual Conference on Nov 2-4, 2020. https://t.co/aEpT42BaP5

September 09, 2020

@KouMurayama @uni_tue @AvHStiftung Welcome

September 08, 2020

Now published: our method detecting newly synthesized RNA isoforms and monitoring isoform metabolism in cells (nano-ID). Great team effort coordinated by Björn Schwalb @birdumbrella. #nanopore @nanopore @NanoporePapers Paper: https://t.co/zvdKCZ2zQz https://t.co/DRbE3sqx1p

September 07, 2020

@maithi_nk Many congratulations!

September 03, 2020

Many congratulations to our colleagues at the institute, Juliane and Stefan! https://t.co/W0KiCVJUmW

August 28, 2020

@KellyTHD_Nguyen This is so sad, Chris had organized a great party on the occasion of Kiyoshi’s 70th birthday last year which had to be canceled due to his illness...this is so sad.

August 27, 2020

@Pol2Runner Yes in the nucleosome

August 27, 2020

Half a year later: first real space Cramer lab group meeting with distancing. https://t.co/eI9GImYK2y

August 26, 2020

Looking forward to this student-organized symposium on October 7-8, 2020. #Eureka2020 https://t.co/lkBk6PAR1B

August 24, 2020

Join the 17th Horizons in Molecular Biology Conference on September 14-17, 2020! Great speaker line-up. https://t.co/fVyS04OcSW https://t.co/s51xWYCMal

August 22, 2020

Here we review all ~200 available Pol II complex structures and summarize how these elucidated transcription initiation, promoter-proximal pausing and elongation, and the navigation of nucleosomes and DNA lesions. https://t.co/YkGP5BZeWP

August 20, 2020

Free download of the benchmark paper on Rosalind Franklin and the advent of molecular biology: https://t.co/2ojECGGsLl #franklin100 #WomenInStem #DNA https://t.co/nAqRYMTkT7

August 19, 2020

Save the date: The 86th Harden Conference - Machines on Genes is rescheduled for 9-13 May 2021 and takes place in Alicante, Spain. https://t.co/VQJdUkXCMS https://t.co/LvpMKR9AuO

August 19, 2020

Registration is now open for our local coronavirus research webinar symposium on September 3, 2020: https://t.co/PIhVyMF6nP https://t.co/9l3pjDW9vr

August 17, 2020

Defining permissive epigenomes that enable cell reprogramming by various transcriptional regulators. Happy we could contribute to this study by the Schöler lab. #stemcells https://t.co/ddBRdoD3GW

August 06, 2020

The final version of our paper reporting the #SARSCoV2 polymerase-RNA structure is now available. A basis for investigating #coronavirus replication-blocking antivirals such as #Remdesivir. https://t.co/vYBLxdAiik https://t.co/c8Q7oyhtBG

August 02, 2020

Integrator is a genome-wide attenuator of non-productive transcription. Combining factor depletion, TT-seq and bioinformatics. Great collaboration with @torbenheick. Manuscript: https://t.co/3Zxz8SFRti https://t.co/1UjkZLyNtk

July 30, 2020

Now online: visualizing the central dogma inside cells! Glad we could contribute to this marvelous work on the expressome by the labs of Julia Mahamid and Juri Rappsilber @RappsilberLab @FJ_OReilly @Liang_Xue_ @DTegunov @JorgStulke @embl Paper: https://t.co/ti5akkIEFI https://t.co/Y8XhaWJF1S

July 30, 2020

Thanks to the editors at Cell for prioritizing this important historical topic. #Franklin100 https://t.co/suFR9x56CR

July 30, 2020

@CWolberger Thank you for your great thread on this topic, Cynthia!

July 29, 2020

@g1_guillermo @cryoEM_Papers @MolecularCell @CRISPR_News @sofos112 @SQunxin @NNFCPR @UCPH_health Really great, many congratulations!

July 29, 2020

Rosalind Franklin provided the key data for deriving the double helix structure of DNA. She also pioneered studies of viruses and RNA. This benchmark essay celebrates the 100th anniversary of Franklin’s birth and the advent of molecular biology. https://t.co/reVcNSRyer

July 28, 2020

Join the seminars by Lucas Farnung and Hitoshi Kurumizaka tomorrow. https://t.co/zHPDjAMgj5

July 26, 2020

@CWolberger I agree; there will be a paper on this in Cell on Wednesday.

July 24, 2020

@giacomo_cavalli Thanks Giacomo; there will be a paper in Cell on her next week. Best

July 22, 2020

@TriggerLoop @researchsquare Maybe a biogenesis/assembly factor?

July 22, 2020

@afisch82 @TriggerLoop @JosefowiczLab @sjosefowicz Really great, many congratulations!

July 17, 2020

Patrick‘s overview seminar given at Dana Farber/Harvard Cancer Center is now available online: https://t.co/wqEM1kibS0 https://t.co/46mOKTdnEW

July 14, 2020

Join Patrick’s talk online at Dana Farber/Harvard Cancer Center @df_hcc on Thursday at 12 noon Boston time. https://t.co/ReuMwII1dH https://t.co/DBQJVaRrs1

July 03, 2020

Dimitry Tegunov‘s multiparticle cryo-EM refinement software ‚M’ is now available for download. https://t.co/c72Qsg9QXZ

July 01, 2020

Very much looking forward to work with our new leadership! @AsifaAkhtar1 https://t.co/oR7eNm5n8F

June 17, 2020

Evidence that CDK12 maintains an active transcription elongation complex by retaining the PAF complex. Happy we could collaborate with the lab of Shona Murphy. https://t.co/2RA2kAfIpc

June 16, 2020

@STOPlabPl Good luck!

June 16, 2020

Our new paper on the nucleosome-CHD4 chromatin remodeler structure is online. CHD4 is involved in gene repression and does not detach terminal DNA, in contrast to Chd1, which works in active transcription. We also map disease mutations. @LucasFarnung https://t.co/uxpEJQyEPv https://t.co/BsU9J4SV1c

June 16, 2020

Save the dates: program for our next seminar series is out. Much looking forward to host our colleagues @Beck_Laboratory, @HymanLab, @KukulskiWanda, Edward Lemke, Frank Uhlmann, @NVastenhouw & @tinekelenstra. https://t.co/fnNOq392Nu https://t.co/RTnryRTsza

June 16, 2020

Like other enzymes, Pol II is regulated allosterically by proteins that influence active site structure & dynamics from a distance. First seen for the initiation factor TFIIB, now for the elongation factor RTF1. TFIIB: https://t.co/NksFDlWsqN RTF1: https://t.co/rAXISgAZ7O https://t.co/Z7FhNnZeNy

June 15, 2020

Pol II speed is enhanced by PAF subunit RTF1. Our new paper shows allosteric activation via the famous bridge helix. @seyvos @LucasFarnung Publication: https://t.co/L8D6mYZr6N

June 10, 2020

@billhansson @maxplanckpress Thank you so much for everything, Bill!

June 09, 2020

Isaac Fianu passed his PhD defense today, many congratulations! https://t.co/GOt5WtSvH7

June 08, 2020

CTCF-dependent genome topology is not strictly required for a functional cell-fate conversion but facilitates a rapid and efficient response to an external stimulus. Happy we could contribute to this important study of the Graf lab @CRGenomica. https://t.co/tqfqhj8HoB

June 06, 2020

@brodriguezsci Best to ask Dimitry...

June 06, 2020

"In agreement with a model of condensate-driven transcription initiation, large clusters of hypophosphorylated Pol II rapidly disassembled upon Mediator degradation." Happy we could contribute to this great collaboration with Martin Jaeger and Georg Winter. https://t.co/9hk3s9CNhW

June 06, 2020

Dimitry Tegunov's software 'M' enables multi-particle refinement and higher resolution in #cryoEM. Applied to tomography data from @Liang_Xue_ & Julia Mahamid @embl, M reveals ribosome-antibiotic complex at 3.7 Å in cells. @DTegunov @c_dienemann Preprint https://t.co/d3qCRmzrWS https://t.co/4SjBSY4rbW

May 26, 2020

We welcome our new colleague at the institute, Claus Ropers! https://t.co/4YEpnHnEs9

May 26, 2020

Welcome at our institute, Stefan! https://t.co/vNyK7kZJK0

May 25, 2020

Happy to join and serve on the Scientific Advisory Board of the Gulbenkian Institute in Lisbon, Portugal. https://t.co/0hyK0SEeQF

May 21, 2020

Our paper describing the #coronavirus RNA polymerase structure is online. The nsp8 extensions contact RNA far away from the active site, apparently enabling processive replication of the very long #SARSCoV2 genome. Publication: https://t.co/go28YxOvaO PR: https://t.co/bT7ig1Oyjc https://t.co/9qHUsPvDru

May 18, 2020

After nearly two months in home office we carefully return to the lab. Here are 56 thoughts of the day that accumulated: https://t.co/HasfvfbCp3 https://t.co/5GCJzBFcoD

May 16, 2020

@IbrahimCisse_ @MIT_Physics @Cisse_lab Great many congratulations

May 15, 2020

Happy to share the original cryoEM data used to solve our #coronavirus #SARSCoV2 polymerase-RNA complex structure. https://t.co/NF2RBnWS4P

May 13, 2020

Explore #coronavirus replication in 3D. Our structural data for the RNA-dependent RNA polymerase of #SARSCoV2 in replication mode are now online: PDB: https://t.co/A1NQ6HZTDE EMDB: https://t.co/ccvuMIKC9R Preprint: https://t.co/KWD2bgPWGb PR: https://t.co/bT7ig1Oyjc https://t.co/eKazemLzog

May 08, 2020

@Alexis_Verger @MED_COMPLEX Hey very nice overview! Is it really already two decades? Well yes we got older...

May 06, 2020

@lkreidberg Welcome and all the best! Patrick Cramer

April 30, 2020

Here is a simple animation of #coronavirus replication: NTPs enter from the right and are added to the growing RNA copy (red) of the #SARSCoV2 RNA genome (blue) by the viral polymerase. #COVID19 Preprint: https://t.co/KWD2bgPWGb Press release: https://t.co/bT7ig1Oyjc https://t.co/2n7roSm6MS

April 28, 2020

Watching #coronavirus replication! #SARSCoV2 polymerase-RNA structure: basis to study potential #COVID19 drug #Remdesivir Team @hauke_hillen @KokicGoran @LucasFarnung @c_dienemann @DTegunov @mpi_bpc @maxplanckpress Preprint https://t.co/KWD2bgPWGb PR https://t.co/bT7ig1Oyjc https://t.co/sNHHRcx7qe

April 27, 2020

Very honored to be elected as a foreign member of the National Academy @theNASciences. Many thanks to my colleagues and friends in the US! https://t.co/cXTwLGufDp https://t.co/CsWJaQhAyu

April 22, 2020

Our structures of nucleosome-bound Yamanaka factor Sox2 and Sox11 elucidate how pioneer factors invade chromatin for differentiation and development. https://t.co/ypkUInxsGu https://t.co/m21gRRsUxB

April 20, 2020

Many congratulations to Lucas Farnung who accepted an offer from @Harvard and will start his lab at Boston in January 2021! https://t.co/fLpQaTbISo

April 18, 2020

@EsbinMeagan Many thanks indeed, really very kind of you! Please send my regards to Tij!

April 17, 2020

25 days in home office started with 25 thoughts of the day. Here they are: https://t.co/cdqvRFsNR2 https://t.co/SxCJ4MkxPk

April 17, 2020

@FMIscience @SchubelerLab Congratulations and best wishes, Dirk!

April 01, 2020

Increasing the sensitivity of crosslinking-mass spectrometry with a new peptide database. Glad we could contribute to this important technical development of the lab of Henning Urlaub. Publication: https://t.co/agjmRzlTxi https://t.co/zi96Zj4T3H

March 31, 2020

We are supported again by an Advanced Grant of the European Research Council @ERC_Research. With these funds we will extend our research towards the mechanisms of chromatin transcription. Thanks to all coworkers who made this possible. https://t.co/JuPRL0gqg4 https://t.co/kuCHrWV8Mm

March 25, 2020

We start each day in home office with an encouraging philosophic quote in our Email inbox. Here is today's: “What does not engage our feelings does not long engage our thoughts either.” Lou Andreas-Salomé, Russian-German author 1861 St. Petersburg – 1937 Göttingen https://t.co/uBU8Og62We

March 23, 2020

First virtual Cramer lab meeting. Science continues mainly online. Take care of yourselves during these times. https://t.co/pkSSFdaLHT

March 11, 2020

Our structure of the SWI/SNF chromatin remodelling complex RSC is now published! https://t.co/i1cGE7b8Cr

March 08, 2020

Great event this weekend @uniGoettingen @thegoecampus @ForumWissenGoe celebrating the international women's day #IWD2020 featuring Margot Kaessmann, Naima Diesner, Nivedita Mani, Jacqueline Amirfallah, Katrin Adt. https://t.co/tRYnNTHkjA

March 01, 2020

Chromatin remodelers contain ‘ruler’ elements that set nucleosome array spacing. Happy we could contribute to this collaboration between the labs of Philipp Korber, @hopfnerlab and @PetersonLab. Preprint: https://t.co/H770mZdp2O

March 01, 2020

The expressome structure we obtained in 2017 in vitro after stalling RNA polymerase (collaboration with Landick lab) is now shown to be adopted in vivo as an inactive state when transcription is blocked. Link to our 2017 in vitro expressome paper: https://t.co/GOAUCJtws1 https://t.co/zaWPQZkdqB

February 29, 2020

Visualizing the central dogma in cells! The labs of Julia Mahamid @embl and @RappsilberLab present the in situ structure of the transcribing-translating expressome. Glad we could contribute. @DTegunov @WimJHH @JorgStulke Preprint: https://t.co/o2LQ8OGccr https://t.co/zhY9PEyaM1

February 28, 2020

@FRobertLab @JeronimoCelia Absolutely great

February 27, 2020

Register for the "Gene transcription in yeast” Conference that takes place June 13-18, 2020 in Sant Feliu de Guixols, Spain: https://t.co/afkBJuTlfd https://t.co/03KRZN3WlL

February 26, 2020

Welcome to our new colleage Jochen Rink! @rinklab @mpi_bpc https://t.co/j25SijXy2c

February 26, 2020

Today we celebrated our recent successes with a lunch at a nearby village! Nice walk passing two medieval churches... https://t.co/A9Fs6bhqB2

February 13, 2020

Save the date: @ASBMB Meeting on Transcriptional Regulation: Chromatin and RNA Polymerase II takes place Oct 1-5, 2020 in Snowbird, Utah. https://t.co/SSzLLWTDHy https://t.co/GVgwjyBTS3

February 10, 2020

It is an honor to accept the Otto Warburg Medal on behalf of past and present members of the laboratory. The Warburg Lecture will take place on April 3, 2020 during the GBM symposium on “The world of RNAs” https://t.co/aedOREHqqj https://t.co/IzP4TKopSw https://t.co/RZvzPxiweV

February 05, 2020

Shintaro Aibara obtained a Marie Curie Fellowship of the European Union, many congratulations! https://t.co/PB18hXFqhW

January 28, 2020

The Hilldale Lecture given by Patrick at the University of Wisconsin in Madison last week is now available at YouTube: https://t.co/ofQMzPXRZd @UWBiochem https://t.co/UScwPXP9vf

January 27, 2020

Around 450 participants at the joint Keystone meetings on Gene Regulation and Cancer Epigenetics! Follow us: #KSgene https://t.co/BJMR67L7Vr

January 22, 2020

Our structure of the chromatin-modifying coactivator SAGA elucidates early events before transcription pre-initiation complex formation. Note related work from the Schultz lab published back-to-back. @mpibpc @igbmc https://t.co/iCx29FDwyt https://t.co/XoPYpknrPo

January 14, 2020

Patrick Cramer will give the Weisbach Memorial Lecture @RockefellerUniv this Friday at 4 pm https://t.co/CKQi3BCEN1 https://t.co/FHrag0tOKU

January 06, 2020

Save the date for the key European transcription/chromatin conference of the year, taking place 29 August to 01 September in Heidelberg. And: Happy New Year from the Cramer lab! https://t.co/Zep9E7ltWj

January 04, 2020

@Lab_Journal Was sind die neuen Forschungsfelder in den Life Sciences, die in Deutschland zu wenig präsent sind?

December 19, 2019

Special Christmas reading on the efforts, rewards and drawbacks of exploration: 500 years after the first circumnavigation of the world... https://t.co/qZmNgI4Jf2 https://t.co/5yz0TBRrff

December 18, 2019

This video explains our work - with a focus on cryo-electron microscopy (English subtitles). Thanks to the Schering Foundation for enabling this. https://t.co/fiYY4A6FV8

December 17, 2019

Join the symposium to celebrate the 25th anniversary of the Eppendorf Award on June 25, 2020 in Heidelberg. Free registration: https://t.co/LmO3TpYQtc

December 12, 2019

First structures of viral multisubunit RNA polymerase: complete, core, transcribing, & capping complexes of Vaccinia show how such viruses make capped mRNA. Great collaboration with the lab of Utz Fischer in Würzburg! Free download: https://t.co/jTAj7hJp8n https://t.co/u3i6i8ERQf https://t.co/69NlmGgC65

December 09, 2019

Recognition of histone H3 trimethylated at K36 by a conserved reader domain: Our new paper reports the structure of the modified nucleosome-PWWP complex and multivalent binding to the methylated histone tail and both DNA gyres. @NatureSMB https://t.co/yGZ3jYcMKU https://t.co/ixqyTC5KWP

December 08, 2019

Our colleague Reinhard Jahn startet as new president of the University of Göttingen. Hear his inauguration speech (in German): https://t.co/4Xdfu5ylvC

December 06, 2019

Hosting Hans Schöler as our Christmas Speaker 2019! https://t.co/5WfSr9BVub

November 29, 2019

Felix Wagner passed his PhD defense today, many congratulations! Cryo-EM structure of the SWI/SNF chromatin remodelling complex RSC bound to a nucleosome. https://t.co/BiIfxZV1aF https://t.co/TRVDPGCbbU

November 20, 2019

Marc Böhning passed his PhD defense, many congratulations! Pol II clustering driven by CTD phase separation. Great collaboration with @mz_science and @TjianDarzacq https://t.co/429nhCSFwZ https://t.co/S65GyGXAH2

November 05, 2019

Free download of the historic perspective on 50 years of eukaryotic transcription research. Summarizes major advances in the field and provides exemplary and key original references. https://t.co/EFGQ2KNTZK

October 28, 2019

Congratulations to Edith Heard, Director General of EMBL, who received the Hansen Family Award today for her pioneering work in epigenetics. @Bayer @emblebi @embl @heard_lab https://t.co/gS3hX54VJZ

October 22, 2019

The first scientific travel report: discussing Georg Forster‘s ‚voyage around the world‘ from 1777 with historian Frank Vorpahl @ZDF @Literaturherbst @thegoecampus @ForumWissenGoe https://t.co/bqwj2qEhqk

October 20, 2019

Rewriting human history: Our Max Planck colleague Johannes Krause explains how DNA sequencing revolutionizes anthropology. „We are all migrants!“ Today at @Literaturherbst @mpi_bpc @thegoecampus https://t.co/4f62RvbyfI

October 19, 2019

Amazing start of our public science talks at the literature festival 2019, from now on every evening for the next ten days. https://t.co/h1PqssJY3P https://t.co/HhpeNSmQha

October 15, 2019

Our structure of the SWI/SNF chromatin remodeling complex RSC bound to a nucleosome and exit DNA provides insights into formation of nucleosome-depleted, transcriptionally active promoters: https://t.co/BiIfxZV1aF Note forthcoming related work by @Nogaleslab and Yuan He's lab https://t.co/ROjnTE5EDi

October 14, 2019

Abstract deadline approaching for @KeystoneSymp meeting "Gene Regulation: From Mechanisms to Disease" in #Keystone. https://t.co/1Qfx1uzwsq. #KSgene https://t.co/yImAgztJn3

October 14, 2019

This month‘s issue of @Lab_Journal features a ‚journal club’ commentary on our work on how Pol II pausing influences transcription initiation. https://t.co/bUlirm1JDs https://t.co/sfMoqGKTot

October 13, 2019

Patrick will give lectures in Rotterdam, Utrecht, and Eindhoven on the next three days. Thanks to the Netherlands Society for Biochemistry and Molecular Biology for the invitation! https://t.co/3wUNKxu6NN https://t.co/emIPAsrKmY

October 09, 2019

Sunny Liu defended her PhD thesis, many congratulations! https://t.co/61wURpBvJ9

October 07, 2019

Now published: Real-time cryo-EM data pre-processing with Warp, by Dimitry @DTegunov. Warp corrects and denoises images, automatically picks particles, and generates output for RELION. @cryoEM_Papers #CryoEM Paper: https://t.co/5vZzAcx4RG Software: https://t.co/f6Zv2EDFl0 https://t.co/3tnVt8ctIF

October 04, 2019

Vasan Rengachari received a postdoctoral fellowship of the Engelhorn Foundation, many congratulations and best of success! https://t.co/6NIdf7c0Q8

October 01, 2019

A growing global network! Cramer lab reunion with diverse talks by alumni, full of advice: “Stay excited”, “follow your dreams”, “bring empathy to the table!” Thank you for sharing your experiences. @KJArmache @VanniniLab https://t.co/WnEguvYS0j

October 01, 2019

Congratulations to alumnus Alessandro Vannini, now Director of Structural Biology at Human Technopole in Milano! https://t.co/VXrnTkM3B2

September 30, 2019

Kiyoshi Nagai was a wonderful colleague, always interested in the latest science, always positive, and following an important long-term goal, which he achieved only recently; he will be sadly missed. https://t.co/m04d19DCPD

September 30, 2019

This year‘s lab retreat at Ringberg Castle starts off with a great talk by Julia Mahamid @embl https://t.co/9Hgj3mw9Ri

September 27, 2019

Many thanks to the Schering Foundation for organizing a great event in Berlin to celebrate the Ernst Schering Prize 2019. Thanks to all past and current members of the laboratory for their outstanding contributions that made this possible! @ScheringStiftg @mpi_bpc @thegoecampus https://t.co/RfUvvkAoPS

September 26, 2019

Today, Lucas Farnung received the Karl Lohmann Prize for his PhD research. He solved the first high-resolution structure of a complete chromatin remodeller, Chd1, bound to a nucleosome! https://t.co/ysa2ees7tR @mpi_bpc @LucasFarnung @thegoecampus @goetageblatt https://t.co/25TZmFCjkr

September 26, 2019

Thank you and all the best for the future! President of the University of Göttingen Ulrike Beisiegel is stepping down. @uniGoettingen @thegoecampus @mpi_bpc https://t.co/H95s2QXeBX

September 20, 2019

Apply and join the Max Planck Society as a Research Group Leader, great start-up packages offered! https://t.co/3fnaUX4Tex

September 11, 2019

Exciting line-up of speakers at the EMBO|EMBL Symposium ‘Multiomics to Mechanism’. Follow us at #eesomics https://t.co/RlKZ0JMCA7 https://t.co/tAFHFvYamJ

September 02, 2019

The Schering Prize 2019 recognizes past and current members of our laboratory and their fabulous research! Thanks also to everyone who supported us. Video (German): https://t.co/pjlfvtKcYy Press release (English): https://t.co/wrQot0EGcM https://t.co/cWTu9x06aM

September 02, 2019

Reunion with alumni Karim-Jean Armache (NYU), Alan Cheung (UCL), Andreas Mayer (MPI Berlin) and Seychelle Vos (MIT) at Cold Spring Harbor during #MOET2019. https://t.co/DIPZa4eu3p

August 31, 2019

Many thanks to all participants for the great positive energy at the CSHL anniversary transcription meeting #MOET2019 and for all contributions! Please save the date for the next meeting: Aug 31-Sep 04, 2021! https://t.co/bBd8wzqFiN

August 28, 2019

Now online: this review summarizes the state of the eukaryotic transcription field and describes the dynamic interplay between nuclear condensates and Pol II complexes that together organize transcription. #moet2019 https://t.co/sKh35wZuhk

August 28, 2019

Magnificent opening lecture by Bob Roeder, founding father of the eukaryotic transcription field, summarizes five decades of frontier research. #moet2019 https://t.co/nlGpP1HN0E

August 27, 2019

Celebrating 50 years of eukaryotic RNA polymerases at the Cold Spring Harbor meeting on Mechanisms of Eukaryotic Transcription, starting tonight. Follow us at #moet2019 https://t.co/Yo71UzoI3S

August 22, 2019

Last chance to register for this year‘s Horizons conference, organized by PhD students at our institute, great speakers! https://t.co/14FEG6hpCN

August 20, 2019

The exciting program for this year's literature festival is out. Covering politics, fiction, society, science, history. Mainly in German. Tickets are sold out quickly... Popular science talks: https://t.co/h1PqssJY3P Full program: https://t.co/leomP0xtnQ https://t.co/33QvnU0vVX

August 09, 2019

We show directly that transcription activation often involves a decrease in Pol II pause duration. Multiomics reveals this requires CDK9 and increases the productive initiation frequency. In contrast to promoters, enhancers are generally not pause-limited. https://t.co/RcJGLGHTTC https://t.co/cZRrlCZXo0

July 26, 2019

Saying thank you and good-bye to Seychelle Vos and wishing her all the best as Assistant Professor at MIT! https://t.co/lCG39hqhWP

July 17, 2019

Our new paper with the Sandberg lab describes NASC-seq, which monitors RNA synthesis (rather than RNA levels) in single cells and can be used to follow differentiation events. Publication: https://t.co/sSAj4entmH Protocol: https://t.co/KgiKn46ksM https://t.co/woeCL8rgfG

July 16, 2019

Sara Osman passed her PhD defense today, many congratulations! https://t.co/lJuxu5me0m

July 12, 2019

Katharina, Saskia and Goran formally graduated today, congratulations and all the best for the future! https://t.co/OqSlCMgDr4

July 08, 2019

We welcome our new colleague Ruben Fernandez Busnadiego, a master in cryo-electron tomography, at the Göttingen science campus! @uniGoettingen @thegoecampus @mpi_bpc https://t.co/BUakap2wEJ

June 30, 2019

Our structure of the human TFIIH-XPA-DNA complex is published. The results explain how TFIIH switches from a transcription factor to a DNA repair factor, and represent the first step in a mechanistic analysis of nucleotide excision repair. https://t.co/nsfd62mCGK https://t.co/CFzBZ6AZkj

June 26, 2019

Today Sandra Schilbach received the Otto Hahn Medal for her great work on solving the structure of the Pol II pre-initiation complex with TFIIH and core Mediator. Great location in Hamburg. Congratulations! https://t.co/B4rXsJF2h1

June 25, 2019

Our structure of the human chromatin remodeller CHD4 in complex with the nucleosome deviates from the previous Chd1 structure, consistent with a role of this factor in gene repression rather than active transcription. Manuscript: https://t.co/32xVF45gYT https://t.co/gpqYJdZyBr

June 24, 2019

Our new seminar program is out. Looking forward to host again fine colleagues at Göttingen. Save the dates! https://t.co/eAHFEwCcoi

June 13, 2019

TT-seq is widely applicable to monitor RNA synthesis and enhancer dynamics in human cells. We now provide a detailed lab protocol and bioinformatic analysis pipeline: Experimental: https://t.co/V4wa1tUkIf Analysis: https://t.co/GNsCK42lyG https://t.co/XHgxmczCY4

June 12, 2019

@NogalesLab @EMBO Great many congratulations

June 07, 2019

Our paper on splicing kinetics is out. In a collaboration with the @gagneurlab we provide rates for 5‘ and 3‘ RNA cleavage in human cells. https://t.co/klYpq9BdCu

June 01, 2019

Our structure of the super elongation complex (SEC) subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization in SEC formation. SEC functions in release of Pol II from promoter-proximal pausing. Manuscript: https://t.co/jLb9uZRsZ7 https://t.co/qA6F0XlmAJ

May 28, 2019

Our new paper presents transcriptome maps of 30 general RNA degradation factors, revealing their occupancy and possibly functional relationships. Great collaboration with the lab of Johannes Soeding! Manuscript: https://t.co/BhZb4H7FUE https://t.co/4UXDbg4q8k

May 24, 2019

Many congratulations to our colleague Brenda Schulman who received the Jung Prize for Medicine yesterday in Hamburg! https://t.co/MYJTGaEPQR

May 07, 2019

Our high-resolution structure of human TFIIH with DNA & XPA represents an intermediate of DNA nucleotide excision repair (NER). Watch how the transcription factor (@NogalesLab) switches to repair mode, engaging DNA with both ATPases, XPB & XPD. Manuscript: https://t.co/aWsVlPn8Zj https://t.co/A6xHe6zsQe

May 07, 2019

Many congratulations to our very successful postdoc Seychelle Vos who will open her lab at MIT this fall! https://t.co/5hnRrWVi9i

May 06, 2019

Congratulations to Katharina Hofmann and Saskia Gressel who both passed their PhD defense today! Great talks on functional genomics. All the best for the future! https://t.co/YQ4Mkf2u3e

April 27, 2019

@LugerLab @NatureSMB Really great many congratulations!

April 26, 2019

Our new paper elucidates human splicing kinetics. TT-seq and modeling reveal how splicing rates depend on Pol II elongation and RNA sequences. Great collaboration with Gagneur lab! https://t.co/kxrVJyATpX @eLife @RNASociety @RNApreprints @RNA_seq @gagneurlab @LCaizzi @leonhard https://t.co/f4tFR79Pkw

April 23, 2019

Save the date: Keystone meeting on "Gene Regulation: From Mechanisms to Disease" and a parallel meeting on Cancer Epigenetics take place January 26-30, 2020 in Keystone, Colorado. Please RT! Flyer: https://t.co/uFaseSDQYv Information: https://t.co/YRxQcU4xpM https://t.co/AXmEhCPGe9

April 10, 2019

Goran Kokic passed his PhD exam. Impressive work on TFIIH in DNA repair. Many congratulations! https://t.co/pIHWN40TQB

April 08, 2019

We report a method to directly sequence newly synthesized, individual mRNA transcripts in human cells. Reveals metabolism of RNA splice variants/isoforms. https://t.co/caANJDnPRg https://t.co/P3uYAy1QeR

April 04, 2019

The new childcare facility at our institute just opened. Many thanks to all who helped! https://t.co/ZVQKghN5fs

March 27, 2019

MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. Thanks to Elmar Wolf for the great collaboration. https://t.co/OeCE59w9jL https://t.co/cyPsNu5WuG

March 26, 2019

Fine collaboration with the Anikin lab now resulted in our paper on posttranscriptional gene regulation in mitochondria: https://t.co/VIGtGodbD2 https://t.co/WNqHaJKM29

March 26, 2019

Please RT: Cold Spring Harbor Meeting on Mechanisms of Eukaryotic Transcription takes place August 27-31, 2019. Celebrating 50 years of eukaryotic RNA polymerases! https://t.co/y4DQ8j6bhX https://t.co/CxbH0UP3aL

March 26, 2019

Save the date: EMBO | EMBL Symposium: Multiomics to Mechanisms - Challenges in Data Integration, 11-13 September 2019 at Heidelberg. https://t.co/RlKZ0Jv1bx https://t.co/wS545u4gMo

March 11, 2019

Deadline approaching for applications to become a Group Leader in our Lise Meitner program for young female researchers! https://t.co/ny8QUtavkO

March 05, 2019

We thank Randy Schekman for his outstanding service as first editor-in-chief of eLife and look forward to working with Michael Eisen to support the leading OA journal! https://t.co/rddwwVPUte

February 27, 2019

@UhlenhautLab Great, congratulations!

February 26, 2019

Congratulations to our friends at @BIMSB_MDC @MDC_Berlin on the opening of their beautiful new building in Berlin by chancellor Merkel today! https://t.co/YTUbpv5kc8

February 21, 2019

Save the date: conference on chromatin dynamics in Bad Nauheim near Frankfurt, September 9-11, 2019 https://t.co/ZzCpesQAP1

February 21, 2019

Many congratulations to our close colleague Herbert Jäckle! https://t.co/FymBSQ0EDY

December 27, 2018

Great collaboration with the Heard lab. TT-seq monitors X chromosome gene inactivation. Glad we could contribute to this interesting multiomics temporal analysis. @heard_lab https://t.co/yRR7xBxbge

December 22, 2018

Our structure of the transcribing RNA polymerase II-nucleosome complex is now published and available online https://t.co/nF7c1P1eWo https://t.co/qCWs4c3O5t

December 18, 2018

NASC-seq monitors gene activity in single cells by detecting new mRNA. Great collaboration with the Sandberg lab. Manuscript: https://t.co/q8r4EjQq7G https://t.co/Msaldzs5RM

December 14, 2018

@Beck_Laboratory Great to have you as a colleague! All the best

December 14, 2018

Hosting Asifa Akhtar from @mpi_ie as our Christmas speaker https://t.co/779umFJtuw

December 11, 2018

Suyang Zhang arrived from Cambridge @MRC_LMB and obtained an EMBO postdoctoral fellowship, many congratulations! https://t.co/Hkn3S4aJpd

December 06, 2018

And another Leibnizprize for our colleague Ayelet Shachar at the neighboring Max Planck institute, many congratulations! https://t.co/T32Mn9oeC3

December 06, 2018

Many congratulations to our colleague at the institute, Melina Schuh, for being awarded the Leibnizpreis, the highest distinction in Germany! https://t.co/SnsDMM0xIf

November 30, 2018

CPF and APT are required to form 3'-ends on coding and non-coding genes, respectively. Our paper resulting from a collaboration with @lapassmore is now online. https://t.co/tQ0ib7ol0f https://t.co/jPNlPzdI9u

November 21, 2018

We mourn the passing of Aaron Klug, a giant of molecular biology, who reported the first structure of tRNA https://t.co/otyrCARGcM

November 21, 2018

Our new structure suggests that DNA opening during transcription initiation involves promoter DNA distortion and closure of the RNA polymerase II clamp https://t.co/Z4brj4UezP https://t.co/49aFKPx3CN

November 20, 2018

Congratulations to former lab member Alan Cheung on becoming an EMBO Young Investigator! https://t.co/pxaF4oywJq

November 14, 2018

Save September 11-13, 2019, for the EMBO|EMBL symposium on ‚Multiomics to mechanism - challenges in data integration‘ https://t.co/syNTFveOq3 https://t.co/39VdY6zKDx

November 08, 2018

Many congratulations to Laleh Haghverdi and Julijana Gjorgjieva for receiving the Engelhorn Research Prize 2018 in Computational Biology! https://t.co/GN7RowCxr9

October 24, 2018

Join us for a symposium in honor of Dirk Eick on November 9 in Munich #transcription #cancer #epigenetics #chromatin https://t.co/EYT118lGTv https://t.co/Qq5HmWAa7d

October 16, 2018

Full house also for the discussion with Manuela Lenzen who presented her book on artificial intelligence and machine learning in the beautiful Paulinerkirche @Literaturherbst @thegoecampus @mpi_bpc https://t.co/zZzDLcnyfE

October 15, 2018

Hosting Germany‘s top energy economist tonight, Claudia Kemfert. Discussing her latest book on how to switch fast to renewable energy and fight climate change. @CKemfert @Literaturherbst https://t.co/Ij7b1BvL0M

October 11, 2018

Tom Steitz is well known for the work on ribosomes, but his lab also paved the way to an understanding of RNA polymerases with seminal papers in the 90s on phage enzymes. A real hero of molecular biology who will be sadly missed. https://t.co/xG2XMCugOR

October 08, 2018

Our structure of the Pol II-nucleosome complex reveals a defined nucleosome orientation and provides the starting point for understanding the mechanisms of chromatin transcription: https://t.co/0H2ZAOEhrV https://t.co/PgcBDZ6rwd

October 07, 2018

Congratulations to Salma Sohrabi-Jahromi for her poster award at the EMBL conference and thanks to the Söding lab for the collaboration on mapping RNA degradation factors on the transcriptome https://t.co/6r8rj6vDjZ

September 27, 2018

Our application with the University of Göttingen and the Medical Center UMG for a large national research cluster on Multiscale Bioimaging was funded, thanks to all who helped us! https://t.co/r32QK0hclf

September 25, 2018

Nucleosome-transcription factor interaction landscape mapped. Thanks to Fangjie Zhu and Jussi Taipale for the great collaboration! https://t.co/R5fAYAd4kd https://t.co/P8CEEXMa0R

September 21, 2018

Distinct multiprotein complexes form the 3'-ends of protein-coding and non-coding RNAs. Great collaboration with Lori Passmore's lab @lapassmore. https://t.co/i7cjzedivZ https://t.co/biOw3d3GSS

September 15, 2018

We contributed to an enjoyable science slam in the old city, featuring scientists from all five Max Planck institutes in Göttingen https://t.co/mWv2LesikZ

September 13, 2018

Tomorrow we celebrate the foundation of the Max Planck Society in Göttingen 70 years ago. Join us for a sciene slam at the local pub: https://t.co/J8eFsdmayT

September 12, 2018

Save the date for next year‘s Cold Spring Harbor Meeting on Mechanisms of Eukaryotic Transcription, August 27-September 01, 2019 https://t.co/y4DQ8j6bhX

September 06, 2018

Our new review on mitochondrial transcription includes the first molecular movie of the mitochondrial transcription cycle. Publication: https://t.co/ggkieyWkHb Movie: https://t.co/PGgLDQ4Bfz https://t.co/SGC8NoFHCH

September 05, 2018

Save the date: GRC conference on mechanisms of microbial transcription takes place July 28 to August 2, 2019 in Maine https://t.co/cKH1ZXXQK2

September 05, 2018

Investigate the switch from paused to activated transcription complex in 3D! Our new Pol II complex structures and density maps are available for download: https://t.co/p4vK1h28ed https://t.co/WP5WNcBTW7 https://t.co/VF1WYGR8CA https://t.co/1zaO0GcCUO https://t.co/Ff2SPNfUWX

September 02, 2018

@ProfJohnsen Really? When? This is sad for us.

August 31, 2018

Registration for the Structural Dynamics VIB Conference in Bruxelles ends in one week https://t.co/L94bI7vdWr https://t.co/IKItdeqZGx

August 23, 2018

Thanks to our colleague Karen Adelman for summarizing our recent findings on Pol II pausing and release and putting them into context: News and Views: https://t.co/LGxCbq6ZTU

August 22, 2018

Molecular basis of transcription regulation: our new papers elucidate promoter-proximal RNA polymerase II pausing and elongation activation by human DSIF, NELF, PAF, SPT6. https://t.co/0HXbgvZ1aL https://t.co/bWwGzcuXEr https://t.co/aJ4y5zyXRr

August 20, 2018

Our paper on RNA polymerase II clustering through CTD phase separation is now online. Thanks to the Zweckstetter and @XDarzacq labs for the great collaboration! https://t.co/429nhCSFwZ https://t.co/UzdWlDJguO

August 15, 2018

Congratulations to our Max Planck colleagues: Global animal tracking from space! https://t.co/nUaQ9HA51h

August 15, 2018

@animaltracking @Astro_Alex @AniMove @unikonstanz @maxplanckpress @icouzin @UWICER @MP_Innovation Congratulations on the great Tagesschau Beitrag!!

August 08, 2018

RNA velocity predicts the fate of single cells. Glad we could contribute to an exciting collaboration of the Linnarsson and Kharchenko labs @slinnarsson @KharchenkoLab https://t.co/3lYCBAL3dw

August 01, 2018

Many congratulations to Peter Scholze, our new colleage at the Max Planck Institute in Bonn, for obtaining the Fields Medal, the ‚Nobel Prize‘ in Mathematics https://t.co/T4cbNMIVwz https://t.co/x9qNrct9am

July 04, 2018

Council congratulates EMBL Barcelona for getting successfully started! https://t.co/xBolhBo3Gu

July 04, 2018

The Klenk Symposium on Epigenetics will take place October 4-6, 2018 in Cologne. https://t.co/lPVXMq0nup

June 24, 2018

The scandinavian #cryoEM symposium will take place in Copenhagen October 8-9, 2018 https://t.co/B0M74sDrgR

June 22, 2018

Save May 20-22, 2019 for the DNA damage response mechanisms conference in Madrid https://t.co/Cz1aeK6RkC

June 14, 2018

'Warp' software by Dmitry Tegunov closes the gap between the electron microscope and 3D density reconstruction. See our manuscript and user guide for automated real-time cryo-EM data pre-processing and particle picking https://t.co/h0vimmogWJ https://t.co/JWgrel6Jgd #cryoEM #Warp https://t.co/bv72UDxIPB

June 09, 2018

Vienna RNA biology meeting will take place October 17-19, see https://t.co/JvbahsZbhh https://t.co/bUMYtQ1eRR

June 07, 2018

Our next seminar series program is out, please save the dates and join. https://t.co/OVclPOY1x7

June 07, 2018

Many congratulations to our colleague at the institute, Jens Frahm, on winning the European Inventor Award! Do not miss their incredible movies made with real time MRI! https://t.co/UTx1087rR0

June 04, 2018

@benoitbruneau @Gene_Regulation TT-Seq we think

May 25, 2018

Our new review provides a movie of RNA polymerase I transcription that can be used for teaching purposes https://t.co/IBHN33r1LK https://t.co/cZGrd2F7pb

May 23, 2018

On the shoulders of giants: celebrating the ‚founding fathers’ of our field, Bob Roeder, Bill Rutter, and Pierre Chambon in Paris on the occasion of the 50th anniversary of the discovery of the eukaryotic RNA polymerases https://t.co/zDbIlwIObE

May 16, 2018

Many congratulations to Melina and our neighbors! https://t.co/ttWk4sUxcw

May 16, 2018

@SchuhLab @EMBO Great! Many congratulations!

May 10, 2018

@R_H_Ebright PDB took very long; we sent it to many colleagues by mail

May 09, 2018

Our structures of transcription initiation complexes with TFIIH and Mediator are now available for download: https://t.co/PyKXvc5Qvw https://t.co/H3Iy6lUMXQ https://t.co/mkq36fB76C https://t.co/zBuJf8fLLR

May 08, 2018

The RNA polymerase II CTD phase separates in vitro and governs polymerase clustering in vivo. Thanks to the Zweckstetter and @XDarzacq laboratories for this collaboration. Read the manuscript at https://t.co/vbfBgbeekf https://t.co/Gatul5SkaY

May 08, 2018

Great student-organized molecular biology meeting at Göttingen in fall https://t.co/nlqsxWPVG2

May 01, 2018

We are deeply saddened by the untimely passing of our great colleague Elisa Izaurralde, RNA biochemist at MPI Tübingen. https://t.co/dlPFpwDLdM

April 28, 2018

Join us on May 9 at 1 pm for the talk of Kelly Nguyen who just published the marvelous structure of human telomerase #cryoEM #RNA https://t.co/YgL5bMSj49

April 14, 2018

Marching for free and open science! https://t.co/uLp1NErfWD

April 12, 2018

Join the 2nd March for Science in Göttingen on April 14! https://t.co/s4ts3qa7oa

April 11, 2018

Patrick Cramer presents Kjeldgaard lecture in Aarhus, Denmark https://t.co/coKzWNsRKc https://t.co/1lLCHD7GbA

April 09, 2018

Christian Dienemann passed his PhD exam, many congratulations! https://t.co/Fyp1sY6QJI

April 03, 2018

Save December 5-7 for this year's epigenetics meeting in Freiburg https://t.co/kdnn53Lr6h

March 28, 2018

Congratulations to Hauke Hillen for obtaining this year's PhD Award of the German Society for Biochemistry and Molecular Biology for elucidating mitochondrial transcription! https://t.co/JIt0vs8Vca https://t.co/x5uvxnzdpy https://t.co/ZQgzFI1TW3

March 18, 2018

Our new cryo-EM structure shows why the mushroom toxin amanitin binds 3000-times better to mammalian RNA polymerase II than to the yeast enzyme https://t.co/G8ZC1jjQql https://t.co/HjMeJ5rILH

March 16, 2018

RNA polymerases 50 years on: save May 22 for the symposium in Paris https://t.co/yRYydGi1aD

February 19, 2018

Sandra Schilbach passed her PhD exam, presenting the pre-initiation complex structure, many congratulations! https://t.co/8ySgkDnhq5 https://t.co/x6vNm6zTvE

February 14, 2018

Congratulations to former lab member Clemens Plaschka who will start as a group leader at IMP Vienna soon! https://t.co/2FAyshTyjN https://t.co/uFgIaoRbQv

February 06, 2018

@TheVillaLab Many thanks for organizing this interesting meeting!

January 26, 2018

Congratulations to former lab member Christoph Engel on winning the Early Excellence in Science Award of the Bayer Foundation https://t.co/N73AqwnvUV https://t.co/s5qlOTUBdw

January 18, 2018

Congratulations to Vannini and Müller labs on the Pol III PIC structures!

January 17, 2018

Our Stockholm team moves into the new building ‘Neo’ at Karolinska Institute https://t.co/IDEnBPLNUj https://t.co/uEEgdQ3Oq6

January 16, 2018

Applications for PhD fellowships are invited by our new Max Planck Research School for Genome Science that brings together experimental and computational biologists https://t.co/pJXX0OarIp https://t.co/qEhIexHo4z

January 13, 2018

A good summary of our recent structure of the Chd1 chromatin remodeling factor bound to the nucleosome published in Nature Structural and Molecular Biology by Michaela Smolle https://t.co/QjddNtNJxa https://t.co/rd1daFUUch

January 03, 2018

Congratulations to Youwei Xu who takes on an Assistant Professor position at Shanghai Tech University https://t.co/Lt8DSBwD5w https://t.co/EH0ia3EHx5

December 29, 2017

Our paper with Jussi Taipale’s lab on the interaction landscape of transcription factors and the nucleosome is available https://t.co/lCWUigXIWK

December 21, 2017

Goodbye to Kayo Nozawa who takes a Research Associate position at Waseda University in Tokyo. https://t.co/dlGpakp4dI https://t.co/FgvAEPIl82

December 19, 2017

Christoph Engel starts his research group at Regensburg University in January 2018, funded by the Emmy-Noether-Programme. https://t.co/iUj53Wa7bT

December 18, 2017

Haibo Wang received an EMBO postdoctoral fellowship, congratulations! https://t.co/V3L6Gw8GYi

December 16, 2017

Xiaoguang Xue received an EMBO long-term fellowship, congratulations! https://t.co/a7TyDsHsCW

December 08, 2017

We host Julie Ahringer from Cambridge as our Christmas speaker https://t.co/0wqea2pnP3

December 02, 2017

Good-bye to Carrie Bernecky and all the best to her lab at IST Austria! https://t.co/JmnR57ySzB

November 30, 2017

Congratulations to the Max Delbrück Center in Berlin, it turns 25! #MDC25 https://t.co/Uh5I4Fipjf

November 16, 2017

Cell published our mechanism of transcription initiation in human mitochondria... https://t.co/zqj3shnIO0

November 08, 2017

Our institute hosts Kim Nasmyth for a Bonhoeffer Award Lecture https://t.co/Fuhqerv7po https://t.co/UwnZAAWclG

November 07, 2017

Patrick Cramer gives the Weigle Lecture in Geneva, where early molecular biology was done https://t.co/lJwrBmBTPb https://t.co/Ie5muCrOz2

November 06, 2017

Congratulations to Lucas Farnung and Hauke Hillen for passing their PhD exams! https://t.co/SkIrI70INX

November 04, 2017

From now on, updates on our facebook page will be shared on twitter

November 04, 2017

@nature published our milestone structure of a 46-subunit transcription initiation complex with TFIIH and Mediator https://t.co/3FtHLn0i44 https://t.co/Mj7cRwvIm7

November 04, 2017

From now on, our facebook page updates will be shared on twitter.