News
Lab News on Twitter (since 2017)
November 11, 2022
What a great evening. Thanks for coming, @JoeMillerJr! https://t.co/UnkSQbTWiZ
November 10, 2022
Looking forward to the panel discussion on enlightenment & the future of democracy. https://t.co/T1DOFARh3U
November 07, 2022
This is so great and so well deserved, congratulations to Dirk! https://t.co/I3wckDltfM
November 07, 2022
Important news: regulations to limit energy prizes in Germany will apply to scientific institutions! Many thanks to everyone who helped making this possible. @Leopoldina @BMBF_Bund https://t.co/rGP44HWpyX
November 06, 2022
Really great video on exoplanets featuring Max Planck colleague @lkreidberg @mpi_astro https://t.co/GBgYmS65lD
November 05, 2022
Although RNA exit path is wrong and many factors are missing, this movie gives a great impression of how RNA polymerase II copies genes to produce mRNA. https://t.co/bfXVKvfRmp
November 05, 2022
Looking forward to discuss PLANETARY HEALTH @Falling_Walls On Nov 8 at 4pm in Berlin. Register for free livestream: https://t.co/TCweTlAc10 https://t.co/DX2ovQadhu
November 04, 2022
Wonderful event with Antje Boetius @AWI_de on her life exploring the deep sea and addressing global challenges. https://t.co/zaJ5THrTDn
November 03, 2022
The place where gravitational wave physics started. Great opportunities for the future, incl. space detector LISA and synergy with quantum computing. https://t.co/DJAIoHpGpU
November 02, 2022
Many congratulations to @GargGaurika who passed her PhD defense, great manuscript on co-transcriptional pre-mRNA capping! https://t.co/f68YFfmcN6
October 28, 2022
Here is the current lab! From January 1st coordinated by @lidschreiber with teams of project leaders @EOberbeckmann @c_dienemann and Kristina Zumer https://t.co/B4nDHJ47F5 https://t.co/WIIW8MFr58
October 27, 2022
17th Cramer lab retreat featuring @drosoigmm @SchurLab @jankosinski and Maria Sokolova. https://t.co/mpDh6822my
October 25, 2022
Thanks to @LouisJeantetFDN for producing this video on our work: https://t.co/DyMGsQxkUR Featuring @Zhang_Suyang @MRC_LMB @isaac_fianu @HaiboWang36 @MariekeOudelaar @Stefan_W_Hell @mpi_nat and others. https://t.co/vO0SonqLjc
October 25, 2022
At the interface to biology, the @MpiciPotsdam invents bioinspired materials and a sustainable future of chemistry. https://t.co/pFLBBd5jew
October 25, 2022
It is one thing to hear about the fascinating nature of gravity but seeing a movie of two black holes merging is mind-blowing. https://t.co/KBEhD4bQeY
October 25, 2022
Insights into gene dose: mRNA and protein abundance scales allometrically with ploidy, i.e. tetraploid cells show only threefold increase in protein abundance. Glad we could contribute to this study by the Storchova lab. https://t.co/9Uw93ymvZY
October 24, 2022
Much looking forward to host Antje Boetius from Wegener Institute and @MarineMicrobio at Göttingen, join the live stream! https://t.co/YSA5dg6QEe
October 24, 2022
Plant science leads to fundamental biological insights and biotech applications. But it is also key to ensure food production and to obtain biomass for sustainable chemistry. Thanks for the warm welcome! https://t.co/TCE4qOOdt3
October 20, 2022
Looking forward to moderate the discussion! https://t.co/FEc3l8hJyq
October 18, 2022
Nice description of our lab's interdisciplinary research in the new issue of the Max Planck magazine. English version will follow. https://t.co/H7Ri3lBHY2 https://t.co/6GrrhL8Qw3
October 17, 2022
Ulrich Nauber organized art exhibitions at our institute @mpi_nat for 20 years! Great outreach as science and art are close relatives. https://t.co/mEPNAYO6Td https://t.co/dybUstMq12
October 16, 2022
Science enabled the development of tests, vaccines & drugs to fight SARS-CoV2. We must support science during the current crisis to be prepared for an unknown future. https://t.co/mo8pdnNmok
October 16, 2022
Help needed: Anyone knows the artist „C. Seeberger“ who drew this beautiful portrait of Max Planck in 1934? Just obtained this ‚lost’ original artwork from a colleague. https://t.co/flxhCkwjnG
October 15, 2022
@mkMellon I loved dreaming about densities and often figured out correct structural interpretations during sleep.
October 12, 2022
Spectacular talks by Sahin, Türeci and Kariko (on how mRNA vaccines became possible) were followed by a wonderful ceremony and dinner @LouisJeantetFDN in Geneva https://t.co/TGbwz17q7c
October 09, 2022
Glad to live in a country that can attract and foster brilliant minds like Svante Pääbo. https://t.co/FQMVJjKZki
October 08, 2022
„fund the best research despite the crisis“ - important interview on German radio @DLF with Max Planck colleagues Ute Frevert and @peterseeberger https://t.co/XSDRCgXHuy
October 05, 2022
Looking forward to give the Fred Richards Lecture at Yale today: "Transcription of the Genome" https://t.co/tAeZ8mH1JV via @yalemed
October 03, 2022
Many, many congratulations to our @maxplanckpress colleague Svante Pääbo, on receiving this year‘s Nobel Prize in Physiology or Medicine! It is a great recognition of Svante‘s pioneering work and visionary leadership. Glad I could just visit @MPI_EVA_Leipzig, the place to be. https://t.co/hyEW5xPvK6
September 29, 2022
Some spontaneous thoughts on the science of the future, on our working culture and on the dialogue with the general public. https://t.co/BzDCAjK3qF
September 29, 2022
Some remarks on science communication and why we invite scientists to the upcoming literature festival at Goettingen. In German though. https://t.co/LE3yKS6tbq https://t.co/DrTs7wJHO9
September 28, 2022
So happy we were involved in this incredible work by Julia Mahamid‘s lab visualizing translation at atomic detail inside cells by cryo-ET. https://t.co/SrlUcoTS7O
September 23, 2022
Important message by the president of the German National Academy @Leopoldina today: high energy prizes will hurt research and endanger science. https://t.co/z4NINYBi5g via @derspiegel https://t.co/O4qeB5gEX8
September 22, 2022
What an honor to speak af this symposium with @erin_schuman, Catt try ol Robinsson, Ugur Sahin, Özlem Türeci and Katalin Kariko. https://t.co/Sf4Ry2J2FB
September 22, 2022
Saying goodbye to @YingChen_P and @KokicGoran who both take positions. Many thanks for the great contributions and many congratulations! Hopefully this is not the last rooftop barbecue this year. https://t.co/PMM7bmsjgO
September 22, 2022
Many congratulations, Tony and @HymanLab! https://t.co/qaY1DsXZ8d
September 22, 2022
First structural insights into how a NON-coding RNA promoter is recognized and opened by Pol II - without TFIIH but using the specialized factor SNAPc. Great work by @vasan06 in collaboration with @VanniniLab https://t.co/KI6ZvG5mGQ https://t.co/TsyStoIWKW
September 22, 2022
Wonderful opportunities to develop the life sciences and for interactions with @LMU_Muenchen @LMU_Uniklinikum @BioM_Munich @GeneCenter_LMU https://t.co/rs0d0qkvNL
September 22, 2022
The new @MPIforBI studies the mystery of biological intelligence at two sites south of Munich, our life sciences campus in Martinsried and Seewiesen, where this beautiful lake and surroundings allow for animal observation in a natural habitat. https://t.co/6OwIrv9q9A
September 18, 2022
Learned more on where we stand with quantum computing at the amazing @MPI_Quantum. In the current hype it remains open which technology will prevail to ‚store’ qubits - but it is clear QC will be superior to traditional computing for several applications. https://t.co/2DkT9r2F1e
September 16, 2022
How do animals interact, move globally and behave collectively? A fascinating combination of biology, technology and computing unravels many secrets. @MPI_animalbehav hosts outstanding research group leaders with unconventional ideas! https://t.co/SxKGJQEZpG
September 16, 2022
Exciting to meet @zieglerphoto1 today @MPI_animalbehav, who obtained this year‘s World Press Photo Award for Nature, congratulations! https://t.co/xcB1RGyKFA
September 15, 2022
In direct neighborhood of @MPE_Garching, the MPI for Astrophysics focuses on theoretical work to understand the origins of the universe and the development of galaxies and stars. https://t.co/fzmZZRl5od https://t.co/yRJtO06332
September 15, 2022
How do they know the plasma inside the Tokamak fusion reactor is at 100 Mio degrees? They built this huge „thermometer“ @PlasmaphysikIPP. And they made the heat shield of tungsten, an important contribution to @iterorg https://t.co/nRrQOQ38z3
September 15, 2022
Movies of stars accelerated by black holes, maps of dark matter in the universe obtained with X-ray detectors in space, and chemistry on distant planets! https://t.co/NoQTnazxlD
September 14, 2022
Looking forward to host Antje Boetius, Özlem Türeci and Ugur Sahin this year! https://t.co/1tr27OpAEh
September 14, 2022
Founded by Einstein and reestablished by Heisenberg the MPI for Physics is world-leading in particle physics. The insitute was also instrumental in bringing to life the MPI for Astrophysics @PlasmaphysikIPP @MPE_Garching https://t.co/tEWiP4zsSb https://t.co/ONHcykFZ0q
September 09, 2022
Deeply impressed by the work @MaxAnthropology, aimed at understanding human cultures around the world. Researchers often spend a full year abroad. Also great outreach activities: https://t.co/y26gvEWq45 https://t.co/50cM7gPDpu
September 08, 2022
Facing questions by students on climate change and personalized medicine: it is one thing to develop technologies and therapies, but we also have to change the way we live. https://t.co/s2hAq9RXNk
September 08, 2022
Mathematics is often the key to enable breakthroughs in others disciplines, not only in biomedicine or physics, but increasingly also in the social sciences and beyond. This becomes obvious seeing the many interactions of @mpiMathSci with other institutes. https://t.co/TVhRcAeEH9
September 07, 2022
Where paleogenetics was developed and human history is lined out in an unprecedented way. @MPI_EVA_Leipzig https://t.co/Yfn2yeq08j
September 06, 2022
Astonishing encounters with our close relatives at the Wolfgang Köhler Center, the largest primate observation research center, hosting 50 animals. A collaborative project of @MPI_EVA_Leipzig & @Zoo_Leipzig. https://t.co/DIjwMfaIW6
September 05, 2022
What makes us human? Perception, language, learning and memory are focus areas at the MPI for human cognitive and brain sciences in Leipzig. Home of @MPS_cog. https://t.co/7c3DF9Kfsm https://t.co/WqVNYfBMYx
September 05, 2022
What an honor to speak in a symposium with such distinguished colleagues https://t.co/QDdc78Otqv
September 05, 2022
Thank you for hosting us and all the best for the future! https://t.co/Mmh6MpI3fI
September 04, 2022
After visiting the first 15 institutes, it is clear many postdocs wish to have advice on alternative career paths. Please use offers by @maxplanckcareer and provide feedback. @MPGpostdocnet https://t.co/9Gjy1eeuR3
September 02, 2022
Many congratulations, Tony! https://t.co/H8lLVGAaOj
September 02, 2022
Great to see how the 111-year old MPI for Medical Research develops, incl. the planned new building at the Neckar river in Heidelberg. For me, it will always be connected to the introduction of synchrotron radiation to structural biology by Ken Holmes. https://t.co/TrhrciW2Ek https://t.co/tPRpZMnmOp
September 01, 2022
The only place on our planet to do chemistry under the conditions of interstellar clouds: the MPI for Nuclear Physics next to @embl in Heidelberg. Colleagues here also study mysterious dark matter and other phenomena that are well beyond my understanding. https://t.co/8TJ84JcQZW https://t.co/1YYvTaydRZ
September 01, 2022
The workshops @mpi_astro build instruments for telescopes icl. @NASAWebb, allowing colleagues to study exoplanets and the birth of galaxies and planets. Touching fundamental questions of our existence. https://t.co/hnUVWxoAAR
August 31, 2022
So obvious here how science can help make the world a better place. Peace efforts in Sudan, constitutional advice for states in Latin America or global animal rights: so many important implications of the research carried out @MPILheidelberg - thank you for these insights! https://t.co/lLZiNB7BIn
August 27, 2022
Great to be back and meet several alumni who present stories from their labs! https://t.co/fIQOcCyPqq
August 27, 2022
The program for our Literature Festival #Literaturherbst is out, including Özlem Türeci and Ugur Sahin of BioNTech on November 02, presenting „Project Lightspeed“ - the story of how the first corona vaccine became possible. https://t.co/IxYYzJi8BL https://t.co/8nKXjR0UZj
August 26, 2022
@GiuCali_ @CSHL @sroka_martyna @CAMarshall480 @cshlmeetings What a wonderful colleague, it all started with crystallography and RNA
August 26, 2022
I learned, amongst other things, how analysis of a sample from 2300 water depth questions our current tree of life and understanding of eukaryote evolution. So much to be discovered in the ocean. Thank you for the stimulating discussion. https://t.co/vRM2HqGA7l
August 25, 2022
Located in Hamburg, @MPIPRIV has unique expertise in private law for numerous countries, competence centers for China and the islamic world, amongst others, and an impressive library that attracts ~1000 guest researchers each year. https://t.co/8Ea2FW3F71
August 24, 2022
What a privilege to be part of the first event held in the brand-new building @MPSDHamburg - the place to be for studying the structure and dynamics of matter on a large campus with strong partners @CFEL_Hamburg @unihh @desy @CssbHamburg @embl https://t.co/tw05lkqQvV
August 24, 2022
Moving to visit the place where the foundations were laid to proof that global warming is a result of human activity, eventually leading to the Paris Agreement in 2015. Today continued outstanding research on climate modeling with big data, really critical for our future. https://t.co/JHpAQsXIi3
August 23, 2022
Impressed by @MPI_Muenster after meeting Dietmar Vestweber, @WickstromLab and @ralfhadams. Biomedical research including work on tissue morphogenesis and dynamics. https://t.co/PfgTzl5BJb
August 18, 2022
A glimpse of the future when visiting the MPI for Security and Privacy - topics range from cryptography to digital wellbeing. Strong local partner @ruhrunibochum https://t.co/d6GQ3b34tg
August 18, 2022
The @mpimoph not only conducts leading research in cellular, structural and chemical biology; it also enables large-scale robotic compound screens and lead discovery through COMAS and LDC. https://t.co/sMZIDUciE1
August 17, 2022
Good-bye to @Zhang_Suyang & wishing her all the best for her lab @MRC_LMB - she solved the first transcription-splicing structure & will continue on this. https://t.co/QZjxRDJnIg https://t.co/HLAJLWW59u
August 17, 2022
Very impressed by the MPI for Mathematics in the center of Bonn: 4 colleagues (of whom 2 obtained the Fields Medal) attract hundreds of guest scientists from around the globe each year. https://t.co/muw2k3lQhJ
August 12, 2022
@MPI_Metabolism not only does great science but also builds bridges to the hospital and creates strong synergy with the neighboring @MPIAGE https://t.co/rkv69QJV7v
August 12, 2022
Thank you for hosting us! Great discussions on how to best support our group leaders. https://t.co/7rDZDB0Rp5
August 11, 2022
Fascinating start of our tour of Max Planck Institutes in Bonn: Behavioral law and economics study how we judge and take decisions https://t.co/h9CjcKCFMm https://t.co/AzWNedUsEc
July 25, 2022
Sharing the piece I wrote on the occasion of the 100th anniversary of Franklin‘s birth: https://t.co/6cos60sqeO https://t.co/STkk7Ws32b
July 19, 2022
#Nucleosome passage by Pol II: H2A/H2B loss, backtracking and TFIIS-mediated reactivation. Finished in a transatlantic collaborationbetween @LucasFarnung @MoritzOchmann @GargGaurika @seyvos https://t.co/dTmqSNMHnm https://t.co/HZfOyOxn7h
July 15, 2022
Honored to witness today how Planck joins Gauss at the hall of fame ‚Walhalla‘ in Bavaria https://t.co/07bnNXbOd8
July 14, 2022
Feels surreal to hold a copy of Galileo Galileis ‚Discorsi‘ from 1655 in hands. One of the treasures of @MPIWG. https://t.co/Miw3PUAvez
July 06, 2022
Many congratulations @RehlingLab, newly elected member of @EMBO! https://t.co/iQ1sHyKpy4
July 06, 2022
Thank you for the invitation, @BioM_Munich and congratulations on 25 years of the Munich Biotech Cluster. https://t.co/gFnZBt2rXK
July 01, 2022
Saying good-bye to @HaiboWang36 and wishing him all the best as a PI at @ZJU_China. Remembering his wonderful work on chromatin-associated factors: https://t.co/q6HbhPcA6v https://t.co/L6ylxm92zV https://t.co/74gE4xiVZr https://t.co/R7LTHzrjo4
July 01, 2022
So well deserved. @KokicGoran solved much of the mystery of TCR. All the best for the future! https://t.co/prJksS9LKG
June 27, 2022
Explaining gene transcription in German TV in 13 minutes… https://t.co/3t4F9CWJJu https://t.co/INSUl5WLGv
June 23, 2022
Honored to serve science and society as next president of @maxplanckpress and looking forward to visit our 85 institutes and prepare for my term. https://t.co/f8LliT2nWs
June 22, 2022
Very grateful to past and present lab members for their contributions. Wonderful to see many of them excel in their own labs. https://t.co/gK0gJLNZW0
June 20, 2022
What a memorable event, and so great to share with two close colleagues and friends. https://t.co/A8Ue4eDodh
June 17, 2022
Congratulations @msanderlab - and all the best to @MDC_Berlin https://t.co/6iMQhv6HwL
June 12, 2022
Looking forward to speak at the Aminoff Symposium in Stockholm on Tuesday. Programm: https://t.co/TpKrSSrJid https://t.co/8eetRgvj29
June 05, 2022
Very impressed by the newly opened @ForumWissenGoe - a place teaching the scientific approach @uniGoettingen @thegoecampus https://t.co/fMWYCk9x5N
June 04, 2022
Honored to join the Berlin-Brandenburg Academy of Sciences and Humanities. https://t.co/vgh35mThS7
June 03, 2022
Many congratulations to Eusra Mohammad who just passed her PhD defense! Fine contributions to multiomics analyses of transcription-related CDKs. https://t.co/gpCTjhL2kk
June 02, 2022
Looking forward to discuss the future of biomedicine at Munich on July 5-6. https://t.co/feK09HwoW4 @BioM_Munich https://t.co/LcYivwm6eb
June 01, 2022
Thanks @plaschka_lab @AlexanderStark8 @IMPvienna for organizing a great day of exciting science. https://t.co/epmSN1hLPg
May 27, 2022
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells. Fine collaboration of @LeXiong @lidschreiber @taras_velychko @LCaizzi with Schöler lab. https://t.co/paVNCaoK3z @eLife
May 26, 2022
Thanks for the warm (!) welcome and interesting science https://t.co/Cylo1lfrcz
May 25, 2022
Much looking forward to visit @IMPvienna, give the Birnstiel lecture and meet many colleagues incl. @plaschka_lab @AlexanderStark8 https://t.co/1TPFla7ES3
May 19, 2022
Finally big lab party again https://t.co/zHnWUAqzYy
May 17, 2022
Structures of nucleosome arrays suggest that H1 binding depends on length & trajectory of linker DNA. This can explain why arrays with short spacing are H1-depleted & suited for transcription. @mdombro_ @Sveta_Dodonova @c_dienemann Paper: https://t.co/Mr6c0WO5WS https://t.co/ws2N9cl30O
May 12, 2022
Looking forward to host Titia de Lange from @RockefellerUniv for our Bonhoeffer Award Lecture @mpi_nat next Tuesday. https://t.co/srGVXVey5e https://t.co/wmrQ17Hfc3
May 11, 2022
So great to have @mleptin as president of @ERC_Research, congratulations! https://t.co/UD2LVUDlRY
May 10, 2022
mRNA vaccines became possible based on decades of basic research. Celebrating @Helmholtz_HIRI @Helmholtz_HZI with @JoergLab at Würzburg residence. https://t.co/XC0Oyo1np2
May 08, 2022
#Ukraine️ national colors east of #Göttingen campus. https://t.co/L6vog1NK4T
May 08, 2022
„I come with a wish: foster diversity and understanding“ - Andreas Görgen (BKM) at the grand opening of the Göttingen Literaturhaus. https://t.co/bXE1FR9jhK
May 04, 2022
The talks given at the @Leopoldina #COVID symposium are now available online: https://t.co/wiyQrAcwaG
April 29, 2022
Thanks to colleagues in the DNA repair field for the invitation. In the future, @KokicGoran may be a frequent participant. https://t.co/vZ5Z1tlDiV
April 27, 2022
Huge Thank You to Steven Cusack and best of luck to Kristina Djinović-Carugo! EMBL Grenoble is close to my heart - great memories from PhD times. https://t.co/0hoy5yF8Ia
April 26, 2022
Looking forward to host our new Federal Minister of Science @starkwatzinger @mpi_nat for a round table discussion on May 5. https://t.co/OhqD6GYrgC
April 22, 2022
Saying good-bye to @mdombro_ with a rooftop barbeque! https://t.co/RW4qaTUpM3
April 19, 2022
Here is the future! https://t.co/I3yWRqBRTf
April 07, 2022
Great honor to give this lecture in memory of our colleague Elisa Izaurralde. https://t.co/CzrnLGBDke
April 03, 2022
Congratulations to @hauke_hillen for receiving the Engelhorn Research Award 2022 tonight in Munich! https://t.co/PJD5o6fhyQ
April 02, 2022
Congratulations to former lab member Kayo Nozawa who just started her own lab at Tokyo Institute of Technology @NozawaL https://t.co/sPzvIb4pUm
March 29, 2022
Polymerase in action. Looking forward to the TV recording later tonight. https://t.co/lmuxCFZCeU
March 21, 2022
The talks of the cryo-EM workshop at Academia dei Lincei are now online. Keynote lecture starts at 3.01: https://t.co/TKtJtQ9YZB https://t.co/o50T38jHE7
March 18, 2022
Looking forward to give the closing keynote at the cryo-EM workshop of the ACCADEMIA LINCEI today at 5.15 pm CET. Livestream: https://t.co/yYvCobHQ3o https://t.co/yadxknnQsK
March 18, 2022
Looking forward to close cooperation. https://t.co/ud8GxBiV2T
March 17, 2022
TT-seq measures synthesis and degradation of Alu retrotransposons. Glad we could contribute to this fine work of the Tresch lab. https://t.co/sa9ZdLKyZe https://t.co/Wszjy25sji
March 16, 2022
Save the date: EMBL Conference Transcription and Chromatin, taking place August 27-30, 2022 in Heidelberg. So much looking forward to meet close colleagues in the field again. https://t.co/zRW1G95x4E via @embl
March 07, 2022
@AsifaAkhtar1 Many congratulations, Asifa!
March 04, 2022
A famous alumnus of the University of #Odessa, #Ukraine, is George Gamow. He later worked at Göttingen and contributed to solving the genetic code. https://t.co/xiHBnNyoad
February 26, 2022
‘A step to nowhere’: Russian scientist organizes protest of Ukraine war https://t.co/NywT60ahbQ
February 21, 2022
Happy we could contribute to this new study from the lab of Jussi Taipale that uses massively parallel reporter assays to unravel sequence determinants for transcription activity and transcription factor function. https://t.co/nVkAL7ViOx
February 12, 2022
3 years ago I could visit this field station at the Beagle Channel near Ushuaia and understood a little better how traveling around Patagonia may have helped Darwin to come up with his revolutionary ideas. #DarwinDay https://t.co/IrFOwtV4te
February 09, 2022
The lab of @ZStorchova shows that mRNA and protein abundance scales allometrically with cell ploidy. Glad we could contribute. https://t.co/Gj6IbuztV5
February 04, 2022
On the shoulders of giants: Ken Holmes started as a PhD student with Rosalind Franklin and later introduced synchrotron radiation to X-ray crystallography, what a step. https://t.co/k7O690plB8
February 02, 2022
Movie by @KokicGoran shows how a protein complex (Pol II TCR complex) gets targeted by ubiquitination. https://t.co/yxFuhhUXpF https://t.co/sBSVLYIzM5
February 02, 2022
Great to see Roger still uses the initial ribbon model image of the core Pol II crystal structure from 2000 in his talks. Great memories. https://t.co/m14cD6kQv8
February 01, 2022
„Anyone can identify Karikó in retrospect, given her persistence and her eventual discoveries. But what do we do right now to find the 2022 versions of Karikó…“ https://t.co/AITd6cBElD via @statnews
February 01, 2022
This one of the top Max Planck projects in this decade. https://t.co/12n7kCrnw3
January 19, 2022
Congratulations to my colleagues @embl @emblebi on this ambitious and timely program! Best of luck! https://t.co/zZyujvslu4
January 19, 2022
Congratulations to the new life science factory that was just opened at Goettingen. https://t.co/vC4vhEorVB
January 18, 2022
After two years of zoom I much look forward to meeting colleagues again and hope we can travel to this exciting meeting on DNA repair mechanisms. https://t.co/Fj7DOZOTGr
January 15, 2022
Podcast on molecular evolution by Susanne Rostosky (German): https://t.co/2n2KJHyQm5 Happy I could contribute with our old study (Lehmann et al. Nature 2007): https://t.co/QzOKi5OThu
January 07, 2022
New interview on the latest on #SARS_CoV_2 #Covid_19 drugs #remdesivir #Molnupiravir #paxlovid (in German). Thanks to @gunnar_heine and colleagues. https://t.co/e4p5bIiJdX https://t.co/V1FdAiiEeU
January 05, 2022
The talk by Maja Göpel @beyond_ideology held on Nov 2, 2021 at #Literaturherbst is now available online (in German) at https://t.co/02K3m1xfGe https://t.co/LFt3zkjP12
January 01, 2022
It is an honor to serve as managing director of our new Max Planck Institute from today. I thank my colleagues for their trust and look forward to an exciting year. https://t.co/VvhPYOQWpu
December 17, 2021
Many congratulations Le Xiong for passing the PhD defense and all the best for the future! https://t.co/wWlqLXp1lt
December 16, 2021
Save the date: "Transcriptional regulation: Chromatin & RNA polymerase" Sept. 29–Oct. 2, 2022 in Snowbird, Utah. https://t.co/SSzLLWTDHy
December 09, 2021
So sad to say good-bye to Christina, Paulina, Felix, Sandra and Marc… but very happy they all found very good jobs. Many thanks indeed and all the best for the future! https://t.co/gGl0GMXf80
December 01, 2021
Marco Dombrowski passed his defense today, many congratulations and all the best for the future! https://t.co/5iHuN7co4V
November 30, 2021
This is so well-deserved, many congratulations! https://t.co/UORKWRs4DC
November 27, 2021
#molnupiravir will not be a game changer in fighting #SARSCoV2 as its efficacy is low. Highlights need for developing new #antivirals targeting #coronavirus polymerase. https://t.co/GLDwNLYxdm
November 25, 2021
"Free, curiosity-driven basic research is the foundation of public research funding" - an important statement of the new German coalition #Koalitionsvertrag https://t.co/TqcT7L5ETg
November 13, 2021
Extremely sad. Terrible we lost such a wonderful and always supportive colleague @thegoecampus. My thoughts are with Ulf Diederichsen‘s family. https://t.co/qYhDjkiqSg
November 11, 2021
Great to see how Integrator embraces the paused transcription complex to engage with nascent RNA and trigger Pol II attenuation. Paper by @isaac_fianu et al. edited by @dijiang319 is out @ScienceMagazine: https://t.co/hx8rb9Awly https://t.co/cbmLswOWsA
November 09, 2021
One minute of standing ovations after an incredible talk by Özlem Türeci of BioNTech on how mRNA vaccines became possible @Falling_Walls https://t.co/Kv4fakFX5t
November 08, 2021
My recent keynote “Towards a mechanistic understanding of genome regulation” @MRC_LMB is online: https://t.co/nqCJj6CGCH https://t.co/hZhnhupnZi
November 04, 2021
Much looking forward to discussing #SARS_CoV_2 replication and #COVID19 antivirals with @LoellChristiane and Christian Spahn at @Falling_Walls on November 8 in Berlin. https://t.co/SVjmE9ph6P
November 03, 2021
Lively discussion on economic and ecologic transformation yesterday night with Maja Göpel @beyond_ideology - science and society event @mpi_bpc and Literaturherbst Göttingen. https://t.co/3WOEHNlbIK
October 30, 2021
@lianafaye BioNTech?
October 27, 2021
Honored to join Ugur Sahin of BioNTech and Tzachi Pilpel @TPilpel @WeizmannScience for the Max Planck Forum on „#Covid19: From Vaccination to Medication“. Online on Nov 11, 2021 at 6.30 pm CET. https://t.co/qRQRptLedt https://t.co/FIEAgd1nOZ
October 27, 2021
Very much looking forward to host Maja Göpel next week and discuss her vision of societal and economic transformation. https://t.co/33SNmeo5wG
October 19, 2021
Our institute is hosting Tom Cech today for the Manfred Eigen Award Lecture: Cryo-EM of a telomeric complex and RNA as a regulator of epigenetic silencing https://t.co/GYdgO02bJb
October 14, 2021
The paper by @KokicGoran et al. on DNA transcription-repair coupling is now available open access: https://t.co/G2UgJx8GiL Watch the conversion of the Pol II elongation complex EC* to a repair-competent EC-TCR containing CSB, CSA, DDB1 and UVSSA: https://t.co/TSlydWOrjG
October 14, 2021
Looking forward to speak at #FallingWalls21 in Berlin November 7-9, 2021 to present our contribution to #ScienceBreakthroughs on #coronavirus #SARSCoV2 antivirals. Event information: https://t.co/dCAdHCypAs Video abstract: https://t.co/N9SdlpdMuA
October 13, 2021
New article on the current discussion on the impact of #AlphaFold on structural biology (in German): https://t.co/nf904J6lFo
October 08, 2021
Congratulations to former lab member @ClausDKuhn for obtaining a professorship at University of Bayreuth! https://t.co/WoYaCAWRqB
October 07, 2021
So happy to have a REAL group retreat again! Many people have left and taken positions and many new ones have joined. Great opportunity to rethink our science. https://t.co/7aARD4YB0w
October 06, 2021
Much looking forward to our lab retreat at Berlin starting tomorrow! Hosting as speakers rising stars @_taktas_ @MariekeOudelaar @luijsterburglab @KovtunOleksiy https://t.co/sG3RkKC30X
October 06, 2021
Good summary by @Fischblog of the chances and risks of #molnupiravir treatment of #COVID19 patients (in German). https://t.co/VJ0bzx64Qv
October 05, 2021
Congratulations, Seychelle! https://t.co/eMW09zT9Qh
October 05, 2021
Many congratulations and welcome to our new postdoc, Shen Han @s_Han7! https://t.co/yuhLGK7Erq
October 04, 2021
The program for our new seminar series is out! Looking forward to host @YuanHe_NWU @canardbruno @Beck_Laboratory @LabConti @RobKlose @AdelmanLab & Xaohua Shen @Tsinghua_Uni https://t.co/ajIFzJIiyk
October 04, 2021
The talks from the symposium at @StJude ("Bringing Chemistry to Medicine") are now available online: https://t.co/y8NgihaMH9
October 01, 2021
Encouraging results for the antiviral #molnupiravir: oral treatment of #covid19 patients reduces risk of hospitalization by ~50%. We had previously described its molecular mechanism: https://t.co/EcB9ow6cn2 https://t.co/nfckng4r4C
September 30, 2021
@NietoAngela @MichelaBertero @lorealspain @CSIC @UniversidadMH Many congratulations, Angela!
September 29, 2021
@hecklab @Pittcon @asmsnews @OmicsNL Many congratulations, Albert!
September 29, 2021
Looking forward to today‘s virtual Next Generation Biophysics Symposium @MRC_LMB @imperialcollege https://t.co/zqzldTwAQO https://t.co/wfemLwhI8Z
September 24, 2021
Congratulations to our postdoc Suyang Zhang @Zhang_Suyang for obtaining a Group Leader position @MRC_LMB! All the best! https://t.co/JzXdCwmAxF
September 17, 2021
Saying good-bye to @Sveta_Dodonova who starts her lab @embl in Heidelberg soon. Many thanks indeed & all the best for the future! We will miss you. https://t.co/zPLusLup1A
September 17, 2021
Pol II can form inactive dimers: the stalk of one Pol II copy binds the active centre cleft of the other Pol II copy, and vice versa. Maybe an inactive storage form of the enzyme? @shintoez @c_dienemann https://t.co/6OgeDMbXny https://t.co/gui7jcuvMS
September 15, 2021
@TriggerLoop The yeast work is highly appreciated and fits well but unfortunately we had to limit references due to length restrictions.
September 15, 2021
Transcription-coupled DNA repair: After a long journey, we can now see how CSA, CSB, UVSSA and CRL4 remodel the transcribing Pol II complex for ubiquitination and DNA repair. Masterpiece by @KokicGoran. https://t.co/G2UgJwR5rd https://t.co/j8p9gv7YW3
September 14, 2021
Very honored to receive the Aminoff Prize of the Royal Swedish Academy together with my close colleagues Elena Conti @MPI_Biochem and Seth Darst @RockefellerUniv. Grateful to many past and present coworkers @CramerLab, colleagues at @mpi_bpc and @maxplanckpress for all support. https://t.co/03tS7pto1J
September 14, 2021
Looking forward to this year's Literature Festival hosting Maja Göpel @beyond_ideology. You can get online tickets and practice your German - but there are also a limited number of seats available. https://t.co/7BCEFpBU8C https://t.co/JdcDpvSS4h https://t.co/ace5EFPfWq
September 14, 2021
#Molnupiravir : coding for catastrophe - very informative news&views article by Liz Campbell on recent work from Götte lab, @HoebartnerLab and us in Nature Structural & Molecular Biology https://t.co/z3nqMuuUrm
September 10, 2021
So incredible: on his 80th birthday symposium, Ernst-Ludwig Winnacker explains his PhD work on the synthesis of vitamin B12! @GeneCenter_LMU https://t.co/glvQk1FRAb
September 06, 2021
Structural basis of RNA processing by human mitochondrial RNase P now revealed by @BhattaArjun2p and @hauke_hillen. Glad we could contribute to their newly published paper: https://t.co/lp8l62byWO
August 30, 2021
So much looking forward to the Cold Spring Harbor Mechanisms of Eukaryotic Transcription virtual meeting starting tomorrow! #moet2021 https://t.co/Rk44G2RYVZ
August 24, 2021
@royalsociety @SjorsScheres So well deserved
August 24, 2021
The #coronavirus polymerase can dimerize via its nsp7 subunit when one nsp8 subunit is lost. We speculate the antiparallel dimer facilitates template switching during sub-genomic #SARSCoV2 RNA synthesis. Thanks to team #COVID19. https://t.co/7vPRr6E8xf https://t.co/3Llq9lDWy7
August 21, 2021
B12 was the first structure I saw in 3D when I was a student at the University of Bristol in 1992. I was so taken by its beauty that I moved to crystallography. https://t.co/nclhaGLEH6
August 19, 2021
August 19, 2021
@OWitzig Nein, Medikamente werden nur ergänzend sein, bitte vor dem Herbst dringend impfen lassen.
August 19, 2021
Good summary of our recent studies of #molnupiravir (in German) https://t.co/iFUJ3kn1Ld via @BR24
August 17, 2021
This year’s Horizons meeting organized by our young scientist community is approaching: @HorizonsMolBio @mpi_bpc https://t.co/1Gb35NJA6H
August 16, 2021
Molecular mechanisms of #corona drug candidate #Molnupiravir Free access link to paper: https://t.co/i0kRkVBKNc Press release: https://t.co/Ix6abGdlSR
August 14, 2021
Free access link for AlphaFold2 and the future of structural biology https://t.co/stutNXHvrv
August 11, 2021
#molnupiravir is a #COVID19 drug candidate that targets #SARSCoV2 polymerase and causes #coronavirus mutagenesis. In collaboration with @HoebartnerLab we provide the mechanism of this phase III #antiviral: https://t.co/EcB9ow6cn2 https://t.co/49C9z4Upvh
August 10, 2021
#alphafold2 is based on @PDBeurope and is testimony to the power of open science. The marvelous resource provided by @DeepMind and @embl @emblebi is a seminal example of how transformative research may be done to the benefit of society. https://t.co/TyxVZc0lbX
August 02, 2021
Welcome to the lab, James! https://t.co/GLS6Jej8hv
July 30, 2021
@TheresiaBauer Danke, ein wichtiger Schritt!
July 29, 2021
@CeMM_News @georg_e_winter Congratulations, Martin!
July 28, 2021
July 28, 2021
Many congratulations, Ernst-Ludwig Winnacker, and thank you for all your great efforts to foster excellence in European science and to promote early scientific independence in Germany! https://t.co/CcCMxhbgQf
July 27, 2021
@DrReneHeller @MPSGoettingen Welcome to Goettingen
July 24, 2021
TBP binding to a nucleosome, assisted by TFIIA. Unexpected structures and their implications by @HaiboWang36 now online: https://t.co/n7MBvRTsGZ https://t.co/1VVkEeJ54F
July 22, 2021
@TriggerLoop @ArndtLab Many thanks for writing this, Karen and Craig!
July 19, 2021
Looking forward to the Harden Conference "Machines on Genes" that takes place May 22-26, 2022. https://t.co/ZHqZGrcONm https://t.co/QcNuC4TrXn
July 16, 2021
Save the date: Sept 29-Oct 02, 2022 Transcriptional regulation: Chromatin and RNA polymerase II - ASBMB meeting in Snowbird, Utah https://t.co/SSzLLWTDHy
July 16, 2021
Finally! 1 1/2 years later we can again celebrate together in a local restaurant! https://t.co/WtFOHPgmDg
July 14, 2021
Super Elongation Complex binds RNA polymerase II lobe & protrusion to stimulate transcription allosterically. Comprehensive structure-function analysis by @YingChen_P et al.: https://t.co/J1ICd86fO2 https://t.co/WRCEGFS1Eh
July 13, 2021
Please trust in science and get vaccinated! It works: Last winter old people were vaccinated in Germany and they were protected from #SARSCoV2 in spring (@rki_de & @DIEZEIT). https://t.co/RDWHToQ4Uf
July 13, 2021
Many congratulations to @FKabinger who received a Boehringer Ingelheim Fellowship today! https://t.co/68BLIJcYGs
July 13, 2021
Looking forward to give a lecture at @UniLeipzig today at 4 pm CEST: https://t.co/rtHD3caX9h https://t.co/M3HFIQ4jmP
July 07, 2021
Celebrating 50 years of the Protein Data Bank on 20-22 Oct 2021, register now: https://t.co/K3vOVtdOZq
July 06, 2021
Sara Martins @SaraMM_4 passed her PhD defense, many congratulations! Great presentation on how splicing influences transcription, her work with @LCaizzi: https://t.co/qloGaLq6u1 https://t.co/eP0pACxJt0
July 02, 2021
Much looking forward to the virtual symposium „Bringing Chemistry to Medicine“ on July 22-23 at St. Jude. https://t.co/UWHnuiqzdF
June 29, 2021
@ewanbirney Unfortunately true
June 28, 2021
Multiomics shows that the pluripotency factor #Oct4 primarily controls enhancer activity and not accessibility. Fine collaboration of Le Xiong et al. with @Tolen13 in the lab of Hans Schöler @MPI_Muenster. Preprint: https://t.co/7jjUAvqkkA
June 24, 2021
On our YouTube channel you can now find recent lectures, special events and videos about our research. https://t.co/1HVVLqW7hP
June 22, 2021
@shengfui Warum wurde überhaupt gefragt?
June 20, 2021
We have to say good-bye to @LCaizzi, thanking her for pioneering work on the in vivo kinetics of pre-mRNA splicing and its coupling to transcription and wishing her all the best for continuing her career at Turin, Italy! https://t.co/jmw79mjhYV
June 18, 2021
PAF and SPT6 stimulate human transcription elongation in distinct ways. Whereas PAF subunit RTF1 stimulates Pol II velocity, SPT6 stimulates Pol II passage through nucleosomes. Congratulations Kristina Zumer et al.! https://t.co/PBaKf2Afyn https://t.co/joXEOvKHsd
June 15, 2021
It’s the year of the #PIC: Yeast Pol II pre-initiation complex at 2.9 Å resolution defines a unique mechanism of initial DNA opening. Tour-de-force by @S_Schilb with help from @shintoez & @c_dienemann. Download the paper here: https://t.co/LA781MSkqE https://t.co/wSrJIVQCvR
June 09, 2021
U.S. signs $1.2 bln deal for experimental #COVID19 drug #molnupiravir. We provide the molecular mechanism for free. https://t.co/e4wy78f1x1 https://t.co/8w1yjarp9S
June 09, 2021
@PoulNissen @AarhusUni Many congratulations! So well deserved.
June 08, 2021
Many congratulations to Dr. Katalin Karikó for the 2022 Vilcek Prize for pioneering vaccine research - she modified RNA to suppress its immunogenicity and expand its life time: https://t.co/0asXiaWPgY
June 08, 2021
Save the date: NEXT GENERATION BIOPHYSICS SYMPOSIUM 2021 Wednesday 29th September 2021 MRC Laboratory of Molecular Biology, Cambridge, UK https://t.co/oXlOVU9Mjg https://t.co/c1cmMq2Fdx
June 08, 2021
Looking forward to the annual molecular biology conference organized by PhD researchers at Göttingen. https://t.co/OzvwEWj21h
June 06, 2021
The new public art gallery #kunsthaus göttingen has opened! First impressions here: https://t.co/5cHNB5fSZ5 https://t.co/DTCB2xDQhM
June 05, 2021
@ABaerbock Bitte setzen sie sich für die Widerspruchsregelung ein
June 03, 2021
Our high-resolution structures of human PIC and Mediator-PIC complexes are published. We define conformational changes underlying DNA opening and suggest how Mediator activates the TFIIH kinase CDK7. https://t.co/yvpUqOZt3m https://t.co/sV4fqSNbOE https://t.co/5amgLXnopW
May 28, 2021
Chromatin remodelers use 'rulers' to set nucleosome array spacing and phasing! Glad we could contribute to this interesting work by @EOberbeckmann @KorberLab https://t.co/4AVaET8Wl4 https://t.co/FbaxA74Mv9
May 24, 2021
@OdedRechavi I recommend Magellan also, if you are interested here a short summary: https://t.co/CtXuGPo9uu
May 21, 2021
@crc_1064 Congratulations to my former colleagues in Munich!
May 21, 2021
Little is known about the biogenesis & nuclear import of RNA polymerases. We now report the structure of the import factor RPAP2 bound to Pol II. It shows RPAP2 must be displaced before transcription can start. Congratulations @isaac_fianu et al.! https://t.co/nZ7vdQsU4U https://t.co/N7QxMAcCzF
May 19, 2021
@canardbruno @nathanpsmad @SFV_France @UnivOuverte @HuetSylvestre Je suis d‘accord, il ne faut pas répéter les erreurs du passé (SARS-COV1)
May 19, 2021
@YuanHe_NWU Congratulation Yuan, so well deserved!
May 18, 2021
So much looking forward to the Mechanisms of Eukaryotic Transcription Meeting on August 31 - September 3, 2022, very unfortunately only virtual. Thanks to great colleagues Mike Levine, Jane Mellor and @NogalesLab for organizing! https://t.co/Rk44G2RYVZ
May 12, 2021
#COVID19 drug candidate #molnupiravir is incorporated by #SARSCoV2 polymerase into RNA and directs misincorporation of G or A when used as template. Structural basis of #antiviral-induced coronavirus mutagenesis. Great collaboration with @HoebartnerLab! https://t.co/8w1yjarp9S https://t.co/VgIiyRArCL
May 11, 2021
When U2 snRNP function is impaired, Pol II accumulates in the promoter proximal region and RNA synthesis activity ceases. It will be exciting to find out how cotranscriptional spliceosome assembly stimulates transcription. https://t.co/66l7SRO87o https://t.co/2bHvK80wGt
May 10, 2021
Many congratulations to @Sveta_Dodonova who will start her new lab @embl in fall! We will miss her! See Svetlana‘s new website here: https://t.co/XDK7Cgjtdd See her pioneering paper here: https://t.co/ypkUInxsGu https://t.co/tfDc3yN6Yp
May 09, 2021
50 years ago, Manfred Eigen founded our institute at Göttingen. https://t.co/0s6jXyl7f4
May 09, 2021
@pisaniferry Toujours pour l‘Europe
May 05, 2021
@neubadah Same here. Just for coronavirus papers it is different: Do everything at once.
May 03, 2021
In this paper we show with purified proteins that the Cdk8 module impairs Mediator binding to the PIC. Cdk8 kinase activity facilitates Mediator dissociation from the Cdk8 module and its binding to the PIC for transcription initiation. Led by @sarakosman. https://t.co/A5Y9eqyclZ https://t.co/b6CX4cv7UC
April 28, 2021
Congratulations to Katja Lidschreiber who will take on the position of coordinator of the new coronavirus research network COFONI. We thank her for the great work and wish her all the best for the future! https://t.co/SsbQnhRy61 https://t.co/sWxsiazW62
April 27, 2021
@BJ_Greber Peer review may not be perfect but it is the best available system to ensure scientific quality. It generally works well. The occasional outliers confirm the rule. Attempts by some journals to make peer review more transparent can avoid issues. Review for journals you publish in.
April 27, 2021
Promoter opening goes along with detachment of TFIIH from the core PIC, predicted to stop DNA translocation and enable RNA chain initiation. Great work of @S_Schilb @shintoez @vasan06 @c_dienemann Free access: PIC: https://t.co/And8iJFovs Mediator-PIC: https://t.co/OaFfresEhu https://t.co/ZM3DUvCHov
April 26, 2021
We present structures of (Mediator)-Pol II pre-initiation complexes at high resolution. Feels great to arrive at a detailed understanding, incl. conformational changes in TFIIH translocase XPB during DNA opening. PIC: https://t.co/yvpUqOZt3m Mediator-PIC: https://t.co/sV4fqSNbOE https://t.co/W5QhtynAo3
April 24, 2021
Celebrating the 50th anniversary of the Protein Data Bank @buildmodels @PDBeurope with 1000 structures of #coronavirus #SARSCoV2: https://t.co/yv1Zrkdm5u https://t.co/zoL3hXgtLY
April 19, 2021
The Warburg lecture on ‚RNA polymerases and the #COVID19 pandemic‘ is now available on the @GBM_eV website: https://t.co/jpF6R72sBS https://t.co/YhZgEY0wOX
April 16, 2021
In contrast to #Remdesivir, #Molnupiravir is orally available. It now shows promise in #COVID19 outpatients. Such #antivirals targeting #coronavirus #SARS-CoV2 polymerase likely must be given early during infection. May become useful prophylactically. https://t.co/TTK4mKZX3a
April 12, 2021
We show how the chromatin remodeller Chd1 and the histone chaperone FACT help RNA polymerase II to pass through a nucleosome. Pol II transcribes into & partially unwraps the nucleosome, enabling Chd1 & FACT to bind. Congrats @LucasFarnung! Free download: https://t.co/RQG5h5EYej https://t.co/hwVgK6U4Fp
April 05, 2021
This study by @davidwtaylorjr and Kenneth Johnson is highly consistent with our study of the molecular mechanism of #remdesivir induced stalling of #coronavirus #SARSCoV2 polymerase due to a translocation barrier: https://t.co/vv2LjM4kjT https://t.co/91hszAkYo9
April 04, 2021
@judithmwhite When was this?
April 01, 2021
@JTrittin @ramin_y @uniGoettingen @faznet @MpStephanWeil @CDUNds Göttingen spielt zudem in der Coronaforschung eine wichtige Rolle @ViolaPriesemann @snpoehlm @CramerLab
March 29, 2021
TT-seq combines short, non-perturbing 4SU labeling with RNA fragmentation to: -detect short-lived eRNA -estimate RNA synthesis & txn initiation rates -monitor txn responses -map putative enhancer landscapes -analyze enhancer cooperation Original method: https://t.co/YIbJre1fxh
March 27, 2021
Enhancers may cooperate synergistically to determine cell fate. Synergistic enhancers are defined by eRNA synthesis, depend on cell-specific TFs and differ form occupancy-defined superenhancers. Great collaboration with Graf & Söding labs. Finally out: https://t.co/en8ctYctzz https://t.co/Zwwd4R3YSo
March 24, 2021
The polymerase of #coronavirus #SARSCoV2 can adopt an alternative structure: an antiparallel dimer with only one nsp8 that may bind only one nsp13. We speculate the dimer facilitates template switching and synthesis of subgenomic viral #RNA. Manuscript: https://t.co/RiGv5eeOYr https://t.co/Vilj3ig98b
March 23, 2021
Congratulations to Alexander Rotsch for obtaining one of the prestigious Boehringer Ingelheim Fellowships! https://t.co/Zz0IRGs0yL
March 14, 2021
High conservation of the yeast (left) and human (right) Mediator-PIC assembly. TFIIH kinase also resides in similar location in yeast complex but was omitted due to mobility. Yeast: https://t.co/8ySgkDnhq5 Human: https://t.co/SXTsLBVYlN https://t.co/xMqBgxCPKh
March 13, 2021
Following 20 years of work on Mediator we share our human Mediator-PIC structure. Mediator hook reaches the TFIIH kinase active center. Great team @vasan06 @S_Schilb @shintoez. Note related work by @YuanHe_NWU @TjianDarzacq. Submitted version of Jan 25: https://t.co/SXTsLBVYlN https://t.co/vAdDSak4Nb
March 08, 2021
Our new paper suggests that co-transcriptional spliceosome assembly triggers efficient release of paused RNA polymerase II for active transcription. Great contribution of first authors @LCaizzi and @SaraMM_4 to #womansday2021! Paper: https://t.co/gEjvLpMN1g https://t.co/pwxMT4bs85
March 07, 2021
We began to collect our structural movies here. We will also upload more talks and other videos of interest. https://t.co/QIGDOK7bz0 via @YouTube
March 04, 2021
Nuclear condensation of NELF: Summary of our collaborative paper with the Sawarkar lab. @rawatravans @MarcBoehning https://t.co/28WZQ3NdFt
March 02, 2021
How chemotherapy works: Great advances in understanding cisplatin since we described in 2007 how this anticancer drug initiates DNA repair. https://t.co/8hgTDVJwrF
March 02, 2021
Registration is now open for the IGBMC-FMI Graduate Student Symposium taking place online April 26-29, 2021. Program includes Cell Biology, Structural Biology, Neurobiology and Epigenetics. @IGBMC @FMIscience @eucor https://t.co/0iOWORMN8q
February 28, 2021
Soon 750 million doses of #vaccine may be produced p.a. at the medieval town of Marburg where immunology pioneer Emil von Behring had used money from the 1901 Nobel Prize to fight diphtheria and tetanus. https://t.co/KZh1GQ7JU9
February 28, 2021
BioNTech founders receive the Order of Merit of the Federal Republic of Germany, many congratulations! https://t.co/3zChpbPs5a
February 26, 2021
Looking forward to speak about “RNA polymerases and #COVID19” at the award event @GBM_eV together with virologist @c_drosten from @ChariteBerlin on March 26. Registration: https://t.co/dpOAVhWoPC https://t.co/5vi5dZCL4S
February 24, 2021
@willida25 @CWolberger @WomenScienceRFS https://t.co/L35xbqDN7s
February 24, 2021
Very grateful to @ERC_Research for funding that also facilitated our work on the #coronavirus polymerase. Thanks to @CORDIS_EU for highlighting our results obtained together with @HoebartnerLab on antiviral drug effectiveness and #Remdesivir: https://t.co/ZVU7T3Ygbq https://t.co/xaGU6PtnkN
February 24, 2021
Looking forward to speak tomorrow at the International Young Scientists Conference on Molecular and Cell Biology organized by young scientists in Warsaw @IIMCB_Poland. Program: https://t.co/uBozI2Povv Website: https://t.co/FHt8UTMI3n https://t.co/njloAltBUE
February 23, 2021
After seven exciting years we have to say good-bye to @LucasFarnung. We thank him for all his great contributions @mpi_bpc and wish him all the best as starting assistant professor @HarvardCellBio @harvardmed. https://t.co/5DvKqYEwfH https://t.co/ruqKMDS1I8
February 22, 2021
Looking forward to speak at the Helmholtz Drug Discovery Conference 2021 that takes place on March 25-26. Free registration: https://t.co/esFK0Cn36Y https://t.co/zCUFNuThrb
February 21, 2021
@alena_buyx Ein großartiger Erfolg, der auf Jahrzehnten von Forschung beruht.
February 20, 2021
TT‐seq maps thousands of eRNA-producing enhancers in human cancer cell lines, providing ~40,000 putative enhancer-promoter pairs, many at cancer‐associated genes. https://t.co/u5n4HxNZE1
February 18, 2021
Great Harnack Lecture by @francesarnold yesterday on enzyme evolution, referring also to the founder of our institute, Manfred Eigen. @mpi_bpc @maxplanckpress https://t.co/x7gp5QVbVa
February 16, 2021
From our work with the Sawarkar lab we propose that stress-induced NELF condensates are nuclear counterparts of cytosolic stress granules. These two condensates may drive the coordinated downregulation of transcription and translation in cells. https://t.co/BF617f0the
February 13, 2021
Deutsche Zusammenfassung unserer Studien zur #Coronavirus Replikation und deren (unvollständige) Inhibition durch das #COVID19 Medikament #Remdesivir https://t.co/vfiwLYQGOk https://t.co/8EoFHgyeuP
February 13, 2021
In 1988, Paul Sigler suggested the CTD binds transcription activators: https://t.co/YmSt9zHSHk Now we see that CTD shortening delays transcription activation... https://t.co/tmRbQpftsc ...and this may be due to CTD-dependent Pol II clustering at genes: https://t.co/429nhCSFwZ https://t.co/aSbDWwfVy4
February 09, 2021
Deadline approaching: apply now to join our PhD program for Genome Science @IMPRS_GS https://t.co/pJXX0OarIp https://t.co/c6iy2ysuv8
February 08, 2021
Now online: Shortening the #CTD of Pol II impairs enhancer transcription and gene activation: https://t.co/tmRbQpftsc This supports a model that CTD is important for Pol II recruitment to active genes by condensation: https://t.co/429nhCSFwZ Grateful to @DarzacqClaire @XDarzacq https://t.co/iwZ7nUp2Kr
February 07, 2021
Wonderful documentary about the visit of star chansonnière Barbara at Göttingen in 1964 and its role in German-French reconciliation. Even if you do not speak German or French, you can feel the famous „Göttingen spirit“. https://t.co/vxdKxCHpkM
February 05, 2021
Nuclear condensation of transcription factor NELF drives downregulation of genes upon stress. Great collaboration of Marc Boehning @mpibpc with @rawatravans and Ritwick Sawarkar @mpi_ie @MRC_TU Now online: https://t.co/UT1q4ao1Hh https://t.co/tuqB7Pxr4f
February 04, 2021
Multi-particle #CryoEM refinement by @DTegunov applied to tomographic data from @Liang_Xue_ in Julia Mahamid's lab @embl enabled us to see an antibiotic bound to its ribosome target inside a bacterial cell. Great collaborative work now published: https://t.co/hdFIjIZD90 https://t.co/yXWeQNeVeF
February 02, 2021
Looking forward to start off the Non-coding Genome Course tomorrow at Institut Curie, Paris. https://t.co/X4RFkH9I0y https://t.co/c7igWtlK0L
February 01, 2021
@PavelTomancak @CEITEC_Brno Great, many congratulations, Pavel!
February 01, 2021
Very grateful to obtain the Hector Science Award. Made possible by many highly dedicated coworkers and the support by mentors, colleagues and collaborators! @mpi_bpc @maxplanckpress @uniGoettingen @GeneCenter_LMU @LMU_Muenchen https://t.co/sgeVvnFnNL https://t.co/G4QfpGjram
January 28, 2021
Congratulations @DTegunov for passing the PhD defense! Outstanding thesis describing Warp and M software for #CryoEM data processing. https://t.co/5vZzAcOFJe https://t.co/d3qCRmhQyi https://t.co/LU6Rs1IWB3
January 27, 2021
Welcome to Göttingen, Metin Tolan! https://t.co/SY877otpS3
January 26, 2021
It is a great honor to receive the Jeantet Prize 2021. Very grateful to past & present coworkers for their contributions over the last two decades. Hoping we can soon get vaccinated and celebrate. @maxplanckpress @mpibpc @LouisJeantetFDN @uniGoettingen https://t.co/vkodhGD284
January 19, 2021
Welcome to Göttingen, @SLorenzLab ! https://t.co/Xa3kP3AEt2
January 16, 2021
Great summary of our findings on the remdesivir mechanism by Prisca Straub from @BR24 @BR_Wissen (German). https://t.co/MMoUq90REj
January 15, 2021
Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters. Glad we could contribute to this work by @MYCGyvers https://t.co/36Ju1ArVq7
January 15, 2021
What does "co-transcriptional splicing" mean? Our model implies that spliceosome assembly is truly co-transcriptional, i.e. functionally dependent on active Pol II. The ensuing catalytic steps of splicing may be Pol II-independent, although they can occur on nascent RNA. https://t.co/PsLmKRGp2k
January 14, 2021
Pol II directly binds U1 snRNP: We propose a 'growing intron loop' model for co-transcriptional splicing. Great collaboration with R. Lührmann @mpi_bpc. Now online: https://t.co/jSxeoOxaQx https://t.co/agPksPLhUt
January 13, 2021
Here is the press release for our remdesivir paper, great collaboration with @HoebartnerLab: https://t.co/2npg4jLrBo https://t.co/oLXkt7cyQe
January 12, 2021
#Remdesivir does NOT block #coronavirus polymerase. It imparis RNA translocation and causes an elongation barrier that is overcome at high substrate concentrations. Our paper presenting the mechanism of remdesivir action is now online: https://t.co/vv2LjM4kjT #SARSCoV2 #COVID19 https://t.co/Y5OROcde0G
January 06, 2021
@Alexis_Verger Cest frai
January 04, 2021
We stand on the shoulders of giants: 50 years ago, visionary scientists agreed to collect all macromolecular structures in a database, the PDB, which also set standards for structure quality and formed the basis of numerous innovations in biomedicine, chapeau! https://t.co/bm4BjocNA1
January 01, 2021
Now published: Integrator is a genome-wide attenuator of non-productive transcription. Great collaboration with @torbenheick. Note conceptual similarity to yeast transcriptome surveillance by Nrd1: https://t.co/o3b8FGc7BN https://t.co/kEh7YgWOYY
December 31, 2020
As 2020 ends - many thanks to all coworkers, alumni, collaborators, colleagues and friends! https://t.co/0UqU2eUmdd
December 29, 2020
mRNA vaccine is an amazing success, based on basic molecular biology, incl.: -Discovery mRNA 1961 -Genetic code & translation -Codon optimization -Phage pol IVT -RNA modification & stability -Structure-based protein engineering 2017 https://t.co/81A4MD5wdK
December 16, 2020
Small-molecule inhibitors of human mitochondrial DNA transcription. Happy we could contribute to this great work by the labs of Claes Gustafsson & Nils-Göran Larsson! @mitopinionated @hauke_hillen https://t.co/M8Sa0herUe
December 11, 2020
Many congratulations to our colleague Asifa Akhtar for receiving the Leibniz Prize 2021! https://t.co/4AwxgeHGnk
December 10, 2020
Thanks to our secret santa @KJArmache for joining today‘s zoom Christmas party! https://t.co/ac1i29nzXx
December 07, 2020
Congratulations to Ruth Ley for obtaining the Otto Bayer Award 2020! Congratulations to Julia Mahamid, Josep Cornella, Nikolai Franzmeier and Marinka Zitnik for obtaining the Early Excellence in Science Awards 2020! @CornellaLab @nfranzme @marinkazitnik https://t.co/850w2NHMYT
December 03, 2020
SAVE THE DATE: Dec 7-11, 2020 Online Workshop "Mechanisms of gene transcription and its regulation" - emphasis on mechanisms and covering transcription systems from viruses to human. Much looking forward to meet close colleagues! Program: https://t.co/HamuepVnJD @LandickLab https://t.co/AiL1BAt1gg
December 02, 2020
The talk by Ayelet Shachar on ‚Shifting borders in the time of #COVID19‘ is now online. https://t.co/AnZhPP5ci0
December 01, 2020
Our new manuscript sugggests how Chd1 and FACT mediate Pol II transcription through a nucleosome. Pol II partially unwraps DNA, activates Chd1 translocase and recruits FACT histone chaperone. Masterpiece by @LucasFarnung with M. Ochmann, M. Engeholm. https://t.co/byUdnAUp0i https://t.co/QB2IxoxOYv
November 30, 2020
Today‘s nearly unbelievable breakthrough in structure prediction should help us obtain missing building blocks for large complexes. ‘It will change everything’: DeepMind’s AI makes gigantic leap in solving protein structures https://t.co/rT9gI8VoZN
November 22, 2020
@ABaerbock Wichtiger Schritt, sich der Gentechnik zu öffnen! Für Medizin, Ernährung und Umwelt.
November 20, 2020
Today we had to say good-bye to Anna (Ania) Sawicka who leaves to take a biotech job in Wroclaw and will be much missed. Stay tuned for Ania's forthcoming paper on the role of the CTD in transcription activation. https://t.co/xJVHG2RQnH
November 18, 2020
@AsifaAkhtar1 @nature Congratulations Asifa!
November 18, 2020
Looking forward to the CCP-EM symposium on the structural biology of #SARSCoV2 and methods development starting today. @ccp_em @EMDB_EMPIAR @wellcometrust https://t.co/5lXaJHycLt
November 12, 2020
@carninci @ewanbirney Great opportunity! Best of success!
November 09, 2020
@AndreaMusacchi1 @YouTube Many congratulations again, Andrea!
November 09, 2020
@JoergLab I must admit that I was hopeful but also skeptical. Let’s hope for the best.
November 07, 2020
A good day for the global scientific community. https://t.co/dbGWKwK8PX
November 07, 2020
@LenaRogl @KamalaHarris So great
November 07, 2020
@mbeisen So great
November 07, 2020
@ewanbirney @jcbarret So great
November 07, 2020
@ArndtLab @jengoefried So great
November 06, 2020
@markschies @HumboldtUni @bbaw_de @ECChronoi @degruyter_TRS Mein Gefühl ist: wir sehen nur noch chronos und kairos wurde vergessen. Dabei werden wir uns später nur an kairos erinnern.
November 06, 2020
Welcome to the new members of our Genome Science graduate program! Including Aiturgan @zhnbkv_ and Florian @FKabinger in our laboratory. https://t.co/ruT8JPdiIL
November 05, 2020
This year's Genome Science lecture series starts tomorrow, Friday at 4.15 pm. @IMPRS_GS https://t.co/8PJLvEou7f
November 01, 2020
As we enter a second (partial) lockdown tomorrow it is so good to know to have such talented, cooperative and resilient coworkers. https://t.co/7xHTJ0PJyl
October 31, 2020
Looking forward to speaking at MIT Biology Colloquium Series on Tuesday Nov 03 at 4 pm EST. Hosted by postdocs. @MITBiology @anafiszbein https://t.co/85eqPAEkTP https://t.co/WbuaLsSEFJ
October 30, 2020
Science communicator and influencer @maithi_nk on basic science @Literaturherbst Göttingen tonight. https://t.co/Ymhzw7V2Qu
October 29, 2020
Solving the remdesivir mechanism was possible in a great collaboration with @HoebartnerLab @Uni_WUE. They synthesized RNA with remdesivir at defined positions. We used their RNA to trap the remdesivir-stalled state of the #SARSCoV2 polymerase by #cryoEM. https://t.co/q7Fgblhm3m https://t.co/VZddeDKz2u
October 29, 2020
We show how the #COVID19 drug #remdesivir inhibits #coronavirus replication: Remdesivir stalls the viral polymerase by posing a translocation barrier, retaining the RNA 3'-end in the substrate-binding site, and hindering RNA proofreading. Preprint: https://t.co/q7Fgblhm3m https://t.co/exN3d51KYk
October 28, 2020
These events are now accessible with your "ON AIR" ticket: Ayelet Shachar: The shifting border (English) https://t.co/cTdIp468UT Jutta Allmendinger: Vertrauen (German) https://t.co/1RheWZyO3A Jörg Hacker: Pandemien (German) https://t.co/DPiYYV6dEN https://t.co/ikOwTP9Ymf
October 27, 2020
@mpi_bpc @maxplanckpress So great
October 26, 2020
@Karl_Lauterbach Danke für diese guten Worte. Eine schreckliche Nachricht und ein enormer Verlust auch für uns Göttinger.
October 24, 2020
@PlantEvolution I was also totally taken by it
October 23, 2020
Congratulations to Jutta Allmendinger for obtaining this year‘ science communications medal! https://t.co/X8E2roFqRR
October 22, 2020
Two simple steps to join the literature festival events. Some in English. Starting tomorrow Friday 7 pm with Jutta Allmendinger @JA_Allmendinger https://t.co/3uxFzUE3kD
October 22, 2020
This year’s lab retreat took place at home and featured great talks by @5_Baldi, @dhnisz, @bulutkarslioglu, Markus Wahl and Jan-Philipp Juncker. Great variety from structure to condensates to cell transitions. https://t.co/WHQbbwRHtj
October 20, 2020
Our RNA polymerase II-U1 snRNP structure elucidates co-transcriptional splicing. It suggest a nascent RNA loop on the Pol II surface enables efficient splice site scanning. Fabulous work by Suyang Zhang in collaboration with the Lührmann lab. Manuscript: https://t.co/jr9y6IbZUX https://t.co/eKHAUoEWsn
October 17, 2020
Some thoughts on where our research field may be heading. From a discussion at the Keystone Meeting on Gene Regulation earlier this year. https://t.co/uR6PpKeb9f https://t.co/24qnLHlVV5
October 17, 2020
She wants to encourage young people to become scientists: “It’s curiosity and passion!” - star photographer Herlinde Kölbl at the opening event of her exhibition ‘Fascination of science’ at Paulinerkirche Göttingen @Literaturherbst @mpi_bpc https://t.co/oK09zHZMRX
October 16, 2020
@Helmholtz_HZI @helmholtz_de Toll, dass das HZI Emmanuelle Charpentier nach Deutschland geholt hatte!
October 16, 2020
@SchindelinL @KiskerLab @RVZ_Wuerzburg @Uni_WUE Really great!
October 16, 2020
@JA_Allmendinger Es freut mich, dass sie jetzt auf Twitter sind aber noch mehr, dass Sie uns bald in Göttingen zum Literaturherbst besuchen!
October 14, 2020
Save the date and keep fingers crossed that we can meet in person. https://t.co/WtxZSnXdax
October 13, 2020
Looking forward to this workshop on the noncoding genome in Paris. https://t.co/zTYel3h0na https://t.co/TWZpMzVluu
October 12, 2020
@patrick_pausch Yes. Absolutely. But most EM structures rely on fitting prior X-ray structures still.
October 09, 2020
Our review containing all RNA polymerase II structures is now freely available online: https://t.co/qpBpD5K51u https://t.co/vEEgjB7Gjl
October 07, 2020
Remembering the Paul-Ehrlich-Prize 2016 to Emmanuelle and Jennifer with former lab member Claus Kuhn as junior awardee. @doudna_lab https://t.co/2PFd9yEXlp
October 07, 2020
And here comes the next generation: a very warm welcome to our new group leader at the institute, Marieke Oudelaar! Her group will study genome organization and regulation. @MariekeOudelaar Website: https://t.co/lfP1FwEQoD https://t.co/L8OXkq11qV
October 07, 2020
Many congratulations to our Max Planck colleague Emmanuelle Charpentier and Berkeley structural biologist Jennifer Doudna for the Nobel Prize 2020! So great! @doudna_lab @maxplanckpress https://t.co/hRB51WTFK1
October 06, 2020
Many congratulations to our Max Planck colleague Reinhard Genzel for obtaining the Nobel Prize in physics. Fabulous! https://t.co/WPjNRlYjpd
October 02, 2020
Very excited to meet legendary photographer Herlinde Kölbl in Berlin tonight. Her recent project ‚fascinating science’ features 60 scientists from around the globe. @bbaw_de https://t.co/6b1CBjq86v
October 01, 2020
Our new ‘Eigen Lounge’ is now ready for coffee and round table discussions. It commemorates the founder of our institute, Nobel laureate Manfred Eigen. https://t.co/fQlq1CPpUT
October 01, 2020
Hauke Hillen is starting as a tenure-track professor today at the University of Göttingen & UMG. Congratulations and all the best to the new lab! @hauke_hillen @uniGoettingen @mpi_bpc https://t.co/D0EE1Wjx1z
September 29, 2020
@TheresiaBauer @unikonstanz @maxplanckpress @martinwikelski Das freut mich als gebürtigen Schwaben besonders! Ich erinnere mich an die interessanten Diskussionen zur Gründung dieses großartigen Instituts. Einzigartige Technologie @martinwikelski
September 23, 2020
Great opportunity for ambitious junior researchers! Please do not hesitate to contact your favorite Max Planck Institute for advice. https://t.co/c90PeXKz62
September 20, 2020
@AmyShaubMaddox The loneliness of the leader
September 16, 2020
The literature festival @Literaturherbst is starting soon. Looking forward to host (7 pm): Jutta Allmendinger (sociology), October 23 Jörg Hacker (pandemics), October 25 Ayelet Shachar (borders & migration), October 27 One online ticket for all events: https://t.co/xcWzwpRIzD https://t.co/1PXiSQ7S9x
September 14, 2020
@AprilPawluk @MolecularCell @CellReports @CellPressNews Best of success! To best serve the community I recommend to take clear decisions.
September 13, 2020
@FuturiumD Viel Erfolg!
September 13, 2020
@SteffenKrach @ChariteBerlin Ja, ein großer Glücksfall für Berlin!
September 11, 2020
A 15-minute summary of the current state of our work on #SARSCoV2 polymerase and its inhibition by #remdesivir #COVID19 https://t.co/FrwM9QuiP7
September 11, 2020
Save the date: #COVID19 #SARSCoV2 Cold Spring Harbor Asia Virtual Conference on Nov 2-4, 2020. https://t.co/aEpT42BaP5
September 09, 2020
@KouMurayama @uni_tue @AvHStiftung Welcome
September 08, 2020
Now published: our method detecting newly synthesized RNA isoforms and monitoring isoform metabolism in cells (nano-ID). Great team effort coordinated by Björn Schwalb @birdumbrella. #nanopore @nanopore @NanoporePapers Paper: https://t.co/zvdKCZ2zQz https://t.co/DRbE3sqx1p
September 07, 2020
@maithi_nk Many congratulations!
September 03, 2020
Many congratulations to our colleagues at the institute, Juliane and Stefan! https://t.co/W0KiCVJUmW
August 28, 2020
@KellyTHD_Nguyen This is so sad, Chris had organized a great party on the occasion of Kiyoshi’s 70th birthday last year which had to be canceled due to his illness...this is so sad.
August 27, 2020
@Pol2Runner Yes in the nucleosome
August 27, 2020
Half a year later: first real space Cramer lab group meeting with distancing. https://t.co/eI9GImYK2y
August 26, 2020
Looking forward to this student-organized symposium on October 7-8, 2020. #Eureka2020 https://t.co/lkBk6PAR1B
August 24, 2020
Join the 17th Horizons in Molecular Biology Conference on September 14-17, 2020! Great speaker line-up. https://t.co/fVyS04OcSW https://t.co/s51xWYCMal
August 22, 2020
Here we review all ~200 available Pol II complex structures and summarize how these elucidated transcription initiation, promoter-proximal pausing and elongation, and the navigation of nucleosomes and DNA lesions. https://t.co/YkGP5BZeWP
August 20, 2020
Free download of the benchmark paper on Rosalind Franklin and the advent of molecular biology: https://t.co/2ojECGGsLl #franklin100 #WomenInStem #DNA https://t.co/nAqRYMTkT7
August 19, 2020
Save the date: The 86th Harden Conference - Machines on Genes is rescheduled for 9-13 May 2021 and takes place in Alicante, Spain. https://t.co/VQJdUkXCMS https://t.co/LvpMKR9AuO
August 19, 2020
Registration is now open for our local coronavirus research webinar symposium on September 3, 2020: https://t.co/PIhVyMF6nP https://t.co/9l3pjDW9vr
August 17, 2020
Defining permissive epigenomes that enable cell reprogramming by various transcriptional regulators. Happy we could contribute to this study by the Schöler lab. #stemcells https://t.co/ddBRdoD3GW
August 06, 2020
The final version of our paper reporting the #SARSCoV2 polymerase-RNA structure is now available. A basis for investigating #coronavirus replication-blocking antivirals such as #Remdesivir. https://t.co/vYBLxdAiik https://t.co/c8Q7oyhtBG
August 02, 2020
Integrator is a genome-wide attenuator of non-productive transcription. Combining factor depletion, TT-seq and bioinformatics. Great collaboration with @torbenheick. Manuscript: https://t.co/3Zxz8SFRti https://t.co/1UjkZLyNtk
July 30, 2020
Now online: visualizing the central dogma inside cells! Glad we could contribute to this marvelous work on the expressome by the labs of Julia Mahamid and Juri Rappsilber @RappsilberLab @FJ_OReilly @Liang_Xue_ @DTegunov @JorgStulke @embl Paper: https://t.co/ti5akkIEFI https://t.co/Y8XhaWJF1S
July 30, 2020
Thanks to the editors at Cell for prioritizing this important historical topic. #Franklin100 https://t.co/suFR9x56CR
July 30, 2020
@CWolberger Thank you for your great thread on this topic, Cynthia!
July 29, 2020
@g1_guillermo @cryoEM_Papers @MolecularCell @CRISPR_News @sofos112 @SQunxin @NNFCPR @UCPH_health Really great, many congratulations!
July 29, 2020
Rosalind Franklin provided the key data for deriving the double helix structure of DNA. She also pioneered studies of viruses and RNA. This benchmark essay celebrates the 100th anniversary of Franklin’s birth and the advent of molecular biology. https://t.co/reVcNSRyer
July 28, 2020
Join the seminars by Lucas Farnung and Hitoshi Kurumizaka tomorrow. https://t.co/zHPDjAMgj5
July 26, 2020
@CWolberger I agree; there will be a paper on this in Cell on Wednesday.
July 24, 2020
@giacomo_cavalli Thanks Giacomo; there will be a paper in Cell on her next week. Best
July 22, 2020
@TriggerLoop @researchsquare Maybe a biogenesis/assembly factor?
July 22, 2020
@afisch82 @TriggerLoop @JosefowiczLab @sjosefowicz Really great, many congratulations!
July 17, 2020
Patrick‘s overview seminar given at Dana Farber/Harvard Cancer Center is now available online: https://t.co/wqEM1kibS0 https://t.co/46mOKTdnEW
July 14, 2020
Join Patrick’s talk online at Dana Farber/Harvard Cancer Center @df_hcc on Thursday at 12 noon Boston time. https://t.co/ReuMwII1dH https://t.co/DBQJVaRrs1
July 03, 2020
Dimitry Tegunov‘s multiparticle cryo-EM refinement software ‚M’ is now available for download. https://t.co/c72Qsg9QXZ
July 01, 2020
Very much looking forward to work with our new leadership! @AsifaAkhtar1 https://t.co/oR7eNm5n8F
June 17, 2020
Evidence that CDK12 maintains an active transcription elongation complex by retaining the PAF complex. Happy we could collaborate with the lab of Shona Murphy. https://t.co/2RA2kAfIpc
June 16, 2020
@STOPlabPl Good luck!
June 16, 2020
Our new paper on the nucleosome-CHD4 chromatin remodeler structure is online. CHD4 is involved in gene repression and does not detach terminal DNA, in contrast to Chd1, which works in active transcription. We also map disease mutations. @LucasFarnung https://t.co/uxpEJQyEPv https://t.co/BsU9J4SV1c
June 16, 2020
Save the dates: program for our next seminar series is out. Much looking forward to host our colleagues @Beck_Laboratory, @HymanLab, @KukulskiWanda, Edward Lemke, Frank Uhlmann, @NVastenhouw & @tinekelenstra. https://t.co/fnNOq392Nu https://t.co/RTnryRTsza
June 16, 2020
Like other enzymes, Pol II is regulated allosterically by proteins that influence active site structure & dynamics from a distance. First seen for the initiation factor TFIIB, now for the elongation factor RTF1. TFIIB: https://t.co/NksFDlWsqN RTF1: https://t.co/rAXISgAZ7O https://t.co/Z7FhNnZeNy
June 15, 2020
Pol II speed is enhanced by PAF subunit RTF1. Our new paper shows allosteric activation via the famous bridge helix. @seyvos @LucasFarnung Publication: https://t.co/L8D6mYZr6N
June 10, 2020
@billhansson @maxplanckpress Thank you so much for everything, Bill!
June 09, 2020
Isaac Fianu passed his PhD defense today, many congratulations! https://t.co/GOt5WtSvH7
June 08, 2020
CTCF-dependent genome topology is not strictly required for a functional cell-fate conversion but facilitates a rapid and efficient response to an external stimulus. Happy we could contribute to this important study of the Graf lab @CRGenomica. https://t.co/tqfqhj8HoB
June 06, 2020
@brodriguezsci Best to ask Dimitry...
June 06, 2020
"In agreement with a model of condensate-driven transcription initiation, large clusters of hypophosphorylated Pol II rapidly disassembled upon Mediator degradation." Happy we could contribute to this great collaboration with Martin Jaeger and Georg Winter. https://t.co/9hk3s9CNhW
June 06, 2020
Dimitry Tegunov's software 'M' enables multi-particle refinement and higher resolution in #cryoEM. Applied to tomography data from @Liang_Xue_ & Julia Mahamid @embl, M reveals ribosome-antibiotic complex at 3.7 Å in cells. @DTegunov @c_dienemann Preprint https://t.co/d3qCRmzrWS https://t.co/4SjBSY4rbW
May 26, 2020
We welcome our new colleague at the institute, Claus Ropers! https://t.co/4YEpnHnEs9
May 26, 2020
Welcome at our institute, Stefan! https://t.co/vNyK7kZJK0
May 25, 2020
Happy to join and serve on the Scientific Advisory Board of the Gulbenkian Institute in Lisbon, Portugal. https://t.co/0hyK0SEeQF
May 21, 2020
Our paper describing the #coronavirus RNA polymerase structure is online. The nsp8 extensions contact RNA far away from the active site, apparently enabling processive replication of the very long #SARSCoV2 genome. Publication: https://t.co/go28YxOvaO PR: https://t.co/bT7ig1Oyjc https://t.co/9qHUsPvDru
May 18, 2020
After nearly two months in home office we carefully return to the lab. Here are 56 thoughts of the day that accumulated: https://t.co/HasfvfbCp3 https://t.co/5GCJzBFcoD
May 16, 2020
@IbrahimCisse_ @MIT_Physics @Cisse_lab Great many congratulations
May 15, 2020
Happy to share the original cryoEM data used to solve our #coronavirus #SARSCoV2 polymerase-RNA complex structure. https://t.co/NF2RBnWS4P
May 13, 2020
Explore #coronavirus replication in 3D. Our structural data for the RNA-dependent RNA polymerase of #SARSCoV2 in replication mode are now online: PDB: https://t.co/A1NQ6HZTDE EMDB: https://t.co/ccvuMIKC9R Preprint: https://t.co/KWD2bgPWGb PR: https://t.co/bT7ig1Oyjc https://t.co/eKazemLzog
May 08, 2020
@Alexis_Verger @MED_COMPLEX Hey very nice overview! Is it really already two decades? Well yes we got older...
May 06, 2020
@lkreidberg Welcome and all the best! Patrick Cramer
April 30, 2020
Here is a simple animation of #coronavirus replication: NTPs enter from the right and are added to the growing RNA copy (red) of the #SARSCoV2 RNA genome (blue) by the viral polymerase. #COVID19 Preprint: https://t.co/KWD2bgPWGb Press release: https://t.co/bT7ig1Oyjc https://t.co/2n7roSm6MS
April 28, 2020
Watching #coronavirus replication! #SARSCoV2 polymerase-RNA structure: basis to study potential #COVID19 drug #Remdesivir Team @hauke_hillen @KokicGoran @LucasFarnung @c_dienemann @DTegunov @mpi_bpc @maxplanckpress Preprint https://t.co/KWD2bgPWGb PR https://t.co/bT7ig1Oyjc https://t.co/sNHHRcx7qe
April 27, 2020
Very honored to be elected as a foreign member of the National Academy @theNASciences. Many thanks to my colleagues and friends in the US! https://t.co/cXTwLGufDp https://t.co/CsWJaQhAyu
April 22, 2020
Our structures of nucleosome-bound Yamanaka factor Sox2 and Sox11 elucidate how pioneer factors invade chromatin for differentiation and development. https://t.co/ypkUInxsGu https://t.co/m21gRRsUxB
April 20, 2020
Many congratulations to Lucas Farnung who accepted an offer from @Harvard and will start his lab at Boston in January 2021! https://t.co/fLpQaTbISo
April 18, 2020
@EsbinMeagan Many thanks indeed, really very kind of you! Please send my regards to Tij!
April 17, 2020
25 days in home office started with 25 thoughts of the day. Here they are: https://t.co/cdqvRFsNR2 https://t.co/SxCJ4MkxPk
April 17, 2020
@FMIscience @SchubelerLab Congratulations and best wishes, Dirk!
April 01, 2020
Increasing the sensitivity of crosslinking-mass spectrometry with a new peptide database. Glad we could contribute to this important technical development of the lab of Henning Urlaub. Publication: https://t.co/agjmRzlTxi https://t.co/zi96Zj4T3H
March 31, 2020
We are supported again by an Advanced Grant of the European Research Council @ERC_Research. With these funds we will extend our research towards the mechanisms of chromatin transcription. Thanks to all coworkers who made this possible. https://t.co/JuPRL0gqg4 https://t.co/kuCHrWV8Mm
March 25, 2020
We start each day in home office with an encouraging philosophic quote in our Email inbox. Here is today's: “What does not engage our feelings does not long engage our thoughts either.” Lou Andreas-Salomé, Russian-German author 1861 St. Petersburg – 1937 Göttingen https://t.co/uBU8Og62We
March 23, 2020
First virtual Cramer lab meeting. Science continues mainly online. Take care of yourselves during these times. https://t.co/pkSSFdaLHT
March 11, 2020
Our structure of the SWI/SNF chromatin remodelling complex RSC is now published! https://t.co/i1cGE7b8Cr
March 08, 2020
Great event this weekend @uniGoettingen @thegoecampus @ForumWissenGoe celebrating the international women's day #IWD2020 featuring Margot Kaessmann, Naima Diesner, Nivedita Mani, Jacqueline Amirfallah, Katrin Adt. https://t.co/tRYnNTHkjA
March 01, 2020
Chromatin remodelers contain ‘ruler’ elements that set nucleosome array spacing. Happy we could contribute to this collaboration between the labs of Philipp Korber, @hopfnerlab and @PetersonLab. Preprint: https://t.co/H770mZdp2O
March 01, 2020
The expressome structure we obtained in 2017 in vitro after stalling RNA polymerase (collaboration with Landick lab) is now shown to be adopted in vivo as an inactive state when transcription is blocked. Link to our 2017 in vitro expressome paper: https://t.co/GOAUCJtws1 https://t.co/zaWPQZkdqB
February 29, 2020
Visualizing the central dogma in cells! The labs of Julia Mahamid @embl and @RappsilberLab present the in situ structure of the transcribing-translating expressome. Glad we could contribute. @DTegunov @WimJHH @JorgStulke Preprint: https://t.co/o2LQ8OGccr https://t.co/zhY9PEyaM1
February 28, 2020
@FRobertLab @JeronimoCelia Absolutely great
February 27, 2020
Register for the "Gene transcription in yeast” Conference that takes place June 13-18, 2020 in Sant Feliu de Guixols, Spain: https://t.co/afkBJuTlfd https://t.co/03KRZN3WlL
February 26, 2020
Welcome to our new colleage Jochen Rink! @rinklab @mpi_bpc https://t.co/j25SijXy2c
February 26, 2020
Today we celebrated our recent successes with a lunch at a nearby village! Nice walk passing two medieval churches... https://t.co/A9Fs6bhqB2
February 13, 2020
Save the date: @ASBMB Meeting on Transcriptional Regulation: Chromatin and RNA Polymerase II takes place Oct 1-5, 2020 in Snowbird, Utah. https://t.co/SSzLLWTDHy https://t.co/GVgwjyBTS3
February 10, 2020
It is an honor to accept the Otto Warburg Medal on behalf of past and present members of the laboratory. The Warburg Lecture will take place on April 3, 2020 during the GBM symposium on “The world of RNAs” https://t.co/aedOREHqqj https://t.co/IzP4TKopSw https://t.co/RZvzPxiweV
February 05, 2020
Shintaro Aibara obtained a Marie Curie Fellowship of the European Union, many congratulations! https://t.co/PB18hXFqhW
January 28, 2020
The Hilldale Lecture given by Patrick at the University of Wisconsin in Madison last week is now available at YouTube: https://t.co/ofQMzPXRZd @UWBiochem https://t.co/UScwPXP9vf
January 27, 2020
Around 450 participants at the joint Keystone meetings on Gene Regulation and Cancer Epigenetics! Follow us: #KSgene https://t.co/BJMR67L7Vr
January 22, 2020
Our structure of the chromatin-modifying coactivator SAGA elucidates early events before transcription pre-initiation complex formation. Note related work from the Schultz lab published back-to-back. @mpibpc @igbmc https://t.co/iCx29FDwyt https://t.co/XoPYpknrPo
January 14, 2020
Patrick Cramer will give the Weisbach Memorial Lecture @RockefellerUniv this Friday at 4 pm https://t.co/CKQi3BCEN1 https://t.co/FHrag0tOKU
January 06, 2020
Save the date for the key European transcription/chromatin conference of the year, taking place 29 August to 01 September in Heidelberg. And: Happy New Year from the Cramer lab! https://t.co/Zep9E7ltWj
January 04, 2020
@Lab_Journal Was sind die neuen Forschungsfelder in den Life Sciences, die in Deutschland zu wenig präsent sind?
December 19, 2019
Special Christmas reading on the efforts, rewards and drawbacks of exploration: 500 years after the first circumnavigation of the world... https://t.co/qZmNgI4Jf2 https://t.co/5yz0TBRrff
December 18, 2019
This video explains our work - with a focus on cryo-electron microscopy (English subtitles). Thanks to the Schering Foundation for enabling this. https://t.co/fiYY4A6FV8
December 17, 2019
Join the symposium to celebrate the 25th anniversary of the Eppendorf Award on June 25, 2020 in Heidelberg. Free registration: https://t.co/LmO3TpYQtc
December 12, 2019
First structures of viral multisubunit RNA polymerase: complete, core, transcribing, & capping complexes of Vaccinia show how such viruses make capped mRNA. Great collaboration with the lab of Utz Fischer in Würzburg! Free download: https://t.co/jTAj7hJp8n https://t.co/u3i6i8ERQf https://t.co/69NlmGgC65
December 09, 2019
Recognition of histone H3 trimethylated at K36 by a conserved reader domain: Our new paper reports the structure of the modified nucleosome-PWWP complex and multivalent binding to the methylated histone tail and both DNA gyres. @NatureSMB https://t.co/yGZ3jYcMKU https://t.co/ixqyTC5KWP
December 08, 2019
Our colleague Reinhard Jahn startet as new president of the University of Göttingen. Hear his inauguration speech (in German): https://t.co/4Xdfu5ylvC
December 06, 2019
Hosting Hans Schöler as our Christmas Speaker 2019! https://t.co/5WfSr9BVub
November 29, 2019
Felix Wagner passed his PhD defense today, many congratulations! Cryo-EM structure of the SWI/SNF chromatin remodelling complex RSC bound to a nucleosome. https://t.co/BiIfxZV1aF https://t.co/TRVDPGCbbU
November 20, 2019
Marc Böhning passed his PhD defense, many congratulations! Pol II clustering driven by CTD phase separation. Great collaboration with @mz_science and @TjianDarzacq https://t.co/429nhCSFwZ https://t.co/S65GyGXAH2
November 05, 2019
Free download of the historic perspective on 50 years of eukaryotic transcription research. Summarizes major advances in the field and provides exemplary and key original references. https://t.co/EFGQ2KNTZK
October 28, 2019
Congratulations to Edith Heard, Director General of EMBL, who received the Hansen Family Award today for her pioneering work in epigenetics. @Bayer @emblebi @embl @heard_lab https://t.co/gS3hX54VJZ
October 22, 2019
The first scientific travel report: discussing Georg Forster‘s ‚voyage around the world‘ from 1777 with historian Frank Vorpahl @ZDF @Literaturherbst @thegoecampus @ForumWissenGoe https://t.co/bqwj2qEhqk
October 20, 2019
Rewriting human history: Our Max Planck colleague Johannes Krause explains how DNA sequencing revolutionizes anthropology. „We are all migrants!“ Today at @Literaturherbst @mpi_bpc @thegoecampus https://t.co/4f62RvbyfI
October 19, 2019
Amazing start of our public science talks at the literature festival 2019, from now on every evening for the next ten days. https://t.co/h1PqssJY3P https://t.co/HhpeNSmQha
October 15, 2019
Our structure of the SWI/SNF chromatin remodeling complex RSC bound to a nucleosome and exit DNA provides insights into formation of nucleosome-depleted, transcriptionally active promoters: https://t.co/BiIfxZV1aF Note forthcoming related work by @Nogaleslab and Yuan He's lab https://t.co/ROjnTE5EDi
October 14, 2019
Abstract deadline approaching for @KeystoneSymp meeting "Gene Regulation: From Mechanisms to Disease" in #Keystone. https://t.co/1Qfx1uzwsq. #KSgene https://t.co/yImAgztJn3
October 14, 2019
This month‘s issue of @Lab_Journal features a ‚journal club’ commentary on our work on how Pol II pausing influences transcription initiation. https://t.co/bUlirm1JDs https://t.co/sfMoqGKTot
October 13, 2019
Patrick will give lectures in Rotterdam, Utrecht, and Eindhoven on the next three days. Thanks to the Netherlands Society for Biochemistry and Molecular Biology for the invitation! https://t.co/3wUNKxu6NN https://t.co/emIPAsrKmY
October 09, 2019
Sunny Liu defended her PhD thesis, many congratulations! https://t.co/61wURpBvJ9
October 07, 2019
Now published: Real-time cryo-EM data pre-processing with Warp, by Dimitry @DTegunov. Warp corrects and denoises images, automatically picks particles, and generates output for RELION. @cryoEM_Papers #CryoEM Paper: https://t.co/5vZzAcx4RG Software: https://t.co/f6Zv2EDFl0 https://t.co/3tnVt8ctIF
October 04, 2019
Vasan Rengachari received a postdoctoral fellowship of the Engelhorn Foundation, many congratulations and best of success! https://t.co/6NIdf7c0Q8
October 01, 2019
A growing global network! Cramer lab reunion with diverse talks by alumni, full of advice: “Stay excited”, “follow your dreams”, “bring empathy to the table!” Thank you for sharing your experiences. @KJArmache @VanniniLab https://t.co/WnEguvYS0j
October 01, 2019
Congratulations to alumnus Alessandro Vannini, now Director of Structural Biology at Human Technopole in Milano! https://t.co/VXrnTkM3B2
September 30, 2019
Kiyoshi Nagai was a wonderful colleague, always interested in the latest science, always positive, and following an important long-term goal, which he achieved only recently; he will be sadly missed. https://t.co/m04d19DCPD
September 30, 2019
This year‘s lab retreat at Ringberg Castle starts off with a great talk by Julia Mahamid @embl https://t.co/9Hgj3mw9Ri
September 27, 2019
Many thanks to the Schering Foundation for organizing a great event in Berlin to celebrate the Ernst Schering Prize 2019. Thanks to all past and current members of the laboratory for their outstanding contributions that made this possible! @ScheringStiftg @mpi_bpc @thegoecampus https://t.co/RfUvvkAoPS
September 26, 2019
Today, Lucas Farnung received the Karl Lohmann Prize for his PhD research. He solved the first high-resolution structure of a complete chromatin remodeller, Chd1, bound to a nucleosome! https://t.co/ysa2ees7tR @mpi_bpc @LucasFarnung @thegoecampus @goetageblatt https://t.co/25TZmFCjkr
September 26, 2019
Thank you and all the best for the future! President of the University of Göttingen Ulrike Beisiegel is stepping down. @uniGoettingen @thegoecampus @mpi_bpc https://t.co/H95s2QXeBX
September 20, 2019
Apply and join the Max Planck Society as a Research Group Leader, great start-up packages offered! https://t.co/3fnaUX4Tex
September 11, 2019
Exciting line-up of speakers at the EMBO|EMBL Symposium ‘Multiomics to Mechanism’. Follow us at #eesomics https://t.co/RlKZ0JMCA7 https://t.co/tAFHFvYamJ
September 02, 2019
The Schering Prize 2019 recognizes past and current members of our laboratory and their fabulous research! Thanks also to everyone who supported us. Video (German): https://t.co/pjlfvtKcYy Press release (English): https://t.co/wrQot0EGcM https://t.co/cWTu9x06aM
September 02, 2019
Reunion with alumni Karim-Jean Armache (NYU), Alan Cheung (UCL), Andreas Mayer (MPI Berlin) and Seychelle Vos (MIT) at Cold Spring Harbor during #MOET2019. https://t.co/DIPZa4eu3p
August 31, 2019
Many thanks to all participants for the great positive energy at the CSHL anniversary transcription meeting #MOET2019 and for all contributions! Please save the date for the next meeting: Aug 31-Sep 04, 2021! https://t.co/bBd8wzqFiN
August 28, 2019
Now online: this review summarizes the state of the eukaryotic transcription field and describes the dynamic interplay between nuclear condensates and Pol II complexes that together organize transcription. #moet2019 https://t.co/sKh35wZuhk
August 28, 2019
Magnificent opening lecture by Bob Roeder, founding father of the eukaryotic transcription field, summarizes five decades of frontier research. #moet2019 https://t.co/nlGpP1HN0E
August 27, 2019
Celebrating 50 years of eukaryotic RNA polymerases at the Cold Spring Harbor meeting on Mechanisms of Eukaryotic Transcription, starting tonight. Follow us at #moet2019 https://t.co/Yo71UzoI3S
August 22, 2019
Last chance to register for this year‘s Horizons conference, organized by PhD students at our institute, great speakers! https://t.co/14FEG6hpCN
August 20, 2019
The exciting program for this year's literature festival is out. Covering politics, fiction, society, science, history. Mainly in German. Tickets are sold out quickly... Popular science talks: https://t.co/h1PqssJY3P Full program: https://t.co/leomP0xtnQ https://t.co/33QvnU0vVX
August 09, 2019
We show directly that transcription activation often involves a decrease in Pol II pause duration. Multiomics reveals this requires CDK9 and increases the productive initiation frequency. In contrast to promoters, enhancers are generally not pause-limited. https://t.co/RcJGLGHTTC https://t.co/cZRrlCZXo0
July 26, 2019
Saying thank you and good-bye to Seychelle Vos and wishing her all the best as Assistant Professor at MIT! https://t.co/lCG39hqhWP
July 17, 2019
Our new paper with the Sandberg lab describes NASC-seq, which monitors RNA synthesis (rather than RNA levels) in single cells and can be used to follow differentiation events. Publication: https://t.co/sSAj4entmH Protocol: https://t.co/KgiKn46ksM https://t.co/woeCL8rgfG
July 16, 2019
Sara Osman passed her PhD defense today, many congratulations! https://t.co/lJuxu5me0m
July 12, 2019
Katharina, Saskia and Goran formally graduated today, congratulations and all the best for the future! https://t.co/OqSlCMgDr4
July 08, 2019
We welcome our new colleague Ruben Fernandez Busnadiego, a master in cryo-electron tomography, at the Göttingen science campus! @uniGoettingen @thegoecampus @mpi_bpc https://t.co/BUakap2wEJ
June 30, 2019
Our structure of the human TFIIH-XPA-DNA complex is published. The results explain how TFIIH switches from a transcription factor to a DNA repair factor, and represent the first step in a mechanistic analysis of nucleotide excision repair. https://t.co/nsfd62mCGK https://t.co/CFzBZ6AZkj
June 26, 2019
Today Sandra Schilbach received the Otto Hahn Medal for her great work on solving the structure of the Pol II pre-initiation complex with TFIIH and core Mediator. Great location in Hamburg. Congratulations! https://t.co/B4rXsJF2h1
June 25, 2019
Our structure of the human chromatin remodeller CHD4 in complex with the nucleosome deviates from the previous Chd1 structure, consistent with a role of this factor in gene repression rather than active transcription. Manuscript: https://t.co/32xVF45gYT https://t.co/gpqYJdZyBr
June 24, 2019
Our new seminar program is out. Looking forward to host again fine colleagues at Göttingen. Save the dates! https://t.co/eAHFEwCcoi
June 13, 2019
TT-seq is widely applicable to monitor RNA synthesis and enhancer dynamics in human cells. We now provide a detailed lab protocol and bioinformatic analysis pipeline: Experimental: https://t.co/V4wa1tUkIf Analysis: https://t.co/GNsCK42lyG https://t.co/XHgxmczCY4
June 12, 2019
@NogalesLab @EMBO Great many congratulations
June 07, 2019
Our paper on splicing kinetics is out. In a collaboration with the @gagneurlab we provide rates for 5‘ and 3‘ RNA cleavage in human cells. https://t.co/klYpq9BdCu
June 01, 2019
Our structure of the super elongation complex (SEC) subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization in SEC formation. SEC functions in release of Pol II from promoter-proximal pausing. Manuscript: https://t.co/jLb9uZRsZ7 https://t.co/qA6F0XlmAJ
May 28, 2019
Our new paper presents transcriptome maps of 30 general RNA degradation factors, revealing their occupancy and possibly functional relationships. Great collaboration with the lab of Johannes Soeding! Manuscript: https://t.co/BhZb4H7FUE https://t.co/4UXDbg4q8k
May 24, 2019
Many congratulations to our colleague Brenda Schulman who received the Jung Prize for Medicine yesterday in Hamburg! https://t.co/MYJTGaEPQR
May 07, 2019
Our high-resolution structure of human TFIIH with DNA & XPA represents an intermediate of DNA nucleotide excision repair (NER). Watch how the transcription factor (@NogalesLab) switches to repair mode, engaging DNA with both ATPases, XPB & XPD. Manuscript: https://t.co/aWsVlPn8Zj https://t.co/A6xHe6zsQe
May 07, 2019
Many congratulations to our very successful postdoc Seychelle Vos who will open her lab at MIT this fall! https://t.co/5hnRrWVi9i
May 06, 2019
Congratulations to Katharina Hofmann and Saskia Gressel who both passed their PhD defense today! Great talks on functional genomics. All the best for the future! https://t.co/YQ4Mkf2u3e
April 27, 2019
@LugerLab @NatureSMB Really great many congratulations!
April 26, 2019
Our new paper elucidates human splicing kinetics. TT-seq and modeling reveal how splicing rates depend on Pol II elongation and RNA sequences. Great collaboration with Gagneur lab! https://t.co/kxrVJyATpX @eLife @RNASociety @RNApreprints @RNA_seq @gagneurlab @LCaizzi @leonhard https://t.co/f4tFR79Pkw
April 23, 2019
Save the date: Keystone meeting on "Gene Regulation: From Mechanisms to Disease" and a parallel meeting on Cancer Epigenetics take place January 26-30, 2020 in Keystone, Colorado. Please RT! Flyer: https://t.co/uFaseSDQYv Information: https://t.co/YRxQcU4xpM https://t.co/AXmEhCPGe9
April 10, 2019
Goran Kokic passed his PhD exam. Impressive work on TFIIH in DNA repair. Many congratulations! https://t.co/pIHWN40TQB
April 08, 2019
We report a method to directly sequence newly synthesized, individual mRNA transcripts in human cells. Reveals metabolism of RNA splice variants/isoforms. https://t.co/caANJDnPRg https://t.co/P3uYAy1QeR
April 04, 2019
The new childcare facility at our institute just opened. Many thanks to all who helped! https://t.co/ZVQKghN5fs
March 27, 2019
MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. Thanks to Elmar Wolf for the great collaboration. https://t.co/OeCE59w9jL https://t.co/cyPsNu5WuG
March 26, 2019
Fine collaboration with the Anikin lab now resulted in our paper on posttranscriptional gene regulation in mitochondria: https://t.co/VIGtGodbD2 https://t.co/WNqHaJKM29
March 26, 2019
Please RT: Cold Spring Harbor Meeting on Mechanisms of Eukaryotic Transcription takes place August 27-31, 2019. Celebrating 50 years of eukaryotic RNA polymerases! https://t.co/y4DQ8j6bhX https://t.co/CxbH0UP3aL
March 26, 2019
Save the date: EMBO | EMBL Symposium: Multiomics to Mechanisms - Challenges in Data Integration, 11-13 September 2019 at Heidelberg. https://t.co/RlKZ0Jv1bx https://t.co/wS545u4gMo
March 11, 2019
Deadline approaching for applications to become a Group Leader in our Lise Meitner program for young female researchers! https://t.co/ny8QUtavkO
March 05, 2019
We thank Randy Schekman for his outstanding service as first editor-in-chief of eLife and look forward to working with Michael Eisen to support the leading OA journal! https://t.co/rddwwVPUte
February 27, 2019
@UhlenhautLab Great, congratulations!
February 26, 2019
Congratulations to our friends at @BIMSB_MDC @MDC_Berlin on the opening of their beautiful new building in Berlin by chancellor Merkel today! https://t.co/YTUbpv5kc8
February 21, 2019
Save the date: conference on chromatin dynamics in Bad Nauheim near Frankfurt, September 9-11, 2019 https://t.co/ZzCpesQAP1
February 21, 2019
Many congratulations to our close colleague Herbert Jäckle! https://t.co/FymBSQ0EDY
December 27, 2018
Great collaboration with the Heard lab. TT-seq monitors X chromosome gene inactivation. Glad we could contribute to this interesting multiomics temporal analysis. @heard_lab https://t.co/yRR7xBxbge
December 22, 2018
Our structure of the transcribing RNA polymerase II-nucleosome complex is now published and available online https://t.co/nF7c1P1eWo https://t.co/qCWs4c3O5t
December 18, 2018
NASC-seq monitors gene activity in single cells by detecting new mRNA. Great collaboration with the Sandberg lab. Manuscript: https://t.co/q8r4EjQq7G https://t.co/Msaldzs5RM
December 14, 2018
@Beck_Laboratory Great to have you as a colleague! All the best
December 14, 2018
Hosting Asifa Akhtar from @mpi_ie as our Christmas speaker https://t.co/779umFJtuw
December 11, 2018
Suyang Zhang arrived from Cambridge @MRC_LMB and obtained an EMBO postdoctoral fellowship, many congratulations! https://t.co/Hkn3S4aJpd
December 06, 2018
And another Leibnizprize for our colleague Ayelet Shachar at the neighboring Max Planck institute, many congratulations! https://t.co/T32Mn9oeC3
December 06, 2018
Many congratulations to our colleague at the institute, Melina Schuh, for being awarded the Leibnizpreis, the highest distinction in Germany! https://t.co/SnsDMM0xIf
November 30, 2018
CPF and APT are required to form 3'-ends on coding and non-coding genes, respectively. Our paper resulting from a collaboration with @lapassmore is now online. https://t.co/tQ0ib7ol0f https://t.co/jPNlPzdI9u
November 21, 2018
We mourn the passing of Aaron Klug, a giant of molecular biology, who reported the first structure of tRNA https://t.co/otyrCARGcM
November 21, 2018
Our new structure suggests that DNA opening during transcription initiation involves promoter DNA distortion and closure of the RNA polymerase II clamp https://t.co/Z4brj4UezP https://t.co/49aFKPx3CN
November 20, 2018
Congratulations to former lab member Alan Cheung on becoming an EMBO Young Investigator! https://t.co/pxaF4oywJq
November 14, 2018
Save September 11-13, 2019, for the EMBO|EMBL symposium on ‚Multiomics to mechanism - challenges in data integration‘ https://t.co/syNTFveOq3 https://t.co/39VdY6zKDx
November 08, 2018
Many congratulations to Laleh Haghverdi and Julijana Gjorgjieva for receiving the Engelhorn Research Prize 2018 in Computational Biology! https://t.co/GN7RowCxr9
October 24, 2018
Join us for a symposium in honor of Dirk Eick on November 9 in Munich #transcription #cancer #epigenetics #chromatin https://t.co/EYT118lGTv https://t.co/Qq5HmWAa7d
October 16, 2018
Full house also for the discussion with Manuela Lenzen who presented her book on artificial intelligence and machine learning in the beautiful Paulinerkirche @Literaturherbst @thegoecampus @mpi_bpc https://t.co/zZzDLcnyfE
October 15, 2018
Hosting Germany‘s top energy economist tonight, Claudia Kemfert. Discussing her latest book on how to switch fast to renewable energy and fight climate change. @CKemfert @Literaturherbst https://t.co/Ij7b1BvL0M
October 11, 2018
Tom Steitz is well known for the work on ribosomes, but his lab also paved the way to an understanding of RNA polymerases with seminal papers in the 90s on phage enzymes. A real hero of molecular biology who will be sadly missed. https://t.co/xG2XMCugOR
October 08, 2018
Our structure of the Pol II-nucleosome complex reveals a defined nucleosome orientation and provides the starting point for understanding the mechanisms of chromatin transcription: https://t.co/0H2ZAOEhrV https://t.co/PgcBDZ6rwd
October 07, 2018
Congratulations to Salma Sohrabi-Jahromi for her poster award at the EMBL conference and thanks to the Söding lab for the collaboration on mapping RNA degradation factors on the transcriptome https://t.co/6r8rj6vDjZ
September 27, 2018
Our application with the University of Göttingen and the Medical Center UMG for a large national research cluster on Multiscale Bioimaging was funded, thanks to all who helped us! https://t.co/r32QK0hclf
September 25, 2018
Nucleosome-transcription factor interaction landscape mapped. Thanks to Fangjie Zhu and Jussi Taipale for the great collaboration! https://t.co/R5fAYAd4kd https://t.co/P8CEEXMa0R
September 21, 2018
Distinct multiprotein complexes form the 3'-ends of protein-coding and non-coding RNAs. Great collaboration with Lori Passmore's lab @lapassmore. https://t.co/i7cjzedivZ https://t.co/biOw3d3GSS
September 15, 2018
We contributed to an enjoyable science slam in the old city, featuring scientists from all five Max Planck institutes in Göttingen https://t.co/mWv2LesikZ
September 13, 2018
Tomorrow we celebrate the foundation of the Max Planck Society in Göttingen 70 years ago. Join us for a sciene slam at the local pub: https://t.co/J8eFsdmayT
September 12, 2018
Save the date for next year‘s Cold Spring Harbor Meeting on Mechanisms of Eukaryotic Transcription, August 27-September 01, 2019 https://t.co/y4DQ8j6bhX
September 06, 2018
Our new review on mitochondrial transcription includes the first molecular movie of the mitochondrial transcription cycle. Publication: https://t.co/ggkieyWkHb Movie: https://t.co/PGgLDQ4Bfz https://t.co/SGC8NoFHCH
September 05, 2018
Save the date: GRC conference on mechanisms of microbial transcription takes place July 28 to August 2, 2019 in Maine https://t.co/cKH1ZXXQK2
September 05, 2018
Investigate the switch from paused to activated transcription complex in 3D! Our new Pol II complex structures and density maps are available for download: https://t.co/p4vK1h28ed https://t.co/WP5WNcBTW7 https://t.co/VF1WYGR8CA https://t.co/1zaO0GcCUO https://t.co/Ff2SPNfUWX
September 02, 2018
@ProfJohnsen Really? When? This is sad for us.
August 31, 2018
Registration for the Structural Dynamics VIB Conference in Bruxelles ends in one week https://t.co/L94bI7vdWr https://t.co/IKItdeqZGx
August 23, 2018
Thanks to our colleague Karen Adelman for summarizing our recent findings on Pol II pausing and release and putting them into context: News and Views: https://t.co/LGxCbq6ZTU
August 22, 2018
Molecular basis of transcription regulation: our new papers elucidate promoter-proximal RNA polymerase II pausing and elongation activation by human DSIF, NELF, PAF, SPT6. https://t.co/0HXbgvZ1aL https://t.co/bWwGzcuXEr https://t.co/aJ4y5zyXRr
August 20, 2018
Our paper on RNA polymerase II clustering through CTD phase separation is now online. Thanks to the Zweckstetter and @XDarzacq labs for the great collaboration! https://t.co/429nhCSFwZ https://t.co/UzdWlDJguO
August 15, 2018
Congratulations to our Max Planck colleagues: Global animal tracking from space! https://t.co/nUaQ9HA51h
August 15, 2018
@animaltracking @Astro_Alex @AniMove @unikonstanz @maxplanckpress @icouzin @UWICER @MP_Innovation Congratulations on the great Tagesschau Beitrag!!
August 08, 2018
RNA velocity predicts the fate of single cells. Glad we could contribute to an exciting collaboration of the Linnarsson and Kharchenko labs @slinnarsson @KharchenkoLab https://t.co/3lYCBAL3dw
August 01, 2018
Many congratulations to Peter Scholze, our new colleage at the Max Planck Institute in Bonn, for obtaining the Fields Medal, the ‚Nobel Prize‘ in Mathematics https://t.co/T4cbNMIVwz https://t.co/x9qNrct9am
July 04, 2018
Council congratulates EMBL Barcelona for getting successfully started! https://t.co/xBolhBo3Gu
July 04, 2018
The Klenk Symposium on Epigenetics will take place October 4-6, 2018 in Cologne. https://t.co/lPVXMq0nup
June 24, 2018
The scandinavian #cryoEM symposium will take place in Copenhagen October 8-9, 2018 https://t.co/B0M74sDrgR
June 22, 2018
Save May 20-22, 2019 for the DNA damage response mechanisms conference in Madrid https://t.co/Cz1aeK6RkC
June 14, 2018
'Warp' software by Dmitry Tegunov closes the gap between the electron microscope and 3D density reconstruction. See our manuscript and user guide for automated real-time cryo-EM data pre-processing and particle picking https://t.co/h0vimmogWJ https://t.co/JWgrel6Jgd #cryoEM #Warp https://t.co/bv72UDxIPB
June 09, 2018
Vienna RNA biology meeting will take place October 17-19, see https://t.co/JvbahsZbhh https://t.co/bUMYtQ1eRR
June 07, 2018
Our next seminar series program is out, please save the dates and join. https://t.co/OVclPOY1x7
June 07, 2018
Many congratulations to our colleague at the institute, Jens Frahm, on winning the European Inventor Award! Do not miss their incredible movies made with real time MRI! https://t.co/UTx1087rR0
June 04, 2018
@benoitbruneau @Gene_Regulation TT-Seq we think
May 25, 2018
Our new review provides a movie of RNA polymerase I transcription that can be used for teaching purposes https://t.co/IBHN33r1LK https://t.co/cZGrd2F7pb
May 23, 2018
On the shoulders of giants: celebrating the ‚founding fathers’ of our field, Bob Roeder, Bill Rutter, and Pierre Chambon in Paris on the occasion of the 50th anniversary of the discovery of the eukaryotic RNA polymerases https://t.co/zDbIlwIObE
May 16, 2018
Many congratulations to Melina and our neighbors! https://t.co/ttWk4sUxcw
May 16, 2018
@SchuhLab @EMBO Great! Many congratulations!
May 10, 2018
@R_H_Ebright PDB took very long; we sent it to many colleagues by mail
May 09, 2018
Our structures of transcription initiation complexes with TFIIH and Mediator are now available for download: https://t.co/PyKXvc5Qvw https://t.co/H3Iy6lUMXQ https://t.co/mkq36fB76C https://t.co/zBuJf8fLLR
May 08, 2018
The RNA polymerase II CTD phase separates in vitro and governs polymerase clustering in vivo. Thanks to the Zweckstetter and @XDarzacq laboratories for this collaboration. Read the manuscript at https://t.co/vbfBgbeekf https://t.co/Gatul5SkaY
May 08, 2018
Great student-organized molecular biology meeting at Göttingen in fall https://t.co/nlqsxWPVG2
May 01, 2018
We are deeply saddened by the untimely passing of our great colleague Elisa Izaurralde, RNA biochemist at MPI Tübingen. https://t.co/dlPFpwDLdM
April 28, 2018
Join us on May 9 at 1 pm for the talk of Kelly Nguyen who just published the marvelous structure of human telomerase #cryoEM #RNA https://t.co/YgL5bMSj49
April 14, 2018
Marching for free and open science! https://t.co/uLp1NErfWD
April 12, 2018
Join the 2nd March for Science in Göttingen on April 14! https://t.co/s4ts3qa7oa
April 11, 2018
Patrick Cramer presents Kjeldgaard lecture in Aarhus, Denmark https://t.co/coKzWNsRKc https://t.co/1lLCHD7GbA
April 09, 2018
Christian Dienemann passed his PhD exam, many congratulations! https://t.co/Fyp1sY6QJI
April 03, 2018
Save December 5-7 for this year's epigenetics meeting in Freiburg https://t.co/kdnn53Lr6h
March 28, 2018
Congratulations to Hauke Hillen for obtaining this year's PhD Award of the German Society for Biochemistry and Molecular Biology for elucidating mitochondrial transcription! https://t.co/JIt0vs8Vca https://t.co/x5uvxnzdpy https://t.co/ZQgzFI1TW3
March 18, 2018
Our new cryo-EM structure shows why the mushroom toxin amanitin binds 3000-times better to mammalian RNA polymerase II than to the yeast enzyme https://t.co/G8ZC1jjQql https://t.co/HjMeJ5rILH
March 16, 2018
RNA polymerases 50 years on: save May 22 for the symposium in Paris https://t.co/yRYydGi1aD
February 19, 2018
Sandra Schilbach passed her PhD exam, presenting the pre-initiation complex structure, many congratulations! https://t.co/8ySgkDnhq5 https://t.co/x6vNm6zTvE
February 14, 2018
Congratulations to former lab member Clemens Plaschka who will start as a group leader at IMP Vienna soon! https://t.co/2FAyshTyjN https://t.co/uFgIaoRbQv
February 06, 2018
@TheVillaLab Many thanks for organizing this interesting meeting!
January 26, 2018
Congratulations to former lab member Christoph Engel on winning the Early Excellence in Science Award of the Bayer Foundation https://t.co/N73AqwnvUV https://t.co/s5qlOTUBdw
January 18, 2018
Congratulations to Vannini and Müller labs on the Pol III PIC structures!
January 17, 2018
Our Stockholm team moves into the new building ‘Neo’ at Karolinska Institute https://t.co/IDEnBPLNUj https://t.co/uEEgdQ3Oq6
January 16, 2018
Applications for PhD fellowships are invited by our new Max Planck Research School for Genome Science that brings together experimental and computational biologists https://t.co/pJXX0OarIp https://t.co/qEhIexHo4z
January 13, 2018
A good summary of our recent structure of the Chd1 chromatin remodeling factor bound to the nucleosome published in Nature Structural and Molecular Biology by Michaela Smolle https://t.co/QjddNtNJxa https://t.co/rd1daFUUch
January 03, 2018
Congratulations to Youwei Xu who takes on an Assistant Professor position at Shanghai Tech University https://t.co/Lt8DSBwD5w https://t.co/EH0ia3EHx5
December 29, 2017
Our paper with Jussi Taipale’s lab on the interaction landscape of transcription factors and the nucleosome is available https://t.co/lCWUigXIWK
December 21, 2017
Goodbye to Kayo Nozawa who takes a Research Associate position at Waseda University in Tokyo. https://t.co/dlGpakp4dI https://t.co/FgvAEPIl82
December 19, 2017
Christoph Engel starts his research group at Regensburg University in January 2018, funded by the Emmy-Noether-Programme. https://t.co/iUj53Wa7bT
December 18, 2017
Haibo Wang received an EMBO postdoctoral fellowship, congratulations! https://t.co/V3L6Gw8GYi
December 16, 2017
Xiaoguang Xue received an EMBO long-term fellowship, congratulations! https://t.co/a7TyDsHsCW
December 08, 2017
We host Julie Ahringer from Cambridge as our Christmas speaker https://t.co/0wqea2pnP3
December 02, 2017
Good-bye to Carrie Bernecky and all the best to her lab at IST Austria! https://t.co/JmnR57ySzB
November 30, 2017
Congratulations to the Max Delbrück Center in Berlin, it turns 25! #MDC25 https://t.co/Uh5I4Fipjf
November 16, 2017
Cell published our mechanism of transcription initiation in human mitochondria... https://t.co/zqj3shnIO0
November 08, 2017
Our institute hosts Kim Nasmyth for a Bonhoeffer Award Lecture https://t.co/Fuhqerv7po https://t.co/UwnZAAWclG
November 07, 2017
Patrick Cramer gives the Weigle Lecture in Geneva, where early molecular biology was done https://t.co/lJwrBmBTPb https://t.co/Ie5muCrOz2
November 06, 2017
Congratulations to Lucas Farnung and Hauke Hillen for passing their PhD exams! https://t.co/SkIrI70INX
November 04, 2017
From now on, updates on our facebook page will be shared on twitter
November 04, 2017
@nature published our milestone structure of a 46-subunit transcription initiation complex with TFIIH and Mediator https://t.co/3FtHLn0i44 https://t.co/Mj7cRwvIm7
November 04, 2017
From now on, our facebook page updates will be shared on twitter.