Zeitschriftenartikel (312)

201.
Zeitschriftenartikel
Wu, C.-C.; Herzog, F.; Jennebach, S.; Lin, Y.-C.; Pai, C.-Y.; Aebersold, R.; Cramer, P.; Chen, H.-T.: RNA polymerase III subunit architecture and implications for open promoter complex formation. Proceedings of the National Academy of Sciences of the USA 109 (47), S. 19232 - 19237 (2012)
202.
Zeitschriftenartikel
Dümcke, S.; Seizl, M.; Etzold, S.; Pirkl, N.; Martin, D. E.; Cramer, P.; Tresch, A.: One Hand Clapping: detection of condition-specific transcription factor interactions from genome-wide gene activity data. Nucleic Acids Research 40 (18), S. 8883 - 8892 (2012)
203.
Zeitschriftenartikel
Mayer, A.; Heidemann, M.; Lidschreiber, M.; Schreieck, A.; Sun, M.; Hintermair, C.; Kremmer, E.; Eick, D.; Cramer, P.: CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II. Science 336 (6089), S. 1723 - 1725 (2012)
204.
Zeitschriftenartikel
Cheung, A. C. M.; Cramer, P.: A movie of RNA polymerase II transcription. Cell 149 (7), S. 1431 - 1437 (2012)
205.
Zeitschriftenartikel
Niederberger, T.; Etzold, S.; Lidschreiber, M.; Maier, K. C.; Martin, D. E.; Fröhlich, H.; Cramer, P.; Tresch, A.: MC EMiNEM maps the interaction landscape of the Mediator. PLoS Computational Biology 8 (6), e1002568 (2012)
206.
Zeitschriftenartikel
Treutlein, B.; Muschielok, A.; Andrecka, J.; Jawhari, A.; Buchen, C.; Kostrewa, D.; Hög, F.; Cramer, P.; Michaelis, J.: Dynamic architecture of a minimal RNA polymerase II open promoter complex. Molecular Cell 46 (2), S. 136 - 146 (2012)
207.
Zeitschriftenartikel
Walmacq, C.; Cheung, A. C. M.; Kireeva, M. L.; Lubkowska, L.; Ye, C.; Gotte, D.; Strathern, J. N.; Carell, T.; Cramer, P.; Kashlev, M.: Mechanism of translesion transcription by RNA polymerase II and its role in cellular resistance to DNA damage. Molecular Cell 46 (1), S. 18 - 29 (2012)
208.
Zeitschriftenartikel
Sun, M.; Schwalb, B.; Schulz, D.; Pirkl, N.; Etzold, S.; Larivière, L.; Maier, K. C.; Seizl, M.; Tresch, A.; Cramer, P.: Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation. Genome Research 22 (7), S. 1350 - 1359 (2012)
209.
Zeitschriftenartikel
Koschubs, T.; Dengl, S.; Dürr, H.; Kaluza, K.; Georges, G.; Hartl, C.; Jennewein, S.; Lanzendörfer, M.; Auer, J.; Stern, A. et al.; Huang, K.‑.; Packman, K.; Gubler, U.; Kostrewa, D.; Ries, S.; Hansen, S.; Kohnert, U.; Cramer, P.; Mundigl, O.: Allosteric antibody inhibition of human hepsin protease. Biochemical Journal 442 (3), S. 483 - 494 (2012)
210.
Zeitschriftenartikel
Jennebach, S.; Herzog, F.; Aebersold, R.; Cramer, P.: Crosslinking-MS analysis reveals RNA polymerase I domain architecture and basis of rRNA cleavage. Nucleic Acids Research 40 (12), S. 5591 - 5601 (2012)
211.
Zeitschriftenartikel
Wild, T.; Cramer, P.: Biogenesis of multisubunit RNA polymerases. Trends in Biochemical Sciences 37 (3), S. 99 - 105 (2012)
212.
Zeitschriftenartikel
Vannini, A.; Cramer, P.: Conservation between the RNA polymerase I, II, and III transcription initiation machineries. Molecular Cell 45 (4), S. 439 - 446 (2012)
213.
Zeitschriftenartikel
Larivière, L.; Seizl, M.; Cramer, P.: A structural perspective on Mediator function. Current Opinion in Cell Biology 24 (3), S. 305 - 313 (2012)
214.
Zeitschriftenartikel
Mayer, A.; Schreieck, A.; Lidschreiber, M.; Leike, K.; Martin, D. E.; Cramer, P.: The Spt5 C-terminal region recruits yeast 3= RNA cleavage factor I. Molecular and Cellular Biology 32 (7), S. 1321 - 1331 (2012)
215.
Zeitschriftenartikel
Schwalb, B.; Schulz, D.; Sun, M.; Zacher, B.; Dümcke, S.; Martin, D. E.; Cramer, P.; Tresch, A.: Measurement of genome-wide RNA synthesis and decay rates with Dynamic Transcriptome Analysis (DTA). Bioinformatics 28 (6), S. 884 - 885 (2012)
216.
Zeitschriftenartikel
Cheung, A. C. M.; Sainsbury, S.; Cramer, P.: Structural basis of initial RNA polymerase II transcription. EMBO Journal 30 (23), S. 4755 - 4763 (2011)
217.
Zeitschriftenartikel
Seizl, M.; Hartmann, H.; Hoeg, F.; Kurth, F.; Martin, D. E.; Söding, J.; Cramer, P.: A conserved GA element in TATA-less RNA polymerase II promoters. PLoS One 6 (11), e27595 (2011)
218.
Zeitschriftenartikel
Ringel, R.; Sologub, M.; Morozov, Y. I.; Litonin, D.; Cramer, P.; Temiakov, D.: Structure of human mitochondrial RNA polymerase. Nature 478 (7368), S. 269 - 273 (2011)
219.
Zeitschriftenartikel
Blattner, C.; Jennebach, S.; Herzog, F.; Mayer, A.; Cheung, A. C. M.; Witte, G.; Lorenzen, K.; Hopfner, K.-P.; Heck, A. J. R.; Aebersold, R. et al.; Cramer, P.: Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth. Genes and Development 25 (19), S. 2093 - 2105 (2011)
220.
Zeitschriftenartikel
Geiger, S. R.; Böttcher, T.; Sieber, S. A.; Cramer, P.: A conformational switch underlies ClpP protease function. Angewandte Chemie International Edition 50 (25), S. 5749 - 5752 (2011)
221.
Zeitschriftenartikel
Czeko, E.; Seizl, M.; Augsberger, C.; Mielke, T.; Cramer, P.: Iwr1 directs RNA polymerase II nuclear import. Molecular cell 42 (2), S. 261 - 266 (2011)
222.
Zeitschriftenartikel
Müller, M.; Heym, R. G.; Mayer, A.; Kramer, K.; Schmid, M.; Cramer, P.; Urlaub, H.; Jansen, R. P.; Niessing, D.: A cytoplasmic complex mediates specific mRNA recognition and localization in yeast. PLoS Biology 9 (4), e1000611 (2011)
223.
Zeitschriftenartikel
Seizl, M.; Larivière, L.; Pfaffeneder, T.; Wenzeck, L.; Cramer, P.: Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization. Nucleic Acids Research 39 (14), S. 6291 - 6304 (2011)
224.
Zeitschriftenartikel
Vojnic, E.; Mourão, A.; Seizl, M.; Simon, B.; Wenzeck, L.; Larivière, L.; Baumli, S.; Baumgart, K.; Meisterernst, M.; Sattler, M. et al.; Cramer, P.: Structure and VP16 binding of the Mediator Med25 activator interaction domain. Nature Structural and Molecular Biology 18 (4), S. 404 - 409 (2011)
225.
Zeitschriftenartikel
Ruan, W.; Lehmann, E.; Thomm, M.; Kostrewa, D.; Cramer, P.: Evolution of two modes of intrinsic RNA polymerase transcript cleavage. Journal of Biological Chemistry 286 (21), S. 18701 - 18707 (2011)
226.
Zeitschriftenartikel
Cheung, A. C. M.; Cramer, P.: Structural basis of RNA polymerase II backtracking, arrest and reactivation. Nature 471 (7337), S. 249 - 253 (2011)
227.
Zeitschriftenartikel
Martinez‐Rucobo, F. W.; Sainsbury, S.; Cheung, A. C. M.; Cramer, P.: Architecture of the RNA polymerase–Spt4/5 complex and basis of universal transcription processivity. EMBO Journal 30 (7), S. 1302 - 1310 (2011)
228.
Zeitschriftenartikel
Miller, C.; Schwalb, B.; Maier, K.; Schulz, D.; Dümcke, S.; Zacher, B.; Mayer, A.; Sydow, J.; Marcinowski, L.; Dölken, L. et al.; Martin, D. E.; Tresch, A.; Cramer, P.: Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast. Molecular Systems Biology 7, 458 (2011)
229.
Zeitschriftenartikel
Clausing, E.; Mayer, A.; Chanarat, S.; Müller, B.; Germann, S. M.; Cramer, P.; Lisby, M.; Strässer, K.: The transcription elongation factor Bur1-Bur2 interacts with replication protein A and maintains genome stability during replication stress. Journal of Biological Chemistry 285 (53), S. 41665 - 41674 (2010)
230.
Zeitschriftenartikel
Sun, M.; Larivière, L.; Dengl, S.; Mayer, A.; Cramer, P.: A tandem SH2 domain in transcription elongation factor Spt6 binds the phosphorylated RNA polymerase II C-terminal repeat domain (CTD). Journal of Biological Chemistry 285 (53), S. 41597 - 41603 (2010)
231.
Zeitschriftenartikel
Beck, K.; Vannini, A.; Cramer, P.; Lipps, G.: The archaeo-eukaryotic primase of plasmid pRN1 requires a helix bundle domain for faithful primer synthesis. Nucleic Acids Research 38 (19), S. 6707 - 6718 (2010)
232.
Zeitschriftenartikel
Vannini, A.; Ringel, R.; Kusser, A. G.; Berninghausen, O.; Kassavetis, G. A.; Cramer, P.: Molecular basis of RNA polymerase III transcription repression by Maf1. Cell 143 (1), S. 59 - 70 (2010)
233.
Zeitschriftenartikel
Mayer, A.; Lidschreiber, M.; Siebert, M.; Leike, K.; Söding, J.; Cramer, P.: Uniform transitions of the general RNA polymerase II transcription complex. Nature Structural and Molecular Biology 17 (10), S. 1272 - 1278 (2010)
234.
Zeitschriftenartikel
Geiger, S. R.; Lorenzen, K.; Schreieck, A.; Hanecker, P.; Kostrewa, D.; Heck, A. J. R.; Cramer, P.: RNA polymerase I contains a TFIIF-related DNA-binding subcomplex. Molecular Cell 39 (4), S. 583 - 594 (2010)
235.
Zeitschriftenartikel
Cramer, P.: Towards molecular systems biology of gene transcription and regulation. Biological Chemistry 391 (7), S. 731 - 735 (2010)
236.
Zeitschriftenartikel
Hirtreiter, A.; Damsma, G. E.; Cheung, A. C. M.; Klose, D.; Grohmann, D.; Vojnic, E.; Martin, A. C. R.; Cramer, P.; Werner, F.: Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif. Nucleic Acids Research 38 (12), S. 4040 - 4051 (2010)
237.
Zeitschriftenartikel
Chen, Z. A.; Jawhari, A.; Fischer, L.; Buchen, C.; Tahir, S.; Kamenski, T.; Rasmussen, M.; Lariviere, L.; Bukowski‐Wills, J.‐.; Nilges, M. et al.; Cramer, P.; Rappsilber, J.: Architecture of the RNA polymerase II–TFIIF complex revealed by cross‐linking and mass spectrometry. EMBO Journal 29 (4), S. 717 - 726 (2010)
238.
Zeitschriftenartikel
Koschubs, T.; Lorenzen, K.; Baumli, S.; Sandström, S.; Heck, A. J. R.; Cramer, P.: Preparation and topology of the Mediator middle module. Nucleic Acids Research 38 (10), S. 3186 - 3195 (2010)
239.
Zeitschriftenartikel
Sydow, J.F.; Kostrewa, D.; Martin, D.; Cramer, P.: 10 Jahre RNA-Polymerase-Struktur – von Transkription zu Genregulation. BIOspektrum 16 (1), S. 24 - 27 (2010)
240.
Zeitschriftenartikel
Kostrewa, D.; Zeller, M. E.; Armache, K.-J.; Seizl, M.; Leike, K.; Thomm, M.; Cramer, P.: RNA polymerase II–TFIIB structure and mechanism of transcription initiation. Nature 462 (7271), S. 323 - 330 (2009)
241.
Zeitschriftenartikel
Sydow, J. F.; Cramer, P.: RNA polymerase fidelity and transcriptional proofreading. Current Opinion in Structural Biology 19 (6), S. 732 - 739 (2009)
242.
Zeitschriftenartikel
Damsma, G. E.; Cramer, P.: Molecular basis of transcriptional mutagenesis at 8-Oxoguanine. Journal of Biological Chemistry 284 (46), S. 31658 - 31663 (2009)
243.
Zeitschriftenartikel
Dengl, S.; Cramer, P.: Torpedo nuclease Rat1 is insufficient to terminate RNA polymerase II in vitro. The Journal of Biological Chemistry 284 (32), S. 21270 - 21279 (2009)
244.
Zeitschriftenartikel
Andrecka, J.; Treutlein, B.; Arcusa, M. A. I.; Muschielok, A.; Lewis, R.; Cheung, A. C. M.; Cramer, P.; Michaelis, J.: Nano positioning system reveals the course of upstream and nontemplate DNA within the RNA polymerase II elongation complex. Nucleic Acids Research 37 (17), S. 5803 - 5809 (2009)
245.
Zeitschriftenartikel
Sydow, J. F.; Brueckner, F.; Cheung, A. C.M.; Damsma, G. E.; Dengl, S.; Lehmann, E.; Vassylyev, D.; Cramer, P.: Structural basis of transcription: Mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA. Molecular Cell 34 (6), S. 710 - 721 (2009)
246.
Zeitschriftenartikel
Brueckner, F.; Ortiz, J.; Cramer, P.: A movie of the RNA polymerase nucleotide addition cycle. Current Opinion in Structural Biology 19 (3), S. 294 - 299 (2009)
247.
Zeitschriftenartikel
Dengl, S.; Mayer, A.; Sun, M.; Cramer, P.: Structure and in vivo requirement of the yeast Spt6 SH2 domain. Journal of Molecular Biology 389 (1), S. 211 - 225 (2009)
248.
Zeitschriftenartikel
Brueckner, F.; Armache, K. J.; Cheung, A.; Damsma, G. E.; Kettenberger, H.; Lehmann, E.; Sydow, J.; Cramer, P.: Structure–function studies of the RNA polymerase II elongation complex. Acta Crystallographica Section D: Biological Crystallography 65 (2), S. 112 - 120 (2009)
249.
Zeitschriftenartikel
Reich, C.; Zeller, M.; Milkereit, P.; Hausner, W.; Cramer, P.; Tschochner, H.; Thomm, M.: The archaeal RNA polymerase subunit P and the eukaryotic polymerase subunit Rpb12 are interchangeable in vivo and in vitro. Molecular Microbiology 71 (4), S. 989 - 1002 (2009)
250.
Zeitschriftenartikel
Koschubs, T.; Seizl, M.; Larivière, L.; Kurth, F.; Baumli, S.; Martin, D. E.; Cramer, P.: Identification, structure, and functional requirement of the Mediator submodule Med7N/31. The EMBO Journal 28 (1), S. 69 - 80 (2009)
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