Publikationen

202.

Zeitschriftenartikel

Sun, M.; Schwalb, B.; Pirkl, N.; Maier, K. C.; Schenk, A.; Failmezger, H.; Tresch, A.; Cramer, P.: Global analysis of eukaryotic mRNA degradation reveals Xrn1-dependent buffering of transcript levels. Molecular cell 52 (1), S. 52 - 62 (2013)

MPG.PuRe

203.

Zeitschriftenartikel

Schwinghammer, K.; Cheung, A. C. M.; Morozov, Y. I.; Agaronyan, K.; Temiakov, D.; Cramer, P.: Structure of human mitochondrial RNA polymerase elongation complex. Nature Structural and Molecular Biology 20 (11), S. 1298 - 1303 (2013)

MPG.PuRe

204.

Zeitschriftenartikel

Kinkelin, K.; Wozniak, G. G.; Rothbart, S. B.; Lidschreiber, M.; Strahl, B. D.; Cramer, P.: Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proceedings of the National Academy of Sciences of the USA 110 (38), S. 15277 - 15282 (2013)

MPG.PuRe

205.

Zeitschriftenartikel

Larivière, L.; Plaschka, C.; Seizl, M.; Petrotchenko, E. V.; Wenzeck, L.; Borchers, C. H.; Cramer, P.: Model of the Mediator middle module based on protein cross-linking. Nucleic Acids Research 41 (20), S. 9266 - 9273 (2013)

MPG.PuRe

206.

Zeitschriftenartikel

Lidschreiber, M.; Leike, K.; Cramer, P.: Cap completion and C-terminal repeat domain kinase recruitment underlie the initiation-elongation transition of RNA polymerase II. Molecular and cellular biology 33 (19), S. 3805 - 3816 (2013)

MPG.PuRe

207.

Zeitschriftenartikel

Fouqueau, T.; Zeller, M. E.; Cheung, A. C.; Cramer, P.; Thomm, M.: The RNA polymerase trigger loop functions in all three phases of the transcription cycle. Nucleic acids research 41 (14), S. 7048 - 7059 (2013)

MPG.PuRe

208.

Zeitschriftenartikel

Michel, M.; Cramer, P.: Transitions for regulating early transcription. Cell 153 (5), S. 943 - 944 (2013)

MPG.PuRe

209.

Zeitschriftenartikel

Esslinger, S. M.; Schwalb, B.; Helfer, S.; Michalik, K. M.; Witte, H.; Maier, K. C.; Martin, D.; Michalke, B.; Tresch, A.; Cramer, P. et al.; Förstemann, K.: Drosophila miR-277 controls branched-chain amino acid catabolism and affects lifespan. RNA Biology 10 (6), S. 1042 - 1056 (2013)

MPG.PuRe

210.

Zeitschriftenartikel

Bernecky, C.; Cramer, P.: Struggling to let go: A non‐coding RNA directs its own extension and destruction. EMBO Journal 32 (6), S. 771 - 772 (2013)

MPG.PuRe

211.

Zeitschriftenartikel

Sainsbury, S.; Niesser, J.; Cramer, P.: Structure and function of the initially transcribing RNA polymerase II–TFIIB complex. Nature 493 (7432), S. 437 - 440 (2013)

MPG.PuRe

212.

Zeitschriftenartikel

Martinez-Rucobo, F. W.; Cramer, P.: Structural basis of transcription elongation. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1829 (1), S. 9 - 19 (2013)

MPG.PuRe

213.

Zeitschriftenartikel

Larivière, L.; Plaschka, C.; Seizl, M.; Wenzeck, L.; Kurth, F.; Cramer, P.: Structure of the Mediator head module. Nature 492 (7429), S. 448 - 451 (2012)

MPG.PuRe

214.

Zeitschriftenartikel

Miller, C.; Matic, I.; Maier, K. C.; Schwalb, B.; Roether, S.; Strässer, K.; Tresch, A.; Mann, M.; Cramer, P.: Mediator phosphorylation prevents stress response transcription during non-stress conditions. Journal of Biological Chemistry 287 (53), S. 44017 - 44026 (2012)

MPG.PuRe

215.

Zeitschriftenartikel

Wu, C.-C.; Herzog, F.; Jennebach, S.; Lin, Y.-C.; Pai, C.-Y.; Aebersold, R.; Cramer, P.; Chen, H.-T.: RNA polymerase III subunit architecture and implications for open promoter complex formation. Proceedings of the National Academy of Sciences of the USA 109 (47), S. 19232 - 19237 (2012)

MPG.PuRe

216.

Zeitschriftenartikel

Dümcke, S.; Seizl, M.; Etzold, S.; Pirkl, N.; Martin, D. E.; Cramer, P.; Tresch, A.: One Hand Clapping: detection of condition-specific transcription factor interactions from genome-wide gene activity data. Nucleic Acids Research 40 (18), S. 8883 - 8892 (2012)

MPG.PuRe

ZIP

217.

Zeitschriftenartikel

Mayer, A.; Heidemann, M.; Lidschreiber, M.; Schreieck, A.; Sun, M.; Hintermair, C.; Kremmer, E.; Eick, D.; Cramer, P.: CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II. Science 336 (6089), S. 1723 - 1725 (2012)

MPG.PuRe

218.

Zeitschriftenartikel

Cheung, A. C. M.; Cramer, P.: A movie of RNA polymerase II transcription. Cell 149 (7), S. 1431 - 1437 (2012)

MPG.PuRe

219.

Zeitschriftenartikel

Niederberger, T.; Etzold, S.; Lidschreiber, M.; Maier, K. C.; Martin, D. E.; Fröhlich, H.; Cramer, P.; Tresch, A.: MC EMiNEM maps the interaction landscape of the Mediator. PLoS Computational Biology 8 (6), e1002568 (2012)

MPG.PuRe

ZIP

220.

Zeitschriftenartikel

Treutlein, B.; Muschielok, A.; Andrecka, J.; Jawhari, A.; Buchen, C.; Kostrewa, D.; Hög, F.; Cramer, P.; Michaelis, J.: Dynamic architecture of a minimal RNA polymerase II open promoter complex. Molecular Cell 46 (2), S. 136 - 146 (2012)

MPG.PuRe

221.

Zeitschriftenartikel

Walmacq, C.; Cheung, A. C. M.; Kireeva, M. L.; Lubkowska, L.; Ye, C.; Gotte, D.; Strathern, J. N.; Carell, T.; Cramer, P.; Kashlev, M.: Mechanism of translesion transcription by RNA polymerase II and its role in cellular resistance to DNA damage. Molecular Cell 46 (1), S. 18 - 29 (2012)

MPG.PuRe

222.

Zeitschriftenartikel

Sun, M.; Schwalb, B.; Schulz, D.; Pirkl, N.; Etzold, S.; Larivière, L.; Maier, K. C.; Seizl, M.; Tresch, A.; Cramer, P.: Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation. Genome Research 22 (7), S. 1350 - 1359 (2012)

MPG.PuRe

223.

Zeitschriftenartikel

Koschubs, T.; Dengl, S.; Dürr, H.; Kaluza, K.; Georges, G.; Hartl, C.; Jennewein, S.; Lanzendörfer, M.; Auer, J.; Stern, A. et al.; Huang, K.‑.; Packman, K.; Gubler, U.; Kostrewa, D.; Ries, S.; Hansen, S.; Kohnert, U.; Cramer, P.; Mundigl, O.: Allosteric antibody inhibition of human hepsin protease. Biochemical Journal 442 (3), S. 483 - 494 (2012)

MPG.PuRe

224.

Zeitschriftenartikel

Jennebach, S.; Herzog, F.; Aebersold, R.; Cramer, P.: Crosslinking-MS analysis reveals RNA polymerase I domain architecture and basis of rRNA cleavage. Nucleic Acids Research 40 (12), S. 5591 - 5601 (2012)

MPG.PuRe

225.

Zeitschriftenartikel

Wild, T.; Cramer, P.: Biogenesis of multisubunit RNA polymerases. Trends in Biochemical Sciences 37 (3), S. 99 - 105 (2012)

MPG.PuRe

226.

Zeitschriftenartikel

Vannini, A.; Cramer, P.: Conservation between the RNA polymerase I, II, and III transcription initiation machineries. Molecular Cell 45 (4), S. 439 - 446 (2012)

MPG.PuRe

227.

Zeitschriftenartikel

Larivière, L.; Seizl, M.; Cramer, P.: A structural perspective on Mediator function. Current Opinion in Cell Biology 24 (3), S. 305 - 313 (2012)

MPG.PuRe

228.

Zeitschriftenartikel

Mayer, A.; Schreieck, A.; Lidschreiber, M.; Leike, K.; Martin, D. E.; Cramer, P.: The Spt5 C-terminal region recruits yeast 3= RNA cleavage factor I. Molecular and Cellular Biology 32 (7), S. 1321 - 1331 (2012)

MPG.PuRe

229.

Zeitschriftenartikel

Schwalb, B.; Schulz, D.; Sun, M.; Zacher, B.; Dümcke, S.; Martin, D. E.; Cramer, P.; Tresch, A.: Measurement of genome-wide RNA synthesis and decay rates with Dynamic Transcriptome Analysis (DTA). Bioinformatics 28 (6), S. 884 - 885 (2012)

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230.

Zeitschriftenartikel

Cheung, A. C. M.; Sainsbury, S.; Cramer, P.: Structural basis of initial RNA polymerase II transcription. EMBO Journal 30 (23), S. 4755 - 4763 (2011)

MPG.PuRe

231.

Zeitschriftenartikel

Seizl, M.; Hartmann, H.; Hoeg, F.; Kurth, F.; Martin, D. E.; Söding, J.; Cramer, P.: A conserved GA element in TATA-less RNA polymerase II promoters. PLoS One 6 (11), e27595 (2011)

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ZIP

232.

Zeitschriftenartikel

Ringel, R.; Sologub, M.; Morozov, Y. I.; Litonin, D.; Cramer, P.; Temiakov, D.: Structure of human mitochondrial RNA polymerase. Nature 478 (7368), S. 269 - 273 (2011)

MPG.PuRe

233.

Zeitschriftenartikel

Blattner, C.; Jennebach, S.; Herzog, F.; Mayer, A.; Cheung, A. C. M.; Witte, G.; Lorenzen, K.; Hopfner, K.-P.; Heck, A. J. R.; Aebersold, R. et al.; Cramer, P.: Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth. Genes and Development 25 (19), S. 2093 - 2105 (2011)

MPG.PuRe

234.

Zeitschriftenartikel

Geiger, S. R.; Böttcher, T.; Sieber, S. A.; Cramer, P.: A conformational switch underlies ClpP protease function. Angewandte Chemie International Edition 50 (25), S. 5749 - 5752 (2011)

MPG.PuRe

235.

Zeitschriftenartikel

Czeko, E.; Seizl, M.; Augsberger, C.; Mielke, T.; Cramer, P.: Iwr1 directs RNA polymerase II nuclear import. Molecular cell 42 (2), S. 261 - 266 (2011)

MPG.PuRe

236.

Zeitschriftenartikel

Müller, M.; Heym, R. G.; Mayer, A.; Kramer, K.; Schmid, M.; Cramer, P.; Urlaub, H.; Jansen, R. P.; Niessing, D.: A cytoplasmic complex mediates specific mRNA recognition and localization in yeast. PLoS Biology 9 (4), e1000611 (2011)

MPG.PuRe

237.

Zeitschriftenartikel

Seizl, M.; Larivière, L.; Pfaffeneder, T.; Wenzeck, L.; Cramer, P.: Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization. Nucleic Acids Research 39 (14), S. 6291 - 6304 (2011)

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238.

Zeitschriftenartikel

Vojnic, E.; Mourão, A.; Seizl, M.; Simon, B.; Wenzeck, L.; Larivière, L.; Baumli, S.; Baumgart, K.; Meisterernst, M.; Sattler, M. et al.; Cramer, P.: Structure and VP16 binding of the Mediator Med25 activator interaction domain. Nature Structural and Molecular Biology 18 (4), S. 404 - 409 (2011)

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239.

Zeitschriftenartikel

Ruan, W.; Lehmann, E.; Thomm, M.; Kostrewa, D.; Cramer, P.: Evolution of two modes of intrinsic RNA polymerase transcript cleavage. Journal of Biological Chemistry 286 (21), S. 18701 - 18707 (2011)

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240.

Zeitschriftenartikel

Cheung, A. C. M.; Cramer, P.: Structural basis of RNA polymerase II backtracking, arrest and reactivation. Nature 471 (7337), S. 249 - 253 (2011)

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241.

Zeitschriftenartikel

Martinez‐Rucobo, F. W.; Sainsbury, S.; Cheung, A. C. M.; Cramer, P.: Architecture of the RNA polymerase–Spt4/5 complex and basis of universal transcription processivity. EMBO Journal 30 (7), S. 1302 - 1310 (2011)

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242.

Zeitschriftenartikel

Miller, C.; Schwalb, B.; Maier, K.; Schulz, D.; Dümcke, S.; Zacher, B.; Mayer, A.; Sydow, J.; Marcinowski, L.; Dölken, L. et al.; Martin, D. E.; Tresch, A.; Cramer, P.: Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast. Molecular Systems Biology 7, 458 (2011)

MPG.PuRe

243.

Zeitschriftenartikel

Clausing, E.; Mayer, A.; Chanarat, S.; Müller, B.; Germann, S. M.; Cramer, P.; Lisby, M.; Strässer, K.: The transcription elongation factor Bur1-Bur2 interacts with replication protein A and maintains genome stability during replication stress. Journal of Biological Chemistry 285 (53), S. 41665 - 41674 (2010)

MPG.PuRe

244.

Zeitschriftenartikel

Sun, M.; Larivière, L.; Dengl, S.; Mayer, A.; Cramer, P.: A tandem SH2 domain in transcription elongation factor Spt6 binds the phosphorylated RNA polymerase II C-terminal repeat domain (CTD). Journal of Biological Chemistry 285 (53), S. 41597 - 41603 (2010)

MPG.PuRe

245.

Zeitschriftenartikel

Beck, K.; Vannini, A.; Cramer, P.; Lipps, G.: The archaeo-eukaryotic primase of plasmid pRN1 requires a helix bundle domain for faithful primer synthesis. Nucleic Acids Research 38 (19), S. 6707 - 6718 (2010)

MPG.PuRe

246.

Zeitschriftenartikel

Vannini, A.; Ringel, R.; Kusser, A. G.; Berninghausen, O.; Kassavetis, G. A.; Cramer, P.: Molecular basis of RNA polymerase III transcription repression by Maf1. Cell 143 (1), S. 59 - 70 (2010)

MPG.PuRe

247.

Zeitschriftenartikel

Mayer, A.; Lidschreiber, M.; Siebert, M.; Leike, K.; Söding, J.; Cramer, P.: Uniform transitions of the general RNA polymerase II transcription complex. Nature Structural and Molecular Biology 17 (10), S. 1272 - 1278 (2010)

MPG.PuRe

248.

Zeitschriftenartikel

Geiger, S. R.; Lorenzen, K.; Schreieck, A.; Hanecker, P.; Kostrewa, D.; Heck, A. J. R.; Cramer, P.: RNA polymerase I contains a TFIIF-related DNA-binding subcomplex. Molecular Cell 39 (4), S. 583 - 594 (2010)

MPG.PuRe

249.

Zeitschriftenartikel

Cramer, P.: Towards molecular systems biology of gene transcription and regulation. Biological Chemistry 391 (7), S. 731 - 735 (2010)

MPG.PuRe

250.

Zeitschriftenartikel

Hirtreiter, A.; Damsma, G. E.; Cheung, A. C. M.; Klose, D.; Grohmann, D.; Vojnic, E.; Martin, A. C. R.; Cramer, P.; Werner, F.: Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif. Nucleic Acids Research 38 (12), S. 4040 - 4051 (2010)

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