Publikationen

152.

Zeitschriftenartikel

Fitz, V.; Shin, J.; Ehrlich, C.; Farnung, L.; Cramer, P.; Zaburdaev, V.; Grill, S. W.: Nucleosomal arrangement affects single-molecule transcription dynamics. Proceedings of the National Academy of Sciences of the United States of America 113 (45), S. 12733 - 12738 (2016)

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153.

Zeitschriftenartikel

Hillenbrand, P.; Maier, K. C.; Cramer, P.; Gerland, U.: Inference of gene regulation functions from dynamic transcriptome data. eLife 5, e12188 (2016)

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154.

Zeitschriftenartikel

Shao, W.; Zumer, K.; Fujinaga, K.; Peterlin, B. M.: FBXO3 protein promotes ubiquitylation and transcriptional activity of AIRE (Autoimmune Regulator). Journal of Biological Chemistry 291 (34), S. 17953 - 17963 (2016)

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155.

Zeitschriftenartikel

Cramer, P.: Structure determination of transient transcription complexes. Biochemical Society Transactions 44 (4), S. 1177 - 1182 (2016)

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156.

Zeitschriftenartikel

Engel, C.; Plitzko, J.; Cramer, P.: RNA polymerase I-Rrn3 complex at 4.8 Å resolution. Nature Communications 7, 12129 (2016)

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157.

Zeitschriftenartikel

Plaschka, C.; Nozawa, K.; Cramer, P.: Mediator architecture and RNA polymerase II interaction. Journal of Molecular Biology 428 (12), S. 2569 - 2574 (2016)

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158.

Zeitschriftenartikel

Vos, S. M.; Pöllmann, D.; Caizzi, L.; Hofmann, K. B.; Rombaut, P.; Zimniak, T.; Herzog, F.; Cramer, P.: Architecture and RNA binding of the human negative elongation factor. eLife 5, e14981 (2016)

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159.

Zeitschriftenartikel

Schwalb, B.; Michel, M.; Zacher, B.; Frühauf, K.; Demel, C.; Tresch, A.; Gagneur, J.; Cramer, P.: TT-seq maps the human transient transcriptome. Science 352 (6290), S. 1225 - 1228 (2016)

MPG.PuRe

160.

Zeitschriftenartikel

Plaschka, C.; Hantsche, M.; Dienemann, C.; Burzinski, C.; Plitzko, J.; Cramer, P.: Transcription initiation complex structures elucidate DNA opening. Nature 533 (7603), S. 353 - 358 (2016)

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161.

Zeitschriftenartikel

Lisica, A.; Engel, C.; Jahnel, M.; Roldán, É.; Galburt, E. A.; Cramer, P.; Grill, S. W.: Mechanisms of backtrack recovery by RNA polymerases I and II. Proceedings of the National Academy of Sciences of the United States of America 113 (11), S. 2946 - 2951 (2016)

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162.

Zeitschriftenartikel

Niesser, J.; Wagner, F. R.; Kostrewa, D.; Mühlbacher, W.; Cramer, P.: Structure of GPN-loop GTPase Npa3 and implications for RNA polymerase II assembly. Molecular and Cellular Biology 36 (5), S. 820 - 831 (2016)

MPG.PuRe

163.

Zeitschriftenartikel

Eser, P.; Wachutka, L.; Maier, K. C.; Demel, C.; Boroni, M.; Iyer, S.; Cramer, P.; Gagneur, J.: Determinants of RNA metabolism in the Schizosaccharomyces pombe genome. Molecular Systems Biology 12 (2), 857 (2016)

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164.

Zeitschriftenartikel

Bernecky, C.; Herzog, F.; Baumeister, W.; Plitzko, J. M.; Cramer, P.: Structure of transcribing mammalian RNA polymerase II. Nature 529 (7587), S. 551 - 554 (2016)

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165.

Zeitschriftenartikel

Schüller, R.; Forné, I.; Straub, T.; Schreieck, A.; Texier, Y.; Shah, N.; Decker, T. M.; Cramer, P.; Imhof, A.; Eick, D.: Heptad-specific phosphorylation of RNA polymerase II CTD. Molecular Cell 61 (2), S. 305 - 314 (2016)

MPG.PuRe

166.

Zeitschriftenartikel

Mühlbacher, W.; Mayer, A.; Sun, M.; Remmert, M.; Cheung, A. C. M.; Niesser, J.; Söding, J.; Cramer, P.: Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a non-canonical CTD-interacting domain fold. Proteins: Structure, Function, and Bioinformatics 83 (10), S. 1849 - 1858 (2015)

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167.

Zeitschriftenartikel

Kostrewa, D.; Kuhn, C. D.; Engel, C.; Cramer, P.: An alternative RNA polymerase I structure reveals a dimer hinge. Acta Crystallographica D 71 (9), S. 1850 - 1855 (2015)

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168.

Zeitschriftenartikel

Martinez-Rucobo, F. W.; Kohler, R.; Waterbeemd, M. v. d.; Heck, A. J.; Hemann, M.; Herzog, F.; Stark, H.; Cramer, P.: Molecular basis of transcription-coupled pre-mRNA capping. Molecular Cell 58 (6), S. 1079 - 1089 (2015)

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169.

Zeitschriftenartikel

Morozov, Y. I.; Parshin, A. V.; Agaronyan, K.; Cheung, A. C.; Anikin, M.; Cramer, P.; Temiakov, D.: A model for transcription initiation in human mitochondria. Nucleic Acids Research 43 (7), S. 3726 - 3735 (2015)

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170.

Zeitschriftenartikel

Sainsbury, S.; Bernecky, C.; Cramer, P.: Structural basis of transcription initiation by RNA polymerase II. Nature Reviews Molecular Cell Biology 16 (3), S. 129 - 143 (2015)

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171.

Zeitschriftenartikel

Plaschka, C.; Larivière, L.; Wenzeck, L.; Seizl, M.; Hemann, M.; Tegunov, D.; Petrotchenko, E. V.; Borchers, C. H.; Baumeister, W.; Herzog, F. et al.; Villa, E.; Cramer, P.: Architecture of the RNA polymerase II–Mediator core initiation complex. Nature 518 (7539), S. 376 - 380 (2015)

MPG.PuRe

172.

Zeitschriftenartikel

Borck, G.; Hög, F.; Dentici, M. L.; Tan, P. L.; Sowada, N.; Medeira, A.; Gueneau, L.; Thiele, H.; Kousi, M.; Lepri, F. et al.; Wenzeck, L.; Blumenthal, I.; Radicioni, A.; Schwarzenberg, T. L.; Mandriani, B.; Fischetto, R.; Morris-Rosendahl, D. J.; Altmüller, J.; Reymond, A.; Nürnberg, P.; Merla, G.; Dallapiccola, B.; Katsanis, N.; Cramer, P.; Kubisch, C.: BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies. Genome Research 25 (2), S. 155 - 166 (2015)

MPG.PuRe

173.

Zeitschriftenartikel

Zacher, B.; Lidschreiber, M.; Cramer, P.; Gagneur, J.; Tresch, A.: Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle. Molecular Systems Biology 10 (12), 768 (2014)

MPG.PuRe

ZIP

174.

Zeitschriftenartikel

Cramer, P.: A tale of chromatin and transcription in 100 structures. Cell 159 (5), S. 985 - 994 (2014)

MPG.PuRe

175.

Zeitschriftenartikel

Bäjen, C.; Torkler, P.; Gressel, S.; Essig, K.; Söding, J.; Cramer, P.: Transcriptome maps of mRNP biogenesis factors define pre-mRNA recognition. Molecular Cell 55 (5), S. 745 - 757 (2014)

MPG.PuRe

176.

Zeitschriftenartikel

Tudek, A.; Porrua, O.; Kabzinski, T.; Lidschreiber, M.; Kubicek, K.; Fortova, A.; Lacroute, F.; Vanakova, S.; Cramer, P.; Stefl, R. et al.; Libri, D.: Molecular basis for coordinating transcription termination with noncoding RNA degradation. Molecular Cell 55 (3), S. 467 - 481 (2014)

MPG.PuRe

177.

Zeitschriftenartikel

Mühlbacher, W.; Sainsbury, S.; Hemann, M.; Hantsche, M.; Neyer, S.; Herzog, F.; Cramer, P.: Conserved architecture of the core RNA polymerase II initiation complex. Nature Communications 5, 4310 (2014)

MPG.PuRe

178.

Zeitschriftenartikel

Sydow, J. F.; Lipsmeier, F.; Larraillet, V.; Hilger, M.; Mautz, B.; Mølhøj, M.; Kuentzer, J.; Klostermann, S.; Schoch, J.; Voelger, H. R. et al.; Regula, J. T.; Cramer, P.; Papadimitriou, A.; Kettenberger, H.: Structure-based prediction of asparagine and aspartate degradation sites in antibody variable regions. PLoS One 9 (6), e100736 (2014)

MPG.PuRe

179.

Zeitschriftenartikel

Schulz, D.; Pirkl, N.; Lehmann, E.; Cramer, P.: Rpb4 functions mainly in mRNA synthesis by RNA polymerase II. Journal of Biological Chemistry 289 (25), S. 17446 - 17452 (2014)

MPG.PuRe

180.

Zeitschriftenartikel

Hirschmann, W. D.; Westendorf, H.; Mayer, A.; Cannarozzi, G.; Cramer, P.; Jansen, R. P.: Scp160p is required for translational efficiency of codon-optimized mRNAs in yeast. Nucleic Acids Research 42 (6), S. 4043 - 4055 (2014)

MPG.PuRe

181.

Zeitschriftenartikel

Morozov, Y. I.; Agaronyan, K.; Cheung, A. C. M.; Anikin, M.; Cramer, P.; Temiakov, D.: A novel intermediate in transcription initiation by human mitochondrial RNA polymerase. Nucleic Acids Research 42 (6), S. 3884 - 3893 (2014)

MPG.PuRe

182.

Zeitschriftenartikel

Schreieck, A.; Easter, A. D.; Etzold, S.; Wiederhold, K.; Lidschreiber, M.; Cramer, P.; Passmore, L. A.: RNA polymerase II termination involves C-terminal-domain tyrosine dephosphorylation by CPF subunit Glc7. Nature Structural and Molecular Biology 21 (2), S. 175 - 179 (2014)

MPG.PuRe

183.

Zeitschriftenartikel

Eser, P.; Demel, C.; Maier, K. C.; Schwalb, B.; Pirkl, N.; Martin, D. E.; Cramer, P.; Tresch, A.: Periodic mRNA synthesis and degradation co-operate during cell cycle gene expression. Molecular Systems Biology 10 (1), 717 (2014)

MPG.PuRe

184.

Zeitschriftenartikel

Meinel, D. M.; Burkert-Kautzsch, C.; Kieser, A.; O'Duibhir, E.; Siebert, M.; Mayer, A.; Cramer, P.; Söding, J.; Holstege, F. C.; Sträßer, K.: Recruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II. PLoS Genetics 9 (11), e1003914 (2013)

MPG.PuRe

185.

Zeitschriftenartikel

Schulz, D.; Schwalb, B.; Kiesel, A.; Baejen, C.; Torkler, P.; Gagneur, J.; Söding, J.; Cramer, P.: Transcriptome surveillance by selective termination of noncoding RNA synthesis. Cell 155 (5), S. 1075 - 1087 (2013)

MPG.PuRe

186.

Zeitschriftenartikel

Heo, D.-h.; Yoo, I.; Kong, J.; Lidschreiber, M.; Mayer, A.; Choi, B.-Y.; Hahn, Y.; Cramer, P.; Buratowski, S.; Kim, M.: The RNA polymerase II C-terminal domain-interacting domain of yeast Nrd1 contributes to the choice of termination pathway and couples to RNA processing by the nuclear exosome. Journal of Biological Chemistry 288 (51), S. 36676 - 36690 (2013)

MPG.PuRe

187.

Zeitschriftenartikel

Engel, C.; Sainsbury, S.; Cheung, A. C.; Kostrewa, D.; Cramer, P.: RNA polymerase I structure and transcription regulation. Nature 502 (7473), S. 650 - 655 (2013)

MPG.PuRe

188.

Zeitschriftenartikel

Sun, M.; Schwalb, B.; Pirkl, N.; Maier, K. C.; Schenk, A.; Failmezger, H.; Tresch, A.; Cramer, P.: Global analysis of eukaryotic mRNA degradation reveals Xrn1-dependent buffering of transcript levels. Molecular cell 52 (1), S. 52 - 62 (2013)

MPG.PuRe

189.

Zeitschriftenartikel

Schwinghammer, K.; Cheung, A. C. M.; Morozov, Y. I.; Agaronyan, K.; Temiakov, D.; Cramer, P.: Structure of human mitochondrial RNA polymerase elongation complex. Nature Structural and Molecular Biology 20 (11), S. 1298 - 1303 (2013)

MPG.PuRe

190.

Zeitschriftenartikel

Kinkelin, K.; Wozniak, G. G.; Rothbart, S. B.; Lidschreiber, M.; Strahl, B. D.; Cramer, P.: Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue. Proceedings of the National Academy of Sciences of the USA 110 (38), S. 15277 - 15282 (2013)

MPG.PuRe

191.

Zeitschriftenartikel

Larivière, L.; Plaschka, C.; Seizl, M.; Petrotchenko, E. V.; Wenzeck, L.; Borchers, C. H.; Cramer, P.: Model of the Mediator middle module based on protein cross-linking. Nucleic Acids Research 41 (20), S. 9266 - 9273 (2013)

MPG.PuRe

192.

Zeitschriftenartikel

Lidschreiber, M.; Leike, K.; Cramer, P.: Cap completion and C-terminal repeat domain kinase recruitment underlie the initiation-elongation transition of RNA polymerase II. Molecular and cellular biology 33 (19), S. 3805 - 3816 (2013)

MPG.PuRe

193.

Zeitschriftenartikel

Fouqueau, T.; Zeller, M. E.; Cheung, A. C.; Cramer, P.; Thomm, M.: The RNA polymerase trigger loop functions in all three phases of the transcription cycle. Nucleic acids research 41 (14), S. 7048 - 7059 (2013)

MPG.PuRe

194.

Zeitschriftenartikel

Michel, M.; Cramer, P.: Transitions for regulating early transcription. Cell 153 (5), S. 943 - 944 (2013)

MPG.PuRe

195.

Zeitschriftenartikel

Esslinger, S. M.; Schwalb, B.; Helfer, S.; Michalik, K. M.; Witte, H.; Maier, K. C.; Martin, D.; Michalke, B.; Tresch, A.; Cramer, P. et al.; Förstemann, K.: Drosophila miR-277 controls branched-chain amino acid catabolism and affects lifespan. RNA Biology 10 (6), S. 1042 - 1056 (2013)

MPG.PuRe

196.

Zeitschriftenartikel

Bernecky, C.; Cramer, P.: Struggling to let go: A non‐coding RNA directs its own extension and destruction. EMBO Journal 32 (6), S. 771 - 772 (2013)

MPG.PuRe

197.

Zeitschriftenartikel

Sainsbury, S.; Niesser, J.; Cramer, P.: Structure and function of the initially transcribing RNA polymerase II–TFIIB complex. Nature 493 (7432), S. 437 - 440 (2013)

MPG.PuRe

198.

Zeitschriftenartikel

Martinez-Rucobo, F. W.; Cramer, P.: Structural basis of transcription elongation. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1829 (1), S. 9 - 19 (2013)

MPG.PuRe

199.

Zeitschriftenartikel

Larivière, L.; Plaschka, C.; Seizl, M.; Wenzeck, L.; Kurth, F.; Cramer, P.: Structure of the Mediator head module. Nature 492 (7429), S. 448 - 451 (2012)

MPG.PuRe

200.

Zeitschriftenartikel

Miller, C.; Matic, I.; Maier, K. C.; Schwalb, B.; Roether, S.; Strässer, K.; Tresch, A.; Mann, M.; Cramer, P.: Mediator phosphorylation prevents stress response transcription during non-stress conditions. Journal of Biological Chemistry 287 (53), S. 44017 - 44026 (2012)

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