Publikationen
Zeitschriftenartikel (44)
1.
Zeitschriftenartikel
15 (1), 1147 (2024)
Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing. Nature Communications 2.
Zeitschriftenartikel
186 (24), S. 5308 - 5327.e25 (2023)
Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices. Cell 3.
Zeitschriftenartikel
10, 18 (2023)
InvitroSPI and a large database of proteasome-generated spliced and non-spliced peptides. Scientific Data 4.
Zeitschriftenartikel
23 (2), 2200271 (2023)
iBench: A ground truth approach for advanced validation of mass spectrometry identification method. Proteomics 5.
Zeitschriftenartikel
21 (12), 100432 (2022)
inSPIRE: An open-source tool for increased mass spectrometry identification rates using Prosit spectral prediction. Molecular and Cellular Proteomics 6.
Zeitschriftenartikel
7, S. 23771 - 23781 (2022)
Predicting the Success of Fmoc-Based Peptide Synthesis. ACS Omega 7.
Zeitschriftenartikel
22 (10), e2100226 (2022)
Database search engines and target database features impinge upon the identification of post‐translationally cis‐spliced peptides in HLA class I immunopeptidomes. Proteomics 8.
Zeitschriftenartikel
12 (2), 166 (2022)
Computational Models for Clinical Applications in Personalized Medicine—Guidelines and Recommendations for Data Integration and Model Validation. Journal of Personalized Medicine 9.
Zeitschriftenartikel
12, 679836 (2021)
Response: Commentary: An In Silico–In Vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients. Frontiers in immunology 10.
Zeitschriftenartikel
36 (1), 109312 (2021)
Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides. Cell Reports 11.
Zeitschriftenartikel
12, 656451 (2021)
Potential mimicry of viral and pancreatic β cell antigens through non-spliced and cis-spliced zwitter epitope candidates in Type 1 Diabetes. Frontiers in Immunology 12.
Zeitschriftenartikel
12, 614276 (2021)
Proteasome-generated cis-spliced peptides and their potential role in CD8+ T cell tolerance. Frontiers in Immunology 13.
Zeitschriftenartikel
7, 146 (2020)
Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes. Scientific Data 14.
Zeitschriftenartikel
50 (2), S. 270 - 283 (2020)
ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope. European Journal of Immunology 15.
Zeitschriftenartikel
269, S. 146 - 158 (2019)
Eigenvector-based identification of bipartite subgraphs. Discrete Applied Mathematics 16.
Zeitschriftenartikel
294, S. 7740 - 7754 (2019)
Proteolytic dynamics of human 20S thymoproteasome. Journal of Biological Chemistry 17.
Zeitschriftenartikel
8 (3), 262 (2019)
Untangling extracellular proteasome-osteopontin circuit dynamics in multiple sclerosis. Cells 18.
Zeitschriftenartikel
7 (1), S. 62 - 76 (2019)
Mapping the MHC class I spliced immunopeptidome of cancer cells. Cancer Immunology Research 19.
Zeitschriftenartikel
10, 2572 (2019)
An in silico-in vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients. Frontiers in Immunology 20.
Zeitschriftenartikel
52, S. 81 - 86 (2018)
Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? Current Opinion in Immunology 21.
Zeitschriftenartikel
34 (7), S. 1249 - 1250 (2018)
PEITH(Θ) - perfecting experiments with information theory in python with GPU support. Bioinformatics 22.
Zeitschriftenartikel
38 (12), S. 904 - 915 (2017)
Post-translational peptide splicing and T cell responses. Trends in Immunology 23.
Zeitschriftenartikel
8, 1441 (2017)
An unexpected major role for proteasome-catalyzed peptide splicing in generation of T cell epitopes: Is there relevance for vaccine development? Frontiers in Immunology 24.
Zeitschriftenartikel
35 (11), S. 2292 - 2304 (2017)
Single cell phenotyping reveals heterogeneity among haematopoietic stem cells following infection. Stem Cells 25.
Zeitschriftenartikel
20 (5), S. 1242 - 1253 (2017)
Multi-level strategy for identifying proteasome-catalyzed spliced epitopes targeted by CD8+ T cells during bacterial infection. Cell Reports 26.
Zeitschriftenartikel
7, 43718 (2017)
Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis. Scientific Reports 27.
Zeitschriftenartikel
354 (6310), S. 354 - 358 (2016)
A large fraction of HLA class I ligands are proteasome-generated spliced peptides. Science 28.
Zeitschriftenartikel
26 (15), S. 1975 - 1989 (2016)
Systems analysis of the dynamic inflammatory response to tissue damage reveals spatiotemporal properties of the wound attractant gradient. Current Biology 29.
Zeitschriftenartikel
3 (1), S. 102 - 107 (2016)
Accurate reconstruction of cell and particle tracks from 3D live imaging data. Cell Systems 30.
Zeitschriftenartikel
46 (5), S. 1109 - 1118 (2016)
CD8(+) T cells of Listeria monocytogenes-infected mice recognize both linear and spliced proteasome products. European Journal of Immunology 31.
Zeitschriftenartikel
290 (51), S. 30417 - 30428 (2015)
The T210M substitution in the HLA-a*02:01 gp100 epitope strongly affects overall proteasomal cleavage site usage and antigen processing. Journal of Biological Chemistry 32.
Zeitschriftenartikel
12 (6), 066001 (2015)
Inference of random walk models to describe leukocyte migration. Physical Biology 33.
Zeitschriftenartikel
4, e07545 (2015)
Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes. eLife 34.
Zeitschriftenartikel
91 (4), 042115 (2015)
Goldstein-Kac telegraph processes with random speeds: Path probabilities, likelihoods, and reported Lévy flights. Physical Review E 35.
Zeitschriftenartikel
44 (12), S. 3508 - 3521 (2014)
Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation. European Journal of Immunology 36.
Zeitschriftenartikel
35, S. 98 - 108 (2014)
Information theory and signal transduction systems: From molecular information processing to network inference. Seminars in Cell and Developmental Biology 37.
Zeitschriftenartikel
4 (2), S. 585 - 599 (2014)
Modelling proteasome and proteasome regulator activities. Biomolecules 38.
Zeitschriftenartikel
9, S. 439 - 456 (2014)
A framework for parameter estimation and model selection from experimental data in systems biology using approximate Bayesian computation. Nature Protocols 39.
Zeitschriftenartikel
9 (1), e1002888 (2013)
Maximizing the information content of experiments in systems biology. PLoS Computational Biology 40.
Zeitschriftenartikel
91 (1), S. 60 - 69 (2013)
P38 and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish. Immunology and Cell Biology 41.
Zeitschriftenartikel
4 (3), S. 335 - 345 (2012)
Calibrating spatio-temporal models of leukocyte dynamics against in vivo live-imaging data using approximate Bayesian computation. Integrative Biology 42.
Zeitschriftenartikel
27 (6), S. 874 - 876 (2011)
GPU accelerated biochemical network simulation. Bioinformatics 43.
Zeitschriftenartikel
26 (14), S. 1797 - 1799 (2010)
ABC-SysBio-approximate Bayesian computation in Python with GPU support. Bioinformatics 44.
Zeitschriftenartikel
6 (6), e1000830 (2010)
The 20S proteasome splicing activity discovered by SpliceMet. PLoS Computational Biology Buchkapitel (1)
45.
Buchkapitel
ABC in systems biology. In: Handbook of approximate bayesian computation (Hg. Sisson, S. A.; Fan, Y.; Beaumont, M. A.) (2019)