Publikationen
Zeitschriftenartikel (49)
1.
Zeitschriftenartikel
269, 106899 (2024)
Proteasome isoforms in human thymi and mouse models. Immunology Letters 2.
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A roadmap for ribosome assembly in human mitochondria. Nature Structural & Molecular Biology (2024)
3.
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5, 1426816 (2024)
Spatiotemporal proteolytic susceptibility of allergens: positive or negative effects on the allergic sensitization? Frontiers in Allergy 4.
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26, S. 1124 - 1138 (2024)
The maintenance of oocytes in the mammalian ovary involves extreme protein longevity. Nature Cell Biology 5.
Zeitschriftenartikel
15 (1), 1147 (2024)
Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing. Nature Communications 6.
Zeitschriftenartikel
56, 8 (2024)
Merging of Neural Networks. Neural Processing Letters 7.
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186 (24), S. 5308 - 5327.e25 (2023)
Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices. Cell 8.
Zeitschriftenartikel
10, 18 (2023)
InvitroSPI and a large database of proteasome-generated spliced and non-spliced peptides. Scientific Data 9.
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23 (2), 2200271 (2023)
iBench: A ground truth approach for advanced validation of mass spectrometry identification method. Proteomics 10.
Zeitschriftenartikel
21 (12), 100432 (2022)
inSPIRE: An open-source tool for increased mass spectrometry identification rates using Prosit spectral prediction. Molecular and Cellular Proteomics 11.
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7, S. 23771 - 23781 (2022)
Predicting the Success of Fmoc-Based Peptide Synthesis. ACS Omega 12.
Zeitschriftenartikel
22 (10), e2100226 (2022)
Database search engines and target database features impinge upon the identification of post‐translationally cis‐spliced peptides in HLA class I immunopeptidomes. Proteomics 13.
Zeitschriftenartikel
12 (2), 166 (2022)
Computational Models for Clinical Applications in Personalized Medicine—Guidelines and Recommendations for Data Integration and Model Validation. Journal of Personalized Medicine 14.
Zeitschriftenartikel
12, 679836 (2021)
Response: Commentary: An In Silico–In Vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients. Frontiers in immunology 15.
Zeitschriftenartikel
36 (1), 109312 (2021)
Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides. Cell Reports 16.
Zeitschriftenartikel
12, 656451 (2021)
Potential mimicry of viral and pancreatic β cell antigens through non-spliced and cis-spliced zwitter epitope candidates in Type 1 Diabetes. Frontiers in Immunology 17.
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12, 614276 (2021)
Proteasome-generated cis-spliced peptides and their potential role in CD8+ T cell tolerance. Frontiers in Immunology 18.
Zeitschriftenartikel
7, 146 (2020)
Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes. Scientific Data 19.
Zeitschriftenartikel
50 (2), S. 270 - 283 (2020)
ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope. European Journal of Immunology 20.
Zeitschriftenartikel
269, S. 146 - 158 (2019)
Eigenvector-based identification of bipartite subgraphs. Discrete Applied Mathematics 21.
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294, S. 7740 - 7754 (2019)
Proteolytic dynamics of human 20S thymoproteasome. Journal of Biological Chemistry 22.
Zeitschriftenartikel
8 (3), 262 (2019)
Untangling extracellular proteasome-osteopontin circuit dynamics in multiple sclerosis. Cells 23.
Zeitschriftenartikel
7 (1), S. 62 - 76 (2019)
Mapping the MHC class I spliced immunopeptidome of cancer cells. Cancer Immunology Research 24.
Zeitschriftenartikel
10, 2572 (2019)
An in silico-in vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients. Frontiers in Immunology 25.
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52, S. 81 - 86 (2018)
Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? Current Opinion in Immunology 26.
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34 (7), S. 1249 - 1250 (2018)
PEITH(Θ) - perfecting experiments with information theory in python with GPU support. Bioinformatics 27.
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38 (12), S. 904 - 915 (2017)
Post-translational peptide splicing and T cell responses. Trends in Immunology 28.
Zeitschriftenartikel
8, 1441 (2017)
An unexpected major role for proteasome-catalyzed peptide splicing in generation of T cell epitopes: Is there relevance for vaccine development? Frontiers in Immunology 29.
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35 (11), S. 2292 - 2304 (2017)
Single cell phenotyping reveals heterogeneity among haematopoietic stem cells following infection. Stem Cells 30.
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20 (5), S. 1242 - 1253 (2017)
Multi-level strategy for identifying proteasome-catalyzed spliced epitopes targeted by CD8+ T cells during bacterial infection. Cell Reports 31.
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7, 43718 (2017)
Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis. Scientific Reports 32.
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354 (6310), S. 354 - 358 (2016)
A large fraction of HLA class I ligands are proteasome-generated spliced peptides. Science 33.
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26 (15), S. 1975 - 1989 (2016)
Systems analysis of the dynamic inflammatory response to tissue damage reveals spatiotemporal properties of the wound attractant gradient. Current Biology 34.
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3 (1), S. 102 - 107 (2016)
Accurate reconstruction of cell and particle tracks from 3D live imaging data. Cell Systems 35.
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46 (5), S. 1109 - 1118 (2016)
CD8(+) T cells of Listeria monocytogenes-infected mice recognize both linear and spliced proteasome products. European Journal of Immunology 36.
Zeitschriftenartikel
290 (51), S. 30417 - 30428 (2015)
The T210M substitution in the HLA-a*02:01 gp100 epitope strongly affects overall proteasomal cleavage site usage and antigen processing. Journal of Biological Chemistry 37.
Zeitschriftenartikel
12 (6), 066001 (2015)
Inference of random walk models to describe leukocyte migration. Physical Biology 38.
Zeitschriftenartikel
4, e07545 (2015)
Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes. eLife 39.
Zeitschriftenartikel
91 (4), 042115 (2015)
Goldstein-Kac telegraph processes with random speeds: Path probabilities, likelihoods, and reported Lévy flights. Physical Review E 40.
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44 (12), S. 3508 - 3521 (2014)
Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation. European Journal of Immunology 41.
Zeitschriftenartikel
35, S. 98 - 108 (2014)
Information theory and signal transduction systems: From molecular information processing to network inference. Seminars in Cell and Developmental Biology 42.
Zeitschriftenartikel
4 (2), S. 585 - 599 (2014)
Modelling proteasome and proteasome regulator activities. Biomolecules 43.
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9, S. 439 - 456 (2014)
A framework for parameter estimation and model selection from experimental data in systems biology using approximate Bayesian computation. Nature Protocols 44.
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9 (1), e1002888 (2013)
Maximizing the information content of experiments in systems biology. PLoS Computational Biology 45.
Zeitschriftenartikel
91 (1), S. 60 - 69 (2013)
P38 and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish. Immunology and Cell Biology 46.
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4 (3), S. 335 - 345 (2012)
Calibrating spatio-temporal models of leukocyte dynamics against in vivo live-imaging data using approximate Bayesian computation. Integrative Biology 47.
Zeitschriftenartikel
27 (6), S. 874 - 876 (2011)
GPU accelerated biochemical network simulation. Bioinformatics 48.
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26 (14), S. 1797 - 1799 (2010)
ABC-SysBio-approximate Bayesian computation in Python with GPU support. Bioinformatics 49.
Zeitschriftenartikel
6 (6), e1000830 (2010)
The 20S proteasome splicing activity discovered by SpliceMet. PLoS Computational Biology Buchkapitel (1)
50.
Buchkapitel
ABC in systems biology. In: Handbook of approximate bayesian computation (Hg. Sisson, S. A.; Fan, Y.; Beaumont, M. A.) (2019)