Publications

Lissek, T.; Adams, M.; Adelman, J.; Ahissar, E.; Akaaboune, M.; Akil, H.; al'Absi, M.; Arain, F.; Arango-Lasprilla, J. C.; Atasoy, D. et al.; Avila, J.; Badawi, A.; Bading, H.; Baig, A. M.; Baleriola, J.; Belmonte, C.; Bertocchi, I.; Betz, H.; Blakemore, C.; Blanke, O.; Boehm-Sturm, P.; Bonhoeffer, T.; Bonifazi, P.; Brose, N.; Campolongo, P.; Celikel, T.; Chang, C. C.; Chang, T.-Y.; Citri, A.; Cline, H. T.; Cortes, J. M.; Cullen, K.; Dean, K.; Delgado-Garcia, J. M.; Desroches, M.; Disterhoft, J. F.; Dowling, J. E.; Draguhn, A.; El-Khamisy, S. F.; El Manira, A.; Enam, S. A.; Encinas, J. M.; Erramuzpe, A.; Esteban, J. A.; Fariñas, I.; Fischer, E.; Fukunaga, I.; Gabilondo, I.; Ganten, D.; Gidon, A.; Gomez-Esteban, J. C.; Greengard, P.; Grinevich, V.; Gruart, A.; Guillemin, R.; Hariri, A. R.; Hassan, B.; Häusser, M.; Hayashi, H.; Hussain, N. K.; Jabbar, A. A.; Jaber, M.; Jahn, R.; Janahi, E. M.; Kabbaj, M.; Kettenmann, H.; Kindt, M.; Knafo, S.; Köhr, G.; Komai, S.; Krugers, H.; Kuhn, B.; Lakhdar Ghazal, N.; Larkum, M. E.; London, M.; Lutz, B.; Matute, C.; Martinez-Millan, L.; Maroun, M.; McGaugh, J.; Moustafa, A. A.; Nasim, A.; Nave, K.-A.; Neher, E.; Nikolich, K.; Outeiro, T.; Palmer, L. M.; Penagarikano, O.; Perez-Otano, I.; Pfaff, D. W.; Poucet, B.; Rahman, A.-u.; Ramos-Cabrer, P.; Rashidy-Pour, A.; Roberts, R. J.; Rodrigues, S.; Sanes, J. R.; Schaefer, A. T.; Segal, M.; Segev, I.; Shafqat, S.; Siddiqui, N. A.; Soreq, H.; Soriano-García, E.; Spanagel, R.; Sprengel, R.; Stuart, G.; Südhof, T. C.; Tønnesen, J.; Treviño, M.; Uthman, B. M.; Venter, J. C.; Verkhratsky, A.; Weiss, C.; Wiesel, T. N.; Yaksi, E.; Yizhar, O.; Young, L. J.; Young, P.; Zawia, N. H.; Zugaza, J. L.; Hasan, M. T.: Building Bridges through Science. Neuron 96 (4), pp. 730 - 735 (2017)

Crosby, J. R.; Zhao, C.; Jiang, C.; Bai, D.; Katz, M.; Greenlee, S.; Kawabe, H.; McCaleb, M.; Rotin, D.; Guo, S. et al.; Monia, B. P.: Inhaled ENaC antisense oligonucleotide ameliorates cystic fibrosis-like lung disease in mice. Journal of cystic fibrosis 16 (6), pp. 671 - 680 (2017)

Ferreira, D. G.; Temido-Ferreira, M.; Miranda, H. V.; Batalha, V. L.; Coelho, J. E.; Szegö, É. M.; Marques-Morgado, I.; Vaz, S. H.; Rhee, J. S.; Schmitz, M. et al.; Zerr, I.; Lopes, L. V.; Outeiro, T. F.: Alpha-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B. Nature Neuroscience 20 (11), pp. 1569 - 1579 (2017)

Gámez-Díaz, L.; Neumann, J.; Jäger, F.; Proietti, M.; Felber, F.; Soulas-Sprauel, P.; Perruzza, L.; Grassi, F.; Kögl, T.; Aichele, P. et al.; Kilimann, M. W.; Grimbacher, B.; Jung, S.: Immunological phenotype of the murine Lrba knockout. Immunology and Cell Biology 95 (9), pp. 789 - 802 (2017)

Vogl, C.; Butola, T.; Haag, N.; Hausrat, T. J.; Leitner, M. G.; Moutschen, M.; Lefèbre, P. P.; Speckmann, C.; Garrett, L.; Becker, L. et al.; Fuchs , H.; Hrabe de Angelis, M.; Nietzsche, S.; Kessels, M. M.; Oliver, D.; Kneussel, M.; Kilimann, M. W.; Strenzke, N.: The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing. EMBO Reports 18 (11), pp. 2015 - 2029 (2017)

Henshall, T. L.; Manning, J. A.; Alfassy, O. S.; Goel, P.; Boase, N. A.; Kawabe, H.; Kumar, S.: Deletion of Nedd4-2 results in progressive kidney disease in mice. Cell Death and Differentiation 24, pp. 2150 - 2160 (2017)

Kurtenbach, S.; Gießl, A.; Strömberg, S.; Kremers, J.; Atori, J.; Rasche, S.; Neuhaus, E. M.; Hervé, D.; Brandstätter, J. H.; Asan, E. et al.; Hatt, H.; Kilimann, M. W.: The BEACH protein LRBA promotes the localization of the heterotrimeric G-protein G(olf) to olfactory cilia. Scientific Reports 7, 8409 (2017)

Lai, Y.; Choi, U. B.; Leitz, J.; Rhee, H. J.; Lee, C.; Altas, B.; Zhao, M.; Pfuetzner, R. A.; Wang, A. L.; Brose, N. et al.; Rhee, J.; Brunger, A. T.: Molecular mechanisms of synaptic vesicle priming by Munc13 and Munc18. Neuron 95 (3), pp. 591 - 607.e10 (2017)

Hoon, M.; Krishnamoorthy, V.; Gollisch, T.; Falkenburger, B.; Varoqueaux, F.: Loss of Neuroligin3 specifically downregulates retinal GABA(Aα)2 receptors without abolishing direction selectivity. PLoS One 12 (7), e0181011 (2017)

Daniel, J. A.; Cooper, B. H.; Palvimo, J. J.; Zhang, F.-P.; Brose, N.; Tirard, M.: Analysis of SUMO1-conjugation at synapses. eLife 6, e26338 (2017)

Zhou, Z.; Kawabe, H.; Suzuki, A.; Shinmyozu, K.; Saga, Y.: NEDD4 controls spermatogonial stem cell homeostasis and stress response by regulating messenger ribonucleoprotein complexes. Nature Communications 8, 15662 (2017)

Lahut, S.; Gispert, S.; Ömür, Ö.; Depboylu, C.; Seidel, K.; Domínguez-Bautista, J. A.; Brehm, N.; Tireli, H.; Hackmann, K.; Pirkevi, C. et al.; Leube, B.; Ries, V.; Reim, K.; Brose, N.; den Dunnen, W. F.; Johnson, M.; Wolf, Z.; Schindewolf, M.; Schrempf, W.; Reetz, K.; Young, P.; Vadasz, D.; Frangakis, A. S.; Schröck, E.; Steinmetz, H.; Jendrach, M.; Rüb, U.; Basak, A. N.; Oertel, W.; Auburger, G.: Blood RNA biomarkers in prodromal PARK4 and REM sleep behavior disorder show role of complexin-1 lass for risk of Parkinson's diseaseA. Disease models and mechanisms 10 (5), pp. 619 - 631 (2017)

Krueger-Burg, D.; Papadopoulos, T.; Brose, N.: Organizers of inhibitory synapses come of age. Current Opinion in Neurobiology 45, pp. 66 - 77 (2017)

Sigler, A.; Oh, W. C.; Imig, C.; Altas, B.; Kawabe, H.; Cooper, B. H.; Kwon, H.-B.; Rhee, J.-S.; Brose, N.: Formation and maintenance of functional spines in the absence of presynaptic glutamate release. Neuron 94, pp. 304 - 311 (2017)

Kawabe, H.; Mitkovski, M.; Kaeser, P. S.; Hirrlinger, J.; Opazo, F.; Nestvogel, D.; Kalla, S.; Fejtova, A.; Verrier, S. E.; Bungers, S. R. et al.; Cooper, B. H.; Varoqueaux, F.; Wang, Y.; Nehring, R. B.; Gundelfinger, E. D.; Rosenmund, C.; Rizzoli, S. O.; Südhof, T. C.; Rhee, J.-S.; Brose, N.: ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones. The Journal of Cell Biology 216 (4), pp. 1143 - 1161 (2017)

Roh, J. D.; Choi, S.-Y.; Cho, Y. S.; Choi, T.-Y.; Park, J.-S.; Cutforth, T.; Chung, W.; Park, H.; Lee, D.; Kim, M.-H. et al.; Lee, Y.; Mo, S.; Rhee, J.-S.; Kim, H.; Ko, J.; Choi, S.-Y.; Bae, Y. C.; Shen, K.; Kim, E.; Han, K.: Increased excitatory synaptic transmission of dentate granule neurons in mice lacking PSD-95-interacting adhesion molecule Neph2/Kirrel3 during the early postnatal period. Frontiers in Molecular Neuroscience 10, 81 (2017)

Lipstein, N.; Götz, M.; Piotrowski, C.; Pagel, K.; Sinz, A.; Jahn, O.: Presynaptic calmodulin targets: lessons from structural proteomics. Expert Review of Proteomics 14 (3), pp. 223 - 242 (2017)

Lipstein, N.; Verhoeven-Duif, N. M.; Michelassi, F. E.; Calloway, N.; van Hasselt, P. M.; Pienkowska, K.; van Haaften, G.; van Haelst, M. M.; van Empelen, R.; Cuppen, I. et al.; van Teeseling, H. C.; Evelein, A. M. V.; Vorstman, J. A.; Thoms, S.; Jahn, O.; Duran, K. J.; Monroe, G. R.; Ryan, T. A.; Taschenberger, H.; Dittman, J. S.; Rhee, J.; Visser, G.; Jans, J. J.; Brose, N.: Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder. The Journal of Clinical Investigation 127 (3), pp. 1005 - 1018 (2017)

Picher, M. M.; Gehrt, A.; Meese, S.; Ivanovic, A.; Predoehl, F.; Jung, S. Y.; Schrauwen, I.; Dragonetti, A. G.; Colombo, R.; Van Camp, G. et al.; Strenzke, N.; Moser, T.: Ca2+-binding protein 2 inhibits Ca2+-channel inactivation in mouse inner hair cells. Proceedings of the National Academy of Sciences of the United States of America 114 (9), pp. E1717 - E1726 (2017)

Ripamonti, S.; Ambrozkiewicz, M.; Guzzi, F.; Gravati, M.; Biella, G.; Bormuth, I.; Hammer, M.; Tuffy, L.; Sigler, A.; Kawabe, H. et al.; Nishimori, K.; Toselli, M.; Brose, N.; Parenti, M.; Rhee, J.: Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. eLife 6, e22466 (2017)

Papadopoulos, T.; Rhee, H. J.; Subramanian, D.; Paraskevopoulou, F.; Mueller, R.; Schultz, C.; Brose, N.; Rhee, J.-S.; Betz, H.: Endosomal phosphatidylinositol 3-phosphate promotes gephyrin clustering and GABAergic neurotransmission at inhibitory postsynapses. The Journal of Biological Chemistry 292 (4), pp. 1160 - 1177 (2017)

Altas, B.; Jahn, O.; Kawabe, H.: Biochemical purification of binding partners of synaptic scaffold proteins. Methods in molecular biology 1538, pp. 69 - 82 (2017)

Chehab, T.; Criado Santos, N.; Holthenrich, A.; Koerdt, S. N.; Disse, J.; Schuberth, C.; Nazmi, A. R.; Neeft, M.; Koch, H.; Man, K.-n. M. et al.; Wojcik, S. M.; Martin, T. F. J.; Van der Sluijs, P.; Brose, N.; Gerke, V.: A novel Munc13-4/S100A10/Annexin A2 complex promotes Weibel-Palade body exocytosis in endothelial cells. Molecular Biology of the Cell 28 (12), pp. 1688 - 1700 (2017)

Jiang, C.; Kawabe, H.; Rotin, D.: The ubiquitin ligase Nedd4L regulates the Na/K/2Cl co-transporter NKCC1/SLC12A2 in the colon. The Journal of Biological Chemistry 292 (8), pp. 3137 - 3145 (2017)

Pei, G.; Buijze, H.; Liu, H.; Moura-Alves, P.; Goosmann, C.; Brinkmann, V.; Kawabe, H.; Dorhoi, A.; Kaufmann, S. H.E.: The E3 ubiquitin ligase NEDD4 enhances killing of membrane-perturbing intracellular bacteria by promoting autophagy. Autophagy 13 (12), pp. 2041 - 2055 (2017)

Schreiner, D.; Savas, J. N.; Herzog, E.; Brose, N.; de Wit, J.: Synapse biology in the 'circuit-age'-paths toward molecular connectomics. Current Opinion in Neurobiology 42, pp. 102 - 110 (2017)