Publications

Berg, L. J.; Lee, C. K.; Matsumura, H.; Leinhaas, A.; Konang, R.; Shaib, A. H.; Royero, P.; Schlee, J.; Sheng, C.; Beck, H. et al.; Schwarz, M. K.; Brose, N.; Rhee, J. S.; Brüstle, O.: Human neural stem cells directly programmed from peripheral blood show functional integration into the adult mouse brain. Stem Cell Research & Therapy 15, 488 (2024)

Altas, B.; Tuffy, L. P.; Patrizi, A.; Dimova, K.; Soykan, T.; Brandenburg, C.; Romanowski, A. J.; Whitten, J. R.; Robertson, C. D.; Khim, S. N. et al.; Crutcher, G. W.; Ambrozkiewicz, M.; Yagensky, O.; Krüger-Burg, D. D.; Hammer, M.; Hsiao, H.-H.; Laskowski, P. R.; Dyck, L.; Puche, A. C.; Sassoè-Pognetto, M.; Chua, J. J. E.; Urlaub, H.; Jahn, O.; Brose, N.; Poulopoulos, A.: Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory versus Inhibitory Synapses. Biological Psychiatry 96 (10), pp. 815 - 828 (2024)

Reshetniak, S.; Bogaciu, C. A.; Bonn, S.; Brose, N.; Cooper, B. H.; D'Este, E.; Fauth, M.; Fernández‐Busnadiego, R.; Fiosins, M.; Fischer, A. et al.; Georgiev, S. V.; Jakobs, S.; Klumpp, S.; Köster, S.; Lange, F.; Lipstein, N.; Macarrón‐Palacios, V.; Milovanovic, D.; Moser, T.; Müller, M.; Opazo, F.; Outeiro, T. F.; Pape, C.; Priesemann, V.; Rehling, P.; Salditt, T.; Schlüter, O.; Simeth, N.; Steinem, C.; Tchumatchenko, T.; Tetzlaff, C.; Tirard, M.; Urlaub, H.; Wichmann, C.; Wolf, F.; Rizzoli, S. O.: The synaptic vesicle cluster as a controller of pre‐ and postsynaptic structure and function. The Journal of Physiology (2024)

Zeppillo, T.; Ali, H.; Ravichandran, S.; Ritter, T. C.; Wenger, S.; López-Murcia, F. J.; Gideons, E.; Signorelli, J.; Schmeisser, M. J.; Wiltfang, J. et al.; Rhee, J. S.; Brose, N.; Taschenberger, H.; Krüger-Burg, D. D.: Functional Neuroligin-2-MDGA1 interactions differentially regulate synaptic GABA_ARs and cytosolic gephyrin aggregation. Communications Biology 7, 1157 (2024)

Asadollahi, E.; Trevisiol, A.; Saab, A. S.; Looser, Z. J.; Dibaj, P.; Ebrahimi, R.; Kusch, K.; Ruhwedel, T.; Möbius, W.; Jahn, O. et al.; Lee, J. Y.; Don, A. S.; Khalil, M.-A.; Hiller, K.; Baes, M.; Weber, B.; Abel, E. D.; Ballabio, A.; Popko, B.; Kassmann, C. M.; Ehrenreich, H.; Hirrlinger, J.; Nave, K.-A.: Oligodendroglial fatty acid metabolism as a central nervous system energy reserve. Nature Neuroscience 27, pp. 1934 - 1944 (2024)

Jeong, S.; Lee, B.-Y.; Rhee, J. S.; Lee, J.-H.: G protein β subunits regulate Ca_v3.3 T-type channel activity and current kinetics via interaction with the Ca_v3.3 C-terminus. Biochimica et Biophysica Acta: BBA 1866 (6), 184337 (2024)

Blackburn, D. M.; Sahinyan, K.; Hernández-Corchado, A.; Lazure, F.; Richard, V.; Raco, L.; Perron, G.; Zahedi, R. P.; Borchers, C. H.; Lepper, C. et al.; Kawabe, H.; Jahani-Asl, A.; Najafabadi, H. S.; Soleimani, V. D.: The E3 ubiquitin ligase Nedd4L preserves skeletal muscle stem cell quiescence by inhibiting their activation. iScience 27 (7), 110241 (2024)

Flores-Hermenegildo, J. M.; Hernández-Cázares, F. d. J.; Pérez-Pérez, D.; Romero-Ramírez, H.; Rodríguez-Alba, J. C.; Licona-Limon, P.; Kilimann, M. W.; Santos-Argumedo, L.; López-Herrera, G.: Lrba participates in the differentiation of IgA plus B lymphocytes through TGFβR signaling. Frontiers in Immunology 15, 1386260 (2024)

Day, J.; Tirard, M.; Brose, N.: Deletion of a core APC/C component reveals APC/C function in regulating neuronal USP1 levels and morphology. Frontiers in Molecular Neuroscience 17, 1352782 (2024)

Borisova, E.; Newman, A. G.; Couce Iglesias, M.; Dannenberg, R.; Schaub, T.; Qin, B.; Rusanova, A.; Brockmann, M.; Koch, J.; Daniels, M. et al.; Turko, P.; Jahn, O.; Kaplan, D. R.; Rosário, M.; Iwawaki, T.; Spahn, C. M. T.; Rosenmund, C.; Meierhofer, D.; Kraushar, M. L.; Tarabykin, V.; Ambrozkiewicz, M. C.: Protein translation rate determines neocortical neuron fate. Nature Communications 15, 4879 (2024)

Wirths, O.; Lehnen, C.; Fricke, M.; Talucci, I.; Klafki, H.-W.; Morgado, B.; Lehmann, S.; Münch, C.; Liepold, T.; Wiltfang, J. et al.; Rostagno, A.; Ghiso, J.; Maric, H. M.; Jahn, O.; Weggen, S.: Amino-terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4 and deposit in a subset of Alzheimer's disease brains. Neuropathology and Applied Neurobiology 50 (3), e12991 (2024)

Roussa, E.; Juda, P.; Laue, M.; Mai-Kolerus, O.; Meyerhof, W.; Sjoeblom, M.; Nikolovska, K.; Seidler, U.; Kilimann, M. W.: LRBA, a BEACH protein mutated in human immune deficiency, is widely expressed in epithelia, exocrine and endocrine glands, and neurons. Scientific Reports 14, 10678 (2024)

Giusti, S. A.; Pino, N. S.; Pannunzio, C.; Ogando, M. B.; Armando, N. G.; Garrett, L.; Zimprich, A.; Becker, L.; Gimeno, M. L.; Lukin, J. et al.; Merino, F. L.; Pardi, M. B.; Pedroncini, O.; Di Mauro, G. C.; Durner, V. G.; Fuchs, H.; de Angelis, M. H.; Patop, I. L.; Turck, C. W.; Deussing, J. M.; Vogt Weisenhorn, D. M.; Jahn, O.; Kadener, S.; Hölter, S. M.; Brose, N.; Giesert, F.; Wurst, W.; Marin-Burgin, A.; Refojo, D.: A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli. Science Advances 10 (21), eadj8769 (2024)

López-Murcia, F. J.; Lin, K.-H.; Berns, M. M. M.; Ranjan, M.; Lipstein, N.; Neher, E.; Brose, N.; Reim, K.; Taschenberger, H.: Complexin has a dual synaptic function as checkpoint protein in vesicle priming and as a promoter of vesicle fusion. PNAS 121 (15), e2320505121 (2024)

Chen, H.; Monga, M.; Fang, Q.; Slitin, L.; Neef, J.; Chepurwar, S. S.; Netto, R. C. M.; Lezirovitz, K.; Tabith Jr, A.; Benseler, F. et al.; Brose, N.; Kusch, K.; Wichmann, C.; Strenzke, N.; Vona, B.; Preobraschenski, J.; Moser, T.: Ca²⁺ binding to the C₂E domain of otoferlin is required for hair cell exocytosis and hearing. Protein & Cell 15 (4), pp. 305 - 312 (2024)

Lux, U. T.; Meyer, J.; Jahn, O.; Davison, A.; Babai, N.; Gießl, A.; Wartenberg, A.; Sticht, H.; Brose, N.; Reim, K. et al.; Brandstätter, J. H.: Light-dependent regulation of neurotransmitter release from rod photoreceptor ribbon synapses involves an interplay of Complexin 4 and Transducin with the SNARE complex. Frontiers in Molecular Neuroscience 17, 1308466 (2024)

Koppensteiner, P.; Bhandari, P.; Önal, C.; Borges-Merjane, C.; Le Monnier, E.; Roy, U.; Nakamura, Y.; Sadakata, T.; Sanbo, M.; Hirabayashi, M. et al.; Rhee, J. S.; Brose, N.; Jonas, P.; Shigemoto, R.: GABA_B receptors induce phasic release from medial habenula terminals through activity-dependent recruitment of release-ready vesicles. PNAS 121 (8), e2301449121 (2024)

Clavet-Fournier, V.; Lee, C.; Wegner, W.; Brose, N.; Rhee, J. S.; Willig, K. I.; Rhee, J. S.: Pre- and postsynaptic nanostructures increase in size and complexity after induction of long-term potentiation. iScience 27 (1), 108679 (2024)

Altas, B.; Rhee, H. J.; Ju, A.; Solis, H. C.; Karaca, S.; Winchenbach, J.; Kaplan-Arabaci, O.; Schwark, M.; Ambrozkiewicz, M.; Lee, C. et al.; Spieth, L.; Wieser, G. L.; Chaugule, V. K.; Majoul, I.; Hassan, M. A.; Goel, R.; Wojcik, S. M.; Koganezawa, N.; Hanamura, K.; Rotin, D.; Pichler, A.; Mitkovski, M.; de Hoz, L.; Poulopoulos, A.; Urlaub, H.; Jahn, O.; Saher, G.; Brose, N.; Rhee, J.; Kawabe, H.: Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity. Journal of Cell Biology 223 (1), e201902050 (2024)

Kim, O.; Okamoto, Y.; Kaufmann, W.A.; Brose, N.; Shigemoto, R.; Jonas, P.: Presynaptic cAMP-PKA-mediated potentiation induces reconfiguration of synaptic vesicle pools and channel-vesicle coupling at hippocampal mossy fiber boutons. PLOS Biology 22 (11), e3002879 (2024)

Paulke, N. J.; Fleischhacker, C.; Wegener, J. B.; Riedemann, G. C.; Cretu, C.; Mushtaq, M.; Zaremba, N.; Möbius, W.; Zühlke, Y.; Wedemeyer, J. et al.; Liebmann, L.; Gorshkova, A. A.; Kownatzki-Danger, D.; Wagner, E.; Kohl, T.; Wichmann, C.; Jahn, O.; Urlaub, H.; Toischer, K.; Hasenfuß, G.; Moser, T.; Preobraschenski, J.; Lenz, C.; Rog-Zielinska, E. A.; Lehnart, S. E.; Brandenburg, S.: Dysferlin Enables Tubular Membrane Proliferation in Cardiac Hypertrophy. Circulation Research 135 (5), pp. 554 - 574 (2024)