Publications of D. Haselbach
All genres
Journal Article (10)
2019
Journal Article
116 (35), pp. 17280 - 17289 (2019)
Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site. Proceedings of the National Academy of Sciences of the United States of America 2018
Journal Article
172 (3), pp. 454 - 464, e1-e5 (2018)
Structure and conformational dynamics of the human spliceosomal Bact complex. Cell 2017
Journal Article
170 (4), pp. 701 - 713, e1 - e4 (2017)
Cryo-EM structure of a pre-catalytic human spliceosome primed for activation. Cell
Journal Article
8, 15578 (2017)
Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nature Communications 2016
Journal Article
63 (4), pp. 593 - 607 (2016)
Cryo-EM of mitotic checkpoint complex-bound APC/C reveals reciprocal and conformational regulation of ubiquitin ligation. Molecular Cell
Journal Article
165 (6), pp. 1440 - 1453 (2016)
Dual RING E3 architectures regulate multiubiquitination and ubiquitin chain elongation by APC/C. Cell
Journal Article
113 (19), pp. E2570 - E2578 (2016)
Mechanism of APC/C-CDC20 activation by mitotic phosphorylation. Proceedings of the National Academy of Sciences of the United States of America 2015
Journal Article
12 (9), pp. 859 - 865 (2015)
ProteoPlex: Stability optimization of macromolecular complexes by sparse-matrix screening of chemical space. Nature Methods 2013
Journal Article
21 (8), pp. 1350 - 1360 (2013)
Structural determinants and mechanism of mammalian CRM1 allostery. Structure
Journal Article
110 (3), pp. 960 - 965 (2013)
Structural basis for cooperativity of CRM1 export complex formation. Proceedings of the National Academy of Sciences of the United States of America Conference Paper (1)
2013
Conference Paper
104 (Supplement 1), 2 Ed., p. 68A - 68A (2013)
Structural determinants of conformational flexibility and long-range allostery of the CRM1 export complex. 57th Annual Meeting of the Biophysical-Society, Philadelphia/PA, February 02, 2013 - February 06, 2013. Biophysical Journal Thesis - PhD (1)
2014
Thesis - PhD
Conformational dynamics of large proteins and protein complexes. Dissertation, Georg-August-Universität, Göttingen (2014)