Publications of Marcelo Ganzella

Preobraschenski, J.; Kreutzberger, A. J. B.; Ganzella, M.; Münster-Wandowski, A.; Kreutzberger, M. A. B.; Oolsthorn, L. H. M.; Seibert, S.; Kiessling, V.; Riedel, D.; Witkowska, A. et al.; Ahnert-Hilger, G.; Tamm, L. K.; Jahn, R.: Synaptophysin accelerates synaptic vesicle fusion by expanding the membrane upon neurotransmitter loading. Science Advances 11 (17), eads4661 (2025)

Neuhaus, C.; Alfken, J.; Frost, J.; Matthews, L.; Hoffmann, C.; Ganzella, M.; Milovanovic, D.; Salditt, T.: Morphology and intervesicle distances in condensates of synaptic vesicles and synapsin. Biophysical Journal 123 (23), pp. 4123 - 4134 (2024)

Qiu, H.; Wu, X.; Ma, X.; Li, S.; Cai, Q.; Ganzella, M.; Ge, L.; Zhang, H.; Zhang, M.: Short-distance vesicle transport via phase separation. Cell 187 (9), pp. 2175 - 2193.e21 (2024)

Alfken, J.; Neuhaus, C.; Major, A.; Taskina, A.; Hoffmann, C.; Ganzella, M.; Petrovic, A.; Zwicker, D.; Fernández-Busnadiego, R.; Jahn, R. et al.; Milovanovic, D.; Salditt, T.: Vesicle condensation induced by synapsin: condensate size, geometry, and vesicle shape deformations. European Physical Journal E 47 (1), 8 (2024)

Binotti, B.; Ninov, M.; Cepeda, A. P.; Ganzella, M.; Matti, U.; Riedel, D.; Urlaub, H.; Sambandan, S.; Jahn, R.: ATG9 resides on a unique population of small vesicles in presynaptic nerve terminals. Autophagy 20 (4), pp. 883 - 901 (2024)

Hoffmann, C.; Rentsch, J.; Tsunoyama, T.A.; Chhabra, A.; Aguilar Perez, G.; Chowdhury, R.; Trnka, F.; Korobeinikov, A.A.; Shaib, A.H.; Ganzella, M. et al.; Giannone, G.; Rizzoli, S.O.; Kusumi, A.; Ewers, H.; Milovanovic, D.: Synapsin condensation controls synaptic vesicle sequestering and dynamics. Nature Communications 14 (1), 6730 (2023)

Kosmidis, E.; Shuttle, C. G.; Preobraschenski, J.; Ganzella, M.; Johnson, P. J.; Veshaguri, S.; Holmkvist, J.; Moller, M. P.; Marantos, O.; Marcoline, F. et al.; Grabe, M.; Pedersen, J. L.; Jahn, R.; Stamou, D.: Regulation of the mammalian-brain V-ATPase through ultraslow mode-switching. Nature 611 (7937), pp. 827 - 834 (2022)

Birinci, Y.; Preobraschenski, J.; Ganzella, M.; Jahn, R.; Park, Y.: Author Correction: Isolation of large dense-core vesicles from bovine adrenal medulla for functional studies. Scientific Reports 12, 16738 (2022)

Komorowski, K.; Preobraschenski, J.; Ganzella, M.; Alfken, J.; Neuhaus, C.; Jahn, R.; Salditt, T.: Neurotransmitter uptake of synaptic vesicles studied by X-ray diffraction. European Biophysics Journal 51, pp. 465 - 482 (2022)

Upmanyu, N.; Jin, J.; von der Emde, H.; Ganzella, M.; Bösche, L.; Malviya, V. N.; Zhuleku, E.; Politi, A. Z.; Ninov, M.; Silbern, I. et al.; Leutenegger, M.; Urlaub, H.; Riedel, D.; Preobraschenski, J.; Milosevic, I.; Hell, S. W.; Jahn, R.; Sambandan, S.: Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3. Neuron 110 (9), pp. 1483 - 1497 (2022)

Wittig, S.; Ganzella, M.; Kostmann, S.; Barth, M.; Riedel, D.; Perez-Lara, A.; Jahn, R.; Schmidt, C.: Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes. Nature Communications 12, 858 (2021)

Wu, X.; Ganzella, M.; Zhou, J.; Zhu, S.; Jahn, R.; Zhang, M.: Vesicle tethering on the surface of phase-separated active zone condensates. Molecular Cell 81 (1), pp. 13 - 24.e7 (2021)

Birinci, Y.; Preobraschenski, J.; Ganzella, M.; Jahn, R.; Park, Y.: Isolation of large dense-core vesicles from bovine adrenal medulla for functional studies. Scientific Reports 10, 7540 (2020)

Preobraschenski, J.; Chere, C.; Ganzella, M.; Zander, J. F.; Richter, K.; Schenck, S.; Jahn, R.; Ahnert-Hilger, G.: Dual and direction-selective mechanisms of phosphate transport by the vesicular glutamate transporter. Cell Reports 23 (2), pp. 535 - 545 (2018)

Lanznaster, D.; Mack, J. M.; Coelho, V.; Ganzella, M.; Almeida, R. F.; Dal-Cim, T.; Hansel, G.; Zimmer, E. R.; Souza, D. O.; Prediger, R. D. et al.; Tasca, C. I.: Guanosine prevents anhedonic-like behavior and impairment in hippocampal glutamate transport following amyloid-β_1–40 administration in mice. Molecular Neurobiology 54 (7), pp. 5482 - 5496 (2017)

de Almeida, R. F.; Ganzella, M.; Machado, D. G.; Loureiro, S. O.; Leffa, D.; Quincozes-Santos, A.; Pettenuzzo, L. F.; Duarte, M. M. M. F.; Duarte, T.; Souza, D. O.: Olfactory bulbectomy in mice triggers transient and long-lasting behavioral impairments and biochemical hippocampal disturbances. Progress in Neuro-Psychopharmacology and Biological Psychiatry 76, pp. 1 - 11 (2017)

Almeida, R. F.; Comasseto, D. D.; Ramos, D. B.; Hansel, G.; Zimmer, E. R.; Loureiro, S. O.; Ganzella, M.; Souza, D. O.: Guanosine anxiolytic-like effect involves adenosinergic and glutamatergic neurotransmitter systems. Molecular Neurobiology 54 (1), pp. 423 - 436 (2017)

Ramos, D. B.; Muller, G. C.; Rocha, G. B. M.; Dellavia, G. H.; Almeida, R. F.; Pettenuzzo, L. F.; Loureiro, S. O.; Hansel, G.; Horn, A. C. M.; Souza, D. O. et al.; Ganzella, M.: Intranasal guanosine administration presents a wide therapeutic time window to reduce brain damage induced by permanent ischemia in rats. Purinergic Signalling 12 (1), pp. 149 - 159 (2016)

Brandão-Teles, C.; Zuccoli, G.S.; Ganzella, M.; Corasolla Carregari, V.; Olsthoorn, L.; de Almeida Duque, É.; Munhoz, C.D.; Jahn, R.; Martins-de-Souza, D.; Crunfli, F.: Isolating Synaptic Vesicles from Neurospheres for Proteomics. In: Tissue Proteomics: Methods and Protocols, pp. 207 - 223 (Ed. Williams, T. I.). Humana Press, New York, NY (2025)

Müller, G. C.; Loureiro, S. O.; Almeida, R. F.; Pettenuzzo, L. F.; Ganzella, M.; Souza, D. O.: Neuroprotective effects of intranasal Guanosine: Wide theurapeutic window and a possible mechanism. 28th International Symposium on Cerebral Blood Flow, Metabolism and Function / 13th International Conference on Quantification of Brain Function with PET, Berlin, Germany, April 01, 2017 - April 04, 2017. Journal of Cerebral Blood Flow and Metabolism 37 (Suppl 1), pp. 111 - 112 (2017)