Publications of P. Cramer

Sainsbury, S.; Bernecky, C.; Cramer, P.: Structural basis of transcription initiation by RNA polymerase II. Nature Reviews Molecular Cell Biology 16 (3), pp. 129 - 143 (2015)

Plaschka, C.; Larivière, L.; Wenzeck, L.; Seizl, M.; Hemann, M.; Tegunov, D.; Petrotchenko, E. V.; Borchers, C. H.; Baumeister, W.; Herzog, F. et al.; Villa, E.; Cramer, P.: Architecture of the RNA polymerase II–Mediator core initiation complex. Nature 518 (7539), pp. 376 - 380 (2015)

Borck, G.; Hög, F.; Dentici, M. L.; Tan, P. L.; Sowada, N.; Medeira, A.; Gueneau, L.; Thiele, H.; Kousi, M.; Lepri, F. et al.; Wenzeck, L.; Blumenthal, I.; Radicioni, A.; Schwarzenberg, T. L.; Mandriani, B.; Fischetto, R.; Morris-Rosendahl, D. J.; Altmüller, J.; Reymond, A.; Nürnberg, P.; Merla, G.; Dallapiccola, B.; Katsanis, N.; Cramer, P.; Kubisch, C.: BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies. Genome Research 25 (2), pp. 155 - 166 (2015)

Zacher, B.; Lidschreiber, M.; Cramer, P.; Gagneur, J.; Tresch, A.: Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle. Molecular Systems Biology 10 (12), 768 (2014)

Cramer, P.: A tale of chromatin and transcription in 100 structures. Cell 159 (5), pp. 985 - 994 (2014)

Bäjen, C.; Torkler, P.; Gressel, S.; Essig, K.; Söding, J.; Cramer, P.: Transcriptome maps of mRNP biogenesis factors define pre-mRNA recognition. Molecular Cell 55 (5), pp. 745 - 757 (2014)

Tudek, A.; Porrua, O.; Kabzinski, T.; Lidschreiber, M.; Kubicek, K.; Fortova, A.; Lacroute, F.; Vanakova, S.; Cramer, P.; Stefl, R. et al.; Libri, D.: Molecular basis for coordinating transcription termination with noncoding RNA degradation. Molecular Cell 55 (3), pp. 467 - 481 (2014)

Mühlbacher, W.; Sainsbury, S.; Hemann, M.; Hantsche, M.; Neyer, S.; Herzog, F.; Cramer, P.: Conserved architecture of the core RNA polymerase II initiation complex. Nature Communications 5, 4310 (2014)

Sydow, J. F.; Lipsmeier, F.; Larraillet, V.; Hilger, M.; Mautz, B.; Mølhøj, M.; Kuentzer, J.; Klostermann, S.; Schoch, J.; Voelger, H. R. et al.; Regula, J. T.; Cramer, P.; Papadimitriou, A.; Kettenberger, H.: Structure-based prediction of asparagine and aspartate degradation sites in antibody variable regions. PLoS One 9 (6), e100736 (2014)

Schulz, D.; Pirkl, N.; Lehmann, E.; Cramer, P.: Rpb4 functions mainly in mRNA synthesis by RNA polymerase II. Journal of Biological Chemistry 289 (25), pp. 17446 - 17452 (2014)

Hirschmann, W. D.; Westendorf, H.; Mayer, A.; Cannarozzi, G.; Cramer, P.; Jansen, R. P.: Scp160p is required for translational efficiency of codon-optimized mRNAs in yeast. Nucleic Acids Research 42 (6), pp. 4043 - 4055 (2014)

Morozov, Y. I.; Agaronyan, K.; Cheung, A. C. M.; Anikin, M.; Cramer, P.; Temiakov, D.: A novel intermediate in transcription initiation by human mitochondrial RNA polymerase. Nucleic Acids Research 42 (6), pp. 3884 - 3893 (2014)

Schreieck, A.; Easter, A. D.; Etzold, S.; Wiederhold, K.; Lidschreiber, M.; Cramer, P.; Passmore, L. A.: RNA polymerase II termination involves C-terminal-domain tyrosine dephosphorylation by CPF subunit Glc7. Nature Structural and Molecular Biology 21 (2), pp. 175 - 179 (2014)

Eser, P.; Demel, C.; Maier, K. C.; Schwalb, B.; Pirkl, N.; Martin, D. E.; Cramer, P.; Tresch, A.: Periodic mRNA synthesis and degradation co-operate during cell cycle gene expression. Molecular Systems Biology 10 (1), 717 (2014)

Meinel, D. M.; Burkert-Kautzsch, C.; Kieser, A.; O'Duibhir, E.; Siebert, M.; Mayer, A.; Cramer, P.; Söding, J.; Holstege, F. C.; Sträßer, K.: Recruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II. PLoS Genetics 9 (11), e1003914 (2013)

Schulz, D.; Schwalb, B.; Kiesel, A.; Baejen, C.; Torkler, P.; Gagneur, J.; Söding, J.; Cramer, P.: Transcriptome surveillance by selective termination of noncoding RNA synthesis. Cell 155 (5), pp. 1075 - 1087 (2013)

Heo, D.-h.; Yoo, I.; Kong, J.; Lidschreiber, M.; Mayer, A.; Choi, B.-Y.; Hahn, Y.; Cramer, P.; Buratowski, S.; Kim, M.: The RNA polymerase II C-terminal domain-interacting domain of yeast Nrd1 contributes to the choice of termination pathway and couples to RNA processing by the nuclear exosome. Journal of Biological Chemistry 288 (51), pp. 36676 - 36690 (2013)

Engel, C.; Sainsbury, S.; Cheung, A. C.; Kostrewa, D.; Cramer, P.: RNA polymerase I structure and transcription regulation. Nature 502 (7473), pp. 650 - 655 (2013)

Sun, M.; Schwalb, B.; Pirkl, N.; Maier, K. C.; Schenk, A.; Failmezger, H.; Tresch, A.; Cramer, P.: Global analysis of eukaryotic mRNA degradation reveals Xrn1-dependent buffering of transcript levels. Molecular cell 52 (1), pp. 52 - 62 (2013)

Schwinghammer, K.; Cheung, A. C. M.; Morozov, Y. I.; Agaronyan, K.; Temiakov, D.; Cramer, P.: Structure of human mitochondrial RNA polymerase elongation complex. Nature Structural and Molecular Biology 20 (11), pp. 1298 - 1303 (2013)