Publications of A. Leonov

Jaipuria, G.; Leonov, A.; Giller, K.; Vasa, S. K.; Jaremko, Ł.; Jaremko, M.; Linser, R.; Becker, S.; Zweckstetter, M.: Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure. Nature Communications 8, 14893 (2017)

Fellner, L.; Kuzdas-Wood, D.; Levin, J.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.; Wenning, G. K.; Stefanova, N.: Anle138b partly ameliorates motor deficits despite failure of neuroprotection in a model of advanced multiple system atrophy. Frontiers in Neuroscience 10, 99 (2016)

Wagner, J.; Krauss, S.; Shi, S.; Ryazanov, S.; Steffen, J.; Miklitz, C.; Leonov, A.; Kleinknecht, A.; Göricke, B.; Weishaupt, J. H. et al.; Weckbecker, D.; Reiner, A. M.; Zinth, W.; Levin, J.; Ehninger, D.; Remy, S.; Kretzschmar, H. A.; Griesinger, C.; Giese, A.; Fuhrmann, M.: Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies. Acta Neuropathologica 130 (5), pp. 619 - 631 (2015)

Deeg, A. A.; Reiner, A. M.; Schmidt, F.; Schueder, F.; Ryazanov, S.; Ruf, V. C.; Giller, K.; Becker, S.; Leonov, A.; Griesinger, C. et al.; Giese, A.; Zinth, W.: Anle138b and related compounds are aggregation specific fluorescence markers and reveal high affinity binding to α-synuclein aggregates. Biochimica et Biophysica Acta-General Subjects 1850 (9), pp. 1884 - 1890 (2015)

Shi, S.; Wagner, J.; Mitteregger-Kretzschmar, G.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.: Quantitative real-time quaking-induced conversion allows monitoring of disease-modifying therapy in the urine of prion-infected mice. Journal of Neuropathology and Experimental Neurology 74 (9), pp. 924 - 933 (2015)

Levin, J.; Schmidt, F.; Boehm, C.; Prix, C.; Bötzel, K.; Ryazanov, S.; Leonov, A.; Griesinger, C.; Giese, A.: The oligomer modulator anle138b inhibits disease progression in a Parkinson mouse model even with treatment started after disease onset. Acta Neuropathologica 127 (5), pp. 779 - 780 (2014)

Schützenmeister, N.; Müller , M.; Reinscheid, U. M.; Griesinger, C.; Leonov, A.: Trapped in misbelief for almost 40 years: Selective synthesis of the four stereoisomers of mefloquine. Chemistry 19 (51), pp. 17584 - 17588 (2013)

Wagner, J.; Ryazanov, S.; Leonov, A.; Levin, J.; Shi, S.; Schmidt, F.; Prix, C.; Pan-Montojo, F.; Bertsch, U.; Mitteregger-Kretzschmar, G. et al.; Geissen, M.; Eiden, M.; Leidel, F.; Hirschberger, T.; Deeg, A. A.; Krauth, J.; Zinth, W.; Tavan, P.; Pilger, J.; Zweckstetter, M.; Frank, T.; Baehr, M.; Weishaupt, J. H.; Uhr, M.; Urlaub, H.; Teichmann, U.; Samwer, M.; Bötzel, K.; Groschup, M.; Kretzschmar, H.; Griesinger, C.; Giese, A.: Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Acta Neuropathologica 125 (6), pp. 795 - 813 (2013)

Müller , M.; Orben, C. M.; Schützenmeister, N.; Schmidt, M.; Leonov, A.; Reinscheid, U. M.; Dittrich, B.; Griesinger, C.: The absolute configuration of (+)- and (-)-erythro-mefloquine. Angewandte Chemie International Edition 52 (23), pp. 6047 - 6049 (2013)

Schmidt, M.; Sun, H.; Leonov, A.; Griesinger, C.; Reinscheid, U. M.: Chiral discrimination of amines by anisotropic NMR parameters using chiral polyacrylamide-based gels. Magnetic Resonance in Chemistry 50 (Supplement 1), pp. S38 - S44 (2012)

Peters, F.; Maestre-Martinez, M.; Leonov, A.; Kovacic, L.; Becker, S.; Boelens, R.; Griesinger, C.: Cys-Ph-TAHA: A lanthanide binding tag for RDC and PCS enhanced protein NMR. Journal of Biomolecular NMR 51 (3), pp. 329 - 337 (2011)

Erdelyi, M.; d'Auvergne, E.; Navarro-Vazquez, A.; Leonov, A.; Griesinger, C.: Dynamics of the glycosidic bond: Conformational space of lactose. Chemistry: A European Journal 17 (34), pp. 9368 - 9376 (2011)

Krahn, A.; Lottmann, P.; Marquardsen, T.; Tavernier, A.; Tuerke, M. T.; Reese, M.; Leonov, A.; Bennati, M.; Hoefer, P.; Engelke, F. et al.; Griesinger, C.: Shuttle DNP spectrometer with a two-center magnet. Physical Chemistry Chemical Physics 12 (22), pp. 5830 - 5840 (2010)

Montaville, P.; Condevylle, N.; Radhakrishnan, A.; Leonov, A.; Zweckstetter, M.; Becker, S.: The PIP2 binding mode of the C2 domains of rabphilin-3A. Protein Science 17 (6), pp. 1025 - 1034 (2008)

Schuetz, A.; Junker, J.; Leonov, A.; Lange, O.; Molinski, T. F.; Griesinger, C.: Stereochemistry of sagittamide a from residual dipolar coupling enhanced NMR. Journal of the American Chemical Society 129 (49), pp. 15114 - 15115 (2007)

Montaville, P.; Schlicker, C.; Leonov, A.; Zweckstetter, M.; Sheldrick, G. M.; Becker, S.: The C2A-C2B linker defines the high affinity Ca2⁺ binding mode of rabphilin-3A. Journal of Biological Chemistry 282 (7), pp. 5015 - 5025 (2007)

Rodriguez-Castaneda, F.; Haberz, P.; Leonov, A.; Griesinger, C.: Paramagnetic tagging of diamagnetic proteins for solution NMR. Magnetic Resonance in Chemistry 44 (Sp. Iss. S1), pp. S10 - S16 (2006)

Haberz, P.; Rodriguez-Castaneda, F.; Junker, J.; Becker, S.; Leonov, A.; Griesinger, C.: Two new chiral EDTA-based metal chelates for weak alignment of proteins in solution. Organic Letters 8 (7), pp. 1275 - 1278 (2006)

Leonov, A.; Voigt, B.; Rodriguez-Castaneda, F.; Sakhaii, P.; Griesinger, C.: Convenient synthesis of multifunctional EDTA-based chiral metal chelates substituted with an S-mesylcysteine. Chemistry-A European Journal 11 (11), pp. 3342 - 3348 (2005)

Buss, S.; Kuebler, L.; Maurer, A.; Schmidt, F.; Leonov, A.; Ryazanov, S.; Giese, A.; Griesinger, C.; Pichler, B. J.; Herfert, K.: In vitro evaluation of small molecule compounds as potential PET tracers targeting a-synuclein. 29th International Symposium on Cerebral Blood Flow, Metabolism and Function / 14th International Conference on Quantification of Brain Function with PET (BRAIN and BRAIN Pet), Yokohama, Japan, July 04, 2019 - July 07, 2019. Journal of Cerebral Blood Flow and Metabolism 39 (Suppl), pp. 530 - 531 (2019)