Publications of S. Wacker

Wacker, S.; Aponte-Santamaria, C. A.; Kjellbom, P.; Nielsen, S.; de Groot, B. L.; Rützler, M.: The identification of novel, high affinity AQP9 inhibitors in an intracellular binding site. Molecular Membrane Biology 30 (3), pp. 246 - 260 (2013)

Wacker, S. J.; Jurkowski, W.; Simmons, K. J.; Fishwick, C. W. G.; Johnson, A. P.; Madge, D.; Lindahl, E.; Rolland, J. F.; de Groot, B. L.: Identification of selective inhibitors of the potassium channel Kv1.1–1.2(3) by high-throughput virtual screening and automated patch clamp. ChemMedChem 7 (10), pp. 1775 - 1783 (2012)

Jelen, S.; Wacker, S.; Aponte-Santamaria, C. A.; Skott, M.; Rojek, A.; Johanson, U.; Kjellbom, P.; Nielsen, S.; de Groot, B. L.; Ruetzler, M.: Aquaporin-9 protein is the primary route of hepatocyte glycerol uptake for glycerol gluconeogenesis in mice. Journal of Biological Chemistry 286 (52), pp. 44319 - 44325 (2011)

Stary, A.; Wacker, S.; Boukharta, L.; Zachariae, U.; Karimi-Nejad, Y.; Aqvist, J.; Vriend, G.; de Groot, B. L.: Toward a consensus model of the hERG potassium channel. ChemMedChem 5 (3), pp. 455 - 467 (2010)

Zachariae, U.; Schneider, R.; Velisetty, P.; Lange, A.; Seeliger, D.; Wacker, S.; Karimi-Nejad, J.; Vriend, G.; Becker, S.; Pongs, O. et al.; Baldus, M.; de Groot, B. L.: The molecular mechanism of toxin-induced conformational changes in a potassium channel: relation to C-type inactivation. Structure 16 (5), pp. 747 - 754 (2008)

Valiente, P. A.; Wolf, M. G.; Guerra, Y.; Sierra, Y.; Wacker, S.; Pascual, I.; Pons, T.; Groenhof, G.: Use of principal component analysis and molecular docking to identify novel selective plasmepsin II inhibitors. In FEBS Journal, 279 (Supplement 1), p. 447 - 447. 22nd IUBMB Congress/37th FEBS Congress, Seville/Spain, September 04, 2012 - September 09, 2012. (2012)

Wacker, S.: Computer-aided drug design for membrane channel proteins. Dissertation, XVIII, 147 pp., Georg-August-Universität, Göttingen (2012)

Wacker, S.: Molecular dynamics study of potassium channels, thier interaction with non-amino acid compounds and peptidic scorpion toxins. Diploma, Universität Göttingen, Göttingen (2008)