Publications of R. Klement

Hett, T.; Zbik, T.; Mukherjee, S.; Matsuoka, H.; Bönigk, W.; Klose, D.; Rouillon, C.; Brenner, N.; Peuker, S.; Klement, R. et al.; Steinhoff, H.-J.; Grubmüller, H.; Seifert, R.; Schiemann, O.; Kaupp, U. B.: Spatiotemporal resolution of conformational changes in biomolecules by combining pulsed electron–electron double resonance spectroscopy with microsecond freeze-hyperquenching. Journal of the American Chemical Society 143 (18), pp. 6981 - 6989 (2021)

Graen, T.; Klement, R.; Grupi, A.; Haas, E.; Grubmüller, H.: Transient secondary and tertiary structure formation kinetics in the intrinsically disordered state of α-Synuclein from atomistic simulations. ChemPhysChem 19 (19), pp. 2507 - 2511 (2018)

Ziomkiewicz, I.; Loman, A.; Klement, R.; Fritsch, C.; Klymchenko, A.; Bunt, G.; Jovin, T. M.; Arndt-Jovin, D. J.: Dynamic conformational transitions of the EGF receptor in living mammalian cells determined by FRET and fluorescence lifetime imaging microscopy. Cytrometry A 83 (9), pp. 794 - 805 (2013)

Roberti, M. J.; Bertoncini, C. W.; Klement, R.; Jares-Erijman, E. A.; Jovin, T. M.: Fluorescence imaging of amyloid formation in living cells by a functional, tetracysteine-tagged alpha-synuclein. Nature Methods 4 (4), pp. 345 - 351 (2007)

Cojocaru, V.; Klement, R.; Jovin, T. M.: Loss of G-A base pairs is insufficient for achieving a large opening of U4 snRNA K-turn motif. Nucleic Acids Research 33 (10), doi:10.1093/nar/gki664, pp. 3435 - 3446 (2005)

Alexopoulos, E.; Jares-Erijman, E. A.; Jovin, T. M.; Klement, R.; Sheldrick, G. M.; Uson, I.: Crystal and solution structures of 7-amino-actinomycin D complexes with d(TTAGBrUT), d(TTAGTT) and d(TTTAGTTT). Acta Crystallographica D 61, doi:10.1107/S090744490500082X, pp. 407 - 415 (2005)

Cojocaru, V.; Nottrott, S.; Klement, R.; Jovin, T. M.: The snRNP 15.5K protein folds its cognate K-turn RNA. A combined theoretical and biochemical study. RNA 11 (2), 10.1261/rna.7149605, pp. 197 - 209 (2005)

Geingenaud, F.; Mondragon-Sanchez, J. A.; Liquier, J.; Shchyolkina, A. K.; Klement, R.; Arndt-Jovin, D. J.; Jovin, T. M.; Tallandier, E.: Parallel DNA double helices incorporating isoG or m⁵ isoC bases studied by FTIR, CD and molecular modeling. Spectrochimica Acta A 61, doi:10.1016/j.saa.2004.05.037, pp. 579 - 587 (2005)

Shchyolkina, A. K.; Borisova, O. F.; Livshits, M. A.; Klement, R.; Jovin, T. M.: The telomeric dG(GT)4G sequence can adopt a parallel-stranded double helical conformation. Journal of Biomolecular Structure and Dynamics 18, pp. 493 - 503 (2001)

Shchyolkina, A. K.; Borisova, O. F.; Livshits, M. A.; Pozmogova, G. E.; Chernov, B. K.; Klement, R.; Jovin, T. M.: Parallel-stranded DNA with mixed AT/GC composition: role of trans G·C base pairs in sequence dependent helical stability. Biochemistry 39, doi:10.1021/bi9913909, pp. 10034 - 10044 (2000)

Mohammadi, S.; Klement, R.; Shchyolkina, A. K.; Liquier, J.; Jovin, T. M.; Tallandier, E.: FTIR and UV spectroscopy of parallel-stranded DNAs with mixed A·T/G·C sequences and their inosine analogs. Biochemistry 37, pp. 16529 - 16537 (1998)

Shchyolkina, A. K.; Minchenkova, L. E.; Minyat, E. E.; Khomyakova, Y. B.; Ivanov, V. I.; Klement, R.; Jovin, T. M.: Distamycin-stabilized antiparallel-parallel-combination (APC) DNA. Journal of Biomolecular Structure and Dynamics 15, pp. 823 - 839 (1998)

Jares-Erijman, E. A.; Klement, R.; Machinek, R.; Wadkins, R. M.; Kankia, B. I.; Marky, L. A.; Jovin, T. M.: Binding of actinomycin D to single-stranded DNA. Nucleosides & Nucleotides 16 (5-6), pp. 661 - 667 (1997)

Wadkins, R. M.; Jares-Erijman, E. A.; Klement, R.; Rudiger, A.; Jovin, T. M.: Actinomycin D binding to single-stranded DNA: Sequence specificity and hemi-intercalation model from fluorescence and H-1 NMR spectroscopy. Journal of Molecular Biology 262 (1), pp. 53 - 68 (1996)

Klement, R.; Soumpasis, D. M.; Jovin, T. M.: Computation of ionic distributions around charged biomolecular structures: Results for right-handed and left-handed DNA. Proceedings of the National Academy of Sciences of the United States of America 88 (11), pp. 4631 - 4635 (1991)

Rippe, K.; Ramsing, N. B.; Klement, R.; Jovin, T. M.: A parallel stranded linear DNA duplex incorporating dG.dC base pairs. Journal of Biomolecular Structure & Dynamics 7 (6), pp. 1199 - 1209 (1990)

Klement, R.; Soumpasis, D. M.; von Kitzing, E.; Jovin, T. M.: Inclusion of ionic interactions in force field calculations of charged biomolecules – DNA structural transitions. Biopolymers 29 (6-7), pp. 1089 - 1103 (1990)

Klement, R.; Graen, T. M. D.; Grupi, A.; Haas, E.; Grubmüller, H.: Structural dynamics of monomeric alpha-synuclein on the ps-mu s time scale derived from MD simulations. 19th IUPAB Congress / 11th EBSA Congress, Edinburgh, Scotland, July 16, 2017 - July 20, 2017. European Biophysics Journal 46 (Suppl_1), p. S206 - S206 (2017)

Klement, R.; Graen, T.; Grupi , A.; Haas, E.; Grubmüller, H.: Molecular dynamics simulations of alpha-synuclein ensemble FRET measurements from different force fields. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, February 27, 2016 - March 02, 2016. Biophysical Journal 110 (Suppl 1), 3 Ed., p. 551A - 551A (2016)

Klement, R.; Grubmüller, H.: Local dynamics of FRET dyes in an intrinsically disordered protein studied by MD simulations. 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, February 15, 2014 - February 19, 2014. Biophysical Journal 106 (2, Suppl. 1), p. 609a - 609a (2014)