Publications of D. Görlich

Güttler, T.; Aksu, M.; Dickmanns, A.; Stegmann, K. M.; Gregor, K.; Rees, R.; Taxer, W.; Rymarenko, O.; Schünemann, J.; Dienemann, C. et al.; Gunkel, P.; Mussil, B.; Krull, J.; Teichmann, U.; Groß, U.; Cordes, V.; Dobbelstein, M.; Görlich, D.: Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies. EMBO Journal 40 (19), e107985 (2021)

Stegmann, K. M.; Dickmanns, A.; Gerber, S.; Nikolova, V.; Klemke, L.; Manzini, V.; Schlösser, D.; Bierwirth, C.; Freund, J.; Sitte, M. et al.; Lugert, R.; Salinas, G.; Meister, T. L.; Pfaender, S.; Görlich, D.; Wollnik, B.; Groß, U.; Dobbelstein, M.: The folate antagonist methotrexate diminishes replication of the coronavirus SARS-CoV-2 and enhances the antiviral efficacy of remdesivir in cell culture models. Virus Research 302, 198469 (2021)

Ng, S. C.; Güttler, T.; Görlich, D.: Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide. Nature Communications 12, 4047 (2021)

Frost, R.; Débarre, D.; Jana, S.; Bano, F.; Schünemann, J.; Görlich, D.; Richter, R. P.: A method to quantify molecular diffusion within thin solvated polymer films: A case study on films of natively unfolded nucleoporins. ACS Nano 14 (8), pp. 9938 - 9952 (2020)

Serres, M. P.; Samwer, M.; Truong Quang, B. A.; Lavoie, G.; Perera, U.; Görlich, D.; Charras, G.; Petronczki, M.; Roux, P. P.; Paluch, E. K.: F-actin interactome reveals vimentin as a key regulator of actin organization and cell mechanics in mitosis. Developmental Cell 52 (2), pp. 210 - 222 (2020)

Aksu, M.; Trakhanov, S.; Vera Rodriguez, A.; Görlich, D.: Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122. Journal of Cell Biology 218 (6), pp. 1839 - 1852 (2019)

Vera Rodriguez, A.; Frey, S.; Görlich, D.: Engineered SUMO/protease system identifies Pdr6 as a bidirectional nuclear transport receptor. The Journal of Cell Biology 218 (6), pp. 2006 - 2020 (2019)

Aksu, M.; Pleiner, T.; Karaca, S.; Kappert, C.; Dehne, H. J.; Seibel, K.; Urlaub, H.; Bohnsack, M. T.; Görlich, D.: Xpo7 is a broad-spectrum exportin and a nuclear import receptor. Journal of Cell Biology 217 (7), pp. 2329 - 2340 (2018)

Frey, S.; Rees, R.; Schünemann, J.; Ng, S. C.; Fünfgeld, K.; Huyton, T.; Görlich, D.: Surface properties determining passage rates of proteins through nuclear pores. Cell 174 (1), pp. 202 - 217 (2018)

Ananth, A.; Genua, M.; Aissaoui, N.; Diaz, L.; Eisele, N. B.; Frey, S.; Dekker, C.; Richter, R. P.; Görlich, D.: Reversible immobilization of proteins in sensors and solid-state nanopores. Small 14 (18), 1703357 (2018)

Pleiner, T.; Bates, M.; Görlich, D.: A toolbox of anti-mouse and anti-rabbit IgG secondary nanobodies. Journal of Cell Biology 217 (3), pp. 1143 - 1154 (2018)

Ananth, A. N.; Mishra, A.; Frey, S.; Dwarkasing, A.; Versloot, R.; van der Giessen, E.; Görlich, D.; Onck, P.; Dekker, C.: Spatial structure of disordered proteins dictates conductance and selectivity in Nuclear Pore Complex mimics. eLife 7, e31510 (2018)

Göttfert, F.; Pleiner, T.; Heine, J.; Westphal, V.; Görlich, D.; Sahl, S. J.; Hell, S. W.: Strong signal increase in STED fluorescence microscopy by imaging regions of subdiffraction extent. Proceedings of the National Academy of Sciences of the United States of America 114 (9), pp. 2125 - 2130 (2017)

Warda, A. S.; Freytag, B.; Haag, S.; Sloan, K. E.; Görlich, D.; Bohnsack, M.: Effects of the Bowen-Conradi syndrome mutation in EMG1 on its nuclear import, stability and nucleolar recruitment. Human Molecular Genetics 25 (24), pp. 5353 - 5364 (2016)

Aksu, M.; Trakhanov, S.; Görlich, D.: Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A. Nature Communications 7, 11952 (2016)

Zahn, R.; Osmanovic, D.; Ehret, S.; Callis, C. A.; Frey, S.; Stewart, M.; You, C. J.; Görlich, D.; Hoogenboom, B. W.; Richter, R. P.: A physical model describing the interaction of nuclear transport receptors with FG nucleoporin domain assemblies. eLife 5, e14119 (2016)

Schmidt, H. B.; Görlich, D.: Transport selectivity of nuclear pores, phase separation, and membraneless organelles. Trends in Biochemical Sciences 41 (1), pp. 46 - 61 (2016)

Kirli, K.; Karaca, S.; Dehne, H. J.; Samwer, M.; Pan, K. T.; Lenz, C.; Urlaub, H.; Görlich, D.: A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. eLife 4, e11466 (2015)

Pleiner, T.; Bates, M.; Trakhanov, S.; Lee, C. T.; Schliep, J. E.; Chug, H.; Böhning, M.; Stark, H.; Urlaub, H.; Görlich, D.: Nanobodies: Site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation. eLife 4, e11349 (2015)

Chug, H.; Trakhanov, S.; Hülsmann, B. B.; Pleiner, T.; Görlich, D.: Crystal structure of the metazoan Nup62•Nup58•Nup54 nucleoporin complex. Science 350 (6256), pp. 106 - 110 (2015)