Publications of Angel Perez-Lara

Pribicevic, S.; Graham, A. C.; Cafiso, D. S.; Perez-Lara, A.; Jahn, R.: Intermediate steps in the formation of neuronal SNARE complexes. Journal of Biological Chemistry 300 (8), 107591 (2024)

De Benito-Bueno, A.; Socuellamos, P. G.; Merinero, Y. G.; Cercos, P.; Izquierdo, C.; Daniel-Mozo, M.; Marin-Olivero, I.; Perez-Lara, A.; Gonzalez-Vera, J. A.; Orte, A. et al.; Albert, A.; Martin-Martinez, M.; Gutierrez-Rodriguez, M.; Valenzuela, C.: Modulation of K_V4.3-KChIP2 Channels by IQM-266: Role of DPP6 and KCNE2. International Journal of Molecular Sciences 23 (16), 9170 (2022)

Lakomek, N. A.; Yavuz, H.; Jahn, R.; Perez-Lara, A.: Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion. Proceedings of the National Academy of Sciences of the United States of America 116 (18), pp. 8699 - 8708 (2019)

Oroz, J.; Chang, B. J.; Wysoczanski, P.; Lee, C. T.; Perez-Lara, A.; Chakraborty, P.; Hofele, R. V.; Baker, J. D.; Blair, L. J.; Biernat, J. et al.; Urlaub, H.; Mandelkow, E.; Dickey, C. A.; Zweckstetter, M.: Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. Nature Communications 9, 4532 (2018)

Lüningschrör, P.; Binotti, B.; Dombert, B.; Heimann, P.; Perez-Lara, A.; Slotta, C.; Thau-Habermann, N.; von Collenberg, C. R.; Karl, F.; Damme, M. et al.; Horowitz, A.; Maystadt, I.; Füchtbauer, A.; Füchtbauer, E. M.; Jablonka, S.; Blum, R.; Üçeyler, N.; Petri, S.; Kaltschmidt, B.; Jahn, R.; Kaltschmidt, C.; Sendtner, M.: Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nature Communications 8, 678 (2017)

Scacioc, A.; Schmidt, C.; Hofmann, T.; Urlaub, H.; Kühnel, K.; Perez-Lara, A.: Structure based biophysical characterization of the PROPPIN Atg18 shows Atg18 oligomerization upon membrane binding. Scientific Reports 7, 14008 (2017)

Perez-Lara, A.; Thapa, A.; Nyenhuis, S. B.; Nyenhuis, D. A.; Halder, P.; Tietzel, M.; Tittmann, K.; Cafiso, D. S.; Jahn, R.: PtdInsP(2) and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium. eLife 5, e15886 (2016)

Park, Y.; Seo, J. B.; Fraind, A.; Perez-Lara, A.; Yavuz, H.; Han, K.; Jung, S. R.; Kattan, I.; Walla, P. J.; Choi, M. et al.; Cafiso, D. S.; Koh, D. S.; Jahn, R.: Synaptotagmin-1 binds to PIP2-containing membrane but not to SNAREs at physiological ionic strength. Nature Structural and Molecular Biology 22 (10), pp. 815 - 823 (2015)

Perez-Lara, A.; Jahn, R.: Extended synaptotagmins (E-Syts): Architecture and dynamics of membrane contact sites revealed. Proceedings of the National Academy of Sciences of the United States of America 112 (16), pp. 4837 - 4838 (2015)

Lin, C. C.; Seikowski, J.; Perez-Lara, A.; Jahn, R.; Höbartner, C.; Walla, P. J.: Control of membrane gaps by ​synaptotagmin-Ca2+ measured with a novel membrane distance ruler. Nature Communications 5, 5859 (2014)

Perez-Lara, A.; Thapa, A.; Nyenhuis, S.; Nyenhuis, D. A.; Halder, P.; Tietzel, M.; Tittmann, K.; Cafiso, D. S.; Jahn, R.: Kinetics of synaptotagmins-1 vesicle docking. Joint 12th EBSA European Biophysics Congress / 10th IUPAP International Conference on Biological Physics (ICBP), Madrid, Spain, July 20, 2019 - July 24, 2019. European Biophysics Journal 48 (Suppl 1), p. S124 - S124 (2019)

Oroz, J.; Chang, B. J.; Wysoczanski, P.; Lee, C. T.; Perez-Lara, A.; Chakraborty, P.; Hofele, R. V.; Baker, J. D.; Blair, L. J.; Biernat, J. et al.; Urlaub, H.; Mandelkow, E.; Dickey, C. A.; Zweckstetter, M.: Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. 71st Annual Meeting of the American-Academy-of-Neurology (AAN), Philadelphia, PA, May 04, 2019 - May 10, 2019. Neurology 92 (Suppl), P1.1-006, (2019)

Perez-Lara, A.; Thapa, A.; Nyenhuis, S. B.; Nyenhuis, D. A.; Halder, P.; Tietzel, M.; Tittmann, K.; Cafiso, D. S.; Jahn, R.: Cooperation of PtdInsP2 and PtdSer in synaptotagmin-1 membrane binding. 42nd Congress of the Federation of European Biochemical Societies (FEBS) on From Molecules to Cells and Back, Jerusalem, Israel, September 10, 2017 - September 14, 2017. FEBS Journal 284 (Suppl 1), p. 199 - 199 (2017)