Publications of P. Cramer

Niederberger, T.; Etzold, S.; Lidschreiber, M.; Maier, K. C.; Martin, D. E.; Fröhlich, H.; Cramer, P.; Tresch, A.: MC EMiNEM maps the interaction landscape of the Mediator. PLoS Computational Biology 8 (6), e1002568 (2012)

Treutlein, B.; Muschielok, A.; Andrecka, J.; Jawhari, A.; Buchen, C.; Kostrewa, D.; Hög, F.; Cramer, P.; Michaelis, J.: Dynamic architecture of a minimal RNA polymerase II open promoter complex. Molecular Cell 46 (2), pp. 136 - 146 (2012)

Walmacq, C.; Cheung, A. C. M.; Kireeva, M. L.; Lubkowska, L.; Ye, C.; Gotte, D.; Strathern, J. N.; Carell, T.; Cramer, P.; Kashlev, M.: Mechanism of translesion transcription by RNA polymerase II and its role in cellular resistance to DNA damage. Molecular Cell 46 (1), pp. 18 - 29 (2012)

Sun, M.; Schwalb, B.; Schulz, D.; Pirkl, N.; Etzold, S.; Larivière, L.; Maier, K. C.; Seizl, M.; Tresch, A.; Cramer, P.: Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation. Genome Research 22 (7), pp. 1350 - 1359 (2012)

Koschubs, T.; Dengl, S.; Dürr, H.; Kaluza, K.; Georges, G.; Hartl, C.; Jennewein, S.; Lanzendörfer, M.; Auer, J.; Stern, A. et al.; Huang, K.‑.; Packman, K.; Gubler, U.; Kostrewa, D.; Ries, S.; Hansen, S.; Kohnert, U.; Cramer, P.; Mundigl, O.: Allosteric antibody inhibition of human hepsin protease. Biochemical Journal 442 (3), pp. 483 - 494 (2012)

Jennebach, S.; Herzog, F.; Aebersold, R.; Cramer, P.: Crosslinking-MS analysis reveals RNA polymerase I domain architecture and basis of rRNA cleavage. Nucleic Acids Research 40 (12), pp. 5591 - 5601 (2012)

Wild, T.; Cramer, P.: Biogenesis of multisubunit RNA polymerases. Trends in Biochemical Sciences 37 (3), pp. 99 - 105 (2012)

Vannini, A.; Cramer, P.: Conservation between the RNA polymerase I, II, and III transcription initiation machineries. Molecular Cell 45 (4), pp. 439 - 446 (2012)

Larivière, L.; Seizl, M.; Cramer, P.: A structural perspective on Mediator function. Current Opinion in Cell Biology 24 (3), pp. 305 - 313 (2012)

Mayer, A.; Schreieck, A.; Lidschreiber, M.; Leike, K.; Martin, D. E.; Cramer, P.: The Spt5 C-terminal region recruits yeast 3= RNA cleavage factor I. Molecular and Cellular Biology 32 (7), pp. 1321 - 1331 (2012)

Schwalb, B.; Schulz, D.; Sun, M.; Zacher, B.; Dümcke, S.; Martin, D. E.; Cramer, P.; Tresch, A.: Measurement of genome-wide RNA synthesis and decay rates with Dynamic Transcriptome Analysis (DTA). Bioinformatics 28 (6), pp. 884 - 885 (2012)

Cheung, A. C. M.; Sainsbury, S.; Cramer, P.: Structural basis of initial RNA polymerase II transcription. EMBO Journal 30 (23), pp. 4755 - 4763 (2011)

Seizl, M.; Hartmann, H.; Hoeg, F.; Kurth, F.; Martin, D. E.; Söding, J.; Cramer, P.: A conserved GA element in TATA-less RNA polymerase II promoters. PLoS One 6 (11), e27595 (2011)

Ringel, R.; Sologub, M.; Morozov, Y. I.; Litonin, D.; Cramer, P.; Temiakov, D.: Structure of human mitochondrial RNA polymerase. Nature 478 (7368), pp. 269 - 273 (2011)

Blattner, C.; Jennebach, S.; Herzog, F.; Mayer, A.; Cheung, A. C. M.; Witte, G.; Lorenzen, K.; Hopfner, K.-P.; Heck, A. J. R.; Aebersold, R. et al.; Cramer, P.: Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth. Genes and Development 25 (19), pp. 2093 - 2105 (2011)

Geiger, S. R.; Böttcher, T.; Sieber, S. A.; Cramer, P.: A conformational switch underlies ClpP protease function. Angewandte Chemie International Edition 50 (25), pp. 5749 - 5752 (2011)

Czeko, E.; Seizl, M.; Augsberger, C.; Mielke, T.; Cramer, P.: Iwr1 directs RNA polymerase II nuclear import. Molecular cell 42 (2), pp. 261 - 266 (2011)

Müller, M.; Heym, R. G.; Mayer, A.; Kramer, K.; Schmid, M.; Cramer, P.; Urlaub, H.; Jansen, R. P.; Niessing, D.: A cytoplasmic complex mediates specific mRNA recognition and localization in yeast. PLoS Biology 9 (4), e1000611 (2011)

Seizl, M.; Larivière, L.; Pfaffeneder, T.; Wenzeck, L.; Cramer, P.: Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization. Nucleic Acids Research 39 (14), pp. 6291 - 6304 (2011)

Vojnic, E.; Mourão, A.; Seizl, M.; Simon, B.; Wenzeck, L.; Larivière, L.; Baumli, S.; Baumgart, K.; Meisterernst, M.; Sattler, M. et al.; Cramer, P.: Structure and VP16 binding of the Mediator Med25 activator interaction domain. Nature Structural and Molecular Biology 18 (4), pp. 404 - 409 (2011)