Publications of Mikael Simons

Cantuti-Castelvetri, L.; Fitzner, D.; Bosch-Queralt, M.; Weil, M.-T.; Su, M.; Sen, P.; Ruhwedel, T.; Mitkovski, M.; Trendelenburg, G.; Lütjohann, D. et al.; Möbius, W.; Simons, M.: Defective cholesterol clearance limits remyelination in the aged central nervous system. Science 359 (6376), pp. 684 - 688 (2018)

Fard, M. K.; van der Meer, F.; Sánchez, P.; Cantuti-Castelvetri, L.; Mandad, S.; Jäkel, S.; Fornasiero, E. F.; Schmitt, S.; Ehrlich, M.; Starost, L. et al.; Kuhlmann, T.; Sergiou, C.; Schultz, V.; Wrzos, C.; Brück, W.; Urlaub, H.; Dimou, L.; Stadelmann, C.; Simons, M.: BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions. Science translational medicine 9 (419), eaam7816 (2017)

Dimou, L.; Simons, M.: Diversity of oligodendrocytes and their progenitors. Current Opinion in Neurobiology 47, pp. 73 - 79 (2017)

Lüders, K. A.; Patzig, J.; Simons, M.; Nave, K.-A.; Werner, H. B.: Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2. Glia 65 (11), pp. 1762 - 1776 (2017)

Snaidero, N.; Velte, C.; Myllykoski, M.; Raasakka, A.; Ignatev, A.; Werner, H. B.; Erwig, M. S.; Möbius, W.; Kursula, P.; Nave, K.-A. et al.; Simons, M.: Antagonistic functions of MBP and CNP establish cytosolic channels in CNS myelin. Cell Reports 18, pp. 314 - 323 (2017)

Weil, M.-T.; Ruhwedel, T.; Möbius, W.; Simons, M.: Intracerebral injections and ultrastructural analysis of high-pressure frozen brain tissue. Current protocols in neuroscience 78, pp. 2.27.1 - 2.27.18 (2017)

Snaidero, N.; Simons, M.: The logistics of myelin biogenesis in the central nervous system. Glia 65 (7), pp. 1021 - 1031 (2017)

Romanelli, E.; Merkler, D.; Mezydlo, A.; Weil, M.-T.; Weber, M. S.; Niki´c, I.; Potz, S.; Meinl, E.; Matznick, F. E. H.; Kreutzfeldt, M. et al.; Ghanem, A.; Conzelmann, K.-K.; Metz, I.; Brück, W.; Routh, M.; Simons, M.; Bishop, D.; Misgeld, T.; Kerschensteiner, M.: Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model. Nature Communications 7, 13275 (2016)

Bunk, E. C.; Ertaylan, G.; Ortega, F.; Pavlou, M. A.; Gonzalez Cano, L.; Stergiopoulos, A.; Safaiyan, S.; Völs, S.; van Cann, M.; Politis, P. K. et al.; Simons, M.; Berninger, B.; Del Sol, A.; Schwamborn, J. C.: Prox1 is required for oligodendrocyte cell identity in adult neural stem cells of the subventricular zone. Stem Cells 34 (8), pp. 2115 - 2129 (2016)

Weil, M.-T.; Möbius, W.; Winkler, A.; Ruhwedel, T.; Wrzos, C.; Romanelli, E.; Bennett, J. L.; Enz, L.; Goebels, N.; Nave, K.-A. et al.; Kerschensteiner, M.; Schaeren-Wiemers, N.; Stadelmann, C.; Simons, M.: Loss of myelin basic protein function triggers myelin breakdown in models of demyelinating diseases. Cell Reports 16, pp. 314 - 322 (2016)

Steshenko, O.; Andrade, D. M.; Honigmann, A.; Mueller, V.; Schneider, F.; Sezgin, E.; Hell, S. W.; Simons, M.; Eggeling, C.: Reorganization of lipid diffusion by myelin basic protein as revealed by STED nanoscopy. Biophysical Journal 110 (11), pp. 2441 - 2450 (2016)

d'Este, E.; Kamin, D.; Velte, C.; Göttfert, F.; Simons, M.; Hell, S. W.: Subcortical cytoskeleton periodicity throughout the nervous system. Scientific Reports 6, 22741 (2016)

Baskin, J. M.; Wu, X.; Christiano, R.; Oh, M. S.; Schauder, C. M.; Gazzerro, E.; Messa, M.; Baldassari, S.; Assereto, S.; Biancheri, R. et al.; Zara, F.; Minetti, C.; Raimondi, A.; Simons, M.; Walther, T. C.; Reinisch, K. M.; Camilli, P. d.: The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane. Nature Cell Biology 18 (1), pp. 132 - 138 (2016)

Safaiyan, S.; Kannaiyan, N.; Snaidero, N.; Brioschi, S.; Biber, K.; Yona, S.; Edinger, A. L.; Jung, S.; Rossner, M. J.; Simons, M.: Age-related myelin degradation burdens the clearance function of microglia during aging. Nature Neuroscience 19, pp. 995 - 998 (2016)

Schneider, A.; Simons, M.: Catching filopodia: Exosomes surf on fast highways to enter cells. The Journal of Cell Biology: JCB 213 (2), pp. 143 - 145 (2016)

Simons, M.; Winckler, B.: Editorial overview: Cellular neuroscience. Current Opinion in Neurobiology 39, pp. V - VII (2016)

Schmitt, S.; Cantuti Castelvetri, L.; Simons, M.: Metabolism and functions of lipids in myelin. Biochimica et Biophysica Acta 1851 (8), pp. 999 - 1005 (2015)

Simons, M.; Nave, K.-A.: Oligodendrocytes: myelination and axonal support. Cold Spring Harbor Perspectives in Biology 8 (1), a020479 (2015)

Laulumaa, S.; Nieminen, T.; Lehtimäki, M.; Aggarwal, S.; Simons, M.; Koza, M. M.; Vattulainen, I.; Kursula, P.; Natali, F.: Dynamics of the peripheral membrane protein P2 from human myelin measured by neutron scattering - a comparison between wild-type protein and a hinge mutant. PLoS ONE 10 (6), e0128954 (2015)

de Hoz, L.; Simons, M.: The emerging functions of oligodendrocytes in regulating neuronal network behaviour. BioEssays 37 (1), pp. 60 - 69 (2015)