Publications of C. L. Will

Bessonov, S.; Anokhina, M.; Will, C. L.; Urlaub, H.; Luehrmann, R.: Isolation of an active step I spliceosome and composition of its RNP core. Nature 452 (7189), pp. 846 - 850 (2008)

Behzadnia, N.; Golas, M. M.; Hartmuth, K.; Sander, B.; Kastner, B.; Deckert, J.; Dube, P.; Will, C. L.; Urlaub, H.; Stark, H. et al.; Luehrmann, R.: Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. The EMBO Journal 26 (6), pp. 1737 - 1748 (2007)

Doenmez, G.; Hartmuth, K.; Kastner, B.; Will, C. L.; Luehrmann, R.: The 5′ end of U2 snRNA is in close proximity to U1 and functional sites of the Pre-mRNA in early spliceosomal complexes. Molecular Cell 25 (3), pp. 399 - 411 (2007)

Merz, C.; Urlaub, H.; Will, C. L.; Luehrmann, R.: Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment. RNA 13, pp. 116 - 128 (2007)

Deckert, J.; Hartmuth, K.; Boehringer, D.; Behzadnia, N.; Will, C. L.; Kastner, B.; Stark, H.; Urlaub, H.; Luehrmann, R.: Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Molecular and Cellular Biology 26 (14), pp. 5528 - 5543 (2006)

Dybkov, O.; Will, C. L.; Deckert, J.; Behzadnia, N.; Hartmuth, K.; Luehrmann, R.: U2 snRNA-protein contacts in purified human 17S U2 snRNPs and in spliceosomal A and B complexes. Molecular and Cellular Biology 26 (7), pp. 2803 - 2816 (2006)

Behzadnia, N.; Hartmuth, K.; Will, C. L.; Luehrmann, R.: Functional spliceosomal A complexes can be assembled in vitro in the absence of a penta-snRNP. RNA 12, pp. 1738 - 1746 (2006)

Benecke, H.; Luehrmann, R.; Will, C. L.: The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K protein. EMBO Journal 24 (17), pp. 3057 - 3069 (2005)

Will, C. L.; Luehrmann, R.: Splicing of a rare class of introns by the U12-dependent spliceosome. Biological Chemistry 386 (8), pp. 713 - 724 (2005)

Schneider, C.; Will, C. L.; Brosius, J.; Frilander, M. J.; Luehrmann, R.: Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila. Proceedings of the National Academy of Sciences of the United States of America 101 (26), pp. 9584 - 9589 (2004)

Makarova, O.; Makarov, E. M.; Urlaub, H.; Will, C. L.; Gentzel, M.; Wilm, M.; Luehrmann, R.: A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. EMBO Journal 23 (12), pp. 2381 - 2391 (2004)

Will, C. L.; Schneider, C.; Hossbach, M.; Urlaub, H.; Rauhut, R.; Elbashir, S. M.; Tuschl, T.; Luehrmann, R.: The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA 10 (6), pp. 929 - 941 (2004)

Pillai, R. S.; Grimmler, M.; Meister, G.; Will, C. L.; Luehrmann, R.; Fischer, U.; Schuemperli, D.: Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. Genes & Development 17 (18), pp. 2321 - 2333 (2003)

Golas, M. M.; Sander, B.; Will, C. L.; Luehrmann, R.; Stark, H.: Molecular architecture of the multiprotein splicing factor SF3b. Science 300, pp. 980 - 984 (2003)

Hartmuth, K.; Urlaub, H.; Vornlocher, H. P.; Will, C. L.; Gentzel, M.; Wilm, M.; Luehrmann, R.: Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Proceedings of the National Academy of Sciences of the United States of America 99 (26), pp. 16719 - 16724 (2002)

Makarov, E. M.; Makarova, O.; Urlaub, H.; Gentzel, M.; Will, C. L.; Wilm, M.; Luehrmann, R.: Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. Science 298 (5601), pp. 2205 - 2208 (2002)

Will, C. L.; Urlaub, H.; Achsel, T.; Gentzel, M.; Wilm, M.; Luehrmann, R.: Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. EMBO Journal 21 (18), pp. 4978 - 4988 (2002)

Schneider, C.; Will, C. L.; Makarova, O.; Makarov, E. M.; Luehrmann, R.: Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions. Molecular and Cellular Biology 22 (10), pp. 3219 - 3229 (2002)

Pillai, R. S.; Will, C. L.; Luehrmann, R.; Schuemperli, D.; Mueller, B.: Purified U7 snRNPs lack the Sm proteins D 1 and D 2 but contain Lsm 10, a new 14-kDa Sm D 1-like protein. EMBO Journal 20, pp. 5470 - 5479 (2001)

Will, C. L.; Luehrmann, R.: Spliceosomal U snRNP biogenesis, structure and function. Current Opinion in Cell Biology 13, pp. 290 - 301 (2001)