Publications of A. Chari
All genres
Journal Article (35)
1.
Journal Article
587 (7832), pp. 157 - 161 (2020)
Atomic-resolution protein structure determination by cryo-EM. Nature 2.
Journal Article
6 (30), eaba3916 (2020)
Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution. Science Advances 3.
Journal Article
180 (6), pp. 1130 - 1143.e20 (2020)
Discovery of a regulatory subunit of the yeast fatty acid synthase. Cell 4.
Journal Article
27 (7), pp. 1124 - 1136 (2019)
Structural and functional analyses of the human PDH complex suggest a "Division-of-Labor" mechanism by local E1 and E3 clusters. Structure 5.
Journal Article
17 (7), pp. 471 - 492 (2018)
Cryo-EM in drug discovery: Achievements, limitations and prospects. Nature Reviews Drug Discovery 6.
Journal Article
8, 15578 (2017)
Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nature Communications 7.
Journal Article
353 (6306), pp. 1399 - 1405 (2016)
Molecular architecture of the Saccharomyces cerevisiae activated spliceosome. Science 8.
Journal Article
16 (12), pp. 3103 - 3112 (2016)
The ribosome cooperates with the assembly chaperone pICln to initiate formation of snRNPs. Cell Reports 9.
Journal Article
353 (6299), pp. 594 - 598 (2016)
The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science 10.
Journal Article
65 (1), pp. 23 - 34 (2016)
Sample preparation of biological macromolecular assemblies for the determination of high-resolution structures by cryo-electron microscopy. Microscopy 11.
Journal Article
12 (9), pp. 859 - 865 (2015)
ProteoPlex: Stability optimization of macromolecular complexes by sparse-matrix screening of chemical space. Nature Methods 12.
Journal Article
34 (14), pp. 1925 - 1941 (2015)
Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organization. EMBO Journal 13.
Journal Article
21 (4), pp. 613 - 614 (2015)
Assembly of RNPs: help needed. RNA 14.
Journal Article
26 (2), pp. 161 - 171 (2015)
The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization. Molecular Biology of the Cell 15.
Journal Article
22 (6), pp. 923 - 930 (2014)
Translation initiation factor eIF3b contains a nine-bladed beta-propeller and interacts with the 40S ribosomal subunit. Structure 16.
Journal Article
93 (3), pp. 106 - 117 (2014)
Phosphoregulation of the human SMN complex. European Journal of Cell Biology 17.
Journal Article
49 (4), pp. 692 - 703 (2013)
Structural basis of assembly chaperone- mediated snRNP formation. Molecular Cell 18.
Journal Article
2 (5), pp. 718 - 731 (2011)
Biogenesis of spliceosomal small nuclear ribonucleoproteins. Wiley Interdisciplinary Reviews: RNA 19.
Journal Article
35 (12), pp. 676 - 683 (2010)
Cellular strategies for the assembly of molecular machines. Trends in biochemical sciences 20.
Journal Article
16 (8), pp. 1646 - 1659 (2010)
Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I. RNA