Max Planck Institute for Multidisciplinary Sciences

Publications

Journal Article (126)

1.

Journal Article

Marten, L.M.; Lüttgens, M.S.; Berečić, B.; Tiburcy, M.; Brüser, C.; Gupta, S.; Jakobs, S.; Ammer, E.; Ohlenbusch, A.; Krätzner, R. et al.; Rosewich, H.; Gärtner, J.: Mitochondrial dysfunction and impaired oxidative stress defense as potential trigger of cerebral X-linked adrenoleukodystrophy. Free Radical Biology and Medicine 242, pp. 654 - 666 (2026)

MPG.PuRe

2.

Journal Article

Habeck, M.; Saleem, H. N.; Plota, D.; Cheruiyot, C.; Kohl, T.; Lehnart, S. E.; Jakobs, S.; Ebert, A.: Sarcomere analysis in human cardiomyocytes by computing radial frequency spectra. Biological Chemistry (2025)

MPG.PuRe

3.

Journal Article

Last, M. G.F.; van Klaveren, M.; Janssen, L.; Jensen, N. A.; Jansen, I.; Jakobs, S.; Voortman, L. M.; Sharp, T. H.: Dual-colour super-resolution cryoCLEM in mammalian cells using the fluorescent proteins rsTagRFP and rsEGFP2. Journal of Structural Biology 217 (4), 108267 (2025)

MPG.PuRe

publisher-version

4.

Journal Article

Stumpf, D.; Jensen, N. A.; Mittelheisser, C.; Keller-Findeisen, J.; Chizhik, A. I.; Kamper, M.; Diekmann, T.; Habenstein, F.; Jansen, I.; Enderlein, J. et al.; Sliwa, M.; Inamdar, K.; Hell, S. W.; Jakobs, S.: The near-infrared bacteriophytochrome-derived fluorescent protein PENELOPE enables RESOLFT superresolution microscopy. Proceedings of the National Academy of Sciences of the United States of America 122 (48), e2504748122 (2025)

MPG.PuRe

publisher-version

5.

Journal Article

Reshetniak, S.; Bogaciu, C. A.; Bonn, S.; Brose, N.; Cooper, B. H.; D'Este, E.; Fauth, M.; Fernández‐Busnadiego, R.; Fiosins, M.; Fischer, A. et al.; Georgiev, S. V.; Jakobs, S.; Klumpp, S.; Köster, S.; Lange, F.; Lipstein, N.; Macarrón‐Palacios, V.; Milovanovic, D.; Moser, T.; Müller, M.; Opazo, F.; Outeiro, T. F.; Pape, C.; Priesemann, V.; Rehling, P.; Salditt, T.; Schlüter, O.; Simeth, N.; Steinem, C.; Tchumatchenko, T.; Tetzlaff, C.; Tirard, M.; Urlaub, H.; Wichmann, C.; Wolf, F.; Rizzoli, S. O.: The synaptic vesicle cluster as a controller of pre‐ and postsynaptic structure and function. The Journal of Physiology 603 (20), pp. 5935 - 5964 (2025)

MPG.PuRe

publisher-version

6.

Journal Article

Cruz-Zaragoza, L. D.; Dahal, D.; Koschel, M.; Boshnakovska, A.; Zheenbekova, A.; Yilmaz, M.; Morgenstern, M.; Dohrke, J.-N.; Bender, J.; Valpadashi, A. et al.; Henningfeld, K. A.; Oeljeklaus, S.; Kremer, L. S.; Breuer, M.; Urbach, O.; Dennerlein, S.; Lidschreiber, M.; Jakobs, S.; Warscheid, B.; Rehling, P.: Silencing mitochondrial gene expression in living cells. Science 389 (6759), 477 (2025)

MPG.PuRe

7.

Journal Article

Stoldt, S.; Maass, F.; Weber, M.; Dennerlein, S.; Ilgen, P.; Gärtner, J.; Canfes, A.; Schweighofer, S. V.; Jans, D. C.; Rehling, P. et al.; Jakobs, S.: Super-resolution microscopy of mitochondrial mRNAs. Nature Communications 16, 6391 (2025)

MPG.PuRe

publisher-version

8.

Journal Article

Preminger, N.; Zucker, B.; Hassdenteufel, S.; Stephan, T.; Jakobs, S.; Kozlov, M. M.; Schuldiner, M.: A data-driven model for mitochondrial inner membrane remodeling as a driving force of organelle shaping. Journal of Cell Science 138 (12), jcs263850 (2025)

MPG.PuRe

publisher-version

9.

Journal Article

Lange, F.; Ratz, M.; Dohrke, J.-N.; Le Vasseur, M.; Wenzel, D.; Ilgen, P.; Riedel, D.; Jakobs, S.: In situ architecture of the human prohibitin complex. Nature Cell Biology 27, pp. 633 - 640 (2025)

MPG.PuRe

publisher-version

10.

Journal Article

Saller, B. S.; Wöhrle, S.; Fischer, L.; Dufossez, C.; Ingerl, I. L.; Kessler, S.; Mateo-Tortola, M.; Gorka, O.; Lange, F.; Cheng, Y. et al.; Neuwirt, E.; Marada, A.; Koentges, C.; Urban, C.; Aktories, P.; Reuther, P.; Giese, S.; Kirschnek, S.; Mayer, C.; Pilic, J.; Falquez-Medina, H.; Oelgeklaus, A.; Deepagan, V. G.; Shojaee, F.; Zimmermann, J. A.; Weber, D.; Tai, Y.-H.; Crois, A.; Ciminski, K.; Peyronnet, R.; Brandenburg, K. S.; Wu, G.; Baumeister, R.; Heimbucher, T.; Rizzi, M.; Riedel, D.; Helmstädter, M.; Buescher, J.; Neumann, K.; Misgeld, T.; Kerschensteiner, M.; Walentek, P.; Kreutz, C.; Maurer, U.; Rambold, A. S.; Vince, J. E.; Edlich, F.; Malli, R.; Häcker, G.; Kierdorf, K.; Meisinger, C.; Köttgen, A.; Jakobs, S.; Weber, A. N.R.; Schwemmle, M.; Groß, C. J.; Groß, O.: Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation. Immunity 58 (1), pp. 90 - 107.e11 (2025)

MPG.PuRe

publisher-version

11.

Journal Article

Elancheliyan, P.; Maruszczak, K. K.; Serwa, R. A.; Stephan, T.; Gulgec, A. S.; Borrero-Landazabal, M. A.; Ngati, S.; Gosk, A.; Jakobs, S.; Wasilewski, M. et al.; Chacinska, A.: OCIAD1 and prohibitins regulate the stability of the TIM23 protein translocase. Cell Reports 43 (12), 115038 (2024)

MPG.PuRe

publisher-version

12.

Journal Article

Scholz, J.; Stephan, T.; Pérez, A. G.; Csiszár, A.; Hersch, N.; Fischer, L. S.; Brühmann, S.; Körber, S.; Litschko, C.; Mijanovic, L. et al.; Kaufmann, T.; Lange, F.; Springer, R.; Pich, A.; Jakobs, S.; Peckham, M.; Tarantola, M.; Grashoff, C.; Merkel, R.; Faix, J.: Decisive role of mDia-family formins in cell cortex function of highly adherent cells. Science Advances 10 (44), eadp5929 (2024)

MPG.PuRe

publisher-version

13.

Journal Article

Sahl, S. J.; Matthias, J.; Inamdar, K.; Weber, M.; Khan, T. A.; Brüser, C.; Jakobs, S.; Becker, S.; Griesinger, C.; Broichhagen, J. et al.; Hell, S. W.: Direct optical measurement of intramolecular distances with angstrom precision. Science 386 (6718), pp. 180 - 187 (2024)

MPG.PuRe

14.

Journal Article

Naas, J.; Nies, G.; Li, H.; Stoldt, S.; Schmitzer, B.; Jakobs, S.; Munk, A.: MultiMatch: geometry-informed colocalization in multi-color super-resolution microscopy. Communications Biology 7, 1139 (2024)

MPG.PuRe

publisher-version

15.

Journal Article

Stephan, T.; Ilgen, P.; Jakobs, S.: Visualizing mitochondrial dynamics at the nanoscale. Light: Science & Applications 13, 244 (2024)

MPG.PuRe

publisher-version

16.

Journal Article

Aich, A.; Boshnakovska, A.; Witte, S.; Gall, T.; Unthan-Fechner, K.; Yousefi, R.; Chowdhury, A.; Dahal, D.; Methi, A.; Kaufmann, S. et al.; Silbern, I.; Prochazka, J.; Nichtova, Z.; Palkova, M.; Raishbrook, M.; Koubkova, G.; Sedlacek, R.; Tröder, S.E.; Zevnik, B.; Riedel, D.; Michanski, S.; Möbius, W.; Ströbel, P.; Lüchtenborg, C.; Giavalisco, P.; Urlaub, H.; Fischer, A.; Brügger, B.; Jakobs, S.; Rehling, P.: Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver. Nature Communications 15, 6914 (2024)

MPG.PuRe

publisher-version

17.

Journal Article

Saleem, H. N.; Ignatyeva, N.; Stuut, C.; Jakobs, S.; Habeck, M.; Ebert, A.: 3D Computational Modeling of Defective Early Endosome Distribution in Human iPSC-Based Cardiomyopathy Models. Cells 13 (11), p. 923 (2024)

MPG.PuRe

publisher-version

18.

Journal Article

Schweighofer, S. V.; Jans, D. C.; Keller-Findeisen, J.; Folmeg, A.; Ilgen, P.; Bates, M.; Jakobs, S.: Endogenous BAX and BAK form mosaic rings of variable size and composition on apoptotic mitochondria. Cell Death & Differentiation 31, pp. 469 - 478 (2024)

MPG.PuRe

publisher-version

19.

Journal Article

Hintze, A.; Lange, F.; Steyer, A. M.; Anstatt, J.; Möbius, W.; Jakobs, S.; Wichmann, C.: Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus. iScience 27 (1), 108700 (2024)

MPG.PuRe

publisher-version

20.

Journal Article

Stephan, T.; Stoldt, S.; Barbot, M.; Carney, T. D.; Lange, F.; Bates, M.; Bou Dib, P.; Inamdar, K.; Shcherbata, H. R.; Meinecke, M. et al.; Riedel, D.; Dennerlein, S.; Rehling, P.; Jakobs, S.: Drosophila MIC10b can polymerize into cristae-shaping filaments. Life science alliance 7 (4), e202302177 (2024)

MPG.PuRe

publisher-version

21.

Journal Article

Kim, D.; Stoldt, S.; Weber, M.; Jakobs, S.; Belov, V. N.; Hell, S. W.: A Bright Surprise: Live-Cell Labeling with Negatively Charged Fluorescent Probes based on Disulfonated Rhodamines and HaloTag. Chemistry Methods 3 (9), e202200076 (2023)

MPG.PuRe

publisher-version

22.

Journal Article

Stejerean-Todoran, I.; Zimmermann, K.; Gibhardt, C. S.; Vultur, A.; Ickes, C.; Shannan, B.; Rio, Z. B. d.; Wölling, A.; Cappello, S.; Sung, H.-M. et al.; Shumanska, M.; Zhang, X.; Nanadikar, M.; Latif, M. U.; Wittek, A.; Lange, F.; Waters, A.; Brafford, P.; Wilting, J.; Urlaub, H.; Katschinski, D. M.; Rehling, P.; Lenz, C.; Jakobs, S.; Ellenrieder, V.; Roesch, A.; Schön, M. P.; Herlyn, M.; Stanisz, H.; Bogeski, I.: MCU controls melanoma progression through a redox-controlled phenotype switch. EMBO Reports 23, e54746 (2022)

MPG.PuRe

publisher-version

23.

Journal Article

Ostersehlt, L.-M.; Jans, D. C.; Wittek, A.; Keller-Findeisen, J.; Inamdar, K.; Sahl, S.; Hell, S. W.; Jakobs, S.: DNA-PAINT MINFLUX nanoscopy. Nature Methods 19, pp. 1072 - 1075 (2022)

MPG.PuRe

publisher-version

24.

Journal Article

Bock-Bierbaum, T.; Funck, K.; Wollweber, F.; Lisicki, E.; von der Malsburg, K.; von der Malsburg, A.; Laborenz, J.; Noel, J. K.; Hessenberger, M.; Jungbluth, S. et al.; Bernert, C.; Kunz, S.; Riedel, D.; Lilie, H.; Jakobs, S.; van der Laan, M.; Daumke, O.: Structural insights into crista junction formation by the Mic60-Mic19 complex. Science Advances 8 (35), eabo4946 (2022)

MPG.PuRe

publisher-version

25.

Journal Article

Bates, M.; Keller-Findeisen, J.; Przybylski, A.; Hüper, A.; Stephan, T.; Ilgen, P.; Cereceda Delgado, A.R.; D’Este, E.; Egner, A.; Jakobs, S. et al.; Sahl, S. J.; Hell, S. W.: Optimal precision and accuracy in 4Pi-STORM using dynamic spline PSF models. Nature Methods 19 (5), pp. 603 - 612 (2022)

MPG.PuRe

publisher-version

26.

Journal Article

Dennerlein, S.; Poerschke, S.; Oeljeklaus, S.; Wang, C.; Richter-Dennerlein, R.; Sattmann, J.; Bauermeister, D.; Hanitsch, E.; Stoldt, S.; Langer, T. et al.; Jakobs, S.; Warscheid, B.; Rehling, P.: Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors. eLife 10, e68213 (2021)

MPG.PuRe

publisher-version

27.

Journal Article

Brüser, C.; Keller-Findeisen, J.; Jakobs, S.: The TFAM-to-mtDNA ratio defines inner-cellular nucleoid populations with distinct activity levels. Cell Reports 37 (8), 110000 (2021)

MPG.PuRe

publisher-version

28.

Journal Article

Gomkale, R.; Linden, A.; Neumann, P.; Schendzielorz, A. B.; Stoldt, S.; Dybkov, O.; Kilisch, M.; Schulz, C.; Cruz-Zaragoza, L. D.; Schwappach, B. et al.; Ficner, R.; Jakobs, S.; Urlaub, H.; Rehling, P.: Mapping protein interactions in the active TOM-TIM23 supercomplex. Nature Communications 12, 5715 (2021)

MPG.PuRe

publisher-version

29.

Journal Article

Bollmann, F.; Dohrke, J.-N.; Wurm, C. A.; Jans, D. C.; Jakobs, S.: Mitochondrial protein abundance gradients require the distribution of separated mitochondria. Biology 10 (7), 572 (2021)

MPG.PuRe

publisher-version

30.

Journal Article

Konen, T.; Stumpf, D.; Grotjohann, T.; Jansen, I.; Bossi, M.; Weber, M.; Jensen, N. A.; Hell, S. W.; Jakobs, S.: The positive switching fluorescent protein Padron2 enables live-cell reversible saturable optical linear fluorescence transitions (RESOLFT) nanoscopy without sequential illumination steps. ACS Nano 15 (6), pp. 9509 - 9521 (2021)

MPG.PuRe

31.

Journal Article

Yousefi, R.; Fornasiero, E. F.; Cyganek, L.; Montoya, J.; Jakobs, S.; Rizzoli, S. O.; Rehling, P.; Pacheu-Grau, D.: Monitoring mitochondrial translation in living cells. EMBO Reports 22 (4), e51635 (2021)

MPG.PuRe

publisher-version

32.

Journal Article

Weber, M.; Leutenegger, M.; Stoldt, S.; Jakobs, S.; Mihaila, T. S.; Butkevich, A. N.; Hell, S. W.: MINSTED fluorescence localization and nanoscopy. Nature Photonics 15, pp. 361 - 366 (2021)

MPG.PuRe

publisher-version

33.

Journal Article

Stephan, T.; Ilgen, P.; Jakobs, S.: Innenarchitektur der Zellkraftwerke: Membranfalten in Hochauflösung. BIOspektrum 27 (2), pp. 161 - 164 (2021)

MPG.PuRe

publisher-version

34.

Journal Article

Ruhlandt, D.; Andresen, M.; Jensen, N. A.; Gregor, I.; Jakobs, S.; Enderlein, J.; Chizhik, A. I.: Absolute quantum yield measurements of fluorescent proteins using a plasmonic nanocavity. Communications Biology 3, 627 (2020)

MPG.PuRe

publisher-version

35.

Journal Article

Lange, F.; Agüi-Gonzalez, P.; Riedel, D.; Phan, N. T. N.; Jakobs, S.; Rizzoli, S. O.: Correlative fluorescence microscopy, transmission electron microscopy and secondary ion mass spectrometry (CLEM-SIMS) for cellular imaging. bioRxiv, 10.1101/2020.10.05.326074 (2020)

MPG.PuRe

36.

Journal Article

Pape, J. K.; Stephan, T.; Balzarotti, F.; Büchner, R.; Lange, F.; Riedel, D.; Jakobs, S.; Hell, S. W.: Multicolor 3D MINFLUX nanoscopy of mitochondrial MICOS proteins. Proceedings of the National Academy of Sciences of the USA 117 (34), pp. 20607 - 20614 (2020)

MPG.PuRe

publisher-version

supplementary-material

37.

Journal Article

Stephan, T.; Brüser, C.; Deckers, M.; Steyer, A. M.; Balzarotti, F.; Barbot, M.; Behr, T. S.; Heim, G.; Hübner, W.; Ilgen, P. et al.; Lange, F.; Pacheu‐Grau, D.; Pape, J. K.; Stoldt, S.; Huser, T.; Hell, S. W.; Möbius, W.; Rehling, P.; Riedel, D.; Jakobs, S.: MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation. EMBO Journal 39 (14), e104105 (2020)

MPG.PuRe

publisher-version

38.

Journal Article

Jakobs, S.; Stephan, T.; Ilgen, P.; Brueser, C.: Light microscopy of mitochondria at the nanoscale. Annual Review of Biophysics 49, (in press) (2020)

MPG.PuRe

39.

Journal Article

Woodhouse, J.; Nass Kovacs, G.; Coquelle, N.; Uriarte, L. M.; Adam, V.; Barends, T. R. M.; Byrdin, M.; de la Mora, E.; Bruce Doak, R.; Feliks, M. et al.; Field, M.; Fieschi, F.; Guillon, V.; Jakobs, S.; Joti, Y.; Macheboeuf, P.; Motomura, K.; Nass, K.; Owada, S.; Roome, C. M.; Ruckebusch, C.; Schirò, G.; Shoeman, R. L.; Thepaut, M.; Togashi, T.; Tono, K.; Yabashi, M.; Cammarata, M.; Foucar, L.; Bourgeois, D.; Sliwa, M.; Colletier, J. P.; Schlichting, I.; Weik, M.: Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy. Nature Communications 11 (1), 741 (2020)

MPG.PuRe

publisher-version

supplementary-material

40.

Journal Article

Toth, A.; Meyrat, A.; Stoldt, S.; Santiago, R.; Wenzel, D.; Jakobs, S.; von Ballmoos, C.; Ott, M.: Kinetic coupling of the respiratory chain with ATP synthase, but not proton gradients, drives ATP production in cristae membranes. Proceedings of the National Academy of Sciences of the United States of America 117 (5), pp. 2412 - 2421 (2020)

MPG.PuRe

publisher-version

supplementary-material

41.

Journal Article

Wurm, C. A.; Schwarz, H.; Jans, D. C.; Riedel, D.; Humbel, B. M.; Jakobs, S.: Correlative STED super-resolution light and electron microscopy on resin sections. Journal of Physics D: Applied Physics 52 (37), 374003 (2019)

MPG.PuRe

42.

Journal Article

Frahm, L.; Keller, J.; Alt, P.; Schnorrenberg, S.; Ruiz, M. D.; Aspelmeier, T.; Munk, A.; Jakobs, S.; Hell, S. W.: Molecular contribution function in RESOLFT nanoscopy. Optics Express 27 (15), pp. 21956 - 21987 (2019)

MPG.PuRe

publisher-version

43.

Journal Article

Callegari, S.; Müller, T.; Schulz, C.; Lenz, C.; Jans, D. C.; Wissel, M.; Opazo, F.; Rizzoli, S. O.; Jakobs, S.; Urlaub, H. et al.; Rehling, P.; Deckers, M.: A MICOS-TIM22 association promotes carrier import into human mitochondria. Journal of Molecular Biology 431 (15), pp. 2835 - 2851 (2019)

MPG.PuRe

publisher-version

44.

Journal Article

Ramos, E. S.; Motori, E.; Brüser, C.; Kühl, I.; Yeroslaviz, A.; Ruzzenente, B.; Kauppila, J. H. K.; Busch, J. D.; Hultenby, K.; Habermann, B. H. et al.; Jakobs, S.; Larsson, N. G.; Mourier, A.: Mitochondrial fusion is required for regulation of mitochondrial DNA replication. PLoS Genetics 15 (6), e1008085 (2019)

MPG.PuRe

publisher-version

45.

Journal Article

Stoldt, S.; Stephan, T.; Jans, D. C.; Brüser, C.; Lange, F.; Keller-Findeisen, J.; Riedel, D.; Hell, S. W.; Jakobs, S.: Mic60 exhibits a coordinated clustered distribution along and across yeast and mammalian mitochondria. Proceedings of the National Academy of Sciences of the United States of America 116 (20), pp. 9853 - 9858 (2019)

MPG.PuRe

publisher-version

supplementary-material

46.

Journal Article

Richter, F.; Dennerlein, S.; Nikolov, M.; Jans, D. C.; Naumenko, N.; Aich, A.; MacVicar, T.; Linden, A.; Jakobs, S.; Urlaub, H. et al.; Langer, T.; Rehling, P.: ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. The Journal of Cell Biology 218 (2), 598 (2019)

MPG.PuRe

publisher-version

47.

Journal Article

Tuijtel, M. W.; Koster, A. J.; Jakobs, S.; Faas, F. G. A.; Sharp, T. H.: Correlative cryo super-resolution light and electron microscopy on mammalian cells using fluorescent proteins. Scientific Reportsvolume 9 (1), 1369 (2019)

MPG.PuRe

publisher-version

supplementary-material

48.

Journal Article

Stephan, T.; Roesch, A.; Riedel, D.; Jakobs, S.: Live-cell STED nanoscopy of mitochondrial cristae. Scientific Reports 9 (1), 12419 (2019)

MPG.PuRe

publisher-version

supplementary-material

49.

Journal Article

Kamper, M.; Ta, H.; Jensen, N. A.; Hell, S. W.; Jakobs, S.: Near-infrared STED nanoscopy with an engineered bacterial phytochrome. Nature Communications 9, 4762 (2018)

MPG.PuRe

publisher-version

50.

Journal Article

Roubinet, B.; Bischoff, M.; Nizamov, S.; Yan, S.; Geisler, C.; Stoldt, S.; Mitronova, G.; Belov, V. N.; Bossi, M. L.; Hell, S. W.: Photoactivatable rhodamine spiroamides and diazoketones decorated with “universal hydrophilizer” or hydroxyl groups. The Journal of Organic Chemistry 83 (12), pp. 6466 - 6476 (2018)

MPG.PuRe

supplementary-material

51.

Journal Article

Stoldt, S.; Wenzel, D.; Kehrein, K.; Riedel, D.; Ott, M.; Jakobs, S.: Spatial orchestration of mitochondrial translation and OXPHOS complex assembly. Nature Cell Biology 20 (5), pp. 528 - 534 (2018)

MPG.PuRe

supplementary-material

supplementary-material

52.

Journal Article

Butkevich, A.; Ta, H.; Ratz, M.; Stoldt, S.; Jakobs, S.; Belov, V. N.; Hell, S. W.: Two-color 810 nm STED nanoscopy of living cells with endogenous SNAP-tagged fusion proteins. ACS Chemical Biology 13 (2), pp. 475 - 480 (2018)

MPG.PuRe

supplementary-material

53.

Journal Article

Faoro, R.; Bassu, M.; Mejia, Y. X.; Stephan, T.; Dudani, N.; Boeker, C.; Jakobs, S.; Burg, T. P.: Aberration-corrected cryoimmersion light microscopy. Proceedings of the National Academy of Sciences of the United States of America 115 (6), pp. 1204 - 1209 (2018)

MPG.PuRe

publisher-version

54.

Journal Article

Coquelle, N.; Sliwa, M.; Woodhouse, J.; Schirò, G.; Adam, V.; Aquila, A.; Barends, T. R. M.; Boutet, S.; Byrdin, M.; Carbajo, S. et al.; De a Mora, E.; Doak, R. B.; Feliks, M.; Fieschi, F.; Foucar, L.; Guillon, V.; Hilpert, M.; Hunter, M. S.; Jakobs, S.; Koglin, J. E.; Kovacsova, G.; Lane, T. J.; Lévy, B.; Liang, M.; Nass, K.; Ridard, J.; Robinson, J. S.; Roome, C. M.; Ruckebusch, C.; Seaberg, M.; Thepaut, M.; Cammarata, M.; Demachy, I.; Field, M.; Shoeman, R. L.; Bourgeois, D.; Colletier, J. P.; Schlichting, I.; Weik, M.: Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography. Nature Chemistry 10 (1), pp. 31 - 37 (2018)

MPG.PuRe

supplementary-material

55.

Journal Article

Sahl, S. J.; Hell, S. W.; Jakobs, S.: Fluorescence nanoscopy in cell biology. Nature Reviews Molecular Cell Biology 18 (11), pp. 685 - 701 (2017)

MPG.PuRe

supplementary-material

56.

Journal Article

Tarasenko, D.; Barbot, M.; Jans, D. C.; Kroppen, B.; Sadowski, B.; Heim, G.; Möbius, W.; Jakobs, S.; Meinecke, M.: The MICOS component Mic60 displays a conserved membrane-bending activity that is necessary for normal cristae morphology. Journal of Cell Biology 216 (4), pp. 889 - 899 (2017)

MPG.PuRe

publisher-version

57.

Journal Article

Chmyrov, A.; Leutenegger, M.; Grotjohann, T.; Schönle, A.; Keller-Findeisen, J.; Kastrup, L.; Jakobs, S.; Donnert, G.; Sahl, S. J.; Hell, S. W.: Achromatic light patterning and improved image reconstruction for parallelized RESOLFT nanoscopy. Scientific Reports 7, 44619 (2017)

MPG.PuRe

publisher-version

supplementary-material

58.

Journal Article

Callegari, S.; Richter, F.; Chojnacka, K.; Jans, D. C.; Lorenzi, I.; Pacheu-Grau, D.; Jakobs, S.; Lenz, C.; Urlaub, H.; Dudek, J. et al.; Chacinska, A.; Rehling, P.: TIM29 is a subunit of the human carrier translocase required for protein transport. FEBS Letters 590 (23), pp. 4147 - 4158 (2016)

MPG.PuRe

publisher-version

59.

Journal Article

Schnorrenberg, S.; Grotjohann, T.; Vorbrüggen, G.; Herzig, A.; Hell, S. W.; Jakobs, S.: In vivo super-resolution RESOLFT microscopy of Drosophila melanogaster. eLife 5, e15567 (2016)

MPG.PuRe

publisher-version

supplementary-material

60.

Journal Article

Sahl, S. J.; Balzarotti, F.; Keller-Findeisen, J.; Leutenegger, M.; Westphal, V.; Egner, A.; Lavoie-Cardinal, F.; Chmyrov, A.; Grotjohann, T.; Jakobs, S.: Comment on "Extended-resolution structured illumination imaging of endocytic and cytoskeletal dynamics". Science 352 (6285), 527a (2016)

MPG.PuRe

61.

Journal Article

Große, L.; Wurm, C. A.; Brüser, C.; Neumann, D.; Jans, D. C.; Jakobs, S.: Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis. EMBO Journal 35 (4), pp. 402 - 413 (2016)

MPG.PuRe

publisher-version

supplementary-material

supplementary-material

62.

Journal Article

Danzl, J. G.; Sidenstein, S.; Gregor, C.; Urban, N. T.; Ilgen, P.; Jakobs, S.; Hell, S. W.: Coordinate-targeted fluorescence nanoscopy with multiple off states. Nature Photonics 10 (2), pp. 122 - 128 (2016)

MPG.PuRe

supplementary-material

63.

Journal Article

Sakowska, P.; Jans, D. C.; Mohanraj, K.; Riedel, D.; Jakobs, S.; Chacinska, A.: The oxidation status of Mic19 regulates MICOS assembly. Molecular and Cellular Biology 35 (24), pp. 4222 - 4237 (2015)

MPG.PuRe

publisher-version

64.

Journal Article

Hell, S. W.; Sahl, S. J.; Bates, M.; Zhuang, X.; Heintzmann, R.; Booth, M. J.; Bewersdorf, J.; Shtengel, G.; Hess, H.; Tinnefeld, P. et al.; Honigmann, A.; Jakobs, S.; Testa, I.; Cognet, L.; Lounis, B.; Ewers, H.; Davis, S. J.; Eggeling, C.; Klenerman, D.; Willig, K. I.; Vicidomini, G.; Castello, M.; Diaspro, A.; Cordes, T.: The 2015 super-resolution microscopy roadmap. Journal of Physics D: Applied Physics 48 (44), 443001 (2015)

MPG.PuRe

publisher-version

65.

Journal Article

Ilgen, P.; Grotjohann, T.; Jans, D. C.; Kilisch, M.; Hell, S. W.; Jakobs, S.: RESOLFT nanoscopy of fixed cells using a Z-domain based fusion protein for labelling. PLoS One 10 (9), e0136233 (2015)

MPG.PuRe

publisher-version

supplementary-material

supplementary-material

66.

Journal Article

Dennerlein, S.; Oeljeklaus, S.; Jans, D. C.; Hellwig, C.; Bareth, B.; Jakobs, S.; Deckers, M.; Warscheid, B.; Rehling, P.: MITRAC7 defines a checkpoint during cytochrome c oxidase assembly. Cell Reports 12 (10), pp. 1644 - 1655 (2015)

MPG.PuRe

publisher-version

supplementary-material

supplementary-material

67.

Journal Article

Kukat, C.; Davies, M. K.; Wurm, C. A.; Spåhr, H.; Bonekamp, A.; Kühl, I.; Joos, F.; Loguercio-Polosa, P.; Park, B.; Poss, V. et al.; Falkenberg, M.; Jakobs, S.; Kühlbrandt, W.; Larsson, N. G.: Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid. Proceedings of the National Academy of Sciences of the United States of America 112 (36), pp. 11288 - 11293 (2015)

MPG.PuRe

publisher-version

supplementary-material

68.

Journal Article

Barbot, M.; Jans, D. C.; Schulz, C.; Denkert, N.; Kroppen, B.; Hoppert, M.; Jakobs, S.; Meinecke, M.: Mic10 oligomerizes to bend mitochondrial inner membranes at cristae junctions. Cell Metabolism 21 (5), pp. 756 - 763 (2015)

MPG.PuRe

supplementary-material

supplementary-material

69.

Journal Article

Walter, A.; Andresen, M.; Jakobs, S.; Schroeder, J.; Schwarzer, D.: Primary light-induced reaction steps of reversibly photoswitchable fluorescent protein padron0.9 investigated by femtosecond spectroscopy. Journal of Physical Chemistry B 119 (16), pp. 5136 - 5144 (2015)

MPG.PuRe

supplementary-material

70.

Journal Article

Ratz, M.; Testa, I.; Hell, S. W.; Jakobs, S.: CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells. Scientific Reports 5, 9592 (2015)

MPG.PuRe

publisher-version

supplementary-material

71.

Journal Article

Kehrein, K.; Schilling, R.; Möller-Hergt, B. V.; Wurm, C. A.; Jakobs, S.; Lamkemeyer, T.; Langer, T.; Ott, M.: Organization of mitochondrial gene expression in two distinct ribosome-containing assemblies. Cell Reports 10 (6), pp. 843 - 853 (2015)

MPG.PuRe

publisher-version

supplementary-material

supplementary-material

72.

Journal Article

Duwe, S.; De Zitter, E.; Gielen, V.; Moeyaert, B.; Vandenberg, W.; Grotjohann, T.; Clays, K.; Jakobs, S.; Van Meervelt, L.; Dedecker, P.: Expression-enhanced fluorescent proteins based on enhanced green fluorescent protein for super-resolution microscopy. ACS Nano 9 (10), pp. 9528 - 9541 (2015)

MPG.PuRe

supplementary-material

73.

Journal Article

Geissbuehler, S.; Sharipov, A.; Godinat, A.; Bocchio, N. L.; Sandoz, P. A.; Huss, A.; Jensen, N. A.; Jakobs, S.; Enderlein, J.; van der Goot, F. G. et al.; Dubikovskaya, E. A.; Lasser, T.; Leutenegger, M.: Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging. Nature Communications 5, 5830 (2014)

MPG.PuRe

publisher-version

supplementary-material

74.

Journal Article

Ilgen, P.; Stoldt, S.; Conradi, L. C.; Wurm, C. A.; Rüschoff, J.; Ghadimi, B. M.; Liersch, T.; Jakobs, S.: STED super-resolution microscopy of clinical paraffin-embedded human rectal cancer tissue. PLoS One 9 (7), e101563 (2014)

MPG.PuRe

publisher-version

75.

Journal Article

Jakobs, S.; Wurm, C. A.: Super-resolution microscopy of mitochondria. Current Opinion in Chemical Biology 20, pp. 9 - 15 (2014)

MPG.PuRe

publisher-version

76.

Journal Article

Pfanner, N.; van der Laan, M.; Amati, P.; Capaldi, R. A.; Caudy, A. A.; Chacinska, A.; Darshi, M.; Deckers, M.; Hoppins, S.; Icho, T. et al.; Jakobs, S.; Ji, J.; Kozjak-Pavlovic, V.; Meisinger, C.; Odgren, P. R.; Park, S. K.; Rehling, P.; Reichert, A. S.; Sheikh, M. S.; Taylor, S. S.; Tsuchida, N.; van der Bliek, A. M.; van der Klei, I. J.; Weissman, J. S.; Westermann, B.; Zha, J. P.; Neupert, W.; Nunnari, J.: Uniform nomenclature for the mitochondrial contact site and cristae organizing system. Journal of Cell Biology 204 (7), pp. 1083 - 1086 (2014)

MPG.PuRe

publisher-version

77.

Journal Article

Jensen, N. A.; Danzl, J. G.; Willig, K. I.; Lavoie-Cardinal, F.; Brakemann, T.; Hell, S. W.; Jakobs, S.: Coordinate-targeted and coordinate-stochastic super-resolution microscopy with the reversibly switchable fluorescent protein Dreiklang. ChemPhysChem 15 (4), pp. 756 - 762 (2014)

MPG.PuRe

78.

Journal Article

Lavoie-Cardinal, F.; Jensen, N. A.; Westphal, V.; Stiel, A. C.; Chmyrov, A.; Bierwagen, J.; Testa, I.; Jakobs, S.; Hell, S. W.: Two-color RESOLFT nanoscopy with green and red fluorescent photochromic proteins. ChemPhysChem 15 (4), pp. 655 - 663 (2014)

MPG.PuRe

publisher-version

supplementary-material

79.

Journal Article

Stagge, F.; Mitronova, G.; Belov, V. N.; Wurm, C. A.; Jakobs, S.: Snap-, CLIP- and Halo-tag labelling of budding yeast cells. PLoS One 8 (10), e78745 (2013)

MPG.PuRe

publisher-version

80.

Journal Article

Chmyrov, A.; Keller, J.; Grotjohann, T.; Ratz, M.; d'Este, E.; Jakobs, S.; Eggeling, C.; Hell, S. W.: Nanoscopy with more than 100,000 'doughnuts'. Nature methods 10, pp. 737 - 740 (2013)

MPG.PuRe

publisher-version

supplementary-material

81.

Journal Article

Jans, D. C.; Wurm, C. A.; Riedel, D.; Wenzel, D.; Stagge, F.; Deckers, M.; Rehling, P.; Jakobs, S.: STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria. Proceedings of the National Academy of Sciences of the United States of America 110 (22), pp. 8936 - 8941 (2013)

MPG.PuRe

publisher-version

supplementary-material

82.

Journal Article

Grotjohann, T.; Testa, I.; Reuss, M.; Brakemann, T.; Eggeling, C.; Hell, S. W.; Jakobs, S.: rsEGFP2 enables fast RESOLFT nanoscopy of living cells. eLife 1, e00248 (2012)

MPG.PuRe

publisher-version

83.

Journal Article

Kolmakov, K.; Wurm, C. A.; Henning, R.; Rapp, E.; Jakobs, S.; Belov, V. N.; Hell, S. W.: Red-emitting rhodamines with hydroxylated, sulfonated, and phosphorylated dye residues and their use in fluorescence nanoscopy. Chemistry-A European Journal 18 (41), pp. 12986 - 12998 (2012)

MPG.PuRe

supplementary-material

84.

Journal Article

Wurm, C. A.; Kolmakov, K.; Göttfert, F.; Ta, H.; Bossi, M. L.; Schill, H.; Berning, S.; Jakobs, S.; Donnert, G.; Belov, V. N. et al.; Hell, S. W.: Novel red fluorophores with superior performance in STED microscopy. Optical Nanoscopy 1, 7 (2012)

MPG.PuRe

publisher-version

85.

Journal Article

Testa, I.; Urban, N.; Jakobs, S.; Eggeling, C.; Willig, K. I.; Hell, S. W.: Nanoscopy of living brain slices with low light levels. Neuron 75 (6), pp. 992 - 1000 (2012)

MPG.PuRe

publisher-version

supplementary-material

86.

Journal Article

Stoldt, S.; Wenzel, D.; Hildenbeutel, M.; Wurm, C. A.; Hermann, J. M.; Jakobs, S.: The inner-mitochondrial distribution of Oxa1 depends on the growth conditions and on the availability of substrates. Molecular Biology of the Cell 23 (12), pp. 2292 - 2301 (2012)

MPG.PuRe

publisher-version

supplementary-material

87.

Journal Article

Vukotic, M.; Oeljeklaus, S.; Wiese, S.; Voegtle, F. N.; Meisinger, C.; Meyer, H. E.; Zieseniss, A.; Katschienski, D. M.; Jans, D. C.; Jakobs, S. et al.; Warscheid, B.; Rehling, P.; Deckers, M.: Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex. Cell Metabolism 15 (3), pp. 336 - 347 (2012)

MPG.PuRe

publisher-version

supplementary-material

88.

Journal Article

Alkhaja, A. K.; Jans, D. C.; Nikolov, M.; Vukotic, M.; Lytovchenko, O.; Ludewig, F.; Schliebs, W.; Riedel, D.; Urlaub, H.; Jakobs, S. et al.; Deckers, M.: MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. Molecular Biology of the Cell 23 (2), pp. 247 - 257 (2012)

MPG.PuRe

publisher-version

89.

Journal Article

Kleine-Vehn, J.; Wabnik, K.; Martiniere, A.; Langowski, L.; Willig, K.; Naramoto, S.; Leitner, J.; Tanaka, H.; Jakobs, S.; Robert, S. et al.; Luschnig, C.; Govaerts, W.; Hell, S. W.; Runions, J.; Friml, J.: Recycling, clustering, and endocytosis jointly maintain PIN auxin carrier polarity at the plasma membrane. Molecular Systems Biology 7, 540 (2011)

MPG.PuRe

90.

Journal Article

Grotjohann, T.; Testa, I.; Leutenegger, M.; Bock, H.; Urban, N.; Lavoie-Cardinal, F.; Willig, K.; Eggeling, C.; Jakobs, S.; Hell, S. W.: Diffraction-unlimited all-optical imaging and writing with a photochromic GFP. Nature 478 (7368), pp. 204 - 208 (2011)

MPG.PuRe

91.

Journal Article

Brakemann, T.; Stiel, A. C.; Weber, G.; Andresen, M.; Testa, I.; Grotjohann., T.; Leutenegger, M.; Plessmann, U.; Urlaub, H.; Eggeling, C. et al.; Wahl, M. C.; Hell, S. W.; Jakobs, S.: A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nature biotechnology 29 (10), pp. 942 - 947 (2011)

MPG.PuRe

publisher-version

publisher-version

92.

Journal Article

Wurm, C. A.; Neumann, D.; Lauterbach, M.; Harke, B.; Egner, A.; Hell, S. W.; Jakobs, S.: Nanoscale distribution of mitochondrial import receptor Tom20 is adjusted to cellular conditions and exhibits an inner-cellular gradient. Proceedings of the National Academy of Sciences of the United States of America 108 (33), pp. 13546 - 13551 (2011)

MPG.PuRe

publisher-version

publisher-version

93.

Journal Article

Kukat, C.; Wurm, C. A.; Spahr, H.; Falkenberg, M.; Larsson, N. G.; Jakobs, S.: Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA. Proceedings of the National Academy of Sciences of the United States of America 108 (33), pp. 13534 - 13539 (2011)

MPG.PuRe

publisher-version

publisher-version

94.

Journal Article

Willig, K.; Stiel, A. C.; Brakemann, T.; Jakobs, S.; Hell, S. W.: Dual-label STED nanoscopy of living cells using photochromism. Nano Letters 11 (9), pp. 3970 - 3973 (2011)

MPG.PuRe

publisher-version

publisher-version

95.

Journal Article

Testa, I.; Wurm, C. A.; Medda, R.; Rothermel, E.; von Middendorff, C.; Foelling, J.; Jakobs, S.; Schoenle, A.; Hell, S. W.; Eggeling, C.: Multicolor fluorescence nanoscopy in fixed and living cells by exciting conventional fluorophores with a single wavelength. Biophysical Journal 99 (8), pp. 2686 - 2694 (2010)

MPG.PuRe

publisher-version

96.

Journal Article

Bierwagen, J.; Testa, I.; Foelling, J.; Wenzel, D.; Jakobs, S.; Eggeling, C.; Hell, S. W.: Far-field autofluorescence nanoscopy. Nano Letters 10 (10), pp. 4249 - 4252 (2010)

MPG.PuRe

publisher-version

97.

Journal Article

Wurm, C. A.; Suppanz, I.; Stoldt, S.; Jakobs, S.: Rapid FlAsH labelling in the budding yeast Saccharomyces cerevisiae. Journal of Microscopy 240 (1), pp. 6 - 13 (2010)

MPG.PuRe

98.

Journal Article

Brakemann, T.; Weber, G.; Andresen, M.; Groenhof, G.; Stiel, A. C.; Trowitzsch, S.; Eggeling, C.; Grubmueller, H.; Hell, S. W.; Wahl, M. et al.; Jakobs, S.: Molecular basis of the light-driven switching of the photochromic fluorescent protein padron. Journal of Biological Chemistry 285 (19), pp. 14603 - 14609 (2010)

MPG.PuRe

publisher-version

99.

Journal Article

Belov, V.; Wurm, C. A.; Boyarskiy, V. P.; Jakobs, S.; Hell, S. W.: Rhodamines NN: A novel class of caged fluorescent dyes. Angewandte Chemie International Edition 49 (20), pp. 3520 - 3523 (2010)

MPG.PuRe