Max Planck Institute for Multidisciplinary Sciences

Publications

Journal Article (40)

1.

Journal Article

Michanski, S.; Kapoor, R.; Steyer, A. M.; Möbius, W.; Früholz, I.; Ackermann, F.; Gueltas, M.; Garner, C. C.; Hamra, F. K.; Neef, J. et al.; Strenzke, N.; Moser, T.; Wichmann, C.: Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing. EMBO Reports 24 (9), e56702 (2023)

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2.

Journal Article

Grabner, C.; Futagi, D.; Shi, J.; Bindokas, V.; Kitano, K.; Schwartz, E.A.; DeVries, S.H.: Mechanisms of simultaneous linear and nonlinear computations at the mammalian cone photoreceptor synapse. Nature Communications 14, 3486 (2023)

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3.

Journal Article

Zerche, M.; Wrobel, C.; Kusch, K.; Moser, T.; Mager, T.: Channelrhodopsin fluorescent tag replacement for clinical translation of optogenetic hearing restoration. Molecular Therapy: Methods & Clinical Development 29, pp. 202 - 212 (2023)

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4.

Journal Article

Hunniford, V.; Kuehler, R.; Wolf, B.; Keppeler, D.; Strenzke, N.; Moser, T.: Patient perspectives on the need for improved hearing rehabilitation: A qualitative survey study of German cochlear implant users. Frontiers in Neuroscience 17, 1105562 (2023)

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5.

Journal Article

Cantu-Guerra, H. L.; Papazian, M. R.; Gorsky, A. L.; Alekos, N. S.; Caccavano, A.; Karagulyan, N.; Neef, J.; Vicini, S.; Moser, T.; Coate, T. M.: Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3A. Developmental Dynamics 252 (1), pp. 124 - 144 (2023)

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6.

Journal Article

Mittring, A.; Moser, T.; Huet, A. T.: Graded optogenetic activation of the auditory pathway for hearing restoration. Brain Stimulation 16 (2), pp. 466 - 483 (2023)

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7.

Journal Article

Chakrabarti, R.; Jaime Tobon, L. M.; Slitin, L.; Redondo-Canales, M.; Hoch, G.; Slashcheva, M.; Fritsch, E.; Bodensiek, K.; Özçete, Ö. D.; Gültas, M. et al.; Michanski, S.; Opazo, F.; Neef, J.; Pangrsic, T.; Moser, T.; Wichmann, C.: Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses. eLife 11, e79494 (2022)

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8.

Journal Article

Bosse, N. I.; Abbott, S.; Bracher, J.; Hain, H.; Quilty, B. J.; Jit, M.; Centre for the Mathematical Modelling of Infectious Diseases COVID-19 Working Group; van Leeuwen, E.; Cori, A.; Funk, S.: Comparing human and model-based forecasts of COVID-19 in Germany and Poland. PLoS Computational Biology 18 (9), e1010405 (2022)

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9.

Journal Article

Wolf, B. J.; Kusch, K.; Hunniford, V.; Vona, B.; Kuhler, R.; Keppeler, D.; Strenzke, N.; Moser, T.: Is there an unmet medical need for improved hearing restoration? Embo Molecular Medicine 14 (8), e15798 (2022)

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10.

Journal Article

Grabner, C.; Jansen, I.; Neef, J.; Weihs, T.; Schmidt, R.; Riedel, D.; Wurm, C. A.; Moser, T.: Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX. Science Advances 8 (28), eabl7560 (2022)

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11.

Journal Article

Calapai, A.; Cabrera-Moreno, J.; Moser, T.; Jeschke, M.: Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system. Nature Communications 13 (1), 1648 (2022)

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12.

Journal Article

Khurana, L.; Keppeler, D.; Jablonski, L.; Moser, T.: Model-based prediction of optogenetic sound encoding in the human cochlea by future optical cochlear implants. Computational and Structural Biotechnology Journal 20, pp. 3621 - 3629 (2022)

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13.

Journal Article

Butola, T.; Alvanos, T.; Hintze, A.; Koppensteiner, P.; Kleindienst, D.; Shigemoto, R.; Wichmann, C.; Moser, T.: RIM-Binding Protein 2 organizes Ca2+channel topography and regulates release probability and vesicle replenishment at a fast central synapse. bioRxiv, 435607 (2021)

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14.

Journal Article

Özçete, Ö. D.; Moser, T.: A sensory cell diversifies its output by varying Ca2+ influx‐release coupling among active zones. EMBO Journal 40 (5), e106010 (2021)

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15.

Journal Article

Rankovic, V.; Vogl, C.; Dörje, N. M.; Bahader, I.; Duque-Afonso, C. J.; Thirumalai, A.; Weber, T.; Kusch, K.; Strenzke, N.; Moser, T.: Overloaded adeno-associated virus as a novel gene therapeutic tool for otoferlin-related deafness. Frontiers in Moecular Neuroscience 13, 600051 (2021)

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16.

Journal Article

Grabner, C.; Moser, T.: The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast fusion of the readily releasable pool of vesicles. bioRxiv, 336503 (2020)

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17.

Journal Article

Keppeler, D.; Schwaerzle, M.; Harczos, T.; Jablonski, L.; Dieter, A.; Wolf, B.; Ayub, S.; Vogl, C.; Wrobel, C.; Hoch, G. et al.; Abdellatif, K.; Jeschke, M.; Rankovic, V.; Paul, O.; Ruther, P.; Moser, T.: Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents. Science Translational Medicine 12 (553), eabb8086 (2020)

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18.

Journal Article

Kroll, J.; Özçete, Ö. D.; Jung, S.; Maritzen, T.; Milosevic, I.; Wichmann, C.; Moser, T.: AP180 promotes release site clearance and clathrin-dependent vesicle reformation in mouse cochlear inner hair cells. Journal of Cell Science 133 (2), jcs236737 (2020)

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19.

Journal Article

Michanski, S.; Smaluch, K.; Steyer, A. M.; Chakrabarti, R.; Setz, C.; Oestreicher, D.; Fischer, C.; Möbius, W.; Moser, T.; Vogl, C. et al.; Wichmann, C.: Mapping developmental maturation of inner hair cell ribbon synapses in the apical mouse cochlea. Proceedings of the National Academy of Sciences of the United States of America 116 (13), pp. 6415 - 6424 (2019)

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20.

Journal Article

Kroll, J.; Jaime Tobon, L. M.; Vogl, C.; Neef, J.; Kondratiuk, I.; König, M.; Strenzke, N.; Wichmann, C.; Milosevic, I.; Moser, T.: Endophilin-A regulates presynaptic Ca2⁺ influx and synaptic vesicle recycling in auditory hair cells. The EMBO Journal 38 (5), e100116 (2019)

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21.

Journal Article

Takago, H.; Oshima-Takago, T.; Moser, T.: Disruption of otoferlin alters the mode of exocytosis at the mouse inner hair cell ribbon synapse. Frontiers in Molecular Neuroscience 11, 492 (2019)

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22.

Journal Article

Al‐Moyed, H.; Cepeda, A. P.; Jung, S.; Moser, T.; Kügler, S.; Reisinger, E.: A dual-AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock-out mice. EMBO Molecular Medicine 10 (12), e9396 (2018)

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23.

Journal Article

Grabner, C.; Moser, T.: Individual synaptic vesicles mediate stimulated exocytosis from cochlear inner hair cells. Proceedings of the National Academy of Sciences of the United States of America 115 (50), pp. 12811 - 12816 (2018)

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24.

Journal Article

Hagiwara, A.; Kitahara, Y.; Grabner, C.; Vogl, C.; Abe, M.; Kitta, R.; Ohta, K.; Nakamura, K.; Sakimura, K.; Moser, T. et al.; Nishi, A.; Ohtsuka, T.: Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance. Journal of Cell Biology 217 (11), pp. 3993 - 4006 (2018)

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25.

Journal Article

Brandenburg, S.; Pawlowitz, J.; Fakuade, F. E.; Kownatzki-Danger, D.; Kohl, T.; Mitronova, G.; Scardigli, M.; Neef, J.; Schmidt, C.; Wiedmann, F. et al.; Pavone, F. S.; Sacconi, L.; Kutschka, I.; Sossalla, S.; Moser, T.; Voigt, N.; Lehnart, S. E.: Axial tubule junctions activate atrial Ca²⁺ release across species. Frontiers in Physiology 9, 1227 (2018)

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26.

Journal Article

Mager, T.; de la Morena, D. L.; Senn, V.; Schlotte, J.; D´Errico, A.; Feldbauer, K.; Wrobel, C.; Jung, S.; Bodensiek, K.; Rankovic, V. et al.; Browne, L.; Huet, A.; Jüttner, J.; Wood, P. G.; Letzkus, J. J.; Moser, T.; Bamberg, E.: High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics. Nature Communications 9, 1750 (2018)

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supplementary-material

27.

Journal Article

Neef, J.; Urban, N. T.; Ohn, T. L.; Frank, T.; Jean, P.; Hell, S. W.; Willig, K. I.; Moser, T.: Quantitative optical nanophysiology of Ca²⁺ signaling at inner hair cell active zones. Nature Communications 9, 290 (2018)

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28.

Journal Article

Richter, K. N.; Revelo, N. H.; Seitz, K. J.; Helm, M. S.; Sarkar, D.; Saleeb, R. S.; D'Este, E.; Eberle, J.; Wagner, E.; Vogl, C. et al.; Lazaro, D. F.; Richter, F.; Coy‐Vergara, J.; Coceano, G.; Boyden, E. S.; Duncan, R. R.; Hell, S. W.; Lauterbach, M. A.; Lehnart, S. E.; Moser, T.; Outeiro, T.; Rehling, P.; Schwappach, B.; Testa, I.; Zapiec, B.; Rizzoli, S. O.: Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy. EMBO Journal 37 (1), pp. 139 - 159 (2018)

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29.

Journal Article

Krinner, S.; Butola, T.; Jung, S.; Wichmann, C.; Moser, T.: RIM-binding protein 2 promotes a large number of Ca_V1.3 Ca²⁺-channels and contributes to fast synaptic vesicle replenishment at hair cell active zones. Frontiers in Cellular Neuroscience 11, 334 (2017)

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30.

Journal Article

Vogl, C.; Butola, T.; Haag, N.; Hausrat, T. J.; Leitner, M. G.; Moutschen, M.; Lefebvre, P. P.; Speckmann, C.; Garrett, L.; Becker, L. et al.; Fuchs, H.; de Angelis, M. H.; Nietzsche, S.; Kessels, M. M.; Oliver, D.; Kneussel, M.; Kilimann, M. W.; Strenzke, N.: The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing. EMBO Reports 18 (11), pp. 2015 - 2029 (2017)

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31.

Journal Article

Butola, T.; Wichmann, C.; Moser, T.: Piccolo promotes vesicle replenishment at a fast central auditory synapse. Frontiers in Synaptic Neuroscience 9, 14 (2017)

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32.

Journal Article

Picher, M. M.; Oprişoreanu, A. M.; Jung, S.; Michel, K.; Schoch, S.; Moser, T.: Rab interacting molecules 2 and 3 directly interact with the pore-forming CaV1.3 Ca²⁺ channel subunit and promote its membrane expression. Frontiers in Cellular Neuroscience 11, 160, pp. 160-1 - 160-11 (2017)

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33.

Journal Article

Picher, M. M.; Gehrt, A.; Meese, S.; Ivanovic, A.; Predoehl, F.; Jung, S.; Schrauwen, I.; Dragonetti, A. G.; Colombo, R.; Van Camp, G. et al.; Strenzke, N.; Moser, T.: Ca²⁺-binding protein 2 inhibits Ca²⁺-channel inactivation in mouse inner hair cells. Proceedings of the National Academy of Sciences of the United States of America 114 (9), pp. E1717 - E1726 (2017)

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34.

Journal Article

Vogl, C.; Panou, I.; Yamanbaeva, G.; Wichmann, C.; Mangosing, S. J.; Vilardi, F.; Indzhykulian, A. A.; Pangršič, T.; Santarelli, R.; Rodriguez-Ballesteros, M. et al.; Weber, T.; Jung, S.; Cardenas, E.; Wu, X.; Wojcik, S. M.; Kwan, K. Y.; Del Castillo, I.; Schwappach, B.; Strenzke, N.; Corey, D. P.; Lin, S. Y.; Moser, T.: Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing. The EMBO Journal 35 (23), pp. 2536 - 2552 (2016)

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35.

Journal Article

Moser, T.; Vogel, C.: New insights into cochlear sound encoding. F1000Research 5, 2081 (2016)

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36.

Journal Article

Ohn, T. L.; Rutherford, M. A.; Jing, Z.; Jung, S.; Duque-Afonso, C. J.; Hoch, G.; Picher, M. M.; Scharinger, A.; Strenzke, A.; Moser, T.: Hair cells use active zones with different voltage dependence of Ca²⁺ influx to decompose sounds into complementary neural codes. Proceedings of the National Academy of Sciences of the United States of America 113 (32), pp. E4716 - E4725 (2016)

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37.

Journal Article

Grabner, C.; Ratliff, C. P.; Light, A. C.; DeVries, S. H.: Mechanism of high-frequency signaling at a depressing ribbon synapse. Neuron 91 (1), pp. 133 - 145 (2016)

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38.

Journal Article

Moser, T.: Eyes without a ribbon. EMBO Journal 35 (10), pp. 1018 - 1020 (2016)

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39.

Journal Article

Jung, S.; Maritzen, T.; Wichmann, C.; Jing, Z.; Neef, A.; Revelo, N. H.; Al‐Moyed, H.; Meese, S.; Wojcik, S. M.; Panou, I. et al.; Bulut, H.; Schu, P.; Ficner, R.; Reisinger, E.; Rizzoli, S. O.; Neef, J.; Strenzke, N.; Haucke, V.; Moser, T.: Disruption of adaptor protein 2μ (AP‐2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing. EMBO Journal 34 (21), pp. 2686 - 2702 (2015)

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40.

Journal Article

Moser, T.: Gene therapy for deafness: How close are we? Science Translational Medicine 7 (295), 295fs28 (2015)

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Book Chapter (1)

41.

Book Chapter

Moser, T.: Presynaptic physiology of cochlear inner hair cells. In: The Senses., Vol. 2, 2. Ed., pp. 441 - 467 (Ed. Fritzsch, B.). Elsevier, San Diego, Calif. (2020)

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