Publications
Journal Article (49)
1.
Journal Article
17, 1351280 (2024)
Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse. Frontiers in Molecular Neuroscience 2.
Journal Article
23 (2), 100704 (2024)
Proteomic Analysis Reveals the Composition of Glutamatergic Organelles of Auditory Inner Hair Cells. Molecular & Cellular Proteomics 3.
Journal Article
16, 1299509 (2023)
Probing the role of the C2F domain of otoferlin. Frontiers in Molecular Neuroscience 4.
Journal Article
Ca2+ binding to the C2E domain of otoferlin is required for hair cell exocytosis and hearing. Protein & Cell, pwad058 (2023)
5.
Journal Article
42 (23), e114587 (2023)
Diversity matters — extending sound intensity coding by inner hair cells via heterogeneous synapses. The EMBO Journal 6.
Journal Article
26 (10), 107725 (2023)
En route to sound coding strategies for optical cochlear implants. iScience 7.
Journal Article
16, 1248941 (2023)
Synaptic activity is not required for establishing heterogeneity of inner hair cell ribbon synapses. Frontiers in Molecular Neuroscience 8.
Journal Article
24 (9), e56702 (2023)
Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing. EMBO Reports 9.
Journal Article
14, 3486 (2023)
Mechanisms of simultaneous linear and nonlinear computations at the mammalian cone photoreceptor synapse. Nature Communications 10.
Journal Article
29, pp. 202 - 212 (2023)
Channelrhodopsin fluorescent tag replacement for clinical translation of optogenetic hearing restoration. Molecular Therapy: Methods & Clinical Development 11.
Journal Article
17, 1105562 (2023)
Patient perspectives on the need for improved hearing rehabilitation: A qualitative survey study of German cochlear implant users. Frontiers in Neuroscience 12.
Journal Article
252 (1), pp. 124 - 144 (2023)
Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3A. Developmental Dynamics 13.
Journal Article
120 (49), e2311539120 (2023)
Ca2+ regulation of glutamate release from inner hair cells of hearing mice. Proceedings of the National Academy of Sciences of the United States of America 14.
Journal Article
16 (5), pp. 1486 - 1500 (2023)
Devising a framework of optogenetic coding in the auditory pathway: Insights from auditory midbrain recordings. Brain Stimulation 15.
Journal Article
16 (2), pp. 466 - 483 (2023)
Graded optogenetic activation of the auditory pathway for hearing restoration. Brain Stimulation 16.
Journal Article
11, e79494 (2022)
Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses. eLife 17.
Journal Article
18 (9), e1010405 (2022)
Comparing human and model-based forecasts of COVID-19 in Germany and Poland. PLoS Computational Biology 18.
Journal Article
14 (8), e15798 (2022)
Is there an unmet medical need for improved hearing restoration? Embo Molecular Medicine 19.
Journal Article
8 (28), eabl7560 (2022)
Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX. Science Advances 20.
Journal Article
13 (1), 1648 (2022)
Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system. Nature Communications 21.
Journal Article
20, pp. 3621 - 3629 (2022)
Model-based prediction of optogenetic sound encoding in the human cochlea by future optical cochlear implants. Computational and Structural Biotechnology Journal 22.
Journal Article
RIM-Binding Protein 2 organizes Ca2+channel topography and regulates release probability and vesicle replenishment at a fast central synapse. bioRxiv, 435607 (2021)
23.
Journal Article
40 (5), e106010 (2021)
A sensory cell diversifies its output by varying Ca2+ influx‐release coupling among active zones. EMBO Journal 24.
Journal Article
13, 600051 (2021)
Overloaded adeno-associated virus as a novel gene therapeutic tool for otoferlin-related deafness. Frontiers in Moecular Neuroscience 25.
Journal Article
The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast fusion of the readily releasable pool of vesicles. bioRxiv, 336503 (2020)
26.
Journal Article
12 (553), eabb8086 (2020)
Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents. Science Translational Medicine 27.
Journal Article
133 (2), jcs236737 (2020)
AP180 promotes release site clearance and clathrin-dependent vesicle reformation in mouse cochlear inner hair cells. Journal of Cell Science 28.
Journal Article
116 (13), pp. 6415 - 6424 (2019)
Mapping developmental maturation of inner hair cell ribbon synapses in the apical mouse cochlea. Proceedings of the National Academy of Sciences of the United States of America 29.
Journal Article
38 (5), e100116 (2019)
Endophilin-A regulates presynaptic Ca2+ influx and synaptic vesicle recycling in auditory hair cells. The EMBO Journal 30.
Journal Article
11, 492 (2019)
Disruption of otoferlin alters the mode of exocytosis at the mouse inner hair cell ribbon synapse. Frontiers in Molecular Neuroscience 31.
Journal Article
10 (12), e9396 (2018)
A dual-AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock-out mice. EMBO Molecular Medicine 32.
Journal Article
115 (50), pp. 12811 - 12816 (2018)
Individual synaptic vesicles mediate stimulated exocytosis from cochlear inner hair cells. Proceedings of the National Academy of Sciences of the United States of America 33.
Journal Article
217 (11), pp. 3993 - 4006 (2018)
Cytomatrix proteins CAST and ELKS regulate retinal photoreceptor development and maintenance. Journal of Cell Biology 34.
Journal Article
9, 1227 (2018)
Axial tubule junctions activate atrial Ca2+ release across species. Frontiers in Physiology 35.
Journal Article
9, 1750 (2018)
High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics. Nature Communications 36.
Journal Article
9, 290 (2018)
Quantitative optical nanophysiology of Ca2+ signaling at inner hair cell active zones. Nature Communications 37.
Journal Article
37 (1), pp. 139 - 159 (2018)
Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy. EMBO Journal 38.
Journal Article
11, 334 (2017)
RIM-binding protein 2 promotes a large number of CaV1.3 Ca2+-channels and contributes to fast synaptic vesicle replenishment at hair cell active zones. Frontiers in Cellular Neuroscience 39.
Journal Article
18 (11), pp. 2015 - 2029 (2017)
The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing. EMBO Reports 40.
Journal Article
9, 14 (2017)
Piccolo promotes vesicle replenishment at a fast central auditory synapse. Frontiers in Synaptic Neuroscience 41.
Journal Article
11, 160, pp. 160-1 - 160-11 (2017)
Rab interacting molecules 2 and 3 directly interact with the pore-forming CaV1.3 Ca2+ channel subunit and promote its membrane expression. Frontiers in Cellular Neuroscience 42.
Journal Article
114 (9), pp. E1717 - E1726 (2017)
Ca2+-binding protein 2 inhibits Ca2+-channel inactivation in mouse inner hair cells. Proceedings of the National Academy of Sciences of the United States of America 43.
Journal Article
35 (23), pp. 2536 - 2552 (2016)
Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing. The EMBO Journal 44.
Journal Article
5, 2081 (2016)
New insights into cochlear sound encoding. F1000Research 45.
Journal Article
113 (32), pp. E4716 - E4725 (2016)
Hair cells use active zones with different voltage dependence of Ca2+ influx to decompose sounds into complementary neural codes. Proceedings of the National Academy of Sciences of the United States of America 46.
Journal Article
91 (1), pp. 133 - 145 (2016)
Mechanism of high-frequency signaling at a depressing ribbon synapse. Neuron 47.
Journal Article
35 (10), pp. 1018 - 1020 (2016)
Eyes without a ribbon. EMBO Journal 48.
Journal Article
34 (21), pp. 2686 - 2702 (2015)
Disruption of adaptor protein 2μ (AP‐2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing. EMBO Journal 49.
Journal Article
7 (295), 295fs28 (2015)
Gene therapy for deafness: How close are we? Science Translational Medicine Book Chapter (1)
50.
Book Chapter
2, 2. Ed., pp. 441 - 467 (Ed. Fritzsch, B.). Elsevier, San Diego, Calif. (2020)
Presynaptic physiology of cochlear inner hair cells. In: The Senses., Vol.