Publications

1.

Journal Article

Frieg, B.; Antonschmidt, L.; Dienemann, C.; Geraets, J. A.; Najbauer, E. E.; Matthes, D.; de Groot, B. L.; Andreas, L. B.; Becker, S.; Griesinger, C. et al.; Schröder, G. F.: The 3D structure of lipidic fibrils of α-synuclein. Nature Communications 13 (1), 6810 (2022)

MPG.PuRe

DOI

publisher-version

2.

Journal Article

Kaur, N.; Fischer, M.; Hitaishi, P.; Kumar, S.; Sharma, V. K.; Ghosh, S. K.; Gahlay, G. K.; Scheidt, H. A.; Mithu, V. S.: How 1,n-Bis(3-alkylimidazolium-1-yl) Alkane Interacts with the Phospholipid Membrane and Impacts the Toxicity of Dicationic Ionic Liquids. Langmuir 38 (45), pp. 13803 - 13813 (2022)

MPG.PuRe

DOI

3.

Journal Article

de Opakua, A. I.; Geraets, J. A.; Frieg, B.; Dienemann, C.; Savastano, A.; Rankovic, M.; Cima-Omori, M.-S.; Schröder, G. F.; Zweckstetter, M.: Molecular interactions of FG nucleoporin repeats at high resolution. Nature Chemistry 14, pp. 1278 - 1285 (2022)

MPG.PuRe

DOI

publisher-version

4.

Journal Article

Rafiei, Y.; Salmani, B.; Mirzaei-Behbahani, B.; Taleb, M.; Meratan, A. A.; Ramezani, M.; Nikfarjam, N.; Becker, S.; Rezaei-Ghaleh, N.: Polyphenols-Based Nanosheets of Propolis Modulate Cytotoxic Amyloid Fibril Assembly of α-Synuclein. ACS Chemical Neuroscience 13 (22), pp. 3168 - 3179 (2022)

MPG.PuRe

DOI

5.

Journal Article

Sieme, D.; Griesinger, C.; Rezaei-Ghaleh, N.: Metal Binding to Sodium Heparin Monitored by Quadrupolar NMR. International Journal of Molecular Sciences 23 (21), 13185 (2022)

MPG.PuRe

DOI

publisher-version

6.

Journal Article

Sang, D.; Shu, T.; Pantoja, C. F.; de Opakua, A. I.; Zweckstetter, M.; Holt, L. J.: Condensed-phase signaling can expand kinase specificity and respond to macromolecular crowding. Molecular Cell 82 (19), pp. 3693 - 3711.e10 (2022)

MPG.PuRe

DOI

publisher-version

7.

Journal Article

Frieg, B.; Geraets, J. A.; Strohaeker, T.; Dienemann, C.; Mavroeidi, P.; Jung, B. C.; Kim, W. S.; Lee, S.-J.; Xilouri, M.; Zweckstetter, M. et al.; Schroeder, G. F.: Quaternary structure of patient-homogenate amplified α-synuclein fibrils modulates seeding of endogenous α-synuclein. Communications Biology 5 (1), 1040 (2022)

MPG.PuRe

DOI

publisher-version

8.

Journal Article

Antonschmidt, L.; Matthes, D.; Dervişoğlu, R.; Frieg, B.; Dienemann, C.; Leonov, A.; Nimerovsky, E.; Sant, V.; Ryazanov, S.; Giese, A. et al.; Schröder, G.; Becker, S.; de Groot, B. L.; Griesinger, C.; Andreas, L. B.: The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils. Nature Communications 13, 5385 (2022)

MPG.PuRe

DOI

publisher-version

9.

Journal Article

Karschin, N.; Becker, S.; Griesinger, C.: Interdomain Dynamics via Paramagnetic NMR on the Highly Flexible Complex Calmodulin/Munc13-1. Journal of the American Chemical Society 144 (37), pp. 17041 - 17053 (2022)

MPG.PuRe

DOI

publisher-version

10.

Journal Article

Babu, M.; Favretto, F.; Rankovic, M.; Zweckstetter, M.: Peptidyl Prolyl Isomerase A Modulates the Liquid–Liquid Phase Separation of Proline-Rich IDPs. Journal of the American Chemical Society 144 (35), pp. 16157 - 16163 (2022)

MPG.PuRe

DOI

publisher-version

11.

Journal Article

Zachrdla, M.; Savastano, A.; de Opakua, A. I.; Cima-Omori, M.-S.; Zweckstetter, M.: Contributions of the N-terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA-induced phase separation. Protein Science 31 (9), e4409 (2022)

MPG.PuRe

DOI

publisher-version

12.

Journal Article

Acevedo-Garcia, J.; Walden, K.; Leissing, F.; Baumgarten, K.; Drwiega, K.; Kwaaitaal, M.; Reinstädler, A.; Freh, M.; Dong, X.; James, G. V. et al.; Baus, L. C.; Mascher, M.; Stein, N.; Schneeberger, K.; Brocke-Ahmadinejad, N.; Kollmar, M.; Schulze-Lefert, P.; Panstruga, R.: Barley Ror1 encodes a class XI myosin required for mlo-based broad-spectrum resistance to the fungal powdery mildew pathogen. The Plant Journal 112 (1), pp. 84 - 103 (2022)

MPG.PuRe

DOI

publisher-version

13.

Journal Article

Fuentes-Monteverde, J. C.; Nath, N.; Forero, A. M.; Balboa, E. M.; Navarro-Vazquez, A.; Griesinger, C.; Jimenez, C.; Rodriguez, J.: Connection of Isolated Stereoclusters by Combining ¹³C-RCSA, RDC, and J-Based Configurational Analyses and Structural Revision of a Tetraprenyltoluquinol Chromane Meroterpenoid from Sargassum muticum. Marine Drugs 20 (7), 462 (2022)

MPG.PuRe

DOI

publisher-version

14.

Journal Article

Buratti, F. A.; Boeffinger, N.; Garro, H. A.; Flores, J. S.; Hita, F. J.; Gonçalves, P. d. C.; Copello, F. d. R.; Lizarraga, L.; Rossetti, G.; Carloni, P. et al.; Zweckstetter, M.; Outeiro, T. F.; Eimer, S.; Griesinger, C.; Fernández, C. O.: Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations. Protein Science 31 (7), e4360 (2022)

MPG.PuRe

DOI

publisher-version

15.

Journal Article

Ding, Y.; Korchak, S.; Mamone, S.; Jagtap, A. P.; Stevanato, G.; Sternkopf, S.; Moll, D.; Schroeder, H.; Becker, S.; Fische, A. et al.; Gerhardt, E.; Outeiro, T. F.; Opazo, F.; Griesinger, C.; Glöggler, S.: Rapidly signal‐enhanced metabolites for atomic scale monitoring of living cells with magnetic resonance. Chemistry–Methods 2 (7), e202200023 (2022)

MPG.PuRe

DOI

publisher-version

16.

Journal Article

Pech-Puch, D.; Forero, A. M.; Fuentes-Monteverde, J. C.; Lasarte-Monterrubio, C.; Martinez-Guitian, M.; González-Salas, C.; Guillén-Hernández, S.; Villegas-Hernández, H.; Beceiro, A.; Griesinger, C. et al.; Rodríguez, J.; Jiménez, C.: Antimicrobial diterpene alkaloids from an Agelas Citrina sponge collected in the Yucatán Peninsula. Marine Drugs 20 (5), 298 (2022)

MPG.PuRe

DOI

publisher-version

17.

Journal Article

Luebben, A. V.; Bender, D.; Becker, S.; Crowther, L. M.; Erven, I.; Hofmann, K.; Söding, J.; Klemp, H.; Bellotti, C.; Stäuble, A. et al.; Qiu, T.; Kathayat, R. S.; Dickinson, B. C.; Gärtner, J.; Sheldrick, G. M.; Krätzner, R.; Steinfeld, R.: Cln5 represents a new type of cysteine-basedS-depalmitoylase linked to neurodegeneration. Science Advances 8 (15), eabj8633 (2022)

MPG.PuRe

DOI

publisher-version

18.

Journal Article

Kumar, S. T.; Mahul-Mellier, A.-L.; Hegde, R. N.; Riviere, G.; Moons, R.; de Opakua, A. I.; Magalhaes, P.; Rostami, I.; Donzelli, S.; Sobott, F. et al.; Zweckstetter, M.; Lashuel, H. A.: A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity. Science Advances 8 (17), eabn0044 (2022)

MPG.PuRe

DOI

publisher-version

19.

Journal Article

Min, J.-O.; Strohäker, T.; Jeong, B.-C.; Zweckstetter, M.; Lee, S.-J.: Chicago sky blue 6B inhibits α-synuclein aggregation and propagation. Molecular Brain 15, 27 (2022)

MPG.PuRe

DOI

publisher-version

20.

Journal Article

Abyzov, A.; Blackledge, M.; Zweckstetter, M.: Conformational Dynamics of Intrinsically Disordered Proteins Regulate Biomolecular Condensate Chemistry. Chemical Reviews 122 (6), pp. 6719 - 6748 (2022)

MPG.PuRe

DOI

publisher-version

21.

Journal Article

Klose, D.; Vemulapalli, S. P.; Richman, M.; Rudnick, S.; Aisha, V.; Abayev, M.; Chemerovski, M.; Shviro, M.; Zitoun, D.; Majer, K. et al.; Wili, N.; Goobes, G.; Griesinger, C.; Jeschke, G.; Rahimipour, S.: Cu2+-induced self-assembly and amyloid formation of a cyclic d,l-α-peptide: Structure and function. Physical Chemistry Chemical Physics 24 (11), pp. 6699 - 6715 (2022)

MPG.PuRe

DOI

publisher-version

22.

Journal Article

Najbauer, E. E.; Ng, S. C.; Griesinger, C.; Görlich, D.; Andreas, L. B.: Atomic resolution dynamics of cohesive interactions in phase-separated Nup98 FG domains. Nature Communications 13, 1494 (2022)

MPG.PuRe

DOI

publisher-version

23.

Journal Article

Öster, C.; Tekwani Movellan, K.; Goold, B.; Hendriks, K.; Lange, S.; Becker, S.; de Groot, B. L.; Kopec, W.; Andreas, L. B.; Lange, A.: Direct detection of bound ammonium ions in the selectivity filter of ion channels by solid-state NMR. Journal of the American Chemical Society 144 (9), pp. 4147 - 4157 (2022)

MPG.PuRe

DOI

publisher-version

24.

Journal Article

Nedaei, H.; Rezaei-Ghaleh, N.; Giller, K.; Becker, S.; Karami, L.; Moosavi-Movahedi, A. A.; Griesinger, C.; Saboury, A. A.: The calcium-free form of atorvastatin inhibits amyloid-β(1–42) aggregation in vitro. Journal of Biological Chemistry 298 (3), 101662 (2022)

MPG.PuRe

DOI

publisher-version

25.

Journal Article

Najbauer, E. E.; Tekwani Movellan, K.; Giller, K.; Benz, R.; Becker, S.; Griesinger, C.; Andreas, L. B.: Structure and gating behavior of the human integral membrane protein VDAC1 in a lipid bilayer. Journal of the American Chemical Society 144 (7), pp. 2953 - 2967 (2022)

MPG.PuRe

DOI

publisher-version

26.

Journal Article

Robustelli, P.; Ibanez-de-Opakua, A.; Campbell-Bezat, C.; Giordanetto, F.; Becker, S.; Zweckstetter, M.; Pan, A. C.; Shaw, D. E.: Molecular Basis of Small-Molecule Binding to α-Synuclein. Journal of the American Chemical Society 144 (6), pp. 2501 - 2510 (2022)

MPG.PuRe

DOI

publisher-version

27.

Journal Article

Cario, A.; Savastano, A.; Wood, N. B.; Liu, Z.; Previs, M. J.; Hendricks, A. G.; Zweckstetter, M.; Berger, C. L.: The pathogenic R5L mutation disrupts formation of Tau complexes on the microtubule by altering local N-terminal structure. Proceedings of the National Academy of Sciences of the United States of America 119 (7), e2114215119 (2022)

MPG.PuRe

DOI

publisher-version

28.

Journal Article

Kim, M.; Ha, J.-H.; Choi, J.; Kim, B.-R.; Gapsys, V.; Lee, K. O.; Jee, J.-G.; Chakrabarti, K. S.; de Groot, B. L.; Griesinger, C. et al.; Ryu, K.-S.; Lee, D.: Repositioning food and drug administration-approved drugs for inhibiting Biliverdin IXβ reductase B as a novel thrombocytopenia therapeutic target. Journal of Medicinal Chemistry 65 (3), pp. 2548 - 2557 (2022)

MPG.PuRe

DOI

29.

Journal Article

Karschin, N.; Krenek, S.; Heyer, D.; Griesinger, C.: Extension and improvement of the methanol-d4 NMR thermometer calibration. Magnetic Resonance in Chemistry 60 (2), pp. 203 - 209 (2022)

MPG.PuRe

DOI

30.

Journal Article

Aillaud, I.; Kaniyappan, S.; Chandupatla, R. R.; Ramirez, L. M.; Alkhashrom, S.; Eichler, J.; Horn, A. H. C.; Zweckstetter, M.; Mandelkow, E.-M.; Sticht, H. et al.; Funke, S. A.: A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro. Alzheimer's Research & Therapy 14, 15 (2022)

MPG.PuRe

DOI

publisher-version

31.

Journal Article

Chakrabarti, K. S.; Olsson, S.; Pratihar, S.; Giller, K.; Overkamp, K.; Lee, K. O.; Gapsys, V.; Ryu, K.-S.; de Groot, B. L.; Noé, F. et al.; Becker, S.; Lee, D.; Weikl, T. R.; Griesinger, C.: A litmus test for classifying recognition mechanisms of transiently binding proteins. Nature Communications 13, 3792 (2022)

MPG.PuRe

DOI

publisher-version

32.

Journal Article

Le Marchand, T.; Schubeis, T.; Bonaccorsi, M.; Paluch, P.; Lalli, D.; Pell, A. J.; Andreas, L. B.; Jaudzems, K.; Stanek, J.; Pintacuda, G.: ¹H-Detected Biomolecular NMR under Fast Magic-Angle Spinning. Chemical Reviews 122 (10), pp. 9943 - 10018 (2022)

MPG.PuRe

DOI

publisher-version

33.

Journal Article

Moll, A.; Ramirez, L. M.; Ninov, M.; Schwarz, J.; Urlaub, H.; Zweckstetter, M.: Hsp multichaperone complex buffers pathologically modified Tau. Nature Communications 13, 3668 (2022)

MPG.PuRe

DOI

publisher-version

Publications

Journal Article (33)

Editorial (1)