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Copper binding to the N-terminally acetylated, naturally occurring form of alpha-synuclein induces local helical folding. Journal of the American Chemical Society 252.
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Small molecule-mediated stabilization of vesicle-associated helical alpha-synuclein inhibits pathogenic misfolding and aggregation. Nature Communications 253.
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289 (50), pp. 34620 - 34626 (2014)
Interaction of the intermembrane space domain of Tim23 protein with mitochondrial membranes. Journal of Biological Chemistry 254.
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141, pp. 208 - 211 (2014)
Bioinorganic chemistry of synucleinopathies: Deciphering the binding features of Met motifs and His-50 in AS-Cu(I) interactions. Journal of Inorganic Biochemistry 255.
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60 (4), pp. 231 - 240 (2014)
A six-dimensional alpha proton detection-based APSY experiment for backbone assignment of intrinsically disordered proteins. Journal of Biomolecular NMR 256.
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Long-range correlated dynamics in intrinsically disordered proteins. Journal of the American Chemical Society 257.
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9 (11), e112374 (2014)
NMR-based detection of hydrogen/deuterium exchange in liposome-embedded membrane proteins. PLOS One 258.
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248, pp. 66 - 70 (2014)
EPR moments for site-directed spin-labelling. Journal of Magnetic Resonance 259.
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60 (2-3), pp. 85 - 90 (2014)
Towards automatic protein backbone assignment using proton-detected 4D solid-state NMR data. Journal of Biomolecular NMR 260.
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22 (10), pp. 1501 - 1511 (2014)
Molecular basis of the dynamic structure of the TIM23 complex in the mitochondrial intermembrane space. Structure 261.
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Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex. Nature Structural and Molecular Biology 262.
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70, pp. 149 - 161 (2014)
α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner. Neurobiology of Disease 263.
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High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy. Nature Communications 264.
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53 (39), pp. 10367 - 10371 (2014)
A designed conformational shift to control protein binding specificity. Angewandte Chemie International Edition 265.
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107 (6), pp. 1375 - 1382 (2014)
Water penetration profile at the protein-lipid interface in Na,K-ATPase membranes. Biophysical Journal 266.
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22 (9), pp. 1311 - 1321 (2014)
HIV-1 envelope protein gp41: An NMR study of dodecyl phosphocholine embedded gp41 reveals a dynamic prefusion intermediate conformation. Structure 267.
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5 (9), pp. 3543 - 3551 (2014)
De novo fragment-based design of inhibitors of DXS guided by spin-diffusion-based NMR spectroscopy. Chemical Science 268.
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Macromolecular assembly of the adaptor SLP-65 at intracellular vesicles in resting B cells. Science Signaling 269.
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136 (32), pp. 11280 - 11283 (2014)
Graphene oxide liquid crystals as a versatile and tunable alignment medium for the measurement of residual dipolar couplings in organic solvents. Journal of the American Chemical Society 270.
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23 (8), pp. 1154 - 1160 (2014)
Toward the functional oligomerization state of tryptophan-rich sensory proteins. Protein Science 271.
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30 (15), pp. 2219 - 2220 (2014)
relax: The analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data. Bioinformatics 272.
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Measuring membrane protein bond orientations in nanodiscs via residual dipolar couplings. Protein Science 273.
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243, pp. 107 - 113 (2014)
Quantum mechanical NMR simulation algorithm for protein-size spin systems. Journal of Magnetic Resonance 274.
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289 (19), pp. 13397 - 13406 (2014)
Nucleotide interactions of the human voltage-dependent anion channel. Journal of Biological Chemistry 275.
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53 (9), pp. 4350 - 4358 (2014)
Site-specific copper-catalyzed oxidation of alpha-synuclein: Tightening the link between metal binding and protein oxidative damage in Parkinson's disease. Inorganic Chemistry 276.
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242, pp. 180 - 188 (2014)
Proton-detected MAS NMR experiments based on dipolar transfers for backbone assignment of highly deuterated proteins. Journal of Magnetic Resonance 277.
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127 (5), pp. 779 - 780 (2014)
The oligomer modulator anle138b inhibits disease progression in a Parkinson mouse model even with treatment started after disease onset. Acta Neuropathologica 278.
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59 (1), pp. 15 - 22 (2014)
BSH-CP based 3D solid-state NMR experiments for protein resonance assignment. Journal of Biomolecular NMR 279.
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70 (5), pp. 1321 - 1335 (2014)
Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA. Acta Crystallographica D 280.
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136 (13), pp. 4913 - 4919 (2014)
Turn plasticity distinguishes different modes of amyloid-beta aggregation. Journal of the American Chemical Society 281.
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58 (4), pp. 287 - 301 (2014)
ORIUM: Optimized RDC-based iterative and unified model-free analysis. Journal of Biomolecular NMR 282.
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343 (6177), pp. 1363 - 1366 (2014)
Structure of the mitochondrial translocator protein in complex with a diagnostic ligand. Science 283.
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22 (2), pp. 238 - 249 (2014)
Predictive atomic resolution descriptions of intrinsically disordered hTau40 and alpha-synuclein in solution from NMR and small angle scattering. Structure 284.
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2014 (6), pp. 1147 - 1150 (2014)
Hidden flexibility of strychnine. European Journal of Organic Chemistry 285.
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11 (2), pp. 175 - 182 (2014)
Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes. Nature Methods 286.
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16 (20), pp. 9546 - 9555 (2014)
Voltage-dependent structural changes of the membrane-bound anion channel hVDAC1 probed by SEIRA and electrochemical impedance spectroscopy. Physical Chemistry Chemical Physics 287.
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135 (51), pp. 19135 - 19138 (2013)
Atomic structure and handedness of the building block of a biological assembly. Journal of the American Chemical Society 288.
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19 (51), pp. 17584 - 17588 (2013)
Trapped in misbelief for almost 40 years: Selective synthesis of the four stereoisomers of mefloquine. Chemistry 289.
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21 (12), pp. 2162 - 2174 (2013)
Phosphorylation drives a dynamic switch in serine/arginine-rich proteins. Structure 290.
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191 (11), pp. 5354 - 5358 (2013)
Cutting edge: Feed-forward activation of phospholipase C gamma 2 via C2 domain-mediated binding to SLP65. Journal of Immunology 291.
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2 (6), pp. 912 - 927 (2013)
The cytoplasmic PAS(C) domain of the sensor kinase DcuS of Escherichia coli: Role in signal transduction, dimer formation, and DctA interaction. Microbiologypen 292.
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15 (1), pp. 57 - 60 (2013)
Studies on the MxiH protein in T3SS needles using DNP-enhanced ssNMR spectroscopy. ChemPhysChem 293.
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135 (45), pp. 17111 - 17120 (2013)
Interdomain dynamics explored by paramagnetic NMR. Journal of the American Chemical Society 294.
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185 (1), pp. 69 - 78 (2013)
NMR structural studies of the first catalytic half-domain of ubiquitin activating enzyme. Journal of Structural Biology 295.
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45 (4), pp. 865 - 875 (2013)
Enhanced beta-turn conformational stability of tripeptides containing Delta Phe in cis over trans configuration. Amino Acids 296.
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36 (9), 109 (2013)
X-ray scattering experiments with high-flux X-ray source coupled rapid mixing microchannel device and their potential for high-flux neutron scattering investigations. The European Physical Journal E 297.
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18 (10), pp. 11904 - 11937 (2013)
Measuring dynamic and kinetic information in the previously inaccessible Supra-tc window of nanoseconds to microseconds by solution NMR spectroscopy. Molecules 298.
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52 (39), pp. 10290 - 10294 (2013)
Long-range distances in amyloid fibrils of α-synuclein from PELDOR spectroscopy. Angewandte Chemie International Edition 299.
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57 (1), pp. 73 - 82 (2013)
Enhanced accuracy of kinetic information from CT-CPMG experiments by transverse rotating-frame spectroscopy. Journal of Biomolecular NMR 300.
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74 (1), pp. 109 - 118 (2013)
Beta-synuclein aggregates and induces neurodegeneration in dopaminergic neurons. Annals of Neurology