Publikationen
Zeitschriftenartikel (40)
1.
Zeitschriftenartikel
52, S. 391 - 411 (2023)
Prospects and Limitations of High-Resolution Single-Particle Cryo-Electron Microscopy. Annual Review of Biophysics 2.
Zeitschriftenartikel
EIGER2 hybrid-photon-counting X-ray detectors for advanced synchrotron diffraction experiments. Journal of Synchrotron Radiation, 30 (2023)
3.
Zeitschriftenartikel
50 (9), S. 5282 - 5298 (2022)
Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Research 4.
Zeitschriftenartikel
11, 1289 (2021)
Chromatography-free purification strategies for large biological macromolecular complexes involving fractionated PEG precipitation and density gradients. Life 5.
Zeitschriftenartikel
11 (12), 1289 (2021)
Chromatography-free purification strategies for large biological macromolecular complexes involving fractionated PEG precipitation and density gradients. Life 6.
Zeitschriftenartikel
587 (7832), S. 157 - 161 (2020)
Atomic-resolution protein structure determination by cryo-EM. Nature 7.
Zeitschriftenartikel
6 (30), eaba3916 (2020)
Proteasomal degradation of the intrinsically disordered protein tau at single-residue resolution. Science Advances 8.
Zeitschriftenartikel
180 (6), S. 1130 - 1143.e20 (2020)
Discovery of a regulatory subunit of the yeast fatty acid synthase. Cell 9.
Zeitschriftenartikel
27 (7), S. 1124 - 1136 (2019)
Structural and functional analyses of the human PDH complex suggest a "Division-of-Labor" mechanism by local E1 and E3 clusters. Structure 10.
Zeitschriftenartikel
17 (7), S. 471 - 492 (2018)
Cryo-EM in drug discovery: Achievements, limitations and prospects. Nature Reviews Drug Discovery 11.
Zeitschriftenartikel
8, 15578 (2017)
Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs. Nature Communications 12.
Zeitschriftenartikel
353 (6306), S. 1399 - 1405 (2016)
Molecular architecture of the Saccharomyces cerevisiae activated spliceosome. Science 13.
Zeitschriftenartikel
16 (12), S. 3103 - 3112 (2016)
The ribosome cooperates with the assembly chaperone pICln to initiate formation of snRNPs. Cell Reports 14.
Zeitschriftenartikel
353 (6299), S. 594 - 598 (2016)
The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science 15.
Zeitschriftenartikel
65 (1), S. 23 - 34 (2016)
Sample preparation of biological macromolecular assemblies for the determination of high-resolution structures by cryo-electron microscopy. Microscopy 16.
Zeitschriftenartikel
12 (9), S. 859 - 865 (2015)
ProteoPlex: Stability optimization of macromolecular complexes by sparse-matrix screening of chemical space. Nature Methods 17.
Zeitschriftenartikel
34 (14), S. 1925 - 1941 (2015)
Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organization. EMBO Journal 18.
Zeitschriftenartikel
21 (4), S. 613 - 614 (2015)
Assembly of RNPs: help needed. RNA 19.
Zeitschriftenartikel
26 (2), S. 161 - 171 (2015)
The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization. Molecular Biology of the Cell 20.
Zeitschriftenartikel
22 (6), S. 923 - 930 (2014)
Translation initiation factor eIF3b contains a nine-bladed beta-propeller and interacts with the 40S ribosomal subunit. Structure 21.
Zeitschriftenartikel
93 (3), S. 106 - 117 (2014)
Phosphoregulation of the human SMN complex. European Journal of Cell Biology 22.
Zeitschriftenartikel
49 (4), S. 692 - 703 (2013)
Structural basis of assembly chaperone- mediated snRNP formation. Molecular Cell 23.
Zeitschriftenartikel
2 (5), S. 718 - 731 (2011)
Biogenesis of spliceosomal small nuclear ribonucleoproteins. Wiley Interdisciplinary Reviews: RNA 24.
Zeitschriftenartikel
35 (12), S. 676 - 683 (2010)
Cellular strategies for the assembly of molecular machines. Trends in biochemical sciences 25.
Zeitschriftenartikel
16 (8), S. 1646 - 1659 (2010)
Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I. RNA 26.
Zeitschriftenartikel
66 (6), S. 685 - 697 (2010)
A crystallization screen based on alternative polymeric precipitants. Acta Crystallographica Section D 27.
Zeitschriftenartikel
16 (4), S. 817 - 827 (2010)
LSm1-7 complexes bind to specific sites in viral RNA genomes and regulate their translation and replication. RNA 28.
Zeitschriftenartikel
106 (32), S. 13517 - 13522 (2009)
Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates. Proceedings of the National Academy of Sciences of the USA 29.
Zeitschriftenartikel
21 (3), S. 387 - 393 (2009)
The role of RNP biogenesis in spinal muscular atrophy. Current Opinion in Cell Biology 30.
Zeitschriftenartikel
18 (7), S. 1288 - 1300 (2009)
IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1). Human Molecular Genetics 31.
Zeitschriftenartikel
15 (5), S. 484 - 487 (2009)
Molekulares Bodybuilding: Wie Zellen RNA-Proteinkomplexe herstellen. BioSpektrum 32.
Zeitschriftenartikel
135 (3), S. 497 - 509 (2008)
An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs. Cell 33.
Zeitschriftenartikel
105 (29), S. 10045 - 10050 (2008)
Evolution of an RNP assembly system: A minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the USA 34.
Zeitschriftenartikel
582 (14), S. 1997 - 2003 (2008)
Deciphering the assembly pathway of Sm‐class U snRNPs. FEBS Letters 35.
Zeitschriftenartikel
368 (2), S. 178 - 184 (2007)
A 5′-fluorosulfonylbenzoyladenosine-based method to identify physiological substrates of a Drosophila p21-activated kinase. Analytical Biochemistry 36.
Zeitschriftenartikel
282 (8), S. 5825 - 5833 (2007)
A comprehensive interaction map of the human survival of motor neuron (SMN) complex. Journal of Biological Chemistry 37.
Zeitschriftenartikel
13 (6), S. 610 - 613 (2007)
Wenn Muskeln die Nerven verlieren. Biospektrum 38.
Zeitschriftenartikel
12 (3), S. 113 - 121 (2006)
Spinal muscular atrophy: the RNP connection. Trends in Molecular Medicine 39.
Zeitschriftenartikel
14 (20), S. 3099 - 3111 (2005)
Unrip, a factor implicated in cap-independent translation, associates with the cytosolic SMN complex and influences its intracellular localization. Human Molecular Genetics 40.
Zeitschriftenartikel
280 (41), S. 34435 - 34440 (2005)
Toward an assembly line for U7 snRNPs - Interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes. Journal of Biological Chemistry Buchkapitel (1)
41.
Buchkapitel
Fatty Acid Synthase: Structure, Function, and Regulation. In: Macromolecular Protein Complexes IV: Structure and Function, S. 1 - 33 (Hg. Harris, R.; Marles-Wright, J.). Springer, Cham (2022)